We measure the time-resolved terahertz spectroscopy of GeSn thin film and studied the ultrafast dynamics of its photo-generated carriers.The experimental results show that there are photo-generated carriers in GeSn un...We measure the time-resolved terahertz spectroscopy of GeSn thin film and studied the ultrafast dynamics of its photo-generated carriers.The experimental results show that there are photo-generated carriers in GeSn under femtosecond laser excitation at 2500 nm,and its pump-induced photoconductivity can be explained by the Drude–Smith model.The carrier recombination process is mainly dominated by defect-assisted Auger processes and defect capture.The firstand second-order recombination rates are obtained by the rate equation fitting,which are(2.6±1.1)×10^(-2)ps^(-1)and(6.6±1.8)×10^(-19)cm^(3)·ps^(-1),respectively.Meanwhile,we also obtain the diffusion length of photo-generated carriers in GeSn,which is about 0.4μm,and it changes with the pump delay time.These results are important for the GeSn-based infrared optoelectronic devices,and demonstrate that Ge Sn materials can be applied to high-speed optoelectronic detectors and other applications.展开更多
Urban traffic volume detection is an essential part of trafficplanning in terms of urban planning in China. To improve the statisticsefficiency of road traffic volume, this thesis proposes a method for predictingmotor...Urban traffic volume detection is an essential part of trafficplanning in terms of urban planning in China. To improve the statisticsefficiency of road traffic volume, this thesis proposes a method for predictingmotor vehicle traffic volume on urban roads in small and medium-sizedcities during the traffic peak hour by using mobile signal technology. Themethod is verified through simulation experiments, and the limitations andthe improvement methods are discussed. This research can be divided intothree parts: Firstly, the traffic patterns of small and medium-sized cities areobtained through a questionnaire survey. A total of 19745 residents weresurveyed in Luohe, a medium-sized city in China and five travel modes oflocal people were obtained. Secondly, after the characteristics of residents’rest and working time are investigated, a method is proposed in this studyfor the distribution of urban residential and working places based on mobilephone signaling technology. Finally, methods for predicting traffic volume ofthese travel modes are proposed after the characteristics of these travel modesand methods for the distribution of urban residential and working placesare analyzed. Based on the actual traffic volume data observed at offlineintersections, the project team takes Luohe city as the research object and itverifies the accuracy of the prediction method by comparing the predictiondata. The prediction simulation results of traffic volume show that the averageerror rate of traffic volume is unstable. The error rate ranges from 10% to 30%.In this thesis, simulation experiments and field investigations are adopted toanalyze why these errors occur.展开更多
Nonlinear optical properties are investigated using the static and time-resolved second harmonic generation in the topological material molybdenum phosphide(Mo P) with three-component fermions.Giant second harmonic ge...Nonlinear optical properties are investigated using the static and time-resolved second harmonic generation in the topological material molybdenum phosphide(Mo P) with three-component fermions.Giant second harmonic generation signals are detected and the derived χ^((2)) value is larger than that of the typical electro–optic material.Upon optical excitation,no photoinduced change of the symmetry is detected in MoP,which is quite different from previous observations in several other topological materials.展开更多
AIM: To compare long-term outcome of primary and recurrent pterygium surgery with three different techniques: combined conjunctival autograft and overlay amniotic membrane transplantation(CAT with AMT), conjunctival a...AIM: To compare long-term outcome of primary and recurrent pterygium surgery with three different techniques: combined conjunctival autograft and overlay amniotic membrane transplantation(CAT with AMT), conjunctival autograft transplantation(CAT) alone and amniotic membrane transplantation(AMT) alone.METHODS: In this retrospective study, 142 eyes of 142 pterygium patients(104 primary, 38 recurrent) who underwent CAT(group A), AMT(group B) or CAT with AMT(group C) respectively following surgical excision were reviewed and compared based on the recurrences and post-operative complications.RESULTS: The number of recurrence post-surgery were 17(9 from primary, 8 from recurrent; the same description below), 18(10, 8) and 2(1, 1) in groups A, B, and C respectively; dry eyes were 22(16, 6), 27(18, 9) and 7(3, 4); conjunctival inflammations were 30(17, 13), 27(16, 11) and 11(6, 5). Patients in group C(either primary or recurrent or both) mainly showed significantly better results than those in group A or B(P<0.05) regarding above-mentioned clinical effects.CONCLUSION: Combined CAT and overly AMT have significantly lower rates of recurrence and postoperative complications for primary and recurrent pterygium surgery than CAT or AMT alone.展开更多
Background: Methionine is an essential amino acid for fish. The present study was conducted to investigate the effects of dietary methionine on growth performance, digestive and absorptive ability, as well as antioxid...Background: Methionine is an essential amino acid for fish. The present study was conducted to investigate the effects of dietary methionine on growth performance, digestive and absorptive ability, as well as antioxidant capacity in the intestine and hepatopancreas of sub-adult grass carp(Ctenopharyngodon idella).Results: Dietary methionine deficiency significantly decreased percentage weight gain(PWG), feed intake, feed efficiency and protein efficiency ratio, as well as activities of hepatopancreatic glutamate-oxaloacetate transaminase and muscle glutamate-pyruvate transaminase in sub-adult grass carp(P < 0.05). Furthermore, methionine deficiency significantly reduced activities of trypsin, lipase and amylase in the intestine, Na^+/K^+-ATPase, alkaline phosphatase and γ-glutamyl transpeptidase in three intestinal segments, and creatine kinase(CK) in the proximal intestine(P < 0.05). However, an unexplained and significant increase in CK activity in the mid intestine was associated with dietary methionine deficiency. Malondialdehyde and protein carbonyl contents in the intestine and hepatopancreas were significantly increased by methionine deficiency(P < 0.05), whereas anti-hydroxyl radical capacity in the hepatopancreas and intestine, and anti-superoxide anion capacity in the intestine, were significantly decreased by methionine deficiency(P < 0.05). Moreover, methionine deficiency significantly decreased superoxide dismutase and glutathione reductase activities, glutathione contents in the hepatopancreas and intestine, as well as glutathione peroxidase activity in the intestine(P < 0.05), whereas it significantly increased activities of catalase in the hepatopancreas and glutathione-S-transferase in the hepatopancreas and intestine(P < 0.05).(Continued on next page)(Continued from previous page)Conclusions: The present results demonstrated that dietary methionine deficiency induced poor growth, and decreased digestive and absorptive function and antioxidant capacity in the hepatopancreas and intestine of sub-adult grass carp. Methionine requirements for sub-adult grass carp(450-1, 170 g) based on PWG, intestinal trypsin, and hepatopancreatic anti-hydroxyl radical activities were estimated to be 6.12 g/kg diet(21.80 g/kg protein),6.99 g/kg diet(24.90 g/kg protein) and 5.42 g/kg diet(19.31 g/kg protein), respectively, in the presence of 1.50 g cysteine/kg(5.35 g/kg protein).展开更多
Background:This study was carried out to investigate effects of threonine levels on growth,digestive and absorptive capacity and antioxidant status in intestine and hepatopancreas of sub-adult grass carp(Ctenopharyngo...Background:This study was carried out to investigate effects of threonine levels on growth,digestive and absorptive capacity and antioxidant status in intestine and hepatopancreas of sub-adult grass carp(Ctenopharyngodonidella).Results:Weight gain,specific growth rate,feed intake and feed efficiency were significantly improved by dietary threonine(P<0.05).Intestinal activities of trypsin,chymotrypsin,alpha-amylase,lipase,alkaline phosphatase,y-glutamyl transpeptidase and creatine kinase took the similar trends.Contents of malondialdehyde and protein carbonyl in intestine and hepatopancreas were significantly decreased by dietary optimal threonine supplementation(P<0.05).Anti-superoxide anion capacity,anti-hydroxyl radical capacity,glutathione content and activities of superoxide dismutase,catalase and glutathione-S-transferase in intestine and hepatopancreas were enhanced by dietary threonine(P< 0.05).Conclusions:Dietary threonine could improve growth,enhance digestive and absorptive capacity and antioxidant status in intestine and hepatopancreas of sub-adult grass carp.The dietary threonine requirement of sub-adult grass carp(441.9-1,013.4 g) based on weight gain was 11.6 g/kg diet or 41.5 g/kg of dietary protein by quadratic regression analysis.展开更多
AIM: To investigate whether DNA vaccine encoding herpes simplex virus 1(HSV-1) glycoprotein C(g C) and glycoprotein D(g D) will achieve better protective effect against herpes simplex keratitis(HSK) than DNA vaccine e...AIM: To investigate whether DNA vaccine encoding herpes simplex virus 1(HSV-1) glycoprotein C(g C) and glycoprotein D(g D) will achieve better protective effect against herpes simplex keratitis(HSK) than DNA vaccine encoding gD alone. METHODS: DNA vaccine expressing gD or gC combined g D(g D.g C) were constructed and carried by chitosan nanoparticle. The expression of fusion protein gD and gC were detected in DNA/nanoparticle transfected 293 T cells by Western-blot. For immunization, mice were inoculated with DNA/nanoparticle for 3 times with 2 wk interval, and two weeks after the final immunization, the specific immune responses and clinical degrees of primary HSK were evaluated. RESULTS: Fusion protein g D.g C could be expressed successfully in cultured 293 T cells. And, p RSC-g C.g DIL21 DNA/chitosan nanoparticle could effectively elicit strongest humoral and cellular immune response in primary HSK mice evidenced by higher levels of specific neutralizing antibody and s Ig A production, enhanced cytotoxicities of splenocytes and nature killer cells(NK),when compared with those of gD alone or mocked vaccine immunized mice. As a result, gC-based vaccine immunized mice showed least HSK disease. CONCLUSION: gC-based DNA vaccine could effectively prevent the progress of primary HSK, suggesting that this DNA vaccine could be a promising vaccine for HSK treatment in the future.展开更多
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12004067,11974070,62027807,and 52272137)the National Key R&D Program of China(Grant No.2022YFA1403000)。
文摘We measure the time-resolved terahertz spectroscopy of GeSn thin film and studied the ultrafast dynamics of its photo-generated carriers.The experimental results show that there are photo-generated carriers in GeSn under femtosecond laser excitation at 2500 nm,and its pump-induced photoconductivity can be explained by the Drude–Smith model.The carrier recombination process is mainly dominated by defect-assisted Auger processes and defect capture.The firstand second-order recombination rates are obtained by the rate equation fitting,which are(2.6±1.1)×10^(-2)ps^(-1)and(6.6±1.8)×10^(-19)cm^(3)·ps^(-1),respectively.Meanwhile,we also obtain the diffusion length of photo-generated carriers in GeSn,which is about 0.4μm,and it changes with the pump delay time.These results are important for the GeSn-based infrared optoelectronic devices,and demonstrate that Ge Sn materials can be applied to high-speed optoelectronic detectors and other applications.
文摘Urban traffic volume detection is an essential part of trafficplanning in terms of urban planning in China. To improve the statisticsefficiency of road traffic volume, this thesis proposes a method for predictingmotor vehicle traffic volume on urban roads in small and medium-sizedcities during the traffic peak hour by using mobile signal technology. Themethod is verified through simulation experiments, and the limitations andthe improvement methods are discussed. This research can be divided intothree parts: Firstly, the traffic patterns of small and medium-sized cities areobtained through a questionnaire survey. A total of 19745 residents weresurveyed in Luohe, a medium-sized city in China and five travel modes oflocal people were obtained. Secondly, after the characteristics of residents’rest and working time are investigated, a method is proposed in this studyfor the distribution of urban residential and working places based on mobilephone signaling technology. Finally, methods for predicting traffic volume ofthese travel modes are proposed after the characteristics of these travel modesand methods for the distribution of urban residential and working placesare analyzed. Based on the actual traffic volume data observed at offlineintersections, the project team takes Luohe city as the research object and itverifies the accuracy of the prediction method by comparing the predictiondata. The prediction simulation results of traffic volume show that the averageerror rate of traffic volume is unstable. The error rate ranges from 10% to 30%.In this thesis, simulation experiments and field investigations are adopted toanalyze why these errors occur.
基金supported by the National Key R&D Program of China(Grant No.2022YFA1403000)the National Natural Science Foundation of China(Grant Nos.11974070,92365102,11974306,12034017,11734006,and 11774401)。
文摘Nonlinear optical properties are investigated using the static and time-resolved second harmonic generation in the topological material molybdenum phosphide(Mo P) with three-component fermions.Giant second harmonic generation signals are detected and the derived χ^((2)) value is larger than that of the typical electro–optic material.Upon optical excitation,no photoinduced change of the symmetry is detected in MoP,which is quite different from previous observations in several other topological materials.
基金Supported by Natural Science Foundation of Jiangsu Province(No.BK20141346)Nanjing Science and Technology Development Plan(No.201402001)
文摘AIM: To compare long-term outcome of primary and recurrent pterygium surgery with three different techniques: combined conjunctival autograft and overlay amniotic membrane transplantation(CAT with AMT), conjunctival autograft transplantation(CAT) alone and amniotic membrane transplantation(AMT) alone.METHODS: In this retrospective study, 142 eyes of 142 pterygium patients(104 primary, 38 recurrent) who underwent CAT(group A), AMT(group B) or CAT with AMT(group C) respectively following surgical excision were reviewed and compared based on the recurrences and post-operative complications.RESULTS: The number of recurrence post-surgery were 17(9 from primary, 8 from recurrent; the same description below), 18(10, 8) and 2(1, 1) in groups A, B, and C respectively; dry eyes were 22(16, 6), 27(18, 9) and 7(3, 4); conjunctival inflammations were 30(17, 13), 27(16, 11) and 11(6, 5). Patients in group C(either primary or recurrent or both) mainly showed significantly better results than those in group A or B(P<0.05) regarding above-mentioned clinical effects.CONCLUSION: Combined CAT and overly AMT have significantly lower rates of recurrence and postoperative complications for primary and recurrent pterygium surgery than CAT or AMT alone.
基金supported by the National Basic Research Program of China(973 Program)(2014CB138600)National Science Foundation of China(31502184)+7 种基金Outstanding Talents and Innovative Team of Agricultural Scientific Research(Ministry of Agriculture)the National Department Public Benefit Research Foundation(Agriculture)of China(201003020)the Specialized Research Fund for the Doctoral Program of Higher Education of China(20135103110001)Science and Technology Support Program of Sichuan Province of China(2014NZ0003)Major Scientific and Technological Achievement Transformation Project of Sichuan Province of China(2012NC00072013NC0045)the Demonstration of Major Scientific and Technological Achievement Transformation Project of Sichuan Province of China(2015CC0011)Natural Science Foundation for Young Scientists of Sichuan Province(2014JQ0007)
文摘Background: Methionine is an essential amino acid for fish. The present study was conducted to investigate the effects of dietary methionine on growth performance, digestive and absorptive ability, as well as antioxidant capacity in the intestine and hepatopancreas of sub-adult grass carp(Ctenopharyngodon idella).Results: Dietary methionine deficiency significantly decreased percentage weight gain(PWG), feed intake, feed efficiency and protein efficiency ratio, as well as activities of hepatopancreatic glutamate-oxaloacetate transaminase and muscle glutamate-pyruvate transaminase in sub-adult grass carp(P < 0.05). Furthermore, methionine deficiency significantly reduced activities of trypsin, lipase and amylase in the intestine, Na^+/K^+-ATPase, alkaline phosphatase and γ-glutamyl transpeptidase in three intestinal segments, and creatine kinase(CK) in the proximal intestine(P < 0.05). However, an unexplained and significant increase in CK activity in the mid intestine was associated with dietary methionine deficiency. Malondialdehyde and protein carbonyl contents in the intestine and hepatopancreas were significantly increased by methionine deficiency(P < 0.05), whereas anti-hydroxyl radical capacity in the hepatopancreas and intestine, and anti-superoxide anion capacity in the intestine, were significantly decreased by methionine deficiency(P < 0.05). Moreover, methionine deficiency significantly decreased superoxide dismutase and glutathione reductase activities, glutathione contents in the hepatopancreas and intestine, as well as glutathione peroxidase activity in the intestine(P < 0.05), whereas it significantly increased activities of catalase in the hepatopancreas and glutathione-S-transferase in the hepatopancreas and intestine(P < 0.05).(Continued on next page)(Continued from previous page)Conclusions: The present results demonstrated that dietary methionine deficiency induced poor growth, and decreased digestive and absorptive function and antioxidant capacity in the hepatopancreas and intestine of sub-adult grass carp. Methionine requirements for sub-adult grass carp(450-1, 170 g) based on PWG, intestinal trypsin, and hepatopancreatic anti-hydroxyl radical activities were estimated to be 6.12 g/kg diet(21.80 g/kg protein),6.99 g/kg diet(24.90 g/kg protein) and 5.42 g/kg diet(19.31 g/kg protein), respectively, in the presence of 1.50 g cysteine/kg(5.35 g/kg protein).
基金National 973 Project of China(2014CB138600)National Department Public Benefit Research Foundation(Agriculture) of China (201003020)+1 种基金Science and Technology Support Programme of Sichuan Province of China(2014NZ0003)Major Scientific and Technological Achievement Transformation Project of Sichuan Province of China(2012NC0007 and 2013NC0045) for their financial support
文摘Background:This study was carried out to investigate effects of threonine levels on growth,digestive and absorptive capacity and antioxidant status in intestine and hepatopancreas of sub-adult grass carp(Ctenopharyngodonidella).Results:Weight gain,specific growth rate,feed intake and feed efficiency were significantly improved by dietary threonine(P<0.05).Intestinal activities of trypsin,chymotrypsin,alpha-amylase,lipase,alkaline phosphatase,y-glutamyl transpeptidase and creatine kinase took the similar trends.Contents of malondialdehyde and protein carbonyl in intestine and hepatopancreas were significantly decreased by dietary optimal threonine supplementation(P<0.05).Anti-superoxide anion capacity,anti-hydroxyl radical capacity,glutathione content and activities of superoxide dismutase,catalase and glutathione-S-transferase in intestine and hepatopancreas were enhanced by dietary threonine(P< 0.05).Conclusions:Dietary threonine could improve growth,enhance digestive and absorptive capacity and antioxidant status in intestine and hepatopancreas of sub-adult grass carp.The dietary threonine requirement of sub-adult grass carp(441.9-1,013.4 g) based on weight gain was 11.6 g/kg diet or 41.5 g/kg of dietary protein by quadratic regression analysis.
基金Supported by Natural Science Foundation of Jiangsu Province (No.BK20141346)Nanjing Science and Technology Development Plan (No.201402001)
文摘AIM: To investigate whether DNA vaccine encoding herpes simplex virus 1(HSV-1) glycoprotein C(g C) and glycoprotein D(g D) will achieve better protective effect against herpes simplex keratitis(HSK) than DNA vaccine encoding gD alone. METHODS: DNA vaccine expressing gD or gC combined g D(g D.g C) were constructed and carried by chitosan nanoparticle. The expression of fusion protein gD and gC were detected in DNA/nanoparticle transfected 293 T cells by Western-blot. For immunization, mice were inoculated with DNA/nanoparticle for 3 times with 2 wk interval, and two weeks after the final immunization, the specific immune responses and clinical degrees of primary HSK were evaluated. RESULTS: Fusion protein g D.g C could be expressed successfully in cultured 293 T cells. And, p RSC-g C.g DIL21 DNA/chitosan nanoparticle could effectively elicit strongest humoral and cellular immune response in primary HSK mice evidenced by higher levels of specific neutralizing antibody and s Ig A production, enhanced cytotoxicities of splenocytes and nature killer cells(NK),when compared with those of gD alone or mocked vaccine immunized mice. As a result, gC-based vaccine immunized mice showed least HSK disease. CONCLUSION: gC-based DNA vaccine could effectively prevent the progress of primary HSK, suggesting that this DNA vaccine could be a promising vaccine for HSK treatment in the future.
