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Personalized assessment and training of neurosurgical skills in virtual reality:An interpretable machine learning approach
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作者 Fei LI Zhibao QIN +3 位作者 kai qian Shaojun LIANG Chengli LI Yonghang TAI 《虚拟现实与智能硬件(中英文)》 EI 2024年第1期17-29,共13页
Background Virtual reality technology has been widely used in surgical simulators,providing new opportunities for assessing and training surgical skills.Machine learning algorithms are commonly used to analyze and eva... Background Virtual reality technology has been widely used in surgical simulators,providing new opportunities for assessing and training surgical skills.Machine learning algorithms are commonly used to analyze and evaluate the performance of participants.However,their interpretability limits the personalization of the training for individual participants.Methods Seventy-nine participants were recruited and divided into three groups based on their skill level in intracranial tumor resection.Data on the use of surgical tools were collected using a surgical simulator.Feature selection was performed using the Minimum Redundancy Maximum Relevance and SVM-RFE algorithms to obtain the final metrics for training the machine learning model.Five machine learning algorithms were trained to predict the skill level,and the support vector machine performed the best,with an accuracy of 92.41%and Area Under Curve value of 0.98253.The machine learning model was interpreted using Shapley values to identify the important factors contributing to the skill level of each participant.Results This study demonstrates the effectiveness of machine learning in differentiating the evaluation and training of virtual reality neurosurgical performances.The use of Shapley values enables targeted training by identifying deficiencies in individual skills.Conclusions This study provides insights into the use of machine learning for personalized training in virtual reality neurosurgery.The interpretability of the machine learning models enables the development of individualized training programs.In addition,this study highlighted the potential of explanatory models in training external skills. 展开更多
关键词 Machine learning NEUROSURGERY Shapley values Virtual reality Human-robot interaction
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Cloud computing-enabled IIOT system for neurosurgical simulation using augmented reality data acces
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作者 Jun Liu kai qian +3 位作者 Zhibao Qin Mohammad Dahman Alshehri Qiong Li Yonghang Tai 《Digital Communications and Networks》 SCIE CSCD 2023年第2期347-357,共11页
In recent years,statistics have indicated that the number of patients with malignant brain tumors has increased sharply.However,most surgeons still perform surgical training using the traditional autopsy and prosthesi... In recent years,statistics have indicated that the number of patients with malignant brain tumors has increased sharply.However,most surgeons still perform surgical training using the traditional autopsy and prosthesis model,which encounters many problems,such as insufficient corpse resources,low efficiency,and high cost.With the advent of the 5G era,a wide range of Industrial Internet of Things(IIOT)applications have been developed.Virtual Reality(VR)and Augmented Reality(AR)technologies that emerged with 5G are developing rapidly for intelligent medical training.To address the challenges encountered during neurosurgery training,and combining with cloud computing,in this paper,a highly immersive AR-based brain tumor neurosurgery remote collaborative virtual surgery training system is developed,in which a VR simulator is embedded.The system enables real-time remote surgery training interaction through 5G transmission.Six experts and 18 novices were invited to participate in the experiment to verify the system.Subsequently,the two simulators were evaluated using face and construction validation methods.The results obtained by training the novices 50 times were further analyzed using the Learning Curve-Cumulative Sum(LC-CUSUM)evaluation method to validate the effectiveness of the two simulators.The results of the face and content validation demonstrated that the AR simulator in the system was superior to the VR simulator in terms of vision and scene authenticity,and had a better effect on the improvement of surgical skills.Moreover,the surgical training scheme proposed in this paper is effective,and the remote collaborative training effect of the system is ideal. 展开更多
关键词 NEUROSURGERY IIOT Cloud computing Intelligent medical 5G AR
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电磁导航支气管镜活检联合Massage染色定位在肺疾病诊疗中的应用 被引量:6
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作者 钱凯 冯涌耕 +2 位作者 王如文 邓波 谭群友 《中国肺癌杂志》 CAS CSCD 北大核心 2019年第1期15-19,共5页
背景与目的电磁导航支气管镜(electromagnetic navigation bronchoscope, ENB)因无创、准确、实时等特点,是目前最新的微创诊疗技术。本研究探讨ENB活检联合一种新颖的Massage染色定位技术在肺周围型病变(peripheral pulmonary lesion, ... 背景与目的电磁导航支气管镜(electromagnetic navigation bronchoscope, ENB)因无创、准确、实时等特点,是目前最新的微创诊疗技术。本研究探讨ENB活检联合一种新颖的Massage染色定位技术在肺周围型病变(peripheral pulmonary lesion, PPL)诊治中的应用。方法回顾分析陆军军医大学大坪医院胸外科2017年8月-2018年1月施行ENB活检联合Massage染色定位的15例PPL患者的临床资料。其中,男性12例、女性3例,年龄(51.3±2.1)岁。结果 15例PPL直径6 mm-36 mm,平均14.0 mm。活检成功率66.7%。15例均成功行Massage染色定位。染色部位中心距离病灶中心(1.0±0.4)cm,染色扩散直径(2.8±0.6)cm。操作时间为(26.7±5.3)min,术中失血量(3.3±1.5)mL。操作过程中无气胸、大出血及气管损伤。结论该技术损伤小、并发症率低、精度高、一站式完成诊断及定位,值得推广。 展开更多
关键词 电磁导航支气管镜 活检 肺周围型病变 定位
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Effects of neural stem cell transplantation on the motor function of rats with contusion spinal cord injuries:a meta-analysis 被引量:4
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作者 kai qian Tuo-Ye Xu +7 位作者 Xi Wang Tao Ma kai-Xin Zhang Kun Yang Teng-Da qian Jing Shi Li-Xin Li Zheng Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2020年第4期748-758,共11页
Objective:To judge the efficacies of neural stem cell(NSC)transplantation on functional recovery following contusion spinal cord injuries(SCIs).Data sources:Studies in which NSCs were transplanted into a clinically re... Objective:To judge the efficacies of neural stem cell(NSC)transplantation on functional recovery following contusion spinal cord injuries(SCIs).Data sources:Studies in which NSCs were transplanted into a clinically relevant,standardized rat model of contusion SCI were identified by searching the PubMed,Embase and Cochrane databases,and the extracted data were analyzed by Stata 14.0.Data selection:Inclusion criteria were that NSCs were used in in vivo animal studies to treat contusion SCIs and that behavioral assessment of locomotor functional recovery was performed using the Basso,Beattie,and Bresnahan lo-comotor rating scale.Exclusion criteria included a follow-up of less than 4 weeks and the lack of control groups.Outcome measures:The restoration of motor function was assessed by the Basso,Beattie,and Bresnahan locomotor rating scale.Results:We identified 1756 non-duplicated papers by searching the aforementioned electronic databases,and 30 full-text articles met the inclusion criteria.A total of 37 studies reported in the 30 articles were included in the meta-analysis.The meta-analysis results showed that transplanted NSCs could improve the motor function recovery of rats following contusion SCIs,to a moderate extent(pooled standardized mean difference(SMD)=0.73;95%confidence interval(CI):0.47–1.00;P<0.001).NSCs obtained from different donor species(rat:SMD=0.74;95%CI:0.36–1.13;human:SMD=0.78;95%CI:0.31–1.25),at different donor ages(fetal:SMD=0.67;95%CI:0.43–0.92;adult:SMD=0.86;95%CI:0.50–1.22)and from different origins(brain-derived:SMD=0.59;95%CI:0.27–0.91;spinal cord-derived:SMD=0.51;95%CI:0.22–0.79)had similar efficacies on improved functional recovery;however,adult induced pluripotent stem cell-derived NSCs showed no significant efficacies.Furthermore,the use of higher doses of transplanted NSCs or the administration of immunosuppressive agents did not promote better locomotor function recovery(SMD=0.45;95%CI:0.21–0.70).However,shorter periods between the contusion induction and the NSC transplantation showed slightly higher efficacies(acute:SMD=1.22;95%CI:0.81–1.63;subacute:SMD=0.75;95%CI:0.42–1.09).For chronic injuries,NSC implantation did not significantly improve functional recovery(SMD=0.25;95%CI:–0.16 to 0.65).Conclusion:NSC transplantation alone appears to be a positive yet limited method for the treatment of contusion SCIs. 展开更多
关键词 Basso Beattie and Bresnahan locomotor rating scale CELL TRANSPLANTATION META-ANALYSIS motor functional recovery NEURAL regeneration NEURAL stem CELL NEURAL stem CELL TRANSPLANTATION rat model SPINAL CONTUSION SPINAL cord injury
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Tunable electronic properties of GaS-SnS_(2)heterostructure by strain and electric field 被引量:1
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作者 任达华 李强 +1 位作者 钱楷 谭兴毅 《Chinese Physics B》 SCIE EI CAS CSCD 2022年第4期583-588,共6页
Vertically stacked heterostructures have received extensive attention because of their tunable electronic structures and outstanding optical properties.In this work,we study the structural,electronic,and optical prope... Vertically stacked heterostructures have received extensive attention because of their tunable electronic structures and outstanding optical properties.In this work,we study the structural,electronic,and optical properties of vertically stacked GaS-SnS_(2)heterostructure under the frame of density functional theory.We find that the stacked GaS-SnS_(2)heterostructure is a semiconductor with a suitable indirect band gap of 1.82 eV,exhibiting a type-Ⅱband alignment for easily separating the photo-generated carriers.The electronic properties of GaS-SnS_(2)hetero structure can be effectively tuned by an external strain and electric field.The optical absorption of GaS-SnS_(2)heterostructure is more enhanced than those of the GaS monolayer and SnS_(2)monolayer in the visible light region.Our results suggest that the GaS-SnS_(2)hetero structure is a promising candidate for the photocatalyst and photoelectronic devices in the visible light region. 展开更多
关键词 GaS-SnS_(2)heterostructure type-Ⅱband alignment optical properties density functional theory
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Experimental Synthesis of Strained Monolayer Silver Arsenide on Ag(111)Substrates
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作者 张帅 宋洋 +12 位作者 李航 李金梅 钱凯 刘晨 王嘉鸥 钱天 张余洋 卢建臣 丁洪 林晓 潘金波 杜世萱 高鸿钧 《Chinese Physics Letters》 SCIE CAS CSCD 2020年第6期111-114,共4页
Two-dimensional(2 D)materials are playing more and more important roles in both basic sciences and industrial applications.For 2 D materials,strain could tune the properties and enlarge applications.Since the growth o... Two-dimensional(2 D)materials are playing more and more important roles in both basic sciences and industrial applications.For 2 D materials,strain could tune the properties and enlarge applications.Since the growth of 2 D materials on substrates is often accompanied by strain,the interaction between 2 D materials and substrates is worthy of careful attention.Here we demonstrate the fabrication of strained monolayer silver arsenide(AgAs)on Ag(111)by molecular beam epitaxy,which shows one-dimensional stripe structures arising from uniaxial strain.The atomic geometric structure and electronic band structure are investigated by low energy electron diffraction,scanning tunneling microscopy,x-ray photoelectron spectroscopy,angle-resolved photoemission spectroscopy and first-principle calculations.Monolayer AgAs synthesized on Ag(111)provides a platform to study the physical properties of strained 2 D materials. 展开更多
关键词 materials. STRAINED SILVER
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铅锌冶炼污酸渣中重金属溶出研究
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作者 钱凯 郑诗礼 +5 位作者 张盈 周宏明 焦芬 陈世民 乔珊 邹兴 《过程工程学报》 CAS CSCD 北大核心 2024年第1期58-70,共13页
铅锌冶炼行业产生的重金属污酸渣对环境风险大,但同时也是一种可利用资源,硫酸钙基体净化是其资源化利用的第一步。本工作对污酸渣开展了全面的矿相解析,获得了污酸渣中重金属与硫酸钙的嵌布规律,并系统研究了加热时间、加热温度及硫酸... 铅锌冶炼行业产生的重金属污酸渣对环境风险大,但同时也是一种可利用资源,硫酸钙基体净化是其资源化利用的第一步。本工作对污酸渣开展了全面的矿相解析,获得了污酸渣中重金属与硫酸钙的嵌布规律,并系统研究了加热时间、加热温度及硫酸浓度对污酸渣中Fe, Zn, As, Pb, Cd, Sb等关键元素浸出率的影响,系统探究了这些元素在酸性介质中的溶出规律,且基于硫酸钙晶相与介质水活度、温度的一般规律,开展了硫酸介质中常压下水活度调控致相转和高温水热致相转对元素溶出的影响。结果表明,加热时间为2 h、加热温度为80℃及硫酸浓度为.01 mol/L时效果较为理想,且在此优化溶出条件下,污酸渣中As, Zn, Sb, Cd, Fe的浸出率均可达95%以上,浸出残渣为表面光滑的薄片状和棒状的二水硫酸钙晶相;降低介质中水的活度和水热条件能够促进硫酸钙的相转,借助硫酸钙形态或晶型的转化,可进一步强化硫酸钙晶格内或晶间重金属的溶出。基于硫酸钙转晶的金属强化溶出技术是硫酸钙渣基体深度净化的有效手段。 展开更多
关键词 冶炼污酸渣 硫酸介质 重金属溶出 硫酸钙相转
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N:ZnO/MoS_(2)-heterostructured flexible synaptic devices enabling optoelectronic co-modulation for robust artificial visual systems
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作者 Lei Xu Wenxiao Wang +6 位作者 Yang Li Yonghui Lin Wenjing Yue kai qian Qinglei Guo Jeonghyun Kim Guozhen Shen 《Nano Research》 SCIE EI CSCD 2024年第3期1902-1912,共11页
With the merits of non-contact,highly efficient,and parallel computing,optoelectronic synaptic devices combining sensing and memory in a single unit are promising for constructing neuromorphic computing and artificial... With the merits of non-contact,highly efficient,and parallel computing,optoelectronic synaptic devices combining sensing and memory in a single unit are promising for constructing neuromorphic computing and artificial visual chip.Based on this,a N:ZnO/MoS_(2)-heterostructured flexible optoelectronic synaptic device is developed in this work,and its capability in mimicking the synaptic behaviors is systemically investigated under the electrical and light signals.Versatile synaptic functions,including synaptic plasticity,long-term/short-term memory,and learning-forgetting-relearning property,have been achieved in this synaptic device.Further,an artificial visual memory system integrating sense and memory is emulated with the device array,and the visual memory behavior can be regulated by varying the light parameters.Moreover,the optoelectronic co-modulation behavior is verified by applying mixed electric and light signals to the array.In detail,a transient recovery property is discovered when the electric signals are applied in synergy during the decay of the light response,of which property facilitates the development of robust artificial visual systems.Furthermore,by superimposing electrical signals during the light response process,a differentiated response of the array is achieved,which can be used as a proof of concept for the color perception of the artificial visual system. 展开更多
关键词 flexible synaptic device synaptic plasticity optoelectronic synapse robust visual memory optoelectronic co-modulation artificial visual system
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Adaptor protein APPL1 links neuronal activity to chromatin remodeling in cultured hippocampal neurons 被引量:1
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作者 Yu Wu Xinyou Lv +8 位作者 Haiting Wang kai qian Jinjun Ding Jiejie Wang Shushan Hua Tiancheng Sun Yiting Zhou Lina Yu Shuang Qiu 《Journal of Molecular Cell Biology》 SCIE CAS CSCD 2021年第5期335-346,共12页
Local signaling events at synapses or axon terminals are communicated to the nucleus to elicit transcriptional responses,and thereby translate information about the external environment into internal neuronal represen... Local signaling events at synapses or axon terminals are communicated to the nucleus to elicit transcriptional responses,and thereby translate information about the external environment into internal neuronal representations.This retrograde signaling is critical to dendritic growth,synapse development,and neuronal plasticity.Here,we demonstrate that neuronal activity induces retrograde translocation and nuclear accumulation of endosomal adaptor APPL1.Disrupting the interaction of APPL1 with Importin ocl abolishes nuclear accumulation of APPL1,which in turn decreases the levels of histone acetylation.We further demonstrate that retrograde translocation of APPL1 is required for the regulation of gene transcription and then maintenance of hippocampal late-phase long-term potentiation.Thus,these results illustrate an APPLl-mediated pathway that contributes to the modulation of synaptic plasticity via coupling neuronal activity with chromatin remodeling. 展开更多
关键词 APPL1 excitation-transcription coupling synaptic plasticity chromatin remodeling gene transcription
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Measurement and analysis of content diffusion characteristics in opportunity environments with Spark
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作者 Xiao-hong ZHANG kai qian +3 位作者 Jian-ji REN Zong-pu JIA Tian-peng JIANG Quan ZHANG 《Frontiers of Information Technology & Electronic Engineering》 SCIE EI CSCD 2019年第10期1404-1414,共11页
Opportunity networks provide a chance to offload the tremendous cellular traffic generated by sharing popular content on mobile networks. Analyzing the content spread characteristics in real opportunity environments c... Opportunity networks provide a chance to offload the tremendous cellular traffic generated by sharing popular content on mobile networks. Analyzing the content spread characteristics in real opportunity environments can discover important clues for traffic offloading decision making. However, relevant published work is very limited since it is not easy to collect data from real environments. In this study, we elaborate the analysis on the dataset collected from a real opportunity environment formed by the users of Xender, which is one of the leading mobile applications for content sharing. To discover content transmission characteristics, scale, speed, and type analyses are implemented on the dataset. The analysis results show that file transmission has obvious periodicity, that only a very small fraction of files spread widely, and that application files have much higher probability to be popular than other files. We also propose a solution to maximize file spread scales, which is very helpful for forecasting popular files. The experimental results verify the effectiveness and usefulness of our solution. 展开更多
关键词 CONTENT DISSEMINATION Device-to-device communication OPPORTUNITY network Linear THRESHOLD model
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The electronic and optical properties of amorphous silica with hydrogen defects by ab initio calculations
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作者 Dahua Ren Baoyan Xiang +2 位作者 Cheng Hu kai qian Xinlu Cheng 《Journal of Semiconductors》 EI CAS CSCD 2018年第4期14-19,共6页
Hydrogen can be trapped in the bulk materials in four forms:interstitial molecular H_2,interstitial atom H,O^-H^+(2Si=O–H)^+,Si-H^-(4Oˉ≡Si H)^-to affect the electronic and optical properties of amorphous silica.The... Hydrogen can be trapped in the bulk materials in four forms:interstitial molecular H_2,interstitial atom H,O^-H^+(2Si=O–H)^+,Si-H^-(4Oˉ≡Si H)^-to affect the electronic and optical properties of amorphous silica.Therefore,the electronic and optical properties of defect-free and hydrogen defects in amorphous silica were performed within the scheme of density functional theory.Initially,the negative charged states hydrogen defects introduced new defect level between the valence band top and conduction band bottom.However,the neutral and positive charged state hydrogen defects made both the valence band and conduction band transfer to the lower energy.Subsequently,the optical properties such as absorption spectra,conductivity and loss functions were analyzed.It is indicated that the negative hydrogen defects caused the absorption peak ranging from 0 to 2.0 e V while the positive states produced absorption peaks at lower energy and two strong absorption peaks arose at 6.9 and 9.0 e V.However,the neutral hydrogen defects just improved the intensity of absorption spectrum.This may give insights into understanding the mechanism of laser-induced damage for optical materials. 展开更多
关键词 光性质 INITIO 非结晶 氢能 电子 硅石 吸收光谱 计算
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MgO intercalation and crystallization between epitaxial graphene and Ru(0001)
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作者 Xue-Yan Wang Hui Guo +11 位作者 Jin-An Shi Yi Biao Yan Li Guang-Yuan Han Shuai Zhang kai qian Wu Zhou Xiao Lin Shi-Xuan Du Cheng-Min Shen Hong-Liang Lu Hong-Jun Gao 《Rare Metals》 SCIE EI CAS CSCD 2022年第1期304-310,共7页
Graphene on insulator is the foundation of its practical applications in electronic information technology.However,fabrication of graphene on insulating substrates suffers from small size and limited quality by direct... Graphene on insulator is the foundation of its practical applications in electronic information technology.However,fabrication of graphene on insulating substrates suffers from small size and limited quality by direct growth of graphene on dielectric substrates,and the method of transferring graphene onto insulating substrates is not so compatible with the large-scale production in industry.Here,we report the fabrication of high-quality,large-area,single-crystal graphene on crystalline magnesium oxide(MgO),which has a dielectric constant of 7–10.Magnesium and oxygen are intercalated at the interface of epitaxial graphene/Ru(0001)and form crystalline structure after high-temperature annealing.The graphene/MgO/Ru(0001)sample was characterized by low energy electron diffraction(LEED),scanning tunneling microscopy(STM),X-ray photoelectron spectroscopy(XPS),and scanning transmission electron microscopy(STEM).LEED pattern shows that the magnesium oxide displays crystalline structure,and STM studies show clearly that the top layer is graphene.STEM characterization of as-intercalated sample demonstrates that the MgO intercalation layer,with a thickness of up to 2.3 nm,has a crystal structure of rock salt MgO,and the out-of-plane crystal orientation is[001].Our work provides a new route for fabrication of graphene on high dielectric constant insulators,which may have potential applications in future electronics. 展开更多
关键词 CRYSTALLINE DIELECTRIC MAGNESIUM
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Ultra-high temperature tolerant flexible transparent electrode with embedded silver nanowires bundle micromesh for electrical heater
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作者 Bowen Sun Ruixue Xu +11 位作者 Xu Han Jing Xu Wang Hong Yimeng Xu Zhiwei Fu He Zhu Xin Sun Jiangxin Wang Peng Cui Jingjing Chang Jiaqing Xiong kai qian 《npj Flexible Electronics》 SCIE 2022年第1期489-497,共9页
To realize high performance flexible transparent electronics with extreme environmental adaptivity,Ag nanowires(Ag NWs)electrodes should simultaneously meet the requirements of high-temperature tolerance,chemical and ... To realize high performance flexible transparent electronics with extreme environmental adaptivity,Ag nanowires(Ag NWs)electrodes should simultaneously meet the requirements of high-temperature tolerance,chemical and mechanical robustness.Herein,a scalable Ag NWs bundle micro-meshes embedded in polyimide(Ag BMs/ePI)conducting film via a facile spray coating and transfer method is reported.Due to the synergistic effect of bundle micromesh and embedded architecture,the Ag BMs/ePI electrode exhibits high thermal stability(370℃ and 400℃ under ambient and nitrogen atmosphere conditions,respectively),low sheet resistance variation(<4%),good corrosion and deformation resistance.As an electrical heater,the Ag BMs/ePI can achieve~204℃ with the fast thermal response time of~8 s at 8 V,and exhibits good heating stability under bent condition.This work offers a promising platform for the emerging flexible transparent electronics to adapt extreme environments,especially for those devices which require high-temperature processing. 展开更多
关键词 NANOWIRES TRANSPARENT BUNDLE
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