We report the scalable fabrication of CdS/ZnS 1D/2D heterojunctions under ambient air conditions(i.e.,room temperature and atmospheric pressure)in which ZnS nanoparticles are anchored on the surface of CdS nanosheets....We report the scalable fabrication of CdS/ZnS 1D/2D heterojunctions under ambient air conditions(i.e.,room temperature and atmospheric pressure)in which ZnS nanoparticles are anchored on the surface of CdS nanosheets.The as-formed heterojunctions exhibit a significantly enhanced photocatalytic H_(2) evolution rate of 14.02 mmol h^(-1) g^(-1) when irradiated with visible light,which is~10 and 85 times higher than those of pristine CdS nanosheets and CdS nanoparticles,respectively,and superior to most of the CdS-based photocatalysts reported to date.Furthermore,they provide robust photocatalytic performance with demonstratable stability over 58 h,indicating their potential for practical applications.The formation of 1D/2D heterojunctions not only provides improved exposed active sites that respond to illumination but also provides a rapid pathway to generate photogenerated carriers for efficient separation and transfer through the matrix of single-crystalline CdS nanosheets.In addition,first-principles simulations demonstrate that the existence of rich Zn vacancies increases the energy level of the ZnS valence band maximum to construct type-II and Z-scheme mixed heterojunctions,which plays a critical role in suppressing the recombination of carriers with limited photocorrosion of CdS to enhance photocatalytic behavior.展开更多
DEAR EDITOR,The introduction of freshwater fish into areas outside their native range has impacted freshwater ecosystems worldwide.In China,the non-native Alligator gar(Atractosteus spatula)fish has attracted attentio...DEAR EDITOR,The introduction of freshwater fish into areas outside their native range has impacted freshwater ecosystems worldwide.In China,the non-native Alligator gar(Atractosteus spatula)fish has attracted attention due to its widespread occurrence and destructive effects on local fish populations,signaling a high potential of invasiveness.展开更多
Mannose,a different isomer of the hydroxyl group at the C-2 position of glucose,shares the same transport carrier protein with glucose to enter cells and participate in the regulation of glucose metabolism.It affects ...Mannose,a different isomer of the hydroxyl group at the C-2 position of glucose,shares the same transport carrier protein with glucose to enter cells and participate in the regulation of glucose metabolism.It affects cell growth,differentiation,and function and plays an active role in tumor immunity and inflammatory processes.This paper provides theoretical support for expanding the clinical applications of mannose by exploring its constitution,metabolic pathways,and role in regulating immune cell function and treating immunology-related diseases.展开更多
To overcome the large time-delay in measuring the hardness of mixed rubber, rheological parameters were used to predict the hardness. A novel Q-based model updating strategy was proposed as a universal platform to tra...To overcome the large time-delay in measuring the hardness of mixed rubber, rheological parameters were used to predict the hardness. A novel Q-based model updating strategy was proposed as a universal platform to track time-varying properties. Using a few selected support samples to update the model, the strategy could dramatically save the storage cost and overcome the adverse influence of low signal-to-noise ratio samples. Moreover, it could be applied to any statistical process monitoring system without drastic changes to them, which is practical for industrial practices. As examples, the Q-based strategy was integrated with three popular algorithms(partial least squares(PLS), recursive PLS(RPLS), and kernel PLS(KPLS)) to form novel regression ones, QPLS, QRPLS and QKPLS, respectively. The applications for predicting mixed rubber hardness on a large-scale tire plant in east China prove the theoretical considerations.展开更多
In order to improve the reliability of hydrogen sensor,a novel strategy for full range of hydrogen sensor fault detection and recovery is proposed in this paper. Three kinds of sensors are integrated to realize the me...In order to improve the reliability of hydrogen sensor,a novel strategy for full range of hydrogen sensor fault detection and recovery is proposed in this paper. Three kinds of sensors are integrated to realize the measurement for full range of hydrogen concentration based on relevance vector machine( RVM). Failure detection of hydrogen sensor is carried out by using the variance detection method. When a sensor fault is detected,the other fault-free sensors can recover the fault data in real-time by using RVM predictor accounting for the relevance of sensor data. Analysis,together with both simulated and experimental results,a full-range hydrogen detection and hydrogen sensor self-validating experiment is presented to demonstrate that the proposed strategy is superior at accuracy and runtime compared with the conventional methods. Results show that the proposed methodology provides a better solution to the full range of hydrogen detection and the reliability improvement of hydrogen sensor.展开更多
The sluggish kinetics for water oxidation is recognized as one of the major problems for the unsatisfied photoelectrochemical(PEC) performance. Herein, we developed a feasible strategy based on in-situ selective surfa...The sluggish kinetics for water oxidation is recognized as one of the major problems for the unsatisfied photoelectrochemical(PEC) performance. Herein, we developed a feasible strategy based on in-situ selective surface cation exchange, for activating surface water oxidation reactivity toward boosted PEC water oxidation of BiVO_(4) photoanodes with fundamentally improved surface charge transfer. The asconstructed Co/BiVO_(4) photoanodes exhibit 2.6 times increase in photocurrent density with superior stability, in comparison to those of pristine counterpart. Moreover, the faradaic efficiency of as-fabricated photoanode can be up to ~ 95% at 1.23 V(vs. RHE). The unique selective replacement of Bi by Co on the surface could modify the electronic structure of BiVO_(4) with reduced energy barrier of the deprotonation of OH^(+) to O, thus favoring the overall excellent PEC performance of Co/BiVO_(4) photoanode.展开更多
The rapid progress of research into inflammatory bowel disease(IBD)has resulted in increasingly more treatment options.Different options have different advantages and disadvantages,and the preferences of patients may ...The rapid progress of research into inflammatory bowel disease(IBD)has resulted in increasingly more treatment options.Different options have different advantages and disadvantages,and the preferences of patients may also differ.If patients can be invited to the formulation of medical decision-making,their compliance and satisfaction would be improved,thus possibly achieving better therapeutic results.The present review aims to summarize the current literature on shared decision-making(SDM)in the management of IBD,with the goal of promoting the application of SDM.展开更多
Global climate change has a significant effect on species,as environment conditions change,causing many species'distributions to shift.During the last three million years,the earth has experienced glacial oscillat...Global climate change has a significant effect on species,as environment conditions change,causing many species'distributions to shift.During the last three million years,the earth has experienced glacial oscillations,forcing some species to survive in ice-free refugia during glacial periods and then disperse postglacially.In this study,by assessing the potential distribution of Siberian Grouse(Falcipennis falcipennis),we used Global Circular Models and Representative Concentration Pathways to model their pattern of range changes during glacial oscillations and the potential impact of present global warming.We used 158 location records of Siberian Grouse to generate a full climate model using 19 bioclimate variables in MaxEnt.We discarded variables with a correlation coefficient larger than 0.8 and relatively lower modeling contributions between each pair of correlated variables.Using the remaining variables,we created a normally uncorrelated simple climate model to predict the possible distribution of Siberian Grouse from the most recent Ice Age to present and to 2070.Then we added geographical data and the human interference index to construct a multiple factor full model to evaluate which were important in explaining the distribution of Siberian Grouse.The Total Suitability Zone(P≥0.33)of Siberian Grouse is about 243,000km^(2) and the Maximum Suitability Zone(P≥0.66)is 36,000km^(2) and is confined to the Russian Far East.Potential habitat modeling suggested that annual precipitation,annual mean temperature,and the distance from lakes are the most explanatory variables for the current distribution of Siberian Grouse.The distribution center moved to the southeast during the Last Glacial Maximum and spread back to the northwest after the ice melted and temperatures rose.The total area range of Siberian Grouse experienced a dramatic loss during the Last Glacial Maximum.Global warming is presently forcing the Siberian Grouse to migrate northward with a contraction of its range.There is an urgent need to protect its habitat,because little of its Maximum Sustainable Zone is protected,although there are some large reserves in that area.展开更多
Purpose:The 5th Plenary Session of the 19th Communist Party of China(CPC)Central Committee clearly states that developing science and technology through self-reliance and self-strengthening provides the strategic unde...Purpose:The 5th Plenary Session of the 19th Communist Party of China(CPC)Central Committee clearly states that developing science and technology through self-reliance and self-strengthening provides the strategic underpinning for China’s development.Based on this background,this paper explores a metric model for assessing national scientific research strength through collaboration on research papers.Design/methodology/approach:We propose a novel metric model for assessing national scientific research strength,which sets two indicators,national scientific self-reliance(SR)and national academic contribution(CT),to reflect“self-reliance”and“self-strengthening”respectively.Taking the research papers in quantum technology as an example,this study analyzes the scientific research strength of various countries around the world,especially China in quantum technology.Findings:The results show that the research of quantum technology in China has always been relatively independent with fewer international collaboration papers and located in a more marginal position in cooperation networks.China’s academic contribution(CT)to global quantum technology research is increasing and has been greater than that of the United States in 2020.Combining the two indicators,CT and SR,China’s research strength in the quantum field closely follows the United States,and the United States is the most powerful with high research autonomy.Research limitations:This paper only reflects China’s scientific research strength in quantum technology from collaboration on research papers and doesn’t consider the segmentation of quantum technology and the industrial upstream and downstream aspects,which need further study.Practical implications:The model is helpful to better understand the national scientific research strength in a certain field from“self-reliance”and“self-strengthening”.ScienceOriginality/value:We propose a novel metric model to measure the national scientific research strength from the perspective of“self-reliance”and“self-strengthening”,which provides a solid basis for the assessment of the strength level of scientific research in countries/regions and institutions.展开更多
The Chinese Grouse(Tetrastes sewerzowi) and Hazel Grouse(T. bonasia) are sibling species that are well-adapted to harsh high-altitude and latitude habitats. In the current study, we sampled and sequenced 29 Chinese Gr...The Chinese Grouse(Tetrastes sewerzowi) and Hazel Grouse(T. bonasia) are sibling species that are well-adapted to harsh high-altitude and latitude habitats. In the current study, we sampled and sequenced 29 Chinese Grouse(n=16) and Hazel Grouse(n=13) from eight locations in China, Sweden,Germany, and northeast Poland to analyze population genetic diversity and structure, introgression, and local adaptation.展开更多
As a thermosetting resin with excellent properties,epoxy resin is used in many areas such as electronics,transportation,aerospace,and other fields.However,its relatively low thermal conductivity limits its wide applic...As a thermosetting resin with excellent properties,epoxy resin is used in many areas such as electronics,transportation,aerospace,and other fields.However,its relatively low thermal conductivity limits its wide application in more demanding fields.Here,a three-dimensional carbon(3DC)network was prepared through NaCl template-assisted in situ chemical vapor deposition(CVD)and used to reinforce epoxy resin for enhancing its thermal conductivity.The 3DC was prepared with a molar ratio of sodium atom to carbon atom of 100:20,and argon atmosphere in CVD led to an optimal improvement in the thermal conductivity of epoxy resin.The thermal conductivity of epoxy resin increased by 18%when the filling content was 3 wt.%of 3DC network because of the high contact area,uniform dispersion,and enhanced formation of conductive paths with epoxy resin.As the amount of 3DC addition increases,the thermal conductivity of composites also increases.As an innovative exploration,the work presented in this paper is of great significance for the thermal conductivity application of epoxy resin in the future.展开更多
Objective:To evaluate the effect of existing acupuncture-related therapies on the longterm effects of post-stroke depression(PSD)by using a network meta-analysis with SSRIs as a common reference.Methods:The published ...Objective:To evaluate the effect of existing acupuncture-related therapies on the longterm effects of post-stroke depression(PSD)by using a network meta-analysis with SSRIs as a common reference.Methods:The published randomized controlled clinical trials of acupuncture-related therapies and SSRIs for PSD in PubMed,The Cochrane Library,EMbase,CNKI,CBM,VIP and wan-fang databases were comprehensively searched.The literature retrieval period was from The database establishment to July 31,2020.Cochrane Handbook 5.1.0 was used to assess the risk of bias in included studies.Data analysis is conducted through ADDIS,Review Manager 5.3,and STATA 13.1 software.Results:A total of 3115 patients with PSD were included in 30 RCTs,involving 10 therapeutic methods.Results of network meta-analysis showed that:in terms of total effective rate,body acupuncture+SSRIs was superior to body acupuncture[OR=2.85,95%CI(1.51,5.90)]and SSRIs[OR=5.37,95%CI(3.03,10.33)].In terms of HAMD score,body acupuncture+SSRIs was superior to body acupuncture[MD=1.69,95%CI(0.33,3.06)]and SSRIs[MD=3.87,95%CI(2.68,5.08)].The above ranking predicted that moxibustion+SSRIs was the best.In terms of NIHSS score,body acupuncture[MD=2.15,95%CI(1.10,3.26)]and body acupuncture+SSRIs[MD=1.77,95%CI(0.19,3.37)]were better than SSRIs.Conclusion:Moxibustion combined with SSRIs is the best for the long-term efficacy of acupuncture and moxibustion on PSD.Body acupuncture combined with SSRIs is better than SSRIs alone.The other therapies have their own advantages and disadvantages.Based on the defects of existing studies,this conclusion still needs to be verified by more high-quality RCTs.展开更多
Intensive aquaculture-induced oxidative stress is detrimental to fish health and yield.Medicinal plants show promise as natural health boosters and antioxidants in the aquaculture industry.Therefore,this work investig...Intensive aquaculture-induced oxidative stress is detrimental to fish health and yield.Medicinal plants show promise as natural health boosters and antioxidants in the aquaculture industry.Therefore,this work investigated the effects of turmeric aqueous extract(TAE)on the growth performance,antioxidant status,and hydrogen peroxide(H2O2)-induced oxidative stress in spotted seabass(Lateolabrax maculatus).Fish were fed diets supplemented with 0(Con),2(TAE2),or 4(TAE4)g/kg TAE for eight weeks,then were injected with H2O2.The results showed that dietary supplementation of TAE did not affect fish growth,feed utilization,or body composition.TAE treatment increased liver antioxidant enzyme activities and decreased liver malondialdehyde content and serum levels of glutamate oxalate transaminase,glutamate pyruvate transaminase,and lactate dehydrogenase.Furthermore,the increases in mortality,liver malondialdehyde content,and serum biomarkers of liver injury in the H2O2-treated fish were inhibited as a consequence of the TAE treatment.In addition,TAE treatment activated the Nrf2/Keap1 pathway in the liver,supported by the up-regulated expression of nrf2,ho-1,and gclc,and down-regulated keap1 expression.Overall,dietary incorporation of TAE protected against H2O2-induced oxidative stress in spotted seabass probably by enhancing antioxidant capacity through the Nrf2/Keap1 pathway.展开更多
Silk is one of the toughest fibrous materials known despite spun at ambient temperature and pressure with water as a solvent.It is a great challenge to reproduce high-performance artificial fibers comparable to natura...Silk is one of the toughest fibrous materials known despite spun at ambient temperature and pressure with water as a solvent.It is a great challenge to reproduce high-performance artificial fibers comparable to natural silk by bionic for the incomplete understanding of silkworm spinning in vivo.Here,we found that amphipol and digitonin stabilized the structure of natural silk fibroin(NSF)by a large-scale screening in vitro,and then studied the close-to-native ultrastructure and hierarchical assembly of NSF in the silk gland lumen.Our study showed that NSF formed reversible flexible nanofibrils mainly composed of random coils with a sedimentation coefficient of 5.8 S and a diameter of about 4 nm,rather than a micellar or rod-like structure assembled by the aggregation of globular NSF molecules.Metal ions were required for NSF nanofibril formation.The successive p H decrease from posterior silk gland(PSG)to anterior silk gland(ASG)resulted in a gradual increase in NSF hydrophobicity,thus inducing the sol-gelation transition of NSF nanofibrils.NSF nanofibrils were randomly dispersed from PSG to ASG-1,and self-assembled into anisotropic herringbone patterns at ASG-2 near the spinneret ready for silkworm spinning.Our findings reveal the controlled self-assembly mechanism of the multi-scale hierarchical architecture of NSF from nanofibrils to herringbone patterns programmed by metal ions and p H gradient,which provides novel insights into the spinning mechanism of silk-secreting animals and bioinspired design of high-performance fibers.展开更多
The oil-gas two-phase hybrid transportation technology is one of the innovative technology directions for the exploitation and transportation of marginal and deep ocean oilfields.The helical-axial multiphase pump is a...The oil-gas two-phase hybrid transportation technology is one of the innovative technology directions for the exploitation and transportation of marginal and deep ocean oilfields.The helical-axial multiphase pump is a key equipment for oil and gas extraction.At this stage,most of the research on this kind of pump focuses on the improvement of the structure and conveying performance.However,because of insufficient understanding of the flow behavior and mechanism of bubbles,it is easy to cause the gas-liquid separation.In this paper,the numerical simulation and test are combined to explore the changes in the bubble trajectory and flow structure of the helical-axial multiphase pump.The results shown that when the speed is lower than 1200 r/min,the bubble reaches the maximum volume at 1/2 of the midline of the impeller blade and it contact with the pressure surface,broken to the suction surface.When the rotation speed is higher than 1450 r/min,the number of bubbles in the impeller increases and the size decreases.The backflow occurs in the tip clearance and strength increases continuously.The research results have important significance for the theoretical design and engineering application of the helical-axial multiphase pump.展开更多
Objective: Electroacupuncture (EA) in the treating principle of “soothing the liver and regulating the kidney” was applied to intervion the rats with post-traumatic stress disorder (PTSD), and its effect on anxiety-...Objective: Electroacupuncture (EA) in the treating principle of “soothing the liver and regulating the kidney” was applied to intervion the rats with post-traumatic stress disorder (PTSD), and its effect on anxiety-like behavior, spatial learning and memory ability, and expressions of synaptophysin (SYN) and postsynaptic dense 95 (PSD95) in hippocampus of rats were observed to explore the underlying mechanism.Methods: Twenty-four male SD rats were randomly divided into control group, model group, and EA group, with 8 rats in each group. There was no intervention in the control group. The rest 16 rats were prepared for modeling. The single-prolonged stress & shock (SPS&S) method was used to establish the PTSD models. There was no intervention in the model group after modeling. In the EA group, “Bǎihuì (百会GV20)”“ Shéntíng (神庭GV24)”“Gānshū (肝俞BL18)”“Shènshū (肾俞BL23)” were manipulated with EA stimulation, intensity 1 mA, frequency 2/100 Hz, disperse-dense wave, and treatment was performed once a day, 20 min each time, for a total of 21 days. Open field test, elevated plus maze and Morris water maze tests were used to observe the behavioral differences of rats in each group. Immunohistochemical method was used to observe the differences of positive expressions of proteins SYN and PSD95 in hippocampus.Results: In the open field test, compared with the control group, the total traveling distance, the percentage of the time spent in the central cell and the numbers of the central cells crossing in the model group were all decreased (all P < 0.05). Compared with the model group, these indicators in the EA group were significantly all increased (all P < 0.05). In the elevated plus maze test, compared with the control group, the percentages of open arm staying time and entering times in the model group were both decreased (both P < 0.05). Compared with the model group, these indicators in the EA group were both significantly increased (both P < 0.05). The results of Morris water maze test showed that compared with the control group, the escape latency time and travelled distance of rats in the model group were all increased from day1 to day 4 (all P < 0.05), and the percentage of staying time in the target quadrant was decreased (P < 0.05). Compared with the model group, the escape latency time and travelled distance of EA group were both significantly shortened (both P < 0.05), and the percentage of staying time in the target quadrant was significantly increased (P < 0.05). The immunohistochemical results showed that, compared with the control group, the positive expressions of SYN and PSD95 in the hippocampus of the model group were significantly down-regulated (both P < 0.05). Compared with the model group, the positive expressions of SYN and PSD95 in the hippocampus of the EA group were significantly up-regulated (both P < 0.05).Conclusions: EA in the treating principle of “soothing the liver and regulating the kidney” can effectively relieve anxiety-like behavior and improve spatial learning and memory ability of rats with PTSD, and the mechanism is related to the up-regulation of the expressions of SYN and PSD95 in the hippocampus.展开更多
Oxygen reduction reaction(ORR)plays an important role in the next-generation energy storage technologies,whereas it involves the sluggish and complicated proton-coupled electron transfer(PCET)steps that greatly limit ...Oxygen reduction reaction(ORR)plays an important role in the next-generation energy storage technologies,whereas it involves the sluggish and complicated proton-coupled electron transfer(PCET)steps that greatly limit the ORR kinetics.Therefore,it is urgent to construct an efficient catalyst that could simultaneously achieve the rapid oxygen-containing intermediates conversion and fast PCET process but remain challenging.Herein,the adjacent Fe_(3)C nanoparticles coupling with single Fe sites on the bubble-wrap-like porous N-doped carbon(Fe_(3)C@FeSA-NC)were deliberately constructed.Theoretical investigations reveal that the adjacent Fe_(3)C nanoparticles speed up the water dissociation and serve as proton-feeding centers for boosting the ORR kinetics of single Fe sites.Benefiting from the synergistic effect of the Fe_(3)C and single Fe sites,the Fe_(3)C@FeSA-NC affords an excellent half-wave potential of 0.88 V,and enables the assembled Zn-air batteries with the high peak power density of 164.5 mW·cm^(-2)and long-term stability of over 200 h at high current densities at 50 mA·cm^(-2).This work clarifies the mechanism for improving ORR kinetics of single atomic sites by engineering the adjacent proton-feeding centers,shedding light on the rational design of cost-effective electrocatalysts for energy conversion and storage technologies.展开更多
基金Hunan Provincial Innovation Foundation for Postgraduate,Grant/Award Number:CX20200454National Natural Science Foundation of China,Grant/Award Number:51972178。
文摘We report the scalable fabrication of CdS/ZnS 1D/2D heterojunctions under ambient air conditions(i.e.,room temperature and atmospheric pressure)in which ZnS nanoparticles are anchored on the surface of CdS nanosheets.The as-formed heterojunctions exhibit a significantly enhanced photocatalytic H_(2) evolution rate of 14.02 mmol h^(-1) g^(-1) when irradiated with visible light,which is~10 and 85 times higher than those of pristine CdS nanosheets and CdS nanoparticles,respectively,and superior to most of the CdS-based photocatalysts reported to date.Furthermore,they provide robust photocatalytic performance with demonstratable stability over 58 h,indicating their potential for practical applications.The formation of 1D/2D heterojunctions not only provides improved exposed active sites that respond to illumination but also provides a rapid pathway to generate photogenerated carriers for efficient separation and transfer through the matrix of single-crystalline CdS nanosheets.In addition,first-principles simulations demonstrate that the existence of rich Zn vacancies increases the energy level of the ZnS valence band maximum to construct type-II and Z-scheme mixed heterojunctions,which plays a critical role in suppressing the recombination of carriers with limited photocorrosion of CdS to enhance photocatalytic behavior.
基金supported by the National Natural Science Foundation of China(32022009)。
文摘DEAR EDITOR,The introduction of freshwater fish into areas outside their native range has impacted freshwater ecosystems worldwide.In China,the non-native Alligator gar(Atractosteus spatula)fish has attracted attention due to its widespread occurrence and destructive effects on local fish populations,signaling a high potential of invasiveness.
基金supported by Natural Science Foundation Project of Jilin Provincial Department of Science and Technology(YDZJ202301ZYTS348)。
文摘Mannose,a different isomer of the hydroxyl group at the C-2 position of glucose,shares the same transport carrier protein with glucose to enter cells and participate in the regulation of glucose metabolism.It affects cell growth,differentiation,and function and plays an active role in tumor immunity and inflammatory processes.This paper provides theoretical support for expanding the clinical applications of mannose by exploring its constitution,metabolic pathways,and role in regulating immune cell function and treating immunology-related diseases.
基金supported by the National Natural Science Foundation of China(No.21673246)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB12020300)
文摘To overcome the large time-delay in measuring the hardness of mixed rubber, rheological parameters were used to predict the hardness. A novel Q-based model updating strategy was proposed as a universal platform to track time-varying properties. Using a few selected support samples to update the model, the strategy could dramatically save the storage cost and overcome the adverse influence of low signal-to-noise ratio samples. Moreover, it could be applied to any statistical process monitoring system without drastic changes to them, which is practical for industrial practices. As examples, the Q-based strategy was integrated with three popular algorithms(partial least squares(PLS), recursive PLS(RPLS), and kernel PLS(KPLS)) to form novel regression ones, QPLS, QRPLS and QKPLS, respectively. The applications for predicting mixed rubber hardness on a large-scale tire plant in east China prove the theoretical considerations.
基金Sponsored by the National Natural Science Foundation of China(Grant No.61201306 and No.61473095)
文摘In order to improve the reliability of hydrogen sensor,a novel strategy for full range of hydrogen sensor fault detection and recovery is proposed in this paper. Three kinds of sensors are integrated to realize the measurement for full range of hydrogen concentration based on relevance vector machine( RVM). Failure detection of hydrogen sensor is carried out by using the variance detection method. When a sensor fault is detected,the other fault-free sensors can recover the fault data in real-time by using RVM predictor accounting for the relevance of sensor data. Analysis,together with both simulated and experimental results,a full-range hydrogen detection and hydrogen sensor self-validating experiment is presented to demonstrate that the proposed strategy is superior at accuracy and runtime compared with the conventional methods. Results show that the proposed methodology provides a better solution to the full range of hydrogen detection and the reliability improvement of hydrogen sensor.
基金supported by the project funded by the National Natural Science Foundation of China (52172222, 5197226 and 51972178)the China Postdoctoral Science Foundation(2020 M681966)+1 种基金the exchange project of the sixth ChinaNorthern Macedonia Science and Technology Meeting (6-11)the Natural Science Foundation of Ningbo Municipal Government(202003 N4164 and 2021J145)。
文摘The sluggish kinetics for water oxidation is recognized as one of the major problems for the unsatisfied photoelectrochemical(PEC) performance. Herein, we developed a feasible strategy based on in-situ selective surface cation exchange, for activating surface water oxidation reactivity toward boosted PEC water oxidation of BiVO_(4) photoanodes with fundamentally improved surface charge transfer. The asconstructed Co/BiVO_(4) photoanodes exhibit 2.6 times increase in photocurrent density with superior stability, in comparison to those of pristine counterpart. Moreover, the faradaic efficiency of as-fabricated photoanode can be up to ~ 95% at 1.23 V(vs. RHE). The unique selective replacement of Bi by Co on the surface could modify the electronic structure of BiVO_(4) with reduced energy barrier of the deprotonation of OH^(+) to O, thus favoring the overall excellent PEC performance of Co/BiVO_(4) photoanode.
基金Supported by Peking Union Medical College,No.2019zlgc0503.
文摘The rapid progress of research into inflammatory bowel disease(IBD)has resulted in increasingly more treatment options.Different options have different advantages and disadvantages,and the preferences of patients may also differ.If patients can be invited to the formulation of medical decision-making,their compliance and satisfaction would be improved,thus possibly achieving better therapeutic results.The present review aims to summarize the current literature on shared decision-making(SDM)in the management of IBD,with the goal of promoting the application of SDM.
基金funded by National Natural Science Foundation of China and Russian Foundation for Basic Research (NSFC-RFBR:32011530077 to YHS)
文摘Global climate change has a significant effect on species,as environment conditions change,causing many species'distributions to shift.During the last three million years,the earth has experienced glacial oscillations,forcing some species to survive in ice-free refugia during glacial periods and then disperse postglacially.In this study,by assessing the potential distribution of Siberian Grouse(Falcipennis falcipennis),we used Global Circular Models and Representative Concentration Pathways to model their pattern of range changes during glacial oscillations and the potential impact of present global warming.We used 158 location records of Siberian Grouse to generate a full climate model using 19 bioclimate variables in MaxEnt.We discarded variables with a correlation coefficient larger than 0.8 and relatively lower modeling contributions between each pair of correlated variables.Using the remaining variables,we created a normally uncorrelated simple climate model to predict the possible distribution of Siberian Grouse from the most recent Ice Age to present and to 2070.Then we added geographical data and the human interference index to construct a multiple factor full model to evaluate which were important in explaining the distribution of Siberian Grouse.The Total Suitability Zone(P≥0.33)of Siberian Grouse is about 243,000km^(2) and the Maximum Suitability Zone(P≥0.66)is 36,000km^(2) and is confined to the Russian Far East.Potential habitat modeling suggested that annual precipitation,annual mean temperature,and the distance from lakes are the most explanatory variables for the current distribution of Siberian Grouse.The distribution center moved to the southeast during the Last Glacial Maximum and spread back to the northwest after the ice melted and temperatures rose.The total area range of Siberian Grouse experienced a dramatic loss during the Last Glacial Maximum.Global warming is presently forcing the Siberian Grouse to migrate northward with a contraction of its range.There is an urgent need to protect its habitat,because little of its Maximum Sustainable Zone is protected,although there are some large reserves in that area.
基金supported by National Key R&D Program of China(Grant No.2019YFA0707201)the open fund of ISTIC-Springer Nature Joint Lab for Open Science(Grant No.HX20211292).
文摘Purpose:The 5th Plenary Session of the 19th Communist Party of China(CPC)Central Committee clearly states that developing science and technology through self-reliance and self-strengthening provides the strategic underpinning for China’s development.Based on this background,this paper explores a metric model for assessing national scientific research strength through collaboration on research papers.Design/methodology/approach:We propose a novel metric model for assessing national scientific research strength,which sets two indicators,national scientific self-reliance(SR)and national academic contribution(CT),to reflect“self-reliance”and“self-strengthening”respectively.Taking the research papers in quantum technology as an example,this study analyzes the scientific research strength of various countries around the world,especially China in quantum technology.Findings:The results show that the research of quantum technology in China has always been relatively independent with fewer international collaboration papers and located in a more marginal position in cooperation networks.China’s academic contribution(CT)to global quantum technology research is increasing and has been greater than that of the United States in 2020.Combining the two indicators,CT and SR,China’s research strength in the quantum field closely follows the United States,and the United States is the most powerful with high research autonomy.Research limitations:This paper only reflects China’s scientific research strength in quantum technology from collaboration on research papers and doesn’t consider the segmentation of quantum technology and the industrial upstream and downstream aspects,which need further study.Practical implications:The model is helpful to better understand the national scientific research strength in a certain field from“self-reliance”and“self-strengthening”.ScienceOriginality/value:We propose a novel metric model to measure the national scientific research strength from the perspective of“self-reliance”and“self-strengthening”,which provides a solid basis for the assessment of the strength level of scientific research in countries/regions and institutions.
基金supported by the National Natural Science Foundation of China(31520103903)。
文摘The Chinese Grouse(Tetrastes sewerzowi) and Hazel Grouse(T. bonasia) are sibling species that are well-adapted to harsh high-altitude and latitude habitats. In the current study, we sampled and sequenced 29 Chinese Grouse(n=16) and Hazel Grouse(n=13) from eight locations in China, Sweden,Germany, and northeast Poland to analyze population genetic diversity and structure, introgression, and local adaptation.
基金the Key Projects of Tianjin Natural Science Foundation(No.16ZXCLGX00130).
文摘As a thermosetting resin with excellent properties,epoxy resin is used in many areas such as electronics,transportation,aerospace,and other fields.However,its relatively low thermal conductivity limits its wide application in more demanding fields.Here,a three-dimensional carbon(3DC)network was prepared through NaCl template-assisted in situ chemical vapor deposition(CVD)and used to reinforce epoxy resin for enhancing its thermal conductivity.The 3DC was prepared with a molar ratio of sodium atom to carbon atom of 100:20,and argon atmosphere in CVD led to an optimal improvement in the thermal conductivity of epoxy resin.The thermal conductivity of epoxy resin increased by 18%when the filling content was 3 wt.%of 3DC network because of the high contact area,uniform dispersion,and enhanced formation of conductive paths with epoxy resin.As the amount of 3DC addition increases,the thermal conductivity of composites also increases.As an innovative exploration,the work presented in this paper is of great significance for the thermal conductivity application of epoxy resin in the future.
基金National Natural Science Foundation of China(No.81873384)。
文摘Objective:To evaluate the effect of existing acupuncture-related therapies on the longterm effects of post-stroke depression(PSD)by using a network meta-analysis with SSRIs as a common reference.Methods:The published randomized controlled clinical trials of acupuncture-related therapies and SSRIs for PSD in PubMed,The Cochrane Library,EMbase,CNKI,CBM,VIP and wan-fang databases were comprehensively searched.The literature retrieval period was from The database establishment to July 31,2020.Cochrane Handbook 5.1.0 was used to assess the risk of bias in included studies.Data analysis is conducted through ADDIS,Review Manager 5.3,and STATA 13.1 software.Results:A total of 3115 patients with PSD were included in 30 RCTs,involving 10 therapeutic methods.Results of network meta-analysis showed that:in terms of total effective rate,body acupuncture+SSRIs was superior to body acupuncture[OR=2.85,95%CI(1.51,5.90)]and SSRIs[OR=5.37,95%CI(3.03,10.33)].In terms of HAMD score,body acupuncture+SSRIs was superior to body acupuncture[MD=1.69,95%CI(0.33,3.06)]and SSRIs[MD=3.87,95%CI(2.68,5.08)].The above ranking predicted that moxibustion+SSRIs was the best.In terms of NIHSS score,body acupuncture[MD=2.15,95%CI(1.10,3.26)]and body acupuncture+SSRIs[MD=1.77,95%CI(0.19,3.37)]were better than SSRIs.Conclusion:Moxibustion combined with SSRIs is the best for the long-term efficacy of acupuncture and moxibustion on PSD.Body acupuncture combined with SSRIs is better than SSRIs alone.The other therapies have their own advantages and disadvantages.Based on the defects of existing studies,this conclusion still needs to be verified by more high-quality RCTs.
基金the National Natural Science Foundation of China，the National Basic Research Program，the Strategic Priority Research Program of Chinese Academy of Sciences
基金supported by China Agriculture Research System (CARS-47)the Natural Science Foundation of Fujian Province of China (grant number:2019J01060380).
文摘Intensive aquaculture-induced oxidative stress is detrimental to fish health and yield.Medicinal plants show promise as natural health boosters and antioxidants in the aquaculture industry.Therefore,this work investigated the effects of turmeric aqueous extract(TAE)on the growth performance,antioxidant status,and hydrogen peroxide(H2O2)-induced oxidative stress in spotted seabass(Lateolabrax maculatus).Fish were fed diets supplemented with 0(Con),2(TAE2),or 4(TAE4)g/kg TAE for eight weeks,then were injected with H2O2.The results showed that dietary supplementation of TAE did not affect fish growth,feed utilization,or body composition.TAE treatment increased liver antioxidant enzyme activities and decreased liver malondialdehyde content and serum levels of glutamate oxalate transaminase,glutamate pyruvate transaminase,and lactate dehydrogenase.Furthermore,the increases in mortality,liver malondialdehyde content,and serum biomarkers of liver injury in the H2O2-treated fish were inhibited as a consequence of the TAE treatment.In addition,TAE treatment activated the Nrf2/Keap1 pathway in the liver,supported by the up-regulated expression of nrf2,ho-1,and gclc,and down-regulated keap1 expression.Overall,dietary incorporation of TAE protected against H2O2-induced oxidative stress in spotted seabass probably by enhancing antioxidant capacity through the Nrf2/Keap1 pathway.
基金supported by the National Key Research and Development Program of China(2022YFD1201600,2021YFA1300100,and 2018YFE0203300)the National Natural Science Foundation of China(31972622 and 32241029)+6 种基金the State Key Program of National Natural Science Foundation of China(32030103)the Natural Science Foundation of Chongqing,China(CSTB2022NSCQ-LZX0302,CSTB2022NSCQ-MSX0761,and cstc2020jcyj-cxtt X0001)the Fundamental Research Funds for the Central Universities(XDJK2020TJ001)the Key Project of Science and Technology Research Program of Chongqing Municipal Education Commission,China(KJZD-K202200205)the Chinese Academy of Sciences(CAS)Strategic Priority Research Program(XDB37010100)the Shennong Youth Talent Program(Ministry of Agriculture and Rural Affairs,China)the Chongqing Innovation Supporting Program for Oversea Returned Talents(CX2023069)。
文摘Silk is one of the toughest fibrous materials known despite spun at ambient temperature and pressure with water as a solvent.It is a great challenge to reproduce high-performance artificial fibers comparable to natural silk by bionic for the incomplete understanding of silkworm spinning in vivo.Here,we found that amphipol and digitonin stabilized the structure of natural silk fibroin(NSF)by a large-scale screening in vitro,and then studied the close-to-native ultrastructure and hierarchical assembly of NSF in the silk gland lumen.Our study showed that NSF formed reversible flexible nanofibrils mainly composed of random coils with a sedimentation coefficient of 5.8 S and a diameter of about 4 nm,rather than a micellar or rod-like structure assembled by the aggregation of globular NSF molecules.Metal ions were required for NSF nanofibril formation.The successive p H decrease from posterior silk gland(PSG)to anterior silk gland(ASG)resulted in a gradual increase in NSF hydrophobicity,thus inducing the sol-gelation transition of NSF nanofibrils.NSF nanofibrils were randomly dispersed from PSG to ASG-1,and self-assembled into anisotropic herringbone patterns at ASG-2 near the spinneret ready for silkworm spinning.Our findings reveal the controlled self-assembly mechanism of the multi-scale hierarchical architecture of NSF from nanofibrils to herringbone patterns programmed by metal ions and p H gradient,which provides novel insights into the spinning mechanism of silk-secreting animals and bioinspired design of high-performance fibers.
基金supported by the National Natural Science Foundation of China(Grant Nos.51969014,51609113)supported by the China Postdoctoral Science Foundation(Grant No.2018M633651XB)+2 种基金the Natural Science Foundation of Gansu(Grant No.20JR5RA456)the Outstanding Young Talents Funding Scheme of Gansu province(Grant No.20JR10RA204)the Hong liu Outstanding Young Talents Funding Schemeof Lanzhou University of Technology.
文摘The oil-gas two-phase hybrid transportation technology is one of the innovative technology directions for the exploitation and transportation of marginal and deep ocean oilfields.The helical-axial multiphase pump is a key equipment for oil and gas extraction.At this stage,most of the research on this kind of pump focuses on the improvement of the structure and conveying performance.However,because of insufficient understanding of the flow behavior and mechanism of bubbles,it is easy to cause the gas-liquid separation.In this paper,the numerical simulation and test are combined to explore the changes in the bubble trajectory and flow structure of the helical-axial multiphase pump.The results shown that when the speed is lower than 1200 r/min,the bubble reaches the maximum volume at 1/2 of the midline of the impeller blade and it contact with the pressure surface,broken to the suction surface.When the rotation speed is higher than 1450 r/min,the number of bubbles in the impeller increases and the size decreases.The backflow occurs in the tip clearance and strength increases continuously.The research results have important significance for the theoretical design and engineering application of the helical-axial multiphase pump.
基金Supported by National Natural Science Foundation of China:81873384。
文摘Objective: Electroacupuncture (EA) in the treating principle of “soothing the liver and regulating the kidney” was applied to intervion the rats with post-traumatic stress disorder (PTSD), and its effect on anxiety-like behavior, spatial learning and memory ability, and expressions of synaptophysin (SYN) and postsynaptic dense 95 (PSD95) in hippocampus of rats were observed to explore the underlying mechanism.Methods: Twenty-four male SD rats were randomly divided into control group, model group, and EA group, with 8 rats in each group. There was no intervention in the control group. The rest 16 rats were prepared for modeling. The single-prolonged stress & shock (SPS&S) method was used to establish the PTSD models. There was no intervention in the model group after modeling. In the EA group, “Bǎihuì (百会GV20)”“ Shéntíng (神庭GV24)”“Gānshū (肝俞BL18)”“Shènshū (肾俞BL23)” were manipulated with EA stimulation, intensity 1 mA, frequency 2/100 Hz, disperse-dense wave, and treatment was performed once a day, 20 min each time, for a total of 21 days. Open field test, elevated plus maze and Morris water maze tests were used to observe the behavioral differences of rats in each group. Immunohistochemical method was used to observe the differences of positive expressions of proteins SYN and PSD95 in hippocampus.Results: In the open field test, compared with the control group, the total traveling distance, the percentage of the time spent in the central cell and the numbers of the central cells crossing in the model group were all decreased (all P < 0.05). Compared with the model group, these indicators in the EA group were significantly all increased (all P < 0.05). In the elevated plus maze test, compared with the control group, the percentages of open arm staying time and entering times in the model group were both decreased (both P < 0.05). Compared with the model group, these indicators in the EA group were both significantly increased (both P < 0.05). The results of Morris water maze test showed that compared with the control group, the escape latency time and travelled distance of rats in the model group were all increased from day1 to day 4 (all P < 0.05), and the percentage of staying time in the target quadrant was decreased (P < 0.05). Compared with the model group, the escape latency time and travelled distance of EA group were both significantly shortened (both P < 0.05), and the percentage of staying time in the target quadrant was significantly increased (P < 0.05). The immunohistochemical results showed that, compared with the control group, the positive expressions of SYN and PSD95 in the hippocampus of the model group were significantly down-regulated (both P < 0.05). Compared with the model group, the positive expressions of SYN and PSD95 in the hippocampus of the EA group were significantly up-regulated (both P < 0.05).Conclusions: EA in the treating principle of “soothing the liver and regulating the kidney” can effectively relieve anxiety-like behavior and improve spatial learning and memory ability of rats with PTSD, and the mechanism is related to the up-regulation of the expressions of SYN and PSD95 in the hippocampus.
基金This work was financially supported by the National Natural Science Foundation of China(Nos.52261145700 and 22279124)the Natural Science Foundation of Shandong Province(No.ZR2020ZD10)the Fundamental Research Funds for the Central Universities(No.202262010).
文摘Oxygen reduction reaction(ORR)plays an important role in the next-generation energy storage technologies,whereas it involves the sluggish and complicated proton-coupled electron transfer(PCET)steps that greatly limit the ORR kinetics.Therefore,it is urgent to construct an efficient catalyst that could simultaneously achieve the rapid oxygen-containing intermediates conversion and fast PCET process but remain challenging.Herein,the adjacent Fe_(3)C nanoparticles coupling with single Fe sites on the bubble-wrap-like porous N-doped carbon(Fe_(3)C@FeSA-NC)were deliberately constructed.Theoretical investigations reveal that the adjacent Fe_(3)C nanoparticles speed up the water dissociation and serve as proton-feeding centers for boosting the ORR kinetics of single Fe sites.Benefiting from the synergistic effect of the Fe_(3)C and single Fe sites,the Fe_(3)C@FeSA-NC affords an excellent half-wave potential of 0.88 V,and enables the assembled Zn-air batteries with the high peak power density of 164.5 mW·cm^(-2)and long-term stability of over 200 h at high current densities at 50 mA·cm^(-2).This work clarifies the mechanism for improving ORR kinetics of single atomic sites by engineering the adjacent proton-feeding centers,shedding light on the rational design of cost-effective electrocatalysts for energy conversion and storage technologies.
