Neurological disorders exert significantly affect the quality of life for patients,necessitating effective strategies for nerve regeneration.Both traditional autologous nerve transplantation and emerging therapeutic a...Neurological disorders exert significantly affect the quality of life for patients,necessitating effective strategies for nerve regeneration.Both traditional autologous nerve transplantation and emerging therapeutic approaches encounter scientific challenges due to the complex nature of the nervous system and the unsuitability of the surrounding environment for cell transplantation.Tissue engineering techniques offer a promising path for neurotherapy.Successful neural tissue engineering relies on modulating cell differentiation behavior and tissue repair by developing biomaterials that mimic the natural extracellular matrix(ECM)and establish a threedimensional microenvironment.Peptide-based hydrogels have emerged as a potent option among these biomaterials due to their ability to replicate the structure and complexity of the ECM.This review aims to explore the diverse range of peptide-based hydrogels used in nerve regeneration with a specific focus on dipeptide hydrogels,tripeptide hydrogels,oligopeptide hydrogels,multidomain peptides(MDPs),and amphiphilic peptide hydrogels(PAs).Peptide-based hydrogels offer numerous advantages,including biocompatibility,structural diversity,adjustable mechanical properties,and degradation without adverse effects.Notably,hydrogels formed from self-assembled polypeptide nanofibers,derived from amino acids,show promising potential in engineering neural tissues,outperforming conventional materials like alginate,poly(ε-caprolactone),and polyaniline.Additionally,the simple design and cost-effectiveness of dipeptidebased hydrogels have enabled the creation of various functional supramolecular structures,with significant implications for nervous system regeneration.These hydrogels are expected to play a crucial role in future neural tissue engineering research.This review aims to highlight the benefits and potential applications of peptidebased hydrogels,contributing to the advancement of neural tissue engineering.展开更多
Multifunctional and flexible wearable devices play a crucial role in a wide range of applications,such as heath monitoring,intelligent skins,and human-machine interactions.Developing flexible and conductive materials ...Multifunctional and flexible wearable devices play a crucial role in a wide range of applications,such as heath monitoring,intelligent skins,and human-machine interactions.Developing flexible and conductive materials for multifunctional wearable devices with low-cost and high efficiency methods are highly desirable.Here,a conductive graphene/microsphere/bamboo fiber(GMB)nanocomposite paper with hierarchical surface microstructures is successfully fabricated through a simple vacuum-assisted filtration followed by thermo-foaming process.The as-prepared microstructured GMB nanocomposite paper exhibits not only a high volume electrical conductivity of~45 S/m but also an excellent electrical stability(i.e.,relative changes in resistance are less than 3%under stretching,folding,and compressing loadings)due to its unique structure features.With this microstructured nanocomposite paper as active sensing layer,microstructured pressure sensors with a high sensitivity(-4 kPa^(-1)),a wide sensing range(0–5 kPa),and a rapid response time(about 140 ms)are realized.In addition,benefitting from the outstanding electrical stability and mechanical flexibility,the microstructured nanocomposite paper is further demonstrated as a low-voltage Joule heating device.The surface temperature of the microstructured nanocomposite paper rapidly reaches over 80℃ when applying a relatively low voltage of 7 V,indicating its potential in human thermotherapy and thermal management.展开更多
Controllable synthesis of insertion-type anode materials with beneficial micro-and nanostructures is a promising approach for the synthesis of sodium-ion storage devices with high-reactivity and excellent electrochemi...Controllable synthesis of insertion-type anode materials with beneficial micro-and nanostructures is a promising approach for the synthesis of sodium-ion storage devices with high-reactivity and excellent electrochemical performance.In this study,we developed a sacrificial-templating route to synthesize TiO_(2)@N-doped carbon nanotubes(TiO_(2)@NC-NTs)with excellent electrochemical performance.The asprepared mesoporous TiO_(2)@NC-NTs with tiny nanocrystals of anatase TiO_(2) wrapped in N-doped carbon layers showed a well-defined tube structure with a large specific surface area of 198 m^(2) g^(-1) and a large pore size of~5 nm.The TiO_(2)@NC-NTs delivered high reversible capacities of 158 m A h g^(-1) at 2 C(1 C=335 m A g^(-1))for 2200 cycles and 146 m A h g^(-1) at 5 C for 4000 cycles,as well as an ultrahigh rate capability of up to 40 C with a capacity of 98 m A h g^(-1).Even at a high current density of 10 C,a capacity of 138 m A h g^(-1) could be delivered over 10,000 cycles.Thus,the synthesis of mesoporous TiO_(2)@NC-NTs was demonstrated to be an efficient approach for developing electrode materials with high sodium storage and long cycle life.展开更多
In this talk we focus on the mechanical proper-ties of cellular graphene(CG),and the applica-tions of graphene,and cellular graphene for sen-sors.We report a novel,facile,two-step,adaptable and scalable method of prep...In this talk we focus on the mechanical proper-ties of cellular graphene(CG),and the applica-tions of graphene,and cellular graphene for sen-sors.We report a novel,facile,two-step,adaptable and scalable method of preparingfree-standing CG with tunable densities and adjust-able shapes and sizes.The CG samples展开更多
基金supported by the National Natural Science Foundation of China(32271408,32271296,12202193)National Basic Research Program of China(2021YFA1201404)+2 种基金Natural Science Foundation of Jiangsu Province(BK20232023)Nanjing Health Technology Development Special Project(JQX23002)Jiangsu Provincial Key Medical Center Foundation,Jiangsu Provincial Medical Outstanding Talent Foundation,the Youth Innovation Team of Shaanxi Universities,China.
文摘Neurological disorders exert significantly affect the quality of life for patients,necessitating effective strategies for nerve regeneration.Both traditional autologous nerve transplantation and emerging therapeutic approaches encounter scientific challenges due to the complex nature of the nervous system and the unsuitability of the surrounding environment for cell transplantation.Tissue engineering techniques offer a promising path for neurotherapy.Successful neural tissue engineering relies on modulating cell differentiation behavior and tissue repair by developing biomaterials that mimic the natural extracellular matrix(ECM)and establish a threedimensional microenvironment.Peptide-based hydrogels have emerged as a potent option among these biomaterials due to their ability to replicate the structure and complexity of the ECM.This review aims to explore the diverse range of peptide-based hydrogels used in nerve regeneration with a specific focus on dipeptide hydrogels,tripeptide hydrogels,oligopeptide hydrogels,multidomain peptides(MDPs),and amphiphilic peptide hydrogels(PAs).Peptide-based hydrogels offer numerous advantages,including biocompatibility,structural diversity,adjustable mechanical properties,and degradation without adverse effects.Notably,hydrogels formed from self-assembled polypeptide nanofibers,derived from amino acids,show promising potential in engineering neural tissues,outperforming conventional materials like alginate,poly(ε-caprolactone),and polyaniline.Additionally,the simple design and cost-effectiveness of dipeptidebased hydrogels have enabled the creation of various functional supramolecular structures,with significant implications for nervous system regeneration.These hydrogels are expected to play a crucial role in future neural tissue engineering research.This review aims to highlight the benefits and potential applications of peptidebased hydrogels,contributing to the advancement of neural tissue engineering.
基金We gratefully acknowledge the National Natural Science Foundation of China(Nos.11872132,51803016 and U1837204)the China Postdoctoral Science Foundation(No.2020M673124)+1 种基金the Natural Science Foundation of Chongqing(No.cstc2020jcyj-bshX0001)the Competitive Internal Research Award of Khalifa University(CIRA-2018-16).
文摘Multifunctional and flexible wearable devices play a crucial role in a wide range of applications,such as heath monitoring,intelligent skins,and human-machine interactions.Developing flexible and conductive materials for multifunctional wearable devices with low-cost and high efficiency methods are highly desirable.Here,a conductive graphene/microsphere/bamboo fiber(GMB)nanocomposite paper with hierarchical surface microstructures is successfully fabricated through a simple vacuum-assisted filtration followed by thermo-foaming process.The as-prepared microstructured GMB nanocomposite paper exhibits not only a high volume electrical conductivity of~45 S/m but also an excellent electrical stability(i.e.,relative changes in resistance are less than 3%under stretching,folding,and compressing loadings)due to its unique structure features.With this microstructured nanocomposite paper as active sensing layer,microstructured pressure sensors with a high sensitivity(-4 kPa^(-1)),a wide sensing range(0–5 kPa),and a rapid response time(about 140 ms)are realized.In addition,benefitting from the outstanding electrical stability and mechanical flexibility,the microstructured nanocomposite paper is further demonstrated as a low-voltage Joule heating device.The surface temperature of the microstructured nanocomposite paper rapidly reaches over 80℃ when applying a relatively low voltage of 7 V,indicating its potential in human thermotherapy and thermal management.
基金the financial support provided by internal reseach funding of Khalifa University of Science and Technology,United Arab Emirates(Grant No.CIRA-2018-16)。
文摘Controllable synthesis of insertion-type anode materials with beneficial micro-and nanostructures is a promising approach for the synthesis of sodium-ion storage devices with high-reactivity and excellent electrochemical performance.In this study,we developed a sacrificial-templating route to synthesize TiO_(2)@N-doped carbon nanotubes(TiO_(2)@NC-NTs)with excellent electrochemical performance.The asprepared mesoporous TiO_(2)@NC-NTs with tiny nanocrystals of anatase TiO_(2) wrapped in N-doped carbon layers showed a well-defined tube structure with a large specific surface area of 198 m^(2) g^(-1) and a large pore size of~5 nm.The TiO_(2)@NC-NTs delivered high reversible capacities of 158 m A h g^(-1) at 2 C(1 C=335 m A g^(-1))for 2200 cycles and 146 m A h g^(-1) at 5 C for 4000 cycles,as well as an ultrahigh rate capability of up to 40 C with a capacity of 98 m A h g^(-1).Even at a high current density of 10 C,a capacity of 138 m A h g^(-1) could be delivered over 10,000 cycles.Thus,the synthesis of mesoporous TiO_(2)@NC-NTs was demonstrated to be an efficient approach for developing electrode materials with high sodium storage and long cycle life.
文摘In this talk we focus on the mechanical proper-ties of cellular graphene(CG),and the applica-tions of graphene,and cellular graphene for sen-sors.We report a novel,facile,two-step,adaptable and scalable method of preparingfree-standing CG with tunable densities and adjust-able shapes and sizes.The CG samples
