As a production quality index of hematite grinding process,particle size(PS)is hard to be measured in real time.To achieve the PS estimation,this paper proposes a novel data driven model of PS using stochastic configu...As a production quality index of hematite grinding process,particle size(PS)is hard to be measured in real time.To achieve the PS estimation,this paper proposes a novel data driven model of PS using stochastic configuration network(SCN)with robust technique,namely,robust SCN(RSCN).Firstly,this paper proves the universal approximation property of RSCN with weighted least squares technique.Secondly,three robust algorithms are presented by employing M-estimation with Huber loss function,M-estimation with interquartile range(IQR)and nonparametric kernel density estimation(NKDE)function respectively to set the penalty weight.Comparison experiments are first carried out based on the UCI standard data sets to verify the effectiveness of these methods,and then the data-driven PS model based on the robust algorithms are established and verified.Experimental results show that the RSCN has an excellent performance for the PS estimation.展开更多
双打击淋巴瘤(double hit lymphoma DHL)是具有MYC和BCL-2/BCL-6基因重排的高级别B细胞淋巴瘤。该病患者的预后较差。要明确诊断DHL须完善FISH检查,而该检查在临床上尚未广泛开展,造成了一定量的漏诊。目前DHL仍以化疗为主,大多数患者...双打击淋巴瘤(double hit lymphoma DHL)是具有MYC和BCL-2/BCL-6基因重排的高级别B细胞淋巴瘤。该病患者的预后较差。要明确诊断DHL须完善FISH检查,而该检查在临床上尚未广泛开展,造成了一定量的漏诊。目前DHL仍以化疗为主,大多数患者疗效不佳,国际上对DHL治疗积极进行了探索,免疫疗法和相关途径的靶向药物治疗为DHL的治疗提供了新方向。本文就近年来DHL的诊断和治疗的最新研究进展作一综述。展开更多
基金Projects(61603393,61741318)supported in part by the National Natural Science Foundation of ChinaProject(BK20160275)supported by the Natural Science Foundation of Jiangsu Province,China+1 种基金Project(2015M581885)supported by the Postdoctoral Science Foundation of ChinaProject(PAL-N201706)supported by the Open Project Foundation of State Key Laboratory of Synthetical Automation for Process Industries of Northeastern University,China
文摘As a production quality index of hematite grinding process,particle size(PS)is hard to be measured in real time.To achieve the PS estimation,this paper proposes a novel data driven model of PS using stochastic configuration network(SCN)with robust technique,namely,robust SCN(RSCN).Firstly,this paper proves the universal approximation property of RSCN with weighted least squares technique.Secondly,three robust algorithms are presented by employing M-estimation with Huber loss function,M-estimation with interquartile range(IQR)and nonparametric kernel density estimation(NKDE)function respectively to set the penalty weight.Comparison experiments are first carried out based on the UCI standard data sets to verify the effectiveness of these methods,and then the data-driven PS model based on the robust algorithms are established and verified.Experimental results show that the RSCN has an excellent performance for the PS estimation.
文摘双打击淋巴瘤(double hit lymphoma DHL)是具有MYC和BCL-2/BCL-6基因重排的高级别B细胞淋巴瘤。该病患者的预后较差。要明确诊断DHL须完善FISH检查,而该检查在临床上尚未广泛开展,造成了一定量的漏诊。目前DHL仍以化疗为主,大多数患者疗效不佳,国际上对DHL治疗积极进行了探索,免疫疗法和相关途径的靶向药物治疗为DHL的治疗提供了新方向。本文就近年来DHL的诊断和治疗的最新研究进展作一综述。