In this paper,we formulate the precoding problem of integrated sensing and communication(ISAC)waveform as a non-convex quadratically constrained quadratic programming(QCQP),in which the weighted sum of communication m...In this paper,we formulate the precoding problem of integrated sensing and communication(ISAC)waveform as a non-convex quadratically constrained quadratic programming(QCQP),in which the weighted sum of communication multi-user interference(MUI)and the gap between dual-use waveform and ideal radar waveform is minimized with peak-toaverage power ratio(PAPR)constraints.We propose an efficient algorithm based on alternating direction method of multipliers(ADMM),which is able to decouple multiple variables and provide a closed-form solution for each subproblem.In addition,to improve the sensing performance in both spatial and temporal domains,we propose a new criteria to design the ideal radar waveform,in which the beam pattern is made similar to the ideal one and the integrated sidelobe level of the ambiguity function in each target direction is minimized in the region of interest.The limited memory Broyden-Fletcher-Goldfarb-Shanno(LBFGS)algorithm is applied to the design of the ideal radar waveform which works as a reference in the design of the dual-function waveform.Numerical results indicate that the designed dual-function waveform is capable of offering good communication quality of service(QoS)and sensing performance.展开更多
目的分析非脱羧勒克菌血流感染患者的临床特征,为治疗提供参考。方法报道咸阳市第一人民医院1例非脱羧勒克菌血流感染患者的病历资料,通过文献检索英文数据库PubMed、Embase、Springer、Web of Science,中文数据库中国知网、万方、维普...目的分析非脱羧勒克菌血流感染患者的临床特征,为治疗提供参考。方法报道咸阳市第一人民医院1例非脱羧勒克菌血流感染患者的病历资料,通过文献检索英文数据库PubMed、Embase、Springer、Web of Science,中文数据库中国知网、万方、维普、中国生物医学文献服务系统,纳入符合标准的文献18篇,加上该医院1例患者共19例。回顾性分析19例患者的年龄、性别、免疫状态、基础情况、是否入住重症医学科、侵袭性操作、药敏试验、治疗药物以及临床转归,总结特点,为临床治疗提供参考。结果19例非脱羧勒克菌血流感染患者的性别无显著差异,年龄分布为儿童5例,青年人10例,老年人4例;有13例患者免疫功能低下,6例患者免疫功能正常;10例患者存在侵袭性操作(中心静脉置管患者数量最多),9例患者入住重症医学科。非脱羧勒克菌对大多数抗菌药物敏感性较好,产超广谱β内酰胺酶菌株及耐碳青霉烯类菌株也有检出;药物治疗选择主要基于药敏试验结果。有4例为非脱羧勒克菌感染导致死亡,其中儿童3例,成人1例。结论非脱羧勒克菌血流感染主要为免疫功能低下人群,新生儿预后较成人差,中心静脉置管及入住重症医学科的患者应引起临床重视。展开更多
目的:分析我院2014—2017年药品不良反应(adverse drug reaction,ADR)发生的特点及相关因素,总结规律,借以促进临床合理用药。方法:采用回顾性分析方法,对我院2014—2017年上报至国家药品不良反应监测网的750例ADR报告进行分类统计与分...目的:分析我院2014—2017年药品不良反应(adverse drug reaction,ADR)发生的特点及相关因素,总结规律,借以促进临床合理用药。方法:采用回顾性分析方法,对我院2014—2017年上报至国家药品不良反应监测网的750例ADR报告进行分类统计与分析。结果:750例ADR中,年龄大于50岁的患者构成比最高,涉及的药品有213种,其中以抗感染药物诱发的ADR居多(33. 73%),静脉滴注给药是引发ADR的主要途径(77. 33%),临床表现以皮肤及其附件损害为主。结论:临床应重视ADR监测和报告工作,密切观察患者用药后的临床表现和反应,以促进临床合理用药,保障患者用药安全。展开更多
基金supported in part by the National Natural Science Foundation of China under Grant 62271142in part by the Key Research and Development Program of Jiangsu Province BE2023021+2 种基金in part by the Jiangsu Key Research and Development Program Project under Grant BE2023011-2in part by the Young Scholar Funding of Southeast Universityin part by the Fundamental Research Funds for the Central Universities 2242022k60001。
文摘In this paper,we formulate the precoding problem of integrated sensing and communication(ISAC)waveform as a non-convex quadratically constrained quadratic programming(QCQP),in which the weighted sum of communication multi-user interference(MUI)and the gap between dual-use waveform and ideal radar waveform is minimized with peak-toaverage power ratio(PAPR)constraints.We propose an efficient algorithm based on alternating direction method of multipliers(ADMM),which is able to decouple multiple variables and provide a closed-form solution for each subproblem.In addition,to improve the sensing performance in both spatial and temporal domains,we propose a new criteria to design the ideal radar waveform,in which the beam pattern is made similar to the ideal one and the integrated sidelobe level of the ambiguity function in each target direction is minimized in the region of interest.The limited memory Broyden-Fletcher-Goldfarb-Shanno(LBFGS)algorithm is applied to the design of the ideal radar waveform which works as a reference in the design of the dual-function waveform.Numerical results indicate that the designed dual-function waveform is capable of offering good communication quality of service(QoS)and sensing performance.
文摘目的分析非脱羧勒克菌血流感染患者的临床特征,为治疗提供参考。方法报道咸阳市第一人民医院1例非脱羧勒克菌血流感染患者的病历资料,通过文献检索英文数据库PubMed、Embase、Springer、Web of Science,中文数据库中国知网、万方、维普、中国生物医学文献服务系统,纳入符合标准的文献18篇,加上该医院1例患者共19例。回顾性分析19例患者的年龄、性别、免疫状态、基础情况、是否入住重症医学科、侵袭性操作、药敏试验、治疗药物以及临床转归,总结特点,为临床治疗提供参考。结果19例非脱羧勒克菌血流感染患者的性别无显著差异,年龄分布为儿童5例,青年人10例,老年人4例;有13例患者免疫功能低下,6例患者免疫功能正常;10例患者存在侵袭性操作(中心静脉置管患者数量最多),9例患者入住重症医学科。非脱羧勒克菌对大多数抗菌药物敏感性较好,产超广谱β内酰胺酶菌株及耐碳青霉烯类菌株也有检出;药物治疗选择主要基于药敏试验结果。有4例为非脱羧勒克菌感染导致死亡,其中儿童3例,成人1例。结论非脱羧勒克菌血流感染主要为免疫功能低下人群,新生儿预后较成人差,中心静脉置管及入住重症医学科的患者应引起临床重视。
文摘目的:分析我院2014—2017年药品不良反应(adverse drug reaction,ADR)发生的特点及相关因素,总结规律,借以促进临床合理用药。方法:采用回顾性分析方法,对我院2014—2017年上报至国家药品不良反应监测网的750例ADR报告进行分类统计与分析。结果:750例ADR中,年龄大于50岁的患者构成比最高,涉及的药品有213种,其中以抗感染药物诱发的ADR居多(33. 73%),静脉滴注给药是引发ADR的主要途径(77. 33%),临床表现以皮肤及其附件损害为主。结论:临床应重视ADR监测和报告工作,密切观察患者用药后的临床表现和反应,以促进临床合理用药,保障患者用药安全。
