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T1期结直肠癌淋巴结转移风险因素的研究进展
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作者 李林骏 石素钰洁(综述) 杨雅莹(审校) 《中国肿瘤临床》 CAS CSCD 北大核心 2024年第7期372-376,共5页
随着内镜技术的发展,结直肠癌的早筛得以广泛推广,越来越多的T1期结直肠癌患者接受了肿瘤内镜切除。T1期结直肠癌内镜切除后是否需要进一步追加肠段切除并进行区域淋巴结的清扫,应根据组织病理学结果判断淋巴结转移的风险。根据目前国... 随着内镜技术的发展,结直肠癌的早筛得以广泛推广,越来越多的T1期结直肠癌患者接受了肿瘤内镜切除。T1期结直肠癌内镜切除后是否需要进一步追加肠段切除并进行区域淋巴结的清扫,应根据组织病理学结果判断淋巴结转移的风险。根据目前国内外指南中的风险因素进行追加手术后,结果仅约10%的T1型结直肠癌患者发现淋巴结转移,其余患者并未发现存在淋巴结转移,导致了大量的追加手术切除无临床获益。因此,目前亟需一项更为准确的淋巴结转移风险评估体系来解决该问题,本文就T1期结直肠癌淋巴结转移的风险因素评估体系的现状进行综述,并探讨其发展前景。 展开更多
关键词 早期结直肠癌 淋巴结转移 临床病理特征
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Passively Q-switched diode-pumped Tm,Ho:LuVO4 laser with a black phosphorus saturable absorber 被引量:2
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作者 linjun li Tianxin li +4 位作者 Long Zhou Jianying Fan Yuqiang Yang Wenqiang Xie Shasha li 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第9期203-205,共3页
We presented a passively Q-switched(PQS) diode-pumped c-cut Tm, Ho:LuVO_4 laser with a black phosphorus saturable absorber for the first time.Under PQS mode, an average output power of 0.86 W and a peak power of 2.32 ... We presented a passively Q-switched(PQS) diode-pumped c-cut Tm, Ho:LuVO_4 laser with a black phosphorus saturable absorber for the first time.Under PQS mode, an average output power of 0.86 W and a peak power of 2.32 W were acquired from the Tm, Ho:LuVO4 laser with the pump power of 14.55 W, corresponding to a pulse width of 2.89 μs,a pulse repetition rate of 71.84 kHz, and a pulse energy of about 6.70 μJ. 展开更多
关键词 passively Q-switched(PQS) technology Tm Ho:LuVO4 crystal pulse WIDTH
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New insight into scale inhibition during tea brewing: Ca^(2+)/Mg^(2+) complexing and alkalinity consumption
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作者 linjun li Jinsuo Lu +5 位作者 Heliang Pang Zhiqiang Zhang Jing Yang Pengpeng li Xiaoyu Yan Miaomiao Fan 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2023年第2期901-914,共14页
Scale not only affects the taste and color ofwater,but also increases the risks of osteoporosis and cardiovascular diseases associated with drinking it.As a popular beverage,tea is rich many substances that have consi... Scale not only affects the taste and color ofwater,but also increases the risks of osteoporosis and cardiovascular diseases associated with drinking it.As a popular beverage,tea is rich many substances that have considerable potential for scale inhibition,including protein,tea polyphenols and organic acids.In this study,the effect of tea brewing on scale formationwas explored.It was found that the proteins,catechins and organic acids in tea leaves could be released when the green tea was brewed in water with sufficient hardness and alkalinity.The tea-released protein was able to provide carboxyl groups to chelate with calcium ions(Ca^(2+)),preventing the Ca^(2+)from reacting with the carbonate ions(CO_(3)^(2-)).The B rings of catechins were another important structure in the complexation of Ca^(2+)and magnesium ions(Mg2+).The carboxyl and hydroxyl groups on the organic acids was able to form fivemembered chelating rings with Ca^(2+)and Mg^(2+),resulting in a significant decrease in Ca^(2+)from 100.0 to 60.0 mg/L.Additionally,the hydrogen ions(H^(+))provided by the organic acids consumed and decreased the alkalinity of the water from 250.0 to 131.4 mg/L,leading to a remarkable reduction in pH from 8.93 to 7.73.It further prevented the bicarbonate(HCO_(3)^(-))from producing CO_(3)^(2−)when the water was heated.The reaction of the tea constituents with the hardness and alkalinity inhibited the formation of scale,leading to a significant decrease in turbidity from 10.6 to 1.4 NTU.Overall,this study provides information to help build towards an understanding of the scale inhibition properties of tea and the prospects of tea for anti-scaling in industrial applications. 展开更多
关键词 Scale inhibition Tea brewing CHELATION Hardness ALKALINITY
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Demonstration of a petawatt-scale optical parametric chirped pulse amplifier based on yttrium calcium oxyborate
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作者 Meizhi Sun Jun Kang +13 位作者 Xiao liang Haidong Zhu Qingwei Yang Qi Gao Ailin Guo Ping Zhu Panzheng Zhang linjun li lijuan Qiu Zhantao Lu Sheng Wang Xiaoniu Tu Xinglong Xie Jianqiang Zhu 《High Power Laser Science and Engineering》 SCIE CAS CSCD 2023年第1期11-17,共7页
As optical parametric chirped pulse amplification has been widely adopted for the generation of extreme intensity laser sources,nonlinear crystals of large aperture are demanded for high-energy amplifiers.Yttrium calc... As optical parametric chirped pulse amplification has been widely adopted for the generation of extreme intensity laser sources,nonlinear crystals of large aperture are demanded for high-energy amplifiers.Yttrium calcium oxyborate(YCa_(4)O(BO_(3))_(3),YCOB)is capable of being grown with apertures exceeding 100 mm,which makes it possible for application in systems of petawatt scale.In this paper,we experimentally demonstrated for the first time to our knowledge,an ultra-broadband non-collinear optical parametric amplifier with YCOB for petawatt-scale compressed pulse generation at 800 nm.Based on the SG-II 5 PW facility,amplified signal energy of approximately 40 J was achieved and pump-to-signal conversion efficiency was up to 42.3%.A gain bandwidth of 87 nm was realized and supported a compressed pulse duration of 22.3 fs.The near-field and wavefront aberration represented excellent characteristics,which were comparable with those achieved in lithium triborate-based amplifiers.These results verified the great potential for YCOB utilization in the future. 展开更多
关键词 optical parametric amplification PETAWATT ultra-short pulse yttrium calcium oxyborate
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Mechanism of adjusting bypass ratio by front variable area bypass injector for a variable cycle engine
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作者 Qian li Chen XIA +3 位作者 Guoping HUANG Omer MUSA linjun li Zonghan YU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2024年第10期158-171,共14页
The Front Variable Area Bypass Injector(FVABI)is a key to bypass ratio adjustment for a Variable Cycle Engine(VCE).In order to study the role of the FVABI with the Core Driven Fan Stage(CDFS)duct,firstly,the engine by... The Front Variable Area Bypass Injector(FVABI)is a key to bypass ratio adjustment for a Variable Cycle Engine(VCE).In order to study the role of the FVABI with the Core Driven Fan Stage(CDFS)duct,firstly,the engine bypass with the CDFS duct model and the equivalent engine bypass without the CDFS duct model are designed using the concept of a jet boundary line.By comparing the difference between airflow driving forces in the two engine bypass models,the quantitative effects of the injection from the CDFS duct on the mass flow rate of the engine bypass airflow are obtained under different combinations of pressure difference and area ratios.Then,the CDFS duct injection characteristic map is obtained through the typical experiment of the FVABI.Based on this map,the performance model of the FVABI is developed.Finally,the turbofan engine model with the Variable Inlet Guide Vane(VIGV),the First Variable Cycle Engine model(VCE1)with the CDFS duct and without the VIGV,and the Second Variable Cycle Engine model(VCE2)with the CDFS duct and VIGV are built.The gain on the engine bypass ratio adjustment range caused by the injection from the CDFS duct is clarified by comparing the three engine models.It is concluded that the bypass ratio adjustment range of the variable cycle engine with the FVABI is about twice that of the traditional turbofan engine. 展开更多
关键词 Front variable area bypass injector Variable cycle engine Bypass ratio Injection CDFS duct injection characteristic map
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The rise of non-vdW moiré superlattices
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作者 Zicheng li Xinyu Duan +2 位作者 Zehui Zhou linjun li Beibei Xu 《The Innovation》 EI 2024年第6期35-36,共2页
The formation of a moirésuperlattice is induced by the stacking of van der Waals(vdW)2D materials with a twist angle or small lattice mismatch.This superlattice functions as a periodic potential for electrons,for... The formation of a moirésuperlattice is induced by the stacking of van der Waals(vdW)2D materials with a twist angle or small lattice mismatch.This superlattice functions as a periodic potential for electrons,forming moiréflat bands with emerging quantum phenomena or highly correlated states. 展开更多
关键词 SUPERLATTICE TWIST BANDS
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FGF8-mediated signaling regulates tooth developmental pace during odontogenesis 被引量:2
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作者 Chensheng lin Ningsheng Ruan +5 位作者 linjun li Yibin Chen Xiaoxiao Hu YiPing Chen Xuefeng Hu Yanding Zhang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2022年第1期40-53,共14页
The developing human and mouse teeth constitute an ideal model system to study the regulatory mechanism underlying organ growth control since their teeth share highly conserved and well-characterized developmental pro... The developing human and mouse teeth constitute an ideal model system to study the regulatory mechanism underlying organ growth control since their teeth share highly conserved and well-characterized developmental processes, and their developmental tempo varies notably. In the current study, we manipulated heterogenous recombination between human and mouse dental tissues and demonstrated that the dental mesenchyme dominates the tooth developmental tempo and FGF8 could be a critical player during this developmental process. Forced activation of FGF8 signaling in the dental mesenchyme of mice promoted cell proliferation, prevented cell apoptosis via p38 and perhaps PI3 K-Akt intracellular signaling,and impelled the transition of the cell cycle from G1-to S-phase in the tooth germ, resulting in the slowdown of the tooth developmental pace. Our results provide compelling evidence that extrinsic signals can profoundly affect tooth developmental tempo, and the dental mesenchymal FGF8 could be a pivotal factor in controlling the developmental pace in a non-cell-autonomous manner during mammalian odontogenesis. 展开更多
关键词 FGF8 TOOTH Developmental pace Non-cell-autonomous
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Active/passive Q-switching operation of 2 μm Tm,Ho:YAP laser with an acousto-optical Q-switch/MoS_2 saturable absorber mirror 被引量:5
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作者 linjun li XINING YANG +9 位作者 LONG ZHOU WENQIANG XIE YUNLONG WANG YINGJIE SHEN YUQIANG YANG WENLONG YANG WEI WANG ZHIWEI LV XIAOMING DUAN MINGHUA CHEN 《Photonics Research》 SCIE EI 2018年第6期614-619,共6页
The active/passive Q-switching operation of a 2 [tm a-cut Tm,Ho:YAP laser was experimentally demonstrated with an acousto-optical Q-switch/MoS2 saturable absorber mirror. The active Q-switch laser was operated for th... The active/passive Q-switching operation of a 2 [tm a-cut Tm,Ho:YAP laser was experimentally demonstrated with an acousto-optical Q-switch/MoS2 saturable absorber mirror. The active Q-switch laser was operated for the first time, to the best of our knowledge, with an average output power of 12.3 W and a maximum pulse energy of 10.3 mJ. The passive Q-switch laser was also the first acquired with an average output power of 3.3 W and per pulse energy of 23.31 μJ, and the beam quality factors of Mx^2 = 1.06 and My^2 = 1.06 were measured at the average output power of 2 W. 展开更多
关键词 LASERS Q-SWITCHED LASERS SOLID-STATE
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Polarized Water Driven Dynamic PN Junction-Based Direct-Current Generator 被引量:2
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作者 Yanghua Lu Yanfei Yan +8 位作者 Xutao Yu Xu Zhou Sirui Feng Chi Xu Haonan Zheng Zunshan Yang linjun li Kaihui liu Shisheng lin 《Research》 SCIE EI CAS CSCD 2021年第1期469-478,共10页
There is a rising prospective in harvesting energy from the environment,as in situ energy is required for the distributed sensors in the interconnected information society,among which the water flow energy is the most... There is a rising prospective in harvesting energy from the environment,as in situ energy is required for the distributed sensors in the interconnected information society,among which the water flow energy is the most potential candidate as a clean and abundant mechanical source.However,for microscale and unordered movement of water,achieving a sustainable direct-current generating device with high output to drive the load element is still challenging,which requires for further exploration.Herein,we propose a dynamic PN water junction generator with moving water sandwiched between two semiconductors,which outputs a sustainable direct-current voltage of 0.3 V and a current of 0.64μA.The mechanism can be attributed to the dynamic polarization process of water as moving dielectric medium in the dynamic PN water junction,under the Fermi level difference of two semiconductors.We further demonstrate an encapsulated portable power-generating device with simple structure and continuous direct-current voltage output of 0.11 V,which exhibits its promising potential application in the field of wearable devices and the IoTs. 展开更多
关键词 WEAR GENERATING MOVING
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Anisotropic gapping of topological Weyl rings in the charge-density-wave superconductor In_(x)TaSe_(2) 被引量:1
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作者 Yupeng li Yi Wu +19 位作者 Chenchao Xu Ningning liu Jiang Ma Baijiang Lv Gang Yao Yan liu Hua Bai Xiaohui Yang Lei Qiao Miaocong li linjun li Hui Xing Yaobo Huang Junzhang Ma Ming Shi Chao Cao Yang liu Canhua liu Jinfeng Jia Zhu-An Xu 《Science Bulletin》 SCIE EI CSCD 2021年第3期243-249,M0004,共8页
Topological materials and topological phases have recently become a hot topic in condensed matter physics.In this work,we report an In-intercalated transition-metal dichalcogenide In_(x)TaSe_(2)(named 112 system),a to... Topological materials and topological phases have recently become a hot topic in condensed matter physics.In this work,we report an In-intercalated transition-metal dichalcogenide In_(x)TaSe_(2)(named 112 system),a topological nodal-line semimetal in the prep seffiffinffi ce of both charge density wave(CDW)and superconductivity.In the x=0.58 sample,the 2×√3 commensurate CDW(CCDW)and the 2×2 CCDW are observed below 116 and 77 K,respectively.Consistent with theoretical calculations,the spin–orbital coupling gives rise to two twofold-degenerate nodal rings(Weyl rings)connected by drumhead surface states,confirmed by angle-resolved photoemission spectroscopy.Our results suggest that the 2×2 CCDW ordering gaps out one Weyl ring in accordance with the CDW band folding,while the other Weyl ring remains gapless with intact surface states.In addition,superconductivity emerges at 0.91 K,with the upper critical field deviating from the s-wave behavior at low temperature,implying possibly unconventional superconductivity.Therefore,we think this type of the 112 system may possess abundant physical states and offer a platform to investigate the interplay between CDW,nontrivial band topology and superconductivity. 展开更多
关键词 Nodal-line semimetal Charge density wave Superconductivity DFT calculations Weyl rings
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