目的探讨氟比洛芬酯在宫颈癌手术患者围术期镇痛效果及对免疫系统的影响,为治疗宫颈癌提供理论依据。方法选取100例择期行宫颈癌根除术患者为研究对象,随机分为2组,观察组50例患者,采用氟比洛芬酯镇痛,对照组50例患者,对应的注射等量生...目的探讨氟比洛芬酯在宫颈癌手术患者围术期镇痛效果及对免疫系统的影响,为治疗宫颈癌提供理论依据。方法选取100例择期行宫颈癌根除术患者为研究对象,随机分为2组,观察组50例患者,采用氟比洛芬酯镇痛,对照组50例患者,对应的注射等量生理盐水。观察记录患者的一般病理特征。视觉模拟评分和舒适评分,记录患者体温、恶性呕吐及患者失血量、白细胞水平和肛门排气时间、CD3^+、CD4^+、CD8+、CD4^+/CD8+和CD25^+等指标。结果观察组患者术后12 h、24 h、36 h和48 h视觉模拟评分均低于对照组患者、舒适评分均高于对照组患者,差异有统计学意义(P<0.05);观察组患者肛门恢复排气时间短于对照组患者,恶心呕吐发生率明显低于对照组患者,观察组患者手术之后白细胞水平低于对照组患者,观察组患者手术之后24 h体温升高幅度小于对照组患者,差异有统计学意义(P<0.05);2组患者各项T淋巴细胞均在术后24 h达到最低,观察组患者术后24 h CD8+和CD4^+/CD8+高于对照组,差异有统计学意义(P<0.05),观察组患者术后48 h CD4^+和CD4^+/CD8+高于对照组,差异有统计学意义(P<0.05);观察组患者术后24 h和48 h CD25^+水平均高于对照组患者,差异有统计学意义(P<0.05)。结论氟比洛芬酯对宫颈癌手术患者围术期具有较好的镇痛效果,对患者免疫功能有一定的保护作用,临床效果好。展开更多
With the improvement of living standards, people are paying more and more attention to health problems. The antibacterial function of fabrics is therefore of great importance. The structural color(photonic crystal), w...With the improvement of living standards, people are paying more and more attention to health problems. The antibacterial function of fabrics is therefore of great importance. The structural color(photonic crystal), which has been widely investigated and applied on fabric dyeing, contains a large number of hollow microstructure and functional groups, and is easy to be modified and functionalized. Therefore, an innovative way of endowing structural color dye on fabrics with antibacterial property was presented in this paper. The latex spheres and zinc pyrrolidone were co-assembled on polydopamine modified fabrics, antibacterial ion zinc pyrrolidone was therefore loaded into the pores of structural color dye, and brilliant antibacterial fabrics were successfully achieved. The existence of zinc pyrrolidone had little influence on the color saturation of brilliant structural color and meanwhile ensured the structural color dye excellent antibacterial effect. The antibacterial reduction rate of the antibacterial fabric reached 99.99%. Owing to the addition of polyurethane(PUA) coating on the surface of structural color, the fabric modified by the antibacterial structural color dye also presented good washing resistance, which showed great application possibility in functional textile and antibacterial fields.展开更多
文摘目的探讨氟比洛芬酯在宫颈癌手术患者围术期镇痛效果及对免疫系统的影响,为治疗宫颈癌提供理论依据。方法选取100例择期行宫颈癌根除术患者为研究对象,随机分为2组,观察组50例患者,采用氟比洛芬酯镇痛,对照组50例患者,对应的注射等量生理盐水。观察记录患者的一般病理特征。视觉模拟评分和舒适评分,记录患者体温、恶性呕吐及患者失血量、白细胞水平和肛门排气时间、CD3^+、CD4^+、CD8+、CD4^+/CD8+和CD25^+等指标。结果观察组患者术后12 h、24 h、36 h和48 h视觉模拟评分均低于对照组患者、舒适评分均高于对照组患者,差异有统计学意义(P<0.05);观察组患者肛门恢复排气时间短于对照组患者,恶心呕吐发生率明显低于对照组患者,观察组患者手术之后白细胞水平低于对照组患者,观察组患者手术之后24 h体温升高幅度小于对照组患者,差异有统计学意义(P<0.05);2组患者各项T淋巴细胞均在术后24 h达到最低,观察组患者术后24 h CD8+和CD4^+/CD8+高于对照组,差异有统计学意义(P<0.05),观察组患者术后48 h CD4^+和CD4^+/CD8+高于对照组,差异有统计学意义(P<0.05);观察组患者术后24 h和48 h CD25^+水平均高于对照组患者,差异有统计学意义(P<0.05)。结论氟比洛芬酯对宫颈癌手术患者围术期具有较好的镇痛效果,对患者免疫功能有一定的保护作用,临床效果好。
基金National Nature Science Foundation of China(No.51503034)Science and Technology Commission of Shanghai Municipality for Yangfan Program,China(No.15YF1400700)。
文摘With the improvement of living standards, people are paying more and more attention to health problems. The antibacterial function of fabrics is therefore of great importance. The structural color(photonic crystal), which has been widely investigated and applied on fabric dyeing, contains a large number of hollow microstructure and functional groups, and is easy to be modified and functionalized. Therefore, an innovative way of endowing structural color dye on fabrics with antibacterial property was presented in this paper. The latex spheres and zinc pyrrolidone were co-assembled on polydopamine modified fabrics, antibacterial ion zinc pyrrolidone was therefore loaded into the pores of structural color dye, and brilliant antibacterial fabrics were successfully achieved. The existence of zinc pyrrolidone had little influence on the color saturation of brilliant structural color and meanwhile ensured the structural color dye excellent antibacterial effect. The antibacterial reduction rate of the antibacterial fabric reached 99.99%. Owing to the addition of polyurethane(PUA) coating on the surface of structural color, the fabric modified by the antibacterial structural color dye also presented good washing resistance, which showed great application possibility in functional textile and antibacterial fields.
