Fibre-reinforced polymer(FRP)has the advantages of high strength,light weight,corrosion resistance and convenient construction and is widely used in repairing and strengthening damaged concrete columns.Most of the exi...Fibre-reinforced polymer(FRP)has the advantages of high strength,light weight,corrosion resistance and convenient construction and is widely used in repairing and strengthening damaged concrete columns.Most of the existing strength models were built by regression analysis of experimental data;however,in this article,a new unified strength model is proposed using the Hoek-Brown failure criterion.To study the strength of FRP-confined damaged and undamaged concrete columns,900 test data were collected from the published literature and a large database that contains the cross-sectional shape of each specimen,the damage type,the damage level and the FRP-confined stiffness was established.A new strength model using the Hoek-Brown failure criterion was established and is suitable for both circular and square columns that are undamaged,load-damaged and fire-damaged.Based on the database,most of the existing strength models from the published literature and the model proposed in this paper were evaluated.The evaluation shows that the proposed model can predict the compressive strength for FRP-confined pre-damaged and undamaged concrete columns with good accuracy.展开更多
【目的】探讨载脂蛋白E(ApoE)基因、临床特征与老年患者全麻术后认知功能障碍(POCD)的关系。【方法】本院收治的122例采用丙泊酚麻醉诱导全麻手术的老年患者,患者均行ApoE基因及基因型检测,并采用简易智力状态检查量表(MMSE)评估患者术...【目的】探讨载脂蛋白E(ApoE)基因、临床特征与老年患者全麻术后认知功能障碍(POCD)的关系。【方法】本院收治的122例采用丙泊酚麻醉诱导全麻手术的老年患者,患者均行ApoE基因及基因型检测,并采用简易智力状态检查量表(MMSE)评估患者术后POCD发生情况。分析ApoE基因与老年丙泊酚麻醉诱导全麻术后POCD的关系。【结果】患者术前认知功能均正常,MMSE评分为(28.51±1.12)分,术后24 h MMSE评分为(26.01±1.32)分,术后72 h MMSE评分为(26.81±1.05)分,术后7 d MMSE评分为(27.41±1.06)分。发生POCD 36例,占29.51%,纳入POCD组;未发生POCD 86例,占70.49%,纳入非POCD组。POCD组患者年龄、ε3/4及ε4基因携带频率显著高于非POCD组(P<0.05),ε3/3基因型携带频率显著低于非POCD组(P<0.05)。多因素Logistic回归分析显示,年龄及ε3/3、ε3/4、ε4基因型携带情况是老年丙泊酚麻醉诱导全麻术后POCD的独立影响因素(P<0.05)。【结论】ApoE基因分布可能与老年丙泊酚麻醉诱导全麻术后POCD发生机制有关。展开更多
基金Project(2017M622540)supported by the China Postdoctoral Science FoundationProject(51808419)supported by the National Natural Science Foundation of China+1 种基金Project(2019CFB217)supported by the National Natural Science Foundation of Hubei Province,ChinaProject(201623)supported by the Science and Technology Project of Wuhan Urban and Rural Construction Committee,China。
文摘Fibre-reinforced polymer(FRP)has the advantages of high strength,light weight,corrosion resistance and convenient construction and is widely used in repairing and strengthening damaged concrete columns.Most of the existing strength models were built by regression analysis of experimental data;however,in this article,a new unified strength model is proposed using the Hoek-Brown failure criterion.To study the strength of FRP-confined damaged and undamaged concrete columns,900 test data were collected from the published literature and a large database that contains the cross-sectional shape of each specimen,the damage type,the damage level and the FRP-confined stiffness was established.A new strength model using the Hoek-Brown failure criterion was established and is suitable for both circular and square columns that are undamaged,load-damaged and fire-damaged.Based on the database,most of the existing strength models from the published literature and the model proposed in this paper were evaluated.The evaluation shows that the proposed model can predict the compressive strength for FRP-confined pre-damaged and undamaged concrete columns with good accuracy.
文摘【目的】探讨载脂蛋白E(ApoE)基因、临床特征与老年患者全麻术后认知功能障碍(POCD)的关系。【方法】本院收治的122例采用丙泊酚麻醉诱导全麻手术的老年患者,患者均行ApoE基因及基因型检测,并采用简易智力状态检查量表(MMSE)评估患者术后POCD发生情况。分析ApoE基因与老年丙泊酚麻醉诱导全麻术后POCD的关系。【结果】患者术前认知功能均正常,MMSE评分为(28.51±1.12)分,术后24 h MMSE评分为(26.01±1.32)分,术后72 h MMSE评分为(26.81±1.05)分,术后7 d MMSE评分为(27.41±1.06)分。发生POCD 36例,占29.51%,纳入POCD组;未发生POCD 86例,占70.49%,纳入非POCD组。POCD组患者年龄、ε3/4及ε4基因携带频率显著高于非POCD组(P<0.05),ε3/3基因型携带频率显著低于非POCD组(P<0.05)。多因素Logistic回归分析显示,年龄及ε3/3、ε3/4、ε4基因型携带情况是老年丙泊酚麻醉诱导全麻术后POCD的独立影响因素(P<0.05)。【结论】ApoE基因分布可能与老年丙泊酚麻醉诱导全麻术后POCD发生机制有关。
