AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations.METHODS Ninety-nine kidney transplant recipients(KTRs) w...AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations.METHODS Ninety-nine kidney transplant recipients(KTRs) were assigned to interventional exercise(Group A; n = 52) and a usual care cohort(Group B; n = 47). Blood and urine chemistry, exercise capacity, muscular strength, anthropometric measures and health-related quality of life(HRQo L) were assessed at baseline, and after 6 and 12 mo. Group A underwent a supervised training three times per week for 12 mo. Group B received only general recommendations about home-based physical activities.RESULTS Eighty-five KTRs completed the study(Group A, n = 44; Group B, n = 41). After 12 mo, renal function remained stable in both groups. Group A significantly increased maximum workload(+13 W, P = 0.0003), V'O2 peak(+3.1 mL/kg per minute, P = 0.0099), muscular strength in plantar flexor(+12 kg, P = 0.0368), height in the countermovement jump(+1.9 cm, P = 0.0293) and decreased in Body Mass Index(-0.5 kg/m^2, P = 0.0013). HRQo L significantly improved in physical function(P = 0.0019), physical-role limitations(P = 0.0321) and social functioning scales(P = 0.0346). Noimprovements were found in Group B.CONCLUSION Twelve-month of supervised aerobic and resistance training improves the physiological variables related to physical fitness and cardiovascular risks without consequences on renal function. Recommendations alone are not sufficient to induce changes in exercise capacity of KTRs. Our study is an example of collaborative working between transplant centres, sports medicine and exercise facilities.展开更多
The daily evaluation of the life style is funda- mental for the “exercise as prescription” to re- duce the cardiovascular risks factors. The reg- istration by an accelerometer can identify active from inactive subje...The daily evaluation of the life style is funda- mental for the “exercise as prescription” to re- duce the cardiovascular risks factors. The reg- istration by an accelerometer can identify active from inactive subjects. The aim of the present study is to verify, in a small cohort of subjects at high risk level (obese–hypertensive), the health outcomes. A group of 22 subjects were evalu- ated by the questionnaire and also by an accel- erometer positioned on belt for 5 days to estab- lish the daily Physical Activity Level (PAL).The anthropometrics parameters, Body Mass Index (BMI), Waist Circumference, Hip Circumference, Fat Mass, Free Fat Mass, Total Body–Intracellular and Extracellular Water and Phase Angle (PA) were measured at the beginning and after 3 months of regular exercise. The amount of the exercise prescribed for three months and at least 3 times in a weak, was determined by the Cardiopulmonary test at the 60% of the VO2. Sta-tistical analysis included T-Student test for paired data with a significance at P < 0.05value. Respect of the questionnaire the accelerometer report showed a predominantly inactive life style (PAL = 1.49 ± 0.13). After three months the BMI was significantly reduced in all (p < 0.05) and in addi-tion a trend toward a reduction was also observed for Fatty Mass and for the body composition parameters. The employment of the accelerometer is therefore associated to an improvement of the parameters strongly related with the cardiovascular risk. The results obtained are suggestive for an educational role of this tool in subjects at high risk level.展开更多
The Aerobic Threshold (AerT), is an aged cardiovascular parameter not commonly used to evaluate the heart’s performance in athletes. It indirectly evaluated by ventilator parameters during Cardio Pulmonary Test (CPT)...The Aerobic Threshold (AerT), is an aged cardiovascular parameter not commonly used to evaluate the heart’s performance in athletes. It indirectly evaluated by ventilator parameters during Cardio Pulmonary Test (CPT). Considering that” exercise as prescription therapy “for the diseases, includes training normally established around at the 40% of the peak VO2, this parameter could be taken in care as initial level for the effort prescribed. The aim of the study was to estimate the behavior of the AerT and also Anaerobic Threshold (AT), VO2max in sedentary people. A group of athletes coming from different sports at the same and highest dynamic component were enrolled as control. A group of 41 athletes (16 soccer, 10 basket and 15 cyclists) and 9 healthy subjects were submitted to a CPT. The AerT, AT (assessed by Vslope method) and VO2max were evaluated. The statistical analysis was performed with T student test (P < 0.05 significant). As expected in sedentary all the values were lower than athletes, however for Aer T value appears to be not significantly inferior respect of this one, with the exclusion of the comparison with the cyclists. In sedentary the AerT measure seems to give additional information in evaluating the cardiovascular performance. The VO2max and AT remain the main parameters in defining the athletes performance. Therefore we cannot exclude any further utility of the AerT in normal subject but regularly trained.展开更多
Objective: Bicuspid Aortic Valve (BAV) is normally asymptomatic for a long time in both the general population and regularlytrained athletes. The study aimed to evaluate the role of physical stress echocardiography in...Objective: Bicuspid Aortic Valve (BAV) is normally asymptomatic for a long time in both the general population and regularlytrained athletes. The study aimed to evaluate the role of physical stress echocardiography in early identification of any possible dissimilarities in the Left Ventricle (LV) performance and the valve functioning of asymptomatic BAV athletes as compared to the Tricuspid Aortic Valve (TAV) athletes. Design: Data were collected for BAV and TAV athletes from echocardographic examinations to evaluate any possible differences between them. Setting: Sport Medicine Center University of FlorenceItaly. Participants: 66 male BAV athletes and 45 TAV athletes Assessment of risk factors: decrease in LV performance and aortic valve dysfunction during stress test. Main outcome measures: Measure of the standard echocardiographic parameters. Comparison of LV Ejection Fraction (EF) and Aortic Peak Flow Velocity (APFV) data in the two groups at rest and after stress. Results: At rest, values were normal in both groups, although LV systolic diameters tended to be higher in BAV. After physical effort, APFV and EF showed a significant increase in both groups, and for the former the values were at the upper limits in BAV (2.55 m/s BAV 2.12 m/s TAV). Conclusions: The data confirm normal LV performance in asymptomatic BAV athletes. Considering the tendency of this group to show slight enhancement of both APFV and LV dimensions in this group periodical evaluation with physical stress echography might be proposed as a followup procedure for early detection of any additional effect of physical exercise.展开更多
文摘AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations.METHODS Ninety-nine kidney transplant recipients(KTRs) were assigned to interventional exercise(Group A; n = 52) and a usual care cohort(Group B; n = 47). Blood and urine chemistry, exercise capacity, muscular strength, anthropometric measures and health-related quality of life(HRQo L) were assessed at baseline, and after 6 and 12 mo. Group A underwent a supervised training three times per week for 12 mo. Group B received only general recommendations about home-based physical activities.RESULTS Eighty-five KTRs completed the study(Group A, n = 44; Group B, n = 41). After 12 mo, renal function remained stable in both groups. Group A significantly increased maximum workload(+13 W, P = 0.0003), V'O2 peak(+3.1 mL/kg per minute, P = 0.0099), muscular strength in plantar flexor(+12 kg, P = 0.0368), height in the countermovement jump(+1.9 cm, P = 0.0293) and decreased in Body Mass Index(-0.5 kg/m^2, P = 0.0013). HRQo L significantly improved in physical function(P = 0.0019), physical-role limitations(P = 0.0321) and social functioning scales(P = 0.0346). Noimprovements were found in Group B.CONCLUSION Twelve-month of supervised aerobic and resistance training improves the physiological variables related to physical fitness and cardiovascular risks without consequences on renal function. Recommendations alone are not sufficient to induce changes in exercise capacity of KTRs. Our study is an example of collaborative working between transplant centres, sports medicine and exercise facilities.
文摘The daily evaluation of the life style is funda- mental for the “exercise as prescription” to re- duce the cardiovascular risks factors. The reg- istration by an accelerometer can identify active from inactive subjects. The aim of the present study is to verify, in a small cohort of subjects at high risk level (obese–hypertensive), the health outcomes. A group of 22 subjects were evalu- ated by the questionnaire and also by an accel- erometer positioned on belt for 5 days to estab- lish the daily Physical Activity Level (PAL).The anthropometrics parameters, Body Mass Index (BMI), Waist Circumference, Hip Circumference, Fat Mass, Free Fat Mass, Total Body–Intracellular and Extracellular Water and Phase Angle (PA) were measured at the beginning and after 3 months of regular exercise. The amount of the exercise prescribed for three months and at least 3 times in a weak, was determined by the Cardiopulmonary test at the 60% of the VO2. Sta-tistical analysis included T-Student test for paired data with a significance at P < 0.05value. Respect of the questionnaire the accelerometer report showed a predominantly inactive life style (PAL = 1.49 ± 0.13). After three months the BMI was significantly reduced in all (p < 0.05) and in addi-tion a trend toward a reduction was also observed for Fatty Mass and for the body composition parameters. The employment of the accelerometer is therefore associated to an improvement of the parameters strongly related with the cardiovascular risk. The results obtained are suggestive for an educational role of this tool in subjects at high risk level.
文摘The Aerobic Threshold (AerT), is an aged cardiovascular parameter not commonly used to evaluate the heart’s performance in athletes. It indirectly evaluated by ventilator parameters during Cardio Pulmonary Test (CPT). Considering that” exercise as prescription therapy “for the diseases, includes training normally established around at the 40% of the peak VO2, this parameter could be taken in care as initial level for the effort prescribed. The aim of the study was to estimate the behavior of the AerT and also Anaerobic Threshold (AT), VO2max in sedentary people. A group of athletes coming from different sports at the same and highest dynamic component were enrolled as control. A group of 41 athletes (16 soccer, 10 basket and 15 cyclists) and 9 healthy subjects were submitted to a CPT. The AerT, AT (assessed by Vslope method) and VO2max were evaluated. The statistical analysis was performed with T student test (P < 0.05 significant). As expected in sedentary all the values were lower than athletes, however for Aer T value appears to be not significantly inferior respect of this one, with the exclusion of the comparison with the cyclists. In sedentary the AerT measure seems to give additional information in evaluating the cardiovascular performance. The VO2max and AT remain the main parameters in defining the athletes performance. Therefore we cannot exclude any further utility of the AerT in normal subject but regularly trained.
文摘Objective: Bicuspid Aortic Valve (BAV) is normally asymptomatic for a long time in both the general population and regularlytrained athletes. The study aimed to evaluate the role of physical stress echocardiography in early identification of any possible dissimilarities in the Left Ventricle (LV) performance and the valve functioning of asymptomatic BAV athletes as compared to the Tricuspid Aortic Valve (TAV) athletes. Design: Data were collected for BAV and TAV athletes from echocardographic examinations to evaluate any possible differences between them. Setting: Sport Medicine Center University of FlorenceItaly. Participants: 66 male BAV athletes and 45 TAV athletes Assessment of risk factors: decrease in LV performance and aortic valve dysfunction during stress test. Main outcome measures: Measure of the standard echocardiographic parameters. Comparison of LV Ejection Fraction (EF) and Aortic Peak Flow Velocity (APFV) data in the two groups at rest and after stress. Results: At rest, values were normal in both groups, although LV systolic diameters tended to be higher in BAV. After physical effort, APFV and EF showed a significant increase in both groups, and for the former the values were at the upper limits in BAV (2.55 m/s BAV 2.12 m/s TAV). Conclusions: The data confirm normal LV performance in asymptomatic BAV athletes. Considering the tendency of this group to show slight enhancement of both APFV and LV dimensions in this group periodical evaluation with physical stress echography might be proposed as a followup procedure for early detection of any additional effect of physical exercise.