Nipah virus (NiV), a zoonotic paramyxovirus belonging to the genus Henipavirus, is classified as a Biosafety Level-4 pathogen based on its high pathogenicity in humans and the lack of available vaccines or therapeutic...Nipah virus (NiV), a zoonotic paramyxovirus belonging to the genus Henipavirus, is classified as a Biosafety Level-4 pathogen based on its high pathogenicity in humans and the lack of available vaccines or therapeutics. Since its initial emergence in 1998 in Malaysia, this virus has become a great threat to domestic animals and humans. Sporadic outbreaks and person-to-person transmission over the past two decades have resulted in hundreds of human fatalities. Epidemiological surveys have shown that NiV is distributed in Asia, Africa, and the South Pacific Ocean, and is transmitted by its natural reservoir, Pteropid bats. Numerous efforts have been made to analyze viral protein function and structure to develop feasible strategies for drug design. Increasing surveillance and preventative measures for the viral infectious disease are urgently needed.展开更多
Dear Editor,African swine fever(ASF)is one of the most pathogenic viral diseases in pigs caused by African swine fever virus(ASFV).The fatality rate is almost 100%,which brings huge economic losses to the hog industry...Dear Editor,African swine fever(ASF)is one of the most pathogenic viral diseases in pigs caused by African swine fever virus(ASFV).The fatality rate is almost 100%,which brings huge economic losses to the hog industry in countries with epiepidemics(Galindo and Alonso,2017).China was the first Asian country to have an ASF epidemic,and it spread quickly across the country after the first epidemic was re・ported in August 2018(Ge et al.,2018).After that,Mongolia,Vietnam,Cambodia and North Korea also reported on the ASF epidemic in succession(OIE,2019).展开更多
Dear Editor,Coronavirus disease 2019(COVID-19)is still the most emerging infectious disease plaguing human society,and secondary bacterial infection is one of the major causes of its progression to severe illness and ...Dear Editor,Coronavirus disease 2019(COVID-19)is still the most emerging infectious disease plaguing human society,and secondary bacterial infection is one of the major causes of its progression to severe illness and death.In this study,pharyngeal swabs were collected from patients with COVID-19 and influenza,and the microbiome landscape of the upper respiratory tract(URT)of both patients was compared,revealing disease-specific associated microorganisms.展开更多
Dear Editor,It has been more than 1 year since China reported the first case of African swine fever (ASF) infection in August2018, and the epidemic situation remains severe (China News Service 2019). According to repo...Dear Editor,It has been more than 1 year since China reported the first case of African swine fever (ASF) infection in August2018, and the epidemic situation remains severe (China News Service 2019). According to reports from the Ministry of Agriculture and Rural Affairs, China has reported 160 cases of ASF, which resulted in nearly 1.2 million pigs being killed, as of November 21, 2019 (China News Service 2019).展开更多
Dear Editor,African swine fever(ASF)is a severe haemorrhagic fever in domestic pigs and wild boar with extremely high mortality rate.It is cataloged as a notifiable disease by the World Organization for Animal Health(...Dear Editor,African swine fever(ASF)is a severe haemorrhagic fever in domestic pigs and wild boar with extremely high mortality rate.It is cataloged as a notifiable disease by the World Organization for Animal Health(OIE).The etiological agent that causes the highly lethal disease is the African swine fever virus(ASFV)(Sanchez-Vizcaino) et al.展开更多
基金supported by National Key Research and Development Program(2016YFC1200800)Advanced Customer Cultivation Project of Wuhan National Biosafety Laboratory,Chinese Academy of Sciences
文摘Nipah virus (NiV), a zoonotic paramyxovirus belonging to the genus Henipavirus, is classified as a Biosafety Level-4 pathogen based on its high pathogenicity in humans and the lack of available vaccines or therapeutics. Since its initial emergence in 1998 in Malaysia, this virus has become a great threat to domestic animals and humans. Sporadic outbreaks and person-to-person transmission over the past two decades have resulted in hundreds of human fatalities. Epidemiological surveys have shown that NiV is distributed in Asia, Africa, and the South Pacific Ocean, and is transmitted by its natural reservoir, Pteropid bats. Numerous efforts have been made to analyze viral protein function and structure to develop feasible strategies for drug design. Increasing surveillance and preventative measures for the viral infectious disease are urgently needed.
基金supported by the National Key R&D Program of China (2016YFC1200800 & 2018YFC0840402)Research Project of African Swine Fever of Chinese Academy of Sciences (KJZD-SWL06)+2 种基金China Mega-Project for Infectious Disease (2017ZX10103005-005)the State Key Laboratory of Veterinary Biotechnology Research Fund (SKLVBF201902)supported by Youth Innovation Promotion Association of CAS (2019091)
文摘Dear Editor,African swine fever(ASF)is one of the most pathogenic viral diseases in pigs caused by African swine fever virus(ASFV).The fatality rate is almost 100%,which brings huge economic losses to the hog industry in countries with epiepidemics(Galindo and Alonso,2017).China was the first Asian country to have an ASF epidemic,and it spread quickly across the country after the first epidemic was re・ported in August 2018(Ge et al.,2018).After that,Mongolia,Vietnam,Cambodia and North Korea also reported on the ASF epidemic in succession(OIE,2019).
基金supported by the National Natural Science Foundation of China(81961138013,31970174)the National Key Research and Development Program of China(2018YFC1603803,2017ZX10103005-005)the Key Program of Chinese Academy of Sciences(CAS)(KJZD-SW-L11)。
文摘Dear Editor,Coronavirus disease 2019(COVID-19)is still the most emerging infectious disease plaguing human society,and secondary bacterial infection is one of the major causes of its progression to severe illness and death.In this study,pharyngeal swabs were collected from patients with COVID-19 and influenza,and the microbiome landscape of the upper respiratory tract(URT)of both patients was compared,revealing disease-specific associated microorganisms.
基金supported by the Research Project of African Swine Fever of Chinese Academy of Sciences (KJZD-SWL06)the National Natural Science Foundation of China (31941015)+3 种基金the National Key R&D Program of China (2016YFC1200800&2018YFC0840402)the China Mega-Project for Infectious Disease(2017ZX10103005-005)the State Key Laboratory of Veterinary Biotechnology Research Fund (SKLVBF201902)supported by Youth Innovation Promotion Association of CAS (2019091)。
文摘Dear Editor,It has been more than 1 year since China reported the first case of African swine fever (ASF) infection in August2018, and the epidemic situation remains severe (China News Service 2019). According to reports from the Ministry of Agriculture and Rural Affairs, China has reported 160 cases of ASF, which resulted in nearly 1.2 million pigs being killed, as of November 21, 2019 (China News Service 2019).
基金supported by grants from the National Key Research and Development Program of China(2018YFC1603803,2018YFC0840402 and 2016YFC1200800)the Research Project of African Swine Fever of Chinese Academy of Sciences(KJZD-SW-L06)
文摘Dear Editor,African swine fever(ASF)is a severe haemorrhagic fever in domestic pigs and wild boar with extremely high mortality rate.It is cataloged as a notifiable disease by the World Organization for Animal Health(OIE).The etiological agent that causes the highly lethal disease is the African swine fever virus(ASFV)(Sanchez-Vizcaino) et al.
