Cocamidopropyl hydroxyl sulfobetaine(CHSB)is one of the most promising foaming agents for high-salinity reservoirs because the salt in place facilitates its foam stability,even with salinity as high as 2×10^(5)mg...Cocamidopropyl hydroxyl sulfobetaine(CHSB)is one of the most promising foaming agents for high-salinity reservoirs because the salt in place facilitates its foam stability,even with salinity as high as 2×10^(5)mg/L.However,the synergistic effects between CHSB and salt have not been fully understood.This study utilized bulk foam tests and thin-film interferometry to comprehensively investigate the macroscopic and microscopic decay processes of CHSB foams with NaCl concentrations ranging from 2.3×10^(4)to 2.1×10^(5)mg/L.We focused on the dilatational viscoelasticity and dynamic thin-film thickness to elucidate the high-salinity-enhanced foam stability.The increase in dilatational viscoelasticity and supramolecular oscillating structural force(Π_(OS))with salinity dominated the superior stability of CHSB foam.With increasing salinity,more CHSB molecules accumulated on the surface with a lower diffusion rate,leading to high dilatational moduli and surface elasticity,thus decelerating coarsening and coalescence.Meanwhile,the number density of micelles in the thin film increased with salinity,resulting in increasedΠOS.Consequently,the energy barrier for stepwise thinning intensified,and the thin-film drainage slowed.This work conduces to understand the mechanisms behind the pronounced stability of betaine foam and can promote the widespread application of foam in harsh reservoirs.展开更多
The dynamic traveling salesman problem(DTSP)is significant in logistics distribution in real-world applications in smart cities,but it is uncertain and difficult to solve.This paper proposes a scheme library-based ant...The dynamic traveling salesman problem(DTSP)is significant in logistics distribution in real-world applications in smart cities,but it is uncertain and difficult to solve.This paper proposes a scheme library-based ant colony optimization(ACO)with a two-optimization(2-opt)strategy to solve the DTSP efficiently.The work is novel and contributes to three aspects:problemmodel,optimization framework,and algorithmdesign.Firstly,in the problem model,traditional DTSP models often consider the change of travel distance between two nodes over time,while this paper focuses on a special DTSP model in that the node locations change dynamically over time.Secondly,in the optimization framework,the ACO algorithm is carried out in an offline optimization and online application framework to efficiently reuse the historical information to help fast respond to the dynamic environment.The framework of offline optimization and online application is proposed due to the fact that the environmental change inDTSPis caused by the change of node location,and therefore the newenvironment is somehowsimilar to certain previous environments.This way,in the offline optimization,the solutions for possible environmental changes are optimized in advance,and are stored in a mode scheme library.In the online application,when an environmental change is detected,the candidate solutions stored in the mode scheme library are reused via ACO to improve search efficiency and reduce computational complexity.Thirdly,in the algorithm design,the ACO cooperates with the 2-opt strategy to enhance search efficiency.To evaluate the performance of ACO with 2-opt,we design two challenging DTSP cases with up to 200 and 1379 nodes and compare them with other ACO and genetic algorithms.The experimental results show that ACO with 2-opt can solve the DTSPs effectively.展开更多
Cellular senescence and chronic inflammation in response to aging are considered to be indicators of brain aging;they have a great impact on the aging process and are the main risk factors for neurodegeneration.Review...Cellular senescence and chronic inflammation in response to aging are considered to be indicators of brain aging;they have a great impact on the aging process and are the main risk factors for neurodegeneration.Reviewing the microglial response to aging and neuroinflammation in neurodegenerative diseases will help understand the importance of microglia in neurodegenerative diseases.This review describes the origin and function of microglia and focuses on the role of different states of the microglial response to aging and chronic inflammation on the occurrence and development of neurodegenerative diseases,including Alzheimer's disease,Huntington's chorea,and Parkinson's disease.This review also describes the potential benefits of treating neurodegenerative diseases by modulating changes in microglial states.Therefore,inducing a shift from the neurotoxic to neuroprotective microglial state in neurodegenerative diseases induced by aging and chronic inflammation holds promise for the treatment of neurodegenerative diseases in the future.展开更多
The poor compatibility of ester electrolytes with lithium metal anode severely limits its use in high voltage lithium metal batteries(LMBs).In this work,a bidentate solvent 1,2-diethoxyethane(DEE) is introduced into e...The poor compatibility of ester electrolytes with lithium metal anode severely limits its use in high voltage lithium metal batteries(LMBs).In this work,a bidentate solvent 1,2-diethoxyethane(DEE) is introduced into ester electrolyte to regulate the ion-dipole interactions to enhance the solubility of LiNO_(3),which enables compatibility with Li anode and maintains the high voltage cathode stability.In the designed electrolyte,the steric effect of DEE facilitates the participation of NO_(3)^(-)and PF_6^(-)anions in the Li^(+) solvation structure,thus promoting the generation of inorganic-rich solid electrolyte interphase(SEI).And the low viscosity of DEE also ensures that the ester electrolyte poses good interracial wettability.As a result,our designed electrolyte enables the high-loading Li‖NCM622 and Li‖NCM811(^(3) mA h cm^(-2)) full cells to achieve stable cycling over 200 cycles,8 times longer than that of a conventional ester electrolyte.This work suggests that regulation of intermolecular interactions in conventional ester electrolytes is a scalable and effective approach to achieve excellent electrochemical performance of LMBs.展开更多
The flexed frustules in pennate diatoms are usually associated with monoraphid diatoms. Interestingly, we found a biraphid diatom species with flexed frustules in an offshore intertidal beach environment on Weizhou Is...The flexed frustules in pennate diatoms are usually associated with monoraphid diatoms. Interestingly, we found a biraphid diatom species with flexed frustules in an offshore intertidal beach environment on Weizhou Island,Beihai City, Guangxi Zhuang Autonomous Region, China. Therefore, based on morphological characteristics, we described a new genus of diatoms Yuzaoea sinensis gen. et sp. nov. CH Li, HH Liu, YH Gao & CP Chen. The frustule of this genus is characterized by heterogeneous frustule with one concave valve and one convex valve,complete raphe on both valves, straight and moderately eccentric raphe, uniseriate striae and girdle bands with a single row of areolae. The most identifying feature of this genus was the flexed frustule, which is rare in biraphid diatoms and common in monoraphid diatoms. We compared the morphometric characteristics of genus Yuzaoea with genus Rhoikoneis and several genera within the family Rhoicospheniaceae, including Rhoicosphenia,Campylopyxis, and Cuneolus. Phylogenetic analyses based on SSU rRNA and rbc L showed that the genus Yuzaoea was the sister group to the clade of Rhoicosphenia with a high support value(bootstrap values = 100%), and the clade “Yuzaoea+Rhoicosphenia” was sister to the clade of monoraphid diatoms, in which the genera Achnanthidium, Planothidium and some Cocconeis with high support values(bootstrap = 100%).Morphologically, the genus Yuzaoea shares many morphological features with monoraphid diatoms like genera Achnanthidium and Planothidium and the members within the Rhoicospheniaceae. Therefore, based on a combined morphological studies and phylogenetic results we suggested that this branch may represented the evolution of one kind monoraphid diatoms, from biraphid diatoms(e.g. genus Yuzaoea), to incompleted biraphid diatoms(e.g. genera Rhoicosphenia, Campylopyxis), to monoraphid diatoms(e.g. genera Achnanthidium and Planothidium).展开更多
Purpose–The electromechanical brake system is leading the latest development trend in railway braking technology.The tolerance stack-up generated during the assembly and production process catalyzes the slight geomet...Purpose–The electromechanical brake system is leading the latest development trend in railway braking technology.The tolerance stack-up generated during the assembly and production process catalyzes the slight geometric dimensioning and tolerancing between the motor stator and rotor inside the electromechanical cylinder.The tolerance leads to imprecise brake control,so it is necessary to diagnose the fault of the motor in the fully assembled electromechanical brake system.This paper aims to present improved variational mode decomposition(VMD)algorithm,which endeavors to elucidate and push the boundaries of mechanical synchronicity problems within the realm of the electromechanical brake system.Design/methodology/approach–The VMD algorithm plays a pivotal role in the preliminary phase,employing mode decomposition techniques to decompose the motor speed signals.Afterward,the error energy algorithm precision is utilized to extract abnormal features,leveraging the practical intrinsic mode functions,eliminating extraneous noise and enhancing the signal’s fidelity.This refined signal then becomes the basis for fault analysis.In the analytical step,the cepstrum is employed to calculate the formant and envelope of the reconstructed signal.By scrutinizing the formant and envelope,the fault point within the electromechanical brake system is precisely identified,contributing to a sophisticated and accurate fault diagnosis.Findings–This paper innovatively uses the VMD algorithm for the modal decomposition of electromechanical brake(EMB)motor speed signals and combines it with the error energy algorithm to achieve abnormal feature extraction.The signal is reconstructed according to the effective intrinsic mode functions(IMFS)component of removing noise,and the formant and envelope are calculated by cepstrum to locate the fault point.Experiments show that the empirical mode decomposition(EMD)algorithm can effectively decompose the original speed signal.After feature extraction,signal enhancement and fault identification,the motor mechanical fault point can be accurately located.This fault diagnosis method is an effective fault diagnosis algorithm suitable for EMB systems.Originality/value–By using this improved VMD algorithm,the electromechanical brake system can precisely identify the rotational anomaly of the motor.This method can offer an online diagnosis analysis function during operation and contribute to an automated factory inspection strategy while parts are assembled.Compared with the conventional motor diagnosis method,this improved VMD algorithm can eliminate the need for additional acceleration sensors and save hardware costs.Moreover,the accumulation of online detection functions helps improve the reliability of train electromechanical braking systems.展开更多
Precision grinding is a key process for realizing the use of large-aperture aspherical optical elements in laser nuclear fusion devices,large-aperture astronomical telescopes,and high-resolution space cameras.In this ...Precision grinding is a key process for realizing the use of large-aperture aspherical optical elements in laser nuclear fusion devices,large-aperture astronomical telescopes,and high-resolution space cameras.In this study,the arc envelope grinding process of large-aperture aspherical optics is investigated using a CM1500 precision grinding machine with a maximum machinable diameter ofΦ1500 mm.The form error of the aspherical workpiece induced by wheel setting errors is analytically modeled for both parallel and cross grinding.Results show that the form error is more sensitive to the wheel setting error along the feed direction than that along the lateral direction.It is a bilinear function of the feed-direction wheel setting error and the distance to the optical axis.Based on the error function above,a method to determine the wheel setting error is proposed.Subsequently,grinding tests are performed with the wheels aligned accurately.Using a newly proposed partial error compensation method with an appropriate compensation factor,a form error of 3.4μm peak-to-valley(PV)for aΦ400 mm elliptical K9 glass surface is achieved.展开更多
In this study,a hydrophobic material,ethylcellulose,which was used as its aqueous suspension Surelease^(®),was combined with a swelling agent as the swelling layer to prepare delayed-release pellets for Danshensu...In this study,a hydrophobic material,ethylcellulose,which was used as its aqueous suspension Surelease^(®),was combined with a swelling agent as the swelling layer to prepare delayed-release pellets for Danshensu,which is a hydrophilic drug with low MW.A rupturable,delayed-release pellet consists of a drug core,a swelling layer containing a swelling agent(cross-linked sodium carboxymethyl cellulose)with a hydrophobic agent(Surelease^(®)),and a controlled layer composed by an insoluble,water-permeable polymeric coating(aqueous ethylcellulose dispersions)was developed in a fluidised bed.Results showed that blending Surelease^(®)into the swelling layer could effectively extend the release of Danshensu from the pellets,which may be attributed to the slowed swelling rate by reduction of water penetration and improvement of mechanical integrity of the swelling layer.Drug in the delayed pellets showed sustained release in beagle dogs after oral administration with comparable in-vivo exposure to the uncoated drug pellets.In conclusion,blends of hydrophobic and swelling agents in the swelling layer in doublemembrane pellets could achieve a delayed drug-release profile in vitro,as well as delayed and sustained absorption in vivo for highly soluble,low-MW drug.The present study highlighted the potential use of a delayed-release system for other hydrophilic,low-MW drugs to meet the formulation requirements for chronopharmacological diseases.展开更多
The removal of metallic impurities from off-grade copper concentrate was investigated in alkaline solution with H2O2. The analysis results of XRD and SEM-EDS revealed the oxidative mechanisms of all sulfides. The infl...The removal of metallic impurities from off-grade copper concentrate was investigated in alkaline solution with H2O2. The analysis results of XRD and SEM-EDS revealed the oxidative mechanisms of all sulfides. The influence of various parameters of alkaline leaching were investigated including concentrations of sodium hydroxide and hydrogen peroxide, liquid to solid ratio, leaching time and temperature. The results showed that the removal rate of Mo, As and Zn were increased with increasing leaching time and H2O2 concentration, and that the removal rate of Mo, As and Zn were firstly increased and then slightly decreased with increasing liquid to solid ratio, temperature and NaOH concentration, respectively. More than 95% Mo, 94% As, and 94 % Zn are removed from the off-grade concentrate under the optimum conditions, while only 1.7% Cu is dissolved. These optimum conditions were sodium hydroxide 1.5 mol/L, hydrogen peroxide 1.0 mol/L, temperature 50°C, liquid to solid ratio 5/1 mL/g and leaching time 5 h.展开更多
Objective:To study the effect of Danhong injection on neuroendocrine molecules and ventricular remodeling in patients with ischemic cardiomyopathy heart failure.Methods: 80 cases of patients with ischemic cardiomyopat...Objective:To study the effect of Danhong injection on neuroendocrine molecules and ventricular remodeling in patients with ischemic cardiomyopathy heart failure.Methods: 80 cases of patients with ischemic cardiomyopathy heart failure who were treated in our hospital between March 2014 and December 2016 were collected and divided into control group (n=40) and observation group (n=40) according to random number table. The control group received regular treatment, the observation group received regular + Danhong injection treatment, and both therapies lasted for 14 d a course, two sessions. Serum contents of neuroendocrine molecules and ventricular remodeling-related indexes, Doppler ultrasonic ventricular remodeling parameter levels, and so on were compared between two groups of patients before and after treatment.Results: Before treatment, serum contents of neuroendocrine molecules and ventricular remodeling-related indexes as well as Doppler ultrasonic ventricular remodeling parameter levels were not statistically different between two groups of patients. After treatment, serum neuroendocrine molecules NT-proBNP, ANP, AngⅡ, ALD and NE contents of observation group were lower than those of control group, serum ventricular remodeling indexes TGF-β1, NF-κB, CysC and FGF23 contents were lower than those of control group, and ultrasonic ventricular remodeling parameters LVMI, LVRI, RVEDV and RVESV levels were lower than those of control group.Conclusion: Adjuvant Danhong injection therapy helps optimize the neuroendocrine molecule contents and inhibit the ventricular remodeling process in patients with ischemic cardiomyopathy heart failure.展开更多
Expert consensus proposes an emergency treatment protocol for portal hypertension bleeding. Herein, the emergency treatment procedures, which include first aid, medical, interventional, and surgical treatments, are de...Expert consensus proposes an emergency treatment protocol for portal hypertension bleeding. Herein, the emergency treatment procedures, which include first aid, medical, interventional, and surgical treatments, are described. In addition, the indications, contraindications, operating norms, precautions, and prevention of complications of portal hypertension are described to optimize the first aid process.展开更多
The response of phytoplankton and its satellite bacteria to various concentrations(0.01%-10%v/v)of ethanol is studied.To elucidate the effect of ethanol,single-strains of phytoplankton(SSP)culture,pure strains of sate...The response of phytoplankton and its satellite bacteria to various concentrations(0.01%-10%v/v)of ethanol is studied.To elucidate the effect of ethanol,single-strains of phytoplankton(SSP)culture,pure strains of satellite bacteria isolated from nonaxenic SSP cultures,and Escherichia coli were screened.Results indicate that ethanol could promote the growth and photo synthetic efficiency(F_(v)/F_(m))of S SP at 0.01%and the growth of satellite bacteria at 0.01%-1%.Nevertheless,ethanol inhibited the growth and F_(v)/F_(m)of SSP at 0.1%-1%,and killed bacteria and SSP at 10% concentration.Further investigation on a satellite bacterium(Mameliella alba)revealed that ethanol promotes growth by serving as a growth stimulant rather than a metabolic carbon source.The 16 S rRNA gene amplicon indicated that all nonaxenic S SP cultures harbor distinct satellite bacteria communities where the SSP culture of Skeletonema costatum,Phaeodactylum tricornutum,and Dunaliella bardawil were dominated by bacteria genera of Marivita(~80%),Dinoroseobacter(~47%),and Halomonas(~87%),respectively,indicating that every SSP cultures have their own distinct satellite bacterial community.The bacteria family Rhodobacteraceae was dominant in the two marine diatoms,whereas Halomonadaceae was dominant in the saline green microalga.Compared to their respective controls,the supply of 0.5% ethanol to SSP cultures promoted the growth of the satellite bacteria but did not cause a significant difference in species composition of satellite bacteria.Therefore,a low concentration of ethanol can promote the growth of bacteria in a non-selective way.This study enriched our knowledge about the effect of ethanol on aquatic microbes and provided a baseline for basic and applied biotechnological re search in the aquatic environment in the future.展开更多
The increasing severity of ground subsidence,ground fissure and other disasters caused by the excessive exploitation of deep underground resources has highlighted the pressing need for effective management.A significa...The increasing severity of ground subsidence,ground fissure and other disasters caused by the excessive exploitation of deep underground resources has highlighted the pressing need for effective management.A significant contributing factor to the challenges faced is the inadequacy of existing soil mechanics experimental instruments in providing effective indicators,creating a bottleneck in comprehensively understanding the mechanisms of land subsidence.It is urgent to develop a multi-field and multi-functional soil mechanics experimental system to address this issue.Based soil mechanics theories,the existing manufacturing capabilities of triaxial apparatus and the practical demands of the test system,a set of multi-field coupled high-pressure triaxial system is developed tailored for testing deep soils(at depths of approximately 3000 m)and soft rock.This system incorporates specialized design elements such as high-pressure chamber and horizontal deformation testing devices.In addition to the conventional triaxial tester functions,its distinctive feature encompass a horizontal deformation tracking measuring device,a water release testing device and temperature control device for the sample.This ensemble facilitates testing of horizontal and vertical deformation water release and other parameters of samples under a specified stress conditions,at constant or varying temperature ranging from-40℃–90℃.The accuracy of the tested parameters meets the requirements of relevant current specifications.The test system not only provides scientifically robust data for revealing the deformation and failure mechanism of soil subjected to extreme temperature,but also offers critical data support for major engineering projects,deep exploration and mitigation efforts related to soil deformation-induced disaster.展开更多
<strong>Objective: </strong>This study aimed to clarify the death characteristics of esophageal cancer in Inner Mongolia and the population distribution with various education levels. <strong>Methods...<strong>Objective: </strong>This study aimed to clarify the death characteristics of esophageal cancer in Inner Mongolia and the population distribution with various education levels. <strong>Methods:</strong> The mortality rate of esophageal cancer was calculated using the monitoring point of Death Registry System in Inner Mongolia from 2009 to 2015. The gender, age, region, ethnicity at two education levels of percentage were calculated and the <em>χ</em><sup>2</sup> test was executed. <strong>Result:</strong> The mortality rate of esophageal cancer was 10.10/105, China Adjustment Mortality was 10.97/10<sup>5</sup>, World Adjustment Mortality was 9.08/10<sup>5</sup> in Inner Mongolia. The death of esophageal cancer showed statistical significance at two educational levels (P < 0.05). High school and below accounted for 93.9% at the education level, and above high school accounted for 3.5%. In addition, there were significant differences in the percentage of death by gender, age and region at two educational levels (P < 0.05). <strong>Conclusion:</strong> Education level has a certain relation with the death of esophageal cancer. To improve the health level, health education plans can be formulated according to esophageal cancer prevention relevant policy with different education levels.展开更多
基金The authors would like to be grateful for the financial support of National Natural Science Foundation of China(No.51904256).
文摘Cocamidopropyl hydroxyl sulfobetaine(CHSB)is one of the most promising foaming agents for high-salinity reservoirs because the salt in place facilitates its foam stability,even with salinity as high as 2×10^(5)mg/L.However,the synergistic effects between CHSB and salt have not been fully understood.This study utilized bulk foam tests and thin-film interferometry to comprehensively investigate the macroscopic and microscopic decay processes of CHSB foams with NaCl concentrations ranging from 2.3×10^(4)to 2.1×10^(5)mg/L.We focused on the dilatational viscoelasticity and dynamic thin-film thickness to elucidate the high-salinity-enhanced foam stability.The increase in dilatational viscoelasticity and supramolecular oscillating structural force(Π_(OS))with salinity dominated the superior stability of CHSB foam.With increasing salinity,more CHSB molecules accumulated on the surface with a lower diffusion rate,leading to high dilatational moduli and surface elasticity,thus decelerating coarsening and coalescence.Meanwhile,the number density of micelles in the thin film increased with salinity,resulting in increasedΠOS.Consequently,the energy barrier for stepwise thinning intensified,and the thin-film drainage slowed.This work conduces to understand the mechanisms behind the pronounced stability of betaine foam and can promote the widespread application of foam in harsh reservoirs.
基金supported in part by the National Research Foundation of Korea (NRF-2021H1D3A2A01082705).
文摘The dynamic traveling salesman problem(DTSP)is significant in logistics distribution in real-world applications in smart cities,but it is uncertain and difficult to solve.This paper proposes a scheme library-based ant colony optimization(ACO)with a two-optimization(2-opt)strategy to solve the DTSP efficiently.The work is novel and contributes to three aspects:problemmodel,optimization framework,and algorithmdesign.Firstly,in the problem model,traditional DTSP models often consider the change of travel distance between two nodes over time,while this paper focuses on a special DTSP model in that the node locations change dynamically over time.Secondly,in the optimization framework,the ACO algorithm is carried out in an offline optimization and online application framework to efficiently reuse the historical information to help fast respond to the dynamic environment.The framework of offline optimization and online application is proposed due to the fact that the environmental change inDTSPis caused by the change of node location,and therefore the newenvironment is somehowsimilar to certain previous environments.This way,in the offline optimization,the solutions for possible environmental changes are optimized in advance,and are stored in a mode scheme library.In the online application,when an environmental change is detected,the candidate solutions stored in the mode scheme library are reused via ACO to improve search efficiency and reduce computational complexity.Thirdly,in the algorithm design,the ACO cooperates with the 2-opt strategy to enhance search efficiency.To evaluate the performance of ACO with 2-opt,we design two challenging DTSP cases with up to 200 and 1379 nodes and compare them with other ACO and genetic algorithms.The experimental results show that ACO with 2-opt can solve the DTSPs effectively.
基金supported partly by the National Natural Science Foundation of China,Nos.32161143021 and 81271410the Natural Science Foundation of Henan Province of China,No.182300410313(all to JW)。
文摘Cellular senescence and chronic inflammation in response to aging are considered to be indicators of brain aging;they have a great impact on the aging process and are the main risk factors for neurodegeneration.Reviewing the microglial response to aging and neuroinflammation in neurodegenerative diseases will help understand the importance of microglia in neurodegenerative diseases.This review describes the origin and function of microglia and focuses on the role of different states of the microglial response to aging and chronic inflammation on the occurrence and development of neurodegenerative diseases,including Alzheimer's disease,Huntington's chorea,and Parkinson's disease.This review also describes the potential benefits of treating neurodegenerative diseases by modulating changes in microglial states.Therefore,inducing a shift from the neurotoxic to neuroprotective microglial state in neurodegenerative diseases induced by aging and chronic inflammation holds promise for the treatment of neurodegenerative diseases in the future.
基金financially National Natural Science Foundation of China (Grant No. 22209134)Fundamental Research Funds for the Central Universities, Southwest Minzu University (Grant No. ZYN2023003)+1 种基金Sichuan Science and Technology Program (Grant No. 2024NSFSC1155)Fundamental Research Funds for the Central Universities, Southwest Jiaotong University (Grant No. 2682023CX005)。
文摘The poor compatibility of ester electrolytes with lithium metal anode severely limits its use in high voltage lithium metal batteries(LMBs).In this work,a bidentate solvent 1,2-diethoxyethane(DEE) is introduced into ester electrolyte to regulate the ion-dipole interactions to enhance the solubility of LiNO_(3),which enables compatibility with Li anode and maintains the high voltage cathode stability.In the designed electrolyte,the steric effect of DEE facilitates the participation of NO_(3)^(-)and PF_6^(-)anions in the Li^(+) solvation structure,thus promoting the generation of inorganic-rich solid electrolyte interphase(SEI).And the low viscosity of DEE also ensures that the ester electrolyte poses good interracial wettability.As a result,our designed electrolyte enables the high-loading Li‖NCM622 and Li‖NCM811(^(3) mA h cm^(-2)) full cells to achieve stable cycling over 200 cycles,8 times longer than that of a conventional ester electrolyte.This work suggests that regulation of intermolecular interactions in conventional ester electrolytes is a scalable and effective approach to achieve excellent electrochemical performance of LMBs.
基金The National Key Research and Development Program of China under contract No. 2022YFC3105404the Natural Science Foundation of China under contract Nos 42076114, 41776124the Natural Science Foundation of Xiamen under contract No.3502Z20227173。
文摘The flexed frustules in pennate diatoms are usually associated with monoraphid diatoms. Interestingly, we found a biraphid diatom species with flexed frustules in an offshore intertidal beach environment on Weizhou Island,Beihai City, Guangxi Zhuang Autonomous Region, China. Therefore, based on morphological characteristics, we described a new genus of diatoms Yuzaoea sinensis gen. et sp. nov. CH Li, HH Liu, YH Gao & CP Chen. The frustule of this genus is characterized by heterogeneous frustule with one concave valve and one convex valve,complete raphe on both valves, straight and moderately eccentric raphe, uniseriate striae and girdle bands with a single row of areolae. The most identifying feature of this genus was the flexed frustule, which is rare in biraphid diatoms and common in monoraphid diatoms. We compared the morphometric characteristics of genus Yuzaoea with genus Rhoikoneis and several genera within the family Rhoicospheniaceae, including Rhoicosphenia,Campylopyxis, and Cuneolus. Phylogenetic analyses based on SSU rRNA and rbc L showed that the genus Yuzaoea was the sister group to the clade of Rhoicosphenia with a high support value(bootstrap values = 100%), and the clade “Yuzaoea+Rhoicosphenia” was sister to the clade of monoraphid diatoms, in which the genera Achnanthidium, Planothidium and some Cocconeis with high support values(bootstrap = 100%).Morphologically, the genus Yuzaoea shares many morphological features with monoraphid diatoms like genera Achnanthidium and Planothidium and the members within the Rhoicospheniaceae. Therefore, based on a combined morphological studies and phylogenetic results we suggested that this branch may represented the evolution of one kind monoraphid diatoms, from biraphid diatoms(e.g. genus Yuzaoea), to incompleted biraphid diatoms(e.g. genera Rhoicosphenia, Campylopyxis), to monoraphid diatoms(e.g. genera Achnanthidium and Planothidium).
基金funded by the Science Foundation of China Academy of Railway Science,grant number 2020YJ175.
文摘Purpose–The electromechanical brake system is leading the latest development trend in railway braking technology.The tolerance stack-up generated during the assembly and production process catalyzes the slight geometric dimensioning and tolerancing between the motor stator and rotor inside the electromechanical cylinder.The tolerance leads to imprecise brake control,so it is necessary to diagnose the fault of the motor in the fully assembled electromechanical brake system.This paper aims to present improved variational mode decomposition(VMD)algorithm,which endeavors to elucidate and push the boundaries of mechanical synchronicity problems within the realm of the electromechanical brake system.Design/methodology/approach–The VMD algorithm plays a pivotal role in the preliminary phase,employing mode decomposition techniques to decompose the motor speed signals.Afterward,the error energy algorithm precision is utilized to extract abnormal features,leveraging the practical intrinsic mode functions,eliminating extraneous noise and enhancing the signal’s fidelity.This refined signal then becomes the basis for fault analysis.In the analytical step,the cepstrum is employed to calculate the formant and envelope of the reconstructed signal.By scrutinizing the formant and envelope,the fault point within the electromechanical brake system is precisely identified,contributing to a sophisticated and accurate fault diagnosis.Findings–This paper innovatively uses the VMD algorithm for the modal decomposition of electromechanical brake(EMB)motor speed signals and combines it with the error energy algorithm to achieve abnormal feature extraction.The signal is reconstructed according to the effective intrinsic mode functions(IMFS)component of removing noise,and the formant and envelope are calculated by cepstrum to locate the fault point.Experiments show that the empirical mode decomposition(EMD)algorithm can effectively decompose the original speed signal.After feature extraction,signal enhancement and fault identification,the motor mechanical fault point can be accurately located.This fault diagnosis method is an effective fault diagnosis algorithm suitable for EMB systems.Originality/value–By using this improved VMD algorithm,the electromechanical brake system can precisely identify the rotational anomaly of the motor.This method can offer an online diagnosis analysis function during operation and contribute to an automated factory inspection strategy while parts are assembled.Compared with the conventional motor diagnosis method,this improved VMD algorithm can eliminate the need for additional acceleration sensors and save hardware costs.Moreover,the accumulation of online detection functions helps improve the reliability of train electromechanical braking systems.
基金Fellowship of China National Postdoctoral Program for Innovative Talents(Grant No.BX20200268)Research Project of State Key Laboratory of Mechanical System and Vibration(Grant No.MSV202103)+1 种基金National Natural Science Foundation of China(Grant No.51720105016)Higher Education Discipline Innovation Project(Grant No.B12016).
文摘Precision grinding is a key process for realizing the use of large-aperture aspherical optical elements in laser nuclear fusion devices,large-aperture astronomical telescopes,and high-resolution space cameras.In this study,the arc envelope grinding process of large-aperture aspherical optics is investigated using a CM1500 precision grinding machine with a maximum machinable diameter ofΦ1500 mm.The form error of the aspherical workpiece induced by wheel setting errors is analytically modeled for both parallel and cross grinding.Results show that the form error is more sensitive to the wheel setting error along the feed direction than that along the lateral direction.It is a bilinear function of the feed-direction wheel setting error and the distance to the optical axis.Based on the error function above,a method to determine the wheel setting error is proposed.Subsequently,grinding tests are performed with the wheels aligned accurately.Using a newly proposed partial error compensation method with an appropriate compensation factor,a form error of 3.4μm peak-to-valley(PV)for aΦ400 mm elliptical K9 glass surface is achieved.
基金Financial support was provided by a research grant from the University of Macao(Research Grant RG085/09-10S/ZY/ICMS and UL016/09-Y4/CMS/WYT01/ICMS).
文摘In this study,a hydrophobic material,ethylcellulose,which was used as its aqueous suspension Surelease^(®),was combined with a swelling agent as the swelling layer to prepare delayed-release pellets for Danshensu,which is a hydrophilic drug with low MW.A rupturable,delayed-release pellet consists of a drug core,a swelling layer containing a swelling agent(cross-linked sodium carboxymethyl cellulose)with a hydrophobic agent(Surelease^(®)),and a controlled layer composed by an insoluble,water-permeable polymeric coating(aqueous ethylcellulose dispersions)was developed in a fluidised bed.Results showed that blending Surelease^(®)into the swelling layer could effectively extend the release of Danshensu from the pellets,which may be attributed to the slowed swelling rate by reduction of water penetration and improvement of mechanical integrity of the swelling layer.Drug in the delayed pellets showed sustained release in beagle dogs after oral administration with comparable in-vivo exposure to the uncoated drug pellets.In conclusion,blends of hydrophobic and swelling agents in the swelling layer in doublemembrane pellets could achieve a delayed drug-release profile in vitro,as well as delayed and sustained absorption in vivo for highly soluble,low-MW drug.The present study highlighted the potential use of a delayed-release system for other hydrophilic,low-MW drugs to meet the formulation requirements for chronopharmacological diseases.
文摘The removal of metallic impurities from off-grade copper concentrate was investigated in alkaline solution with H2O2. The analysis results of XRD and SEM-EDS revealed the oxidative mechanisms of all sulfides. The influence of various parameters of alkaline leaching were investigated including concentrations of sodium hydroxide and hydrogen peroxide, liquid to solid ratio, leaching time and temperature. The results showed that the removal rate of Mo, As and Zn were increased with increasing leaching time and H2O2 concentration, and that the removal rate of Mo, As and Zn were firstly increased and then slightly decreased with increasing liquid to solid ratio, temperature and NaOH concentration, respectively. More than 95% Mo, 94% As, and 94 % Zn are removed from the off-grade concentrate under the optimum conditions, while only 1.7% Cu is dissolved. These optimum conditions were sodium hydroxide 1.5 mol/L, hydrogen peroxide 1.0 mol/L, temperature 50°C, liquid to solid ratio 5/1 mL/g and leaching time 5 h.
文摘Objective:To study the effect of Danhong injection on neuroendocrine molecules and ventricular remodeling in patients with ischemic cardiomyopathy heart failure.Methods: 80 cases of patients with ischemic cardiomyopathy heart failure who were treated in our hospital between March 2014 and December 2016 were collected and divided into control group (n=40) and observation group (n=40) according to random number table. The control group received regular treatment, the observation group received regular + Danhong injection treatment, and both therapies lasted for 14 d a course, two sessions. Serum contents of neuroendocrine molecules and ventricular remodeling-related indexes, Doppler ultrasonic ventricular remodeling parameter levels, and so on were compared between two groups of patients before and after treatment.Results: Before treatment, serum contents of neuroendocrine molecules and ventricular remodeling-related indexes as well as Doppler ultrasonic ventricular remodeling parameter levels were not statistically different between two groups of patients. After treatment, serum neuroendocrine molecules NT-proBNP, ANP, AngⅡ, ALD and NE contents of observation group were lower than those of control group, serum ventricular remodeling indexes TGF-β1, NF-κB, CysC and FGF23 contents were lower than those of control group, and ultrasonic ventricular remodeling parameters LVMI, LVRI, RVEDV and RVESV levels were lower than those of control group.Conclusion: Adjuvant Danhong injection therapy helps optimize the neuroendocrine molecule contents and inhibit the ventricular remodeling process in patients with ischemic cardiomyopathy heart failure.
基金supported by the Key Science and Technology Project of Hunan Province:Key Technology Collaborative Innovation Project of Improving Emergency and Critical Care Ability and Public Health Emergency Treatment in Hunan Province (2020SK1010)。
文摘Expert consensus proposes an emergency treatment protocol for portal hypertension bleeding. Herein, the emergency treatment procedures, which include first aid, medical, interventional, and surgical treatments, are described. In addition, the indications, contraindications, operating norms, precautions, and prevention of complications of portal hypertension are described to optimize the first aid process.
基金Supported by the National Natural Science Foundation of China(Nos.42076114,41876146)the China Postdoctoral Science Foundation Grant(No.2018M632580)the Special Investigation Project of Scientific and Technological Fundamental Resources(No.2018FY100202)。
文摘The response of phytoplankton and its satellite bacteria to various concentrations(0.01%-10%v/v)of ethanol is studied.To elucidate the effect of ethanol,single-strains of phytoplankton(SSP)culture,pure strains of satellite bacteria isolated from nonaxenic SSP cultures,and Escherichia coli were screened.Results indicate that ethanol could promote the growth and photo synthetic efficiency(F_(v)/F_(m))of S SP at 0.01%and the growth of satellite bacteria at 0.01%-1%.Nevertheless,ethanol inhibited the growth and F_(v)/F_(m)of SSP at 0.1%-1%,and killed bacteria and SSP at 10% concentration.Further investigation on a satellite bacterium(Mameliella alba)revealed that ethanol promotes growth by serving as a growth stimulant rather than a metabolic carbon source.The 16 S rRNA gene amplicon indicated that all nonaxenic S SP cultures harbor distinct satellite bacteria communities where the SSP culture of Skeletonema costatum,Phaeodactylum tricornutum,and Dunaliella bardawil were dominated by bacteria genera of Marivita(~80%),Dinoroseobacter(~47%),and Halomonas(~87%),respectively,indicating that every SSP cultures have their own distinct satellite bacterial community.The bacteria family Rhodobacteraceae was dominant in the two marine diatoms,whereas Halomonadaceae was dominant in the saline green microalga.Compared to their respective controls,the supply of 0.5% ethanol to SSP cultures promoted the growth of the satellite bacteria but did not cause a significant difference in species composition of satellite bacteria.Therefore,a low concentration of ethanol can promote the growth of bacteria in a non-selective way.This study enriched our knowledge about the effect of ethanol on aquatic microbes and provided a baseline for basic and applied biotechnological re search in the aquatic environment in the future.
基金supported by National Natural Science Foundation(No.41272301 and No.42007171)Nature Fund of Hebei(No.D2021504034)Chinese Academy of Geological Sciences(No.YYWF201628).
文摘The increasing severity of ground subsidence,ground fissure and other disasters caused by the excessive exploitation of deep underground resources has highlighted the pressing need for effective management.A significant contributing factor to the challenges faced is the inadequacy of existing soil mechanics experimental instruments in providing effective indicators,creating a bottleneck in comprehensively understanding the mechanisms of land subsidence.It is urgent to develop a multi-field and multi-functional soil mechanics experimental system to address this issue.Based soil mechanics theories,the existing manufacturing capabilities of triaxial apparatus and the practical demands of the test system,a set of multi-field coupled high-pressure triaxial system is developed tailored for testing deep soils(at depths of approximately 3000 m)and soft rock.This system incorporates specialized design elements such as high-pressure chamber and horizontal deformation testing devices.In addition to the conventional triaxial tester functions,its distinctive feature encompass a horizontal deformation tracking measuring device,a water release testing device and temperature control device for the sample.This ensemble facilitates testing of horizontal and vertical deformation water release and other parameters of samples under a specified stress conditions,at constant or varying temperature ranging from-40℃–90℃.The accuracy of the tested parameters meets the requirements of relevant current specifications.The test system not only provides scientifically robust data for revealing the deformation and failure mechanism of soil subjected to extreme temperature,but also offers critical data support for major engineering projects,deep exploration and mitigation efforts related to soil deformation-induced disaster.
文摘<strong>Objective: </strong>This study aimed to clarify the death characteristics of esophageal cancer in Inner Mongolia and the population distribution with various education levels. <strong>Methods:</strong> The mortality rate of esophageal cancer was calculated using the monitoring point of Death Registry System in Inner Mongolia from 2009 to 2015. The gender, age, region, ethnicity at two education levels of percentage were calculated and the <em>χ</em><sup>2</sup> test was executed. <strong>Result:</strong> The mortality rate of esophageal cancer was 10.10/105, China Adjustment Mortality was 10.97/10<sup>5</sup>, World Adjustment Mortality was 9.08/10<sup>5</sup> in Inner Mongolia. The death of esophageal cancer showed statistical significance at two educational levels (P < 0.05). High school and below accounted for 93.9% at the education level, and above high school accounted for 3.5%. In addition, there were significant differences in the percentage of death by gender, age and region at two educational levels (P < 0.05). <strong>Conclusion:</strong> Education level has a certain relation with the death of esophageal cancer. To improve the health level, health education plans can be formulated according to esophageal cancer prevention relevant policy with different education levels.
