Regulated cell death is a genetically determined form of programmed cell death that commonly occurs during the development of living organisms.This process plays a crucial role in modulating homeostasis and is evoluti...Regulated cell death is a genetically determined form of programmed cell death that commonly occurs during the development of living organisms.This process plays a crucial role in modulating homeostasis and is evolutionarily conserved across a diverse range of living organisms.Ferroptosis is a classic regulatory mode of cell death.Extensive studies of regulatory cell death in Alzheimer’s disease have yielded increasing evidence that fe rroptosis is closely related to the occurrence,development,and prognosis of Alzheimer’s disease.This review summarizes the molecular mechanisms of ferroptosis and recent research advances in the role of ferro ptosis in Alzheimer’s disease.Our findings are expected to serve as a theoretical and experimental foundation for clinical research and targeted therapy for Alzheimer’s disease.展开更多
Crop type mapping using remote sensing is critical for global agricultural monitoring and food security.However,the complexity of crop planting patternsand spatial heterogeneity pose significant challenges to field da...Crop type mapping using remote sensing is critical for global agricultural monitoring and food security.However,the complexity of crop planting patternsand spatial heterogeneity pose significant challenges to field data collection,thereby limiting the accuracy of remotely sensed crop mapping.This study proposed a new approach for rapidly collecting field crop data by integrating unmanned aerial vehicle(UAV)images with the YOLOv3(You Only Look Once version 3)algorithm.The impacts of UAV flight altitude and the number of training samples on the accuracy of crop identification models were investigated using peanut,soybean,and maize as examples.The results showed that the average Fl-score for crop type detection accuracy reached 0.91 when utilizing UAV images captured at an altitude of 20 m.In addition,a positive correlation was observed between identification accuracy and the number of training samples.The model developed in this study can rapidly and automatically identify crop types from UAV images,which significantly improves the survey efficiency and provides an innovative solution for acquiring field crop data in large areas.展开更多
An improved self-mixing grating interferometer based on the Littrow structure has been proposed in this Letter to measure displacement.The grating is integrated inside the interferometer to reduce the impact on the vi...An improved self-mixing grating interferometer based on the Littrow structure has been proposed in this Letter to measure displacement.The grating is integrated inside the interferometer to reduce the impact on the vibration parameters of the object caused by the grating attached to the vibrating object.The+1 st diffracted light returns to the laser cavity after being reflected by the target object,and self-mixing interference occurs.The displacement can be reconstructed by processing the self-mixing signals.The feasibility of the proposed interferometer is demonstrated by experimental measurements,and results show that it can achieve micro displacement measurement with the maximum absolute errors of less than 50 nm.展开更多
基金supported by the National Natural Science Foundation of China,No.81501106(to CF)Fund of Taishan Scholar Project(to CF)+1 种基金the Natural Science Foundation of Shandong Province,No.ZR2020QH106(to YH)the Medical and Health Science and Technology Development Plan of Shandong Province,No.202203010799(to QS)。
文摘Regulated cell death is a genetically determined form of programmed cell death that commonly occurs during the development of living organisms.This process plays a crucial role in modulating homeostasis and is evolutionarily conserved across a diverse range of living organisms.Ferroptosis is a classic regulatory mode of cell death.Extensive studies of regulatory cell death in Alzheimer’s disease have yielded increasing evidence that fe rroptosis is closely related to the occurrence,development,and prognosis of Alzheimer’s disease.This review summarizes the molecular mechanisms of ferroptosis and recent research advances in the role of ferro ptosis in Alzheimer’s disease.Our findings are expected to serve as a theoretical and experimental foundation for clinical research and targeted therapy for Alzheimer’s disease.
基金supported by the National Natural Science Foundation of China(Grant Nos.41801023 and 42071056).
文摘Crop type mapping using remote sensing is critical for global agricultural monitoring and food security.However,the complexity of crop planting patternsand spatial heterogeneity pose significant challenges to field data collection,thereby limiting the accuracy of remotely sensed crop mapping.This study proposed a new approach for rapidly collecting field crop data by integrating unmanned aerial vehicle(UAV)images with the YOLOv3(You Only Look Once version 3)algorithm.The impacts of UAV flight altitude and the number of training samples on the accuracy of crop identification models were investigated using peanut,soybean,and maize as examples.The results showed that the average Fl-score for crop type detection accuracy reached 0.91 when utilizing UAV images captured at an altitude of 20 m.In addition,a positive correlation was observed between identification accuracy and the number of training samples.The model developed in this study can rapidly and automatically identify crop types from UAV images,which significantly improves the survey efficiency and provides an innovative solution for acquiring field crop data in large areas.
基金supported by the Northeast Petroleum University Youth Science Foundation(No.2020QNL-13)。
文摘An improved self-mixing grating interferometer based on the Littrow structure has been proposed in this Letter to measure displacement.The grating is integrated inside the interferometer to reduce the impact on the vibration parameters of the object caused by the grating attached to the vibrating object.The+1 st diffracted light returns to the laser cavity after being reflected by the target object,and self-mixing interference occurs.The displacement can be reconstructed by processing the self-mixing signals.The feasibility of the proposed interferometer is demonstrated by experimental measurements,and results show that it can achieve micro displacement measurement with the maximum absolute errors of less than 50 nm.
