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Role of the hippocampus in contextual modulation of fear extinction
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作者 lingzhi kong Xihong Wu Liang Li 《Neural Regeneration Research》 SCIE CAS CSCD 2008年第12期1386-1389,共4页
Fear extinction is an important form of emotional learning, and affects neural plasticity. Cue fear extinction is a classical form of inhibitory learning that can be used as an exposure-based treatment for phobia, bec... Fear extinction is an important form of emotional learning, and affects neural plasticity. Cue fear extinction is a classical form of inhibitory learning that can be used as an exposure-based treatment for phobia, because the long-term extinction memory produced during cue fear extinction can limit the over-expression of fear. The expression of this inhibitory memory partly depends on the context in which the extinction learning occurs. Studies such as transient inhibition, electrophysiology and brain imaging have proved that the hippocampus - an important structure in the limbic system - facilitates memory retrieval by contextual cues. Mediation of the hippocampus-medial prefrontal lobe circuit may be the neurobiological basis of this process. This article has reviewed the role of the hippocampus in the learning and retrieval of fear extinction. Contextual modulation of fear extinction may rely on a neural network consisting of the hippocampus, the medial prefrontal cortex and the amygdala. 展开更多
关键词 HIPPOCAMPUS FEAR EXTINCTION context-specific exposure-based treatment
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Improvement of a continuous-variable measurement-device-independent quantum key distribution system via quantum scissors
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作者 lingzhi kong Weiqi Liu +3 位作者 Fan Jing Zhe-Kun Zhang Jin Qi Chen He 《Chinese Physics B》 SCIE EI CAS CSCD 2022年第9期202-207,共6页
We propose a new scheme to enhance the performance of the Gussian-modulated coherent-state continuous-variable measurement-device-independent quantum key distribution(CV-MDI-QKD)system via quantum scissors(QS)operatio... We propose a new scheme to enhance the performance of the Gussian-modulated coherent-state continuous-variable measurement-device-independent quantum key distribution(CV-MDI-QKD)system via quantum scissors(QS)operation at Bob's side.As an non-deterministic amplifying setup,we firstly introduce the QS-enhanced CV-MDI-QKD protocol and then investigate the success probability of the QS operation in accordance with the equivalent one-way scheme.Afterwards,we investigate the effect of the QS operation on the proposed scheme and analyze the performance of the QS-enhanced CV-MDI-QKD system under the extreme asymmetric circumstance.Simulation results show that the QS operation can indeed improve the performance of the CV-MDI-QKD system considerably.QS-enhanced CV-MDI-QKD protocol outperforms the original CV-MDI-QKD protocol in both the maximum transmission distance and the secret key rate.Moreover,the better the performance of QS operation,the more significant the improvement of performance of the system. 展开更多
关键词 measurement-device-independent quantum key distribution quantum scissors performance
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Practical security analysis of continuous-variable quantum key distribution with an unbalanced heterodyne detector
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作者 lingzhi kong Weiqi Liu +1 位作者 Fan Jing Chen He 《Chinese Physics B》 SCIE EI CAS CSCD 2022年第7期119-126,共8页
When developing a practical continuous-variable quantum key distribution(CVQKD),the detector is necessary at the receiver's side.We investigate the practical security of the CVQKD system with an unbalanced heterod... When developing a practical continuous-variable quantum key distribution(CVQKD),the detector is necessary at the receiver's side.We investigate the practical security of the CVQKD system with an unbalanced heterodyne detector.The results show that unbalanced heterodyne detector introduces extra excess noise into the system and decreases the lower bound of the secret key rate without awareness of the legitimate communicators,which leaves loopholes for Eve to attack the system.In addition,we find that the secret key rate decreases more severely with the increase in the degree of imbalance and the excess noise induced by the imbalance is proportional to the intensity of the local oscillator(LO)under the same degree of imbalance.Finally,a countermeasure is proposed to resist these kinds of effects. 展开更多
关键词 continuous-variable quantum key distribution heterodyne detector
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中国西部贫困农村孕期微营养素补充对出生体重、分娩孕周和围产儿死亡影响的研究:双盲整群随机对照试验
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作者 Lingxia Zeng Michael J Dibley +5 位作者 Yue Cheng Shaonong Dang Suying Chang lingzhi kong Hong Yan 曾令霞(译) 《英国医学杂志中文版》 2009年第1期23-27,共5页
目的以单纯补充叶酸为对照,评价孕期补充多种微营养素或铁/叶酸对出生体重、分娩孕周和孕晚期血红蛋白的影响。设计采用整群随机双盲对照试验设计。地点中国陕西省的两个贫困县(长武县和彬县)。研究对象5828名孕妇及其分娩的4697名... 目的以单纯补充叶酸为对照,评价孕期补充多种微营养素或铁/叶酸对出生体重、分娩孕周和孕晚期血红蛋白的影响。设计采用整群随机双盲对照试验设计。地点中国陕西省的两个贫困县(长武县和彬县)。研究对象5828名孕妇及其分娩的4697名活产新生儿。干预措施以村为单位整群随机化,同一个村的孕妇孕期每天补充叶酸(对照组)、铁/叶酸或多微营养素。多微营养素含15种推荐量的维生素和矿物质。主要结局指标测量出生体重、身长、头围在产后72小时内测量。通过产后42天访视收集新生儿生存情况。结果与单纯补充叶酸比较,多微营养素可显著提高出生体重42g(95%CI7—78g);孕期补充多微营养素和铁/叶酸均可显著增加分娩孕周(铁/叶酸:0.23周,95%CI0.10~0.36周;多微营养素:0.19周,95%CI0.06~0.32周)。铁/叶酸可显著减少34周以内的早产(RR0.50,95%CI0.27~0.94,P=0.031)。相对于纯叶酸组,多微营养素和铁/叶酸均可显著增加孕妇孕晚期的血红蛋白水平(铁/叶酸:5.0g/L,95%CI2.0~8.0g/L,P=0.001;多微营养素:6.9g/L,95%CI4.1~9.6g/L,P〈0.001)。孕期营养素补充对围产儿死亡没有明显影响,但铁/叶酸可减少54%(RR0.46,95%CI0.21~0.98)的7天内新生儿死亡。结论与对照组(叶酸)比较,在中国贫困农村孕期补充铁/叶酸可延长分娩孕周从而减少早期新生儿死亡;多微营养素可适当增加出生体重,尽管如此,对早期新生儿死亡并无明显影响。在孕期微营养素干预中,剂量充足的铁对于降低发展中国家的新生儿死亡是最关键的。 展开更多
关键词 随机双盲对照 出生体重 分娩孕周 营养素补充 围产儿死亡 中国西部 贫困农村 随机对照试验
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