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Searching for ^(76)Ge neutrinoless double beta decay with the CDEX-1B experiment
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作者 Bing-Tao Zhang Jun-Zheng Wang +82 位作者 Li-Tao Yang Qian Yue Ke-Jun Kang Yuan-Jing Li Hai-Peng An C.Greeshma Jian-Ping Chang Yun-Huan Chen Jian-Ping Cheng Wen-Han Dai Zhi Deng Chang-Hao Fang Xin-Ping Geng Hui Gong Qiu-Ju Guo Xu-Yuan Guo Li He Sheng-Ming He Jin-Wei Hu Han-Xiong Huang Tu-Chen Huang Hai-Tao Jia Xi Jiang S.Karmakar Hao-Bin Li Jian-Min Li Jin Li Qian-Yun Li Ren-Ming-Jie Li Xue-Qian Li Yu-Lan Li Yi-Fan Liang Bin Liao Fong-Kay Lin Shin-Ted Lin Jia-Xuan Liu Shu-Kui Liu Yan-Dong Liu Yu Liu Yuan-Yuan Liu Zhong-Zhi Liu Hao Ma Yu-Cai Mao Qi-Yuan Nie Jin-Hua Ning Hui Pan Ning-Chun Qi Jie Ren Xi-Chao Ruan Ze She manoj kumar singh Tian-Xi Sun Chang-Jian Tang Wei-You Tang Yang Tian Guang-Fu Wang Li Wang Qing Wang Yu-Feng Wang Yun-Xiang Wang Henry-Tsz-King Wong Shi-Yong Wu Yu-Cheng Wu Hao-Yang Xing Rui Xu Yin Xu Tao Xue Yu-Lu Yan Nan Yi Chun-Xu Yu Hai-Jun Yu Jian-Feng Yue Ming Zeng Zhi Zeng Feng-Shou Zhang Lei Zhang Zhen-Hua Zhang Zhen-Yu Zhang Kang-Kang Zhao Ming-Gang Zhao Ji-Fang Zhou Zu-Ying Zhou Jing-Jun Zhou 《Chinese Physics C》 SCIE CAS CSCD 2024年第10期11-22,共12页
We operated a p-type point contact high purity germanium(PPCGe)detector(CDEX-1B,1.008 kg)in the China Jinping Underground Laboratory(CJPL)for 500.3 days to search for neutrinoless double beta(0νββ)decay of ^(76)Ge.... We operated a p-type point contact high purity germanium(PPCGe)detector(CDEX-1B,1.008 kg)in the China Jinping Underground Laboratory(CJPL)for 500.3 days to search for neutrinoless double beta(0νββ)decay of ^(76)Ge.A total of 504.3 kg⋅day effective exposure data was accumulated.The anti-coincidence and the multi/single-site event(MSE/SSE)discrimination methods were used to suppress the background in the energy region of interest(ROI,1989–2089 keV for this work)with a factor of 23.A background level of 0.33 counts/(keV⋅kg⋅yr)was realized.The lower limit on the half life of^(76)Ge 0νββdecay was constrained as T_(1/2)^(0ν)>1.0×10^(23)yr(90%C.L.),corresponding to the upper limits on the effective Majorana neutrino mass:<mββ><3.2–7.5 eV. 展开更多
关键词 neutrinoless double beta decay CDEX point-contact germanium detector ^(76)Ge
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Transition from open to robotic assisted liver resection:A retrospective comparative study.Is experience of laparoscopic liver resections needed? 被引量:2
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作者 Sanjay Goja Sanjay kumar Yadav +2 位作者 Rohan Jagat Chaudhary manoj kumar singh Arvinder singh Soin 《Laparoscopic, Endoscopic and Robotic Surgery》 2019年第4期94-98,共5页
Objective:The authors present outcomes of robotic liver resections in comparison with open technique questioning the need to have experience of laparoscopy for such procedures before transition to robotic assisted.Mat... Objective:The authors present outcomes of robotic liver resections in comparison with open technique questioning the need to have experience of laparoscopy for such procedures before transition to robotic assisted.Materials and methods:Retrospective review of liver resections done robotically from February 2015 to June 2017 compared to matched control cohort of open cases from January 2012 to December 2016.Results:Twenty-one patients in the study groupwere comparedwithmatched control of 42 open cases(1:2 ratio).The types of procedure were similar in both the groups.There were 4 left lateral hepatectomy,3 left hepatectomy,and 1 left hepatectomy with hepatico-jejunostomy,3 right hepatectomy,3 right posterior sectorectomy,4 bisegmentectomy and 4 mono-segmentectomy.There were 9 patients with primary liver cancer,2 each with livermetastasis and carcinoma gall bladder and 8 patients had benign liver disease.Mean blood losswas 370±311ml in the robotic group compared to 451±330ml in control group(p=0.06).Minor complications developed in 19.0%of robotic cases compared to 40.5%in open surgery,while major complications occurred in 4.7%of robotic cases compared to 7.1%of open cases.Mean hospital staywas 5.3±0.8 days for the robotic group and 7.7±4.2 days for open group(p=0.02).Local tumor recurrence occurred in 1 out of 13 resections done for malignancy in the robotic group and 7 out of 26 in the open group.Conclusion:This study highlights the utility of surgical robots for segmental and complex liver resections with equivalent outcomes and decreased length of hospital stay compared to open surgery without having experience of same with the laparoscopy. 展开更多
关键词 ROBOTIC Liver resection Open surgery
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The bacteriophage mu lysis system–A new mechanism of host lysis?
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作者 SAIKAT SAMANTA ASHISH RANJAN SHARMA +6 位作者 ABINIT SAHA manoj kumar singh ARPITA DAS manojIT BHATTACHARYA RUDRA PRASAD SAHA SANG-SOO LEE CHIRANJIB CHAKRABORTY 《BIOCELL》 SCIE 2021年第5期1175-1186,共12页
Bacteriophages are viruses that infect bacteria and can choose any one of the two alternative pathways for infection,i.e.,lysis or lysogeny.Phage lysis is one of the conventional biological processes required to sprea... Bacteriophages are viruses that infect bacteria and can choose any one of the two alternative pathways for infection,i.e.,lysis or lysogeny.Phage lysis is one of the conventional biological processes required to spread infection from one bacterium to another.Our analysis suggests that in the paradigm bacteriophage Mu,six proteins might be involved in host cell lysis.Mu has a broad host range,and Mu-like phages were found in both Gram-negative and Gram-positive bacteria.An analysis of the genomes of Mu and Mu-like phages could be useful in elucidating the lysis mechanism in this group of phages.A detailed review of the various mechanisms of phage lysis and different proteins associated with the process will help researchers understand the phage biology and their life cycle in different bacteria.The recent increase in the number of multidrug-resistant(MDR)strains of bacteria and the usual long-term nature of new drug development has encouraged scientists to look for alternative strategies like phage therapy and the discovery of new lysis mechanisms.Understanding the lysis mechanism in the Mu-like phages could be exploited to develop alternative therapeutics to kill drug-resistant pathogenic bacteria.In this review article,we have analyzed the phage Mu-mediated host lysis system,which is unknown till now,and our analysis indicates a possibility of the existence of a new lysis mechanism operating in Mu. 展开更多
关键词 Bacteriophage Mu Host cell lysis ENDOLYSIN HOLIN Spanin
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Supplementation of L-ascorbic acid improves the in vitro development of buffalo(Bubalus bubalis)embryos and alters the expression of apoptosis-related genes
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作者 Mayank Roshan Diksha Dua +6 位作者 Ankur Sharma Manish Tiwari manoj kumar singh Suresh kumar Singla Prabhat Palta Radhay Sham Manik Manmohan singh Chauhan 《Asian pacific Journal of Reproduction》 2021年第1期36-42,共7页
Objective:To study the effect of L-ascorbic acid supplementation on the in vitro development of buffalo embryos and evaluate the relative mRNA abundance of some pro-apoptotic,anti-apoptotic,and embryonic development-r... Objective:To study the effect of L-ascorbic acid supplementation on the in vitro development of buffalo embryos and evaluate the relative mRNA abundance of some pro-apoptotic,anti-apoptotic,and embryonic development-related genes.Methods:In experiment 1,we evaluated the effect of the addition of 0(control),50,and 100μM L-ascorbic acid to the in vitro maturation medium on the developmental competence in terms of blastocyst rate and relative mRNA abundance of some pro-apoptotic(BAX,BID),anti-apoptotic(BCL-XL,MCL1),and embryonic development(GDF9,BMP15)related genes.Based on the results,we chose 50μM as the suitable dose of L-ascorbic acid for the subsequent experiments.We further evaluated the blastocyst rates following the addition of 50μM L-ascorbic acid to the in vitro culture medium(experiment 2),and in vitro maturation and in vitro culture media(experiment 3).In all three experiments,the maturation and culture media devoid of L-ascorbic acid served as the control group.Results:The blastocyst rate after adding 50μM L-ascorbic acid to the in vitro maturation medium was significantly higher than the control group(P<0.05),whereas 100μM L-ascorbic acid exhibited a negative effect on the blastocyst rate.The blastocyst rates for embryos cultured in 50μM L-ascorbic acid in the in vitro culture medium alone and both in vitro maturation and in vitro culture media were significantly higher than their corresponding control groups(P<0.05).The relative mRNA abundance of BAX significantly decreased in blastocysts produced after the addition of 50μM L-ascorbic acid as compared with the control group(P<0.05),whereas,for MCL1,it significantly decreased in blastocysts produced after the addition of 100μM L-ascorbic acid(P<0.05).Conclusions:The supplementation of 50μM L-ascorbic acid to in vitro maturation and in vitro culture media supports in vitro embryonic development in buffaloes by improving developmental competence and altering the expression of apoptosis-related genes. 展开更多
关键词 BUFFALO BLASTOCYST In vitro embryo production L-ascorbic acid OOCYTE
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Leaf Colour Chart vis-a-vis Nitrogen Management in Different Rice Genotypes
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作者 Avijit Sen Vinod kumar Srivastava +2 位作者 manoj kumar singh Ram kumar singh Suneel kumar 《American Journal of Plant Sciences》 2011年第2期223-236,共14页
A field trial comprising 3 rice varieties (NDR-359, Sarju 52, HUBR 2-1) and 4 LCC scores (≤ 2, ≤ 3, ≤ 4, ≤ 5) along with the recommended dose of N was conducted in a split plot design to calibrate the LCC for nitr... A field trial comprising 3 rice varieties (NDR-359, Sarju 52, HUBR 2-1) and 4 LCC scores (≤ 2, ≤ 3, ≤ 4, ≤ 5) along with the recommended dose of N was conducted in a split plot design to calibrate the LCC for nitrogen requirement of rice. Maximum grain yields of NDR-359, Sarju 52 at LCC ≤ 5 and HUBR 2-1 at LCC ≤ 4 were found to be 47.10, 40.66 and 36.04 q/ha respectively. The critical LCC score for real time nitrogen requirement for NDR 359 and Sarju 52 was found to be ≤ 5, while for HUBR 2-1 it was ≤ 4. Agronomic and recovery efficiency of nitrogen also followed the same trend. In the functional relationship between SPAD value and LCC score, while it was linear in NDR-359 and Sarju 52, for HUBR 2-1 it was quadratic. Further a positive correlation between SPAD values and LCC score was observed in all the 3 varieties. 展开更多
关键词 LEAF COLOUR CHART (LCC) Nitrogen Rice
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Handwritten Character Recognition Using Multiresolution Technique and Euclidean Distance Metric
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作者 Dileep kumar Patel Tanmoy Som +1 位作者 Sushil kumar Yadav manoj kumar singh 《Journal of Signal and Information Processing》 2012年第2期208-214,共7页
In the present paper, the problem of handwritten character recognition has been tackled with multiresolution technique using discrete wavelet transform (DWT) and Euclidean distance metric (EDM). The technique has been... In the present paper, the problem of handwritten character recognition has been tackled with multiresolution technique using discrete wavelet transform (DWT) and Euclidean distance metric (EDM). The technique has been tested and found to be more accurate and faster. Characters is classified into 26 pattern classes based on appropriate properties. Features of the handwritten character images are extracted by DWT used with appropriate level of multiresolution technique, and then each pattern class is characterized by a mean vector. Distances from input pattern vector to all the mean vectors are computed by EDM. Minimum distance determines the class membership of input pattern vector. The proposed method provides good recognition accuracy of 90% for handwritten characters even with fewer samples. 展开更多
关键词 Discrete WAVELET TRANSFORM Euclidean Distance METRIC Feature Extraction Handwritten CHARACTER Recognition Bounding BOX Mean Vector
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First results on ^(76)Ge neutrinoless double beta decay from CDEX-1 experiment 被引量:7
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作者 Li Wang Qian Yue +66 位作者 KeJun Kang JianPing Cheng YuanJing Li TszKing Henry Wong ShinTed Lin JianPing Chang JingHan Chen QingHao Chen YunHua Chen Zhi Deng Qiang Du Hui Gong Li He QingJu He JinWei Hu HanXiong Huang TengRui Huang LiPing Jia Hao Jiang HauBin Li Hong Li JianMin Li Jin Li Jun Li Xia Li XueQian Li YuLan Li FongKay Lin ShuKui Liu Hao Ma JingLu Ma XingYu Pan Jie Ren XiChao Ruan ManBin Shen Vivek Sharma Lakhwinder singh manoj kumar singh manoj kumar singh Arun kumar Soma ChangJian Tang WeiYou Tang ChaoHsiung Tseng JiMin Wang Qing Wang ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue LiTao Yang SongWei Yang Nan Yi ChunXu Yu HaiJun Yu WeiHe Zeng XiongHui Zeng Zhi Zeng Lan Zhang YunHua Zhang MingGang Zhao Wei Zhao JiFang Zhou ZuYing Zhou JingJun Zhu WeiBin Zhu ZhongHua Zhu 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS CSCD 2017年第7期53-59,共7页
We report the first results on 76Ge neutrinoless double beta decay from stage one of the China dark-matter experiment (CDEX). A p-type point-contact high-purity germanium detector with a mass of 994g has been instal... We report the first results on 76Ge neutrinoless double beta decay from stage one of the China dark-matter experiment (CDEX). A p-type point-contact high-purity germanium detector with a mass of 994g has been installed to detect neutrinoless double beta decay events, as well as to directly detect dark matter particles. An exposure of 304kgd has been analyzed over a wide spectral band from 500keV to 3MeV. The average event rate obtained was about 0.012 counts per keV per kg per day over the 2.039MeV energy range. The half-life of76Ge neutrinoless double beta decay derived based on this result is 70v2〉6.4× 1022 yr (90%C.L.). An upper limit on the effective Majorana-neutrino mass of 5.0eV has been achieved. 展开更多
关键词 neutrinoless double beta decay CDEX point-contact germanium detector 76Ge isotope
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CDEX-1 1 kg point-contact germanium detector for low mass dark matter searches 被引量:3
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作者 康克军 岳赛 +73 位作者 吴呈城 程建平 李元景 白杨 毕勇 常建平 陈楠 陈宁 陈庆豪 陈云华 庄又澄 邓智 杜强 宫辉 郝喜庆 何庆驹 胡鑫洄 黄瀚雄 黄腾锐 江灏 李浩斌 李荐民 李金 李军 李霞 李新颖 李学潜 李玉兰 廖恒毅 林枫凯 林欣德 刘书魁 吕岚春 马豪 毛绍基 覃建强 任杰 任婧 阮锡超 申满斌 Lakhwinder singh manoj kumar singh Arun kumar SOMA 苏健 唐昌建 曾昭雄 王继敏 王力 王青 王子敬 吴世勇 吴蔚 吴玉成 幸浩洋 徐音 薛涛 杨丽桃 杨松纬 易难 喻纯旭 于昊 余训臻 曾雄辉 曾志 张岚 张蕴华 赵明刚 赵伟 钟苏宁 周祖英 朱敬军 朱维彬 朱学洲 朱忠华 《Chinese Physics C》 SCIE CAS CSCD 2013年第12期58-64,共7页
The CDEX collaboration has been established for direct detection of light dark matter particles, using ultra-low energy threshold point-contact p-type germanium detectors, in China JinPing underground Laboratory (CJP... The CDEX collaboration has been established for direct detection of light dark matter particles, using ultra-low energy threshold point-contact p-type germanium detectors, in China JinPing underground Laboratory (CJPL). The first 1 kg point-contact germanium detector with a sub-keV energy threshold has been tested in a passive shielding system located in CJPL. The outputs from both the point-contact P+ electrode and the outside N+ electrode make it possible to scan the lower energy range of less than 1 keV and at the same time to detect the higher energy range up to 3 MeV. The outputs from both P+ and N+ electrode may also provide a more powerful method for signal discrimination for dark matter experiment. Some key parameters, including energy resolution, dead time, decay times of internal X-rays, and system stability, have been tested and measured. The results show that the 1 kg point-contact germanium detector, together with its shielding system and electronics, can run smoothly with good performances. This detector system will be deployed for dark matter search experiments. 展开更多
关键词 CDEX point-contact germanium detector dark matter CJPL
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Limits on light WIMPs with a 1 kg-scale germanium detector at 160 eVee physics threshold at the China Jinping Underground Laboratory 被引量:1
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作者 杨丽桃 李浩斌 +65 位作者 岳骞 康克军 程建平 李元景 王子敬 M.Agartioglu 安海鹏 常建平 陈景瀚 陈云华 邓智 杜强 宫辉 何力 胡津纬 胡庆东 黄瀚雄 贾历平 江灏 李红 李荐民 李金 李霞 李学潜 李玉兰 林枫凯 林兴德 刘书魁 刘仲智 马豪 马菁露 潘辉 任杰 阮锡超 B.Sevda Vivek Sharma 申满斌 Lakhwinder singh manoj kumar singh 唐昌建 唐维优 田阳 王继敏 王力 王青 王轶 吴世勇 吴玉成 幸浩洋 徐音 薛涛 杨松伟 易难 喻纯旭 于海军 岳剑峰 曾雄辉 曾鸣 曾志 张云华 赵明刚 赵伟 周济芳 周祖英 朱敬军 朱忠华 《Chinese Physics C》 SCIE CAS CSCD 2018年第2期12-21,共10页
We report results of a search for light weakly interacting massive particle(WIMP) dark matter from the CDEX-1 experiment at the China Jinping Underground Laboratory(CJPL). Constraints on WIMP-nucleon spin-independ... We report results of a search for light weakly interacting massive particle(WIMP) dark matter from the CDEX-1 experiment at the China Jinping Underground Laboratory(CJPL). Constraints on WIMP-nucleon spin-independent(SI) and spin-dependent(SD) couplings are derived with a physics threshold of 160 eVee, from an exposure of 737.1 kg-days. The SI and SD limits extend the lower reach of light WIMPs to 2 GeV and improve over our earlier bounds at WIMP mass less than 6 GeV. 展开更多
关键词 dark matter WIMPS CDEX pPCGe
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Product and Commutators of Pseudo-differential Operators Involving Fourier–Jacobi Transform
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作者 Akhilesh Prasad manoj kumar singh 《Communications in Mathematics and Statistics》 SCIE 2022年第1期67-84,共18页
The purpose of this paper is to define a new symbol classand discuss the theory of two different pseudo-differential operators(p.d.o.)involving Fourier–Jacobi transform associated with a single symbol in.We also deri... The purpose of this paper is to define a new symbol classand discuss the theory of two different pseudo-differential operators(p.d.o.)involving Fourier–Jacobi transform associated with a single symbol in.We also derive boundedness results for p.d.o.’s in Sobolev type space.Anewpseudo-differential operator is developed using the product of symbols.Finally,norm inequality for commutators between two pseudo-differential operators is obtained. 展开更多
关键词 Jacobi functions Fourier-Jacobi transform Sobolev space Pseudo-differential operators
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