Large subunit gene of rubisco (rbcL) of cyanobacteria Arthrospira platensis FACHB341, A. Platensis FACHB439, A. Maxima OUQDSM and Spirulina sp. FACHB440 is cloned, sequenced and characterized. Results show that GC con...Large subunit gene of rubisco (rbcL) of cyanobacteria Arthrospira platensis FACHB341, A. Platensis FACHB439, A. Maxima OUQDSM and Spirulina sp. FACHB440 is cloned, sequenced and characterized. Results show that GC content of the gene in strain Spirulina sp. FACHB440 is higher than that in the others. The alignments based on deduced amino acid sequences indicate that Spirulina sp. FACHB440 is different from that in other three samples of Arthrospira, though they have the same conserved functional sites (95, 98, 121, 124, 221, 257). The nucleotide sequence similarity among the three strains of the genus of Arthrospira (96.5～99.6%) is higher than that between Arthrospira and Spirulina (78.1～78.5%). By comparison of the corresponding sequence of other cyanobacteria, a phylogenetic tree with two clusters is constructed. A. Platensis FACHB341, A. Maxima OUQDSM and A. Platensis FACHB439 form the monophyletic linage, which is fully supported by bootstrap values (1000), while Spirulina sp. FACHB440 and Anabaena sp. PCC7120 cluster in another linage with the bootstrap value of 909.展开更多
The cardiovascular system with a lumped parameter model is treated, in which the Starling model is used to simulate left ventricle and the four-element Burattini & Gnudi model is used in the description of arteria...The cardiovascular system with a lumped parameter model is treated, in which the Starling model is used to simulate left ventricle and the four-element Burattini & Gnudi model is used in the description of arterial system. Moreover, the feedback action of arterial pressure on cardiac cycle is taken into account. The phenomenon of mechanical periodicity (MP) of end diastolic volume (EDV) of left ventricle is successfully simulated by solving a series of one-dimensional discrete nonlinear dynamical equations. The effects of cardiovascular parameters on MP is also discussed.展开更多
Summary: Occlusal-maxillo-facial structural change of crossbite malocclusion after orthodontic therapy by modified ACTIVATOR appliance was investigated. Eighty crossbite cases of deciduous dentition and mixed dentitio...Summary: Occlusal-maxillo-facial structural change of crossbite malocclusion after orthodontic therapy by modified ACTIVATOR appliance was investigated. Eighty crossbite cases of deciduous dentition and mixed dentition were treated by modified ACTIVATOR. Through pre- and post-treatment analysis of stone model, Schuller’s position X-ray and craniofaciometrics, the change in craniofacial length, width and height in early-phase crossbite malocclusion was studied. The results showed that there was no significant change in the width of maxillary and mandibular dental arch. Maxillary length and protrusion was increased significantly, upper incisors slopped labially. The lower incisors slopped lingually, mental angle decreased more severely. The lower and posterior facial height was increased to normal level.展开更多
The most popular estimation method for HMMs is Baum Welch algorithm, which is based on the maximum likelihood(ML) criterion. For other criteria, such as Maximum Mutual Information (MMI) criterion, such an algorithm do...The most popular estimation method for HMMs is Baum Welch algorithm, which is based on the maximum likelihood(ML) criterion. For other criteria, such as Maximum Mutual Information (MMI) criterion, such an algorithm does not exist. In this case, a gradient based method is considered. With the complexity of the objective function, the computation of the gradients has to be solved before it can be applied to this problem. This paper proposed an implementation method of the gradient based method. Experimental results indicate that this method produces monotonous improvement like Baum Welch algorithm.展开更多
Objectives: To investigate the effects of insulin resistance on serum androgen level and ovulation of women with polycystic ovary syndrome (PCOS) and observe clinic role of acarbose in the treatment of hyperinsulinemi...Objectives: To investigate the effects of insulin resistance on serum androgen level and ovulation of women with polycystic ovary syndrome (PCOS) and observe clinic role of acarbose in the treatment of hyperinsulinemia, postprandial hyperglycemia and anovulation. Methods: 14 women accompanied by postprandial hyperglycemia with PCOS were administrated by acarbose for 12 weeks.14 age-matched individuals who had similar body mass index and normal menstruation were served as controls. Results: Serum T levels declined significantly from 4.09±1.04 nmol/L to 1.71±0.54 nmol/L (P<0.001), after acarbose treatment for 12 weeks. 12 out of 14 cases restored ovulation and menstrual cycles after acarbose treatment, among which 4 got pregnant. Conclusion: Acarbose may play a role on reducing postprandial hyperglycemia and HbAic levels, increase ISI and FSG/FI, indirectly reduce serum androgen levels through reducing plasma insulin level and recover ovarian ovulation in PCOS women with postprandial hyperglycemia.展开更多
In-vitro maturation (IVM) of human oocyte is an assisted reproductive technique , which has been used in clinic for more than 10 years since the first report by Cha 1991[1]. Many clinical trials have indicated tha... In-vitro maturation (IVM) of human oocyte is an assisted reproductive technique , which has been used in clinic for more than 10 years since the first report by Cha 1991[1]. Many clinical trials have indicated that IVM technology is not only used to treat infertile women with stubborn polycystic ovarian syn drome (PCOS)[2], to prevent patients from ovarian hyperstimulation syn drome (OHSS)[3],and to rescue the poor developed oocytes in stimu lated cycles , but also to reduce the cost and to avert the side-effects of gonadotropin sti mulation for in-vitro fertilization (IVF). Although there were lots of studies involving to the competence of the immature oocyte from mammalian or human ovar ies to become mature in vitro, the pregnancy rate from IVM is much lower than th at of IVF as reported[4]. This indicates that optimization of IVM remains a challenge. ……展开更多
A new modified A-286 (15Cr-28Ni-1.5Mo-1W-2Ti-Nb-Al)(mass fraction)designated as GH871 i8s characterized by high strengths but low ductility at 650℃ stress rupture and also high crack propagation rates at 650℃ creep ...A new modified A-286 (15Cr-28Ni-1.5Mo-1W-2Ti-Nb-Al)(mass fraction)designated as GH871 i8s characterized by high strengths but low ductility at 650℃ stress rupture and also high crack propagation rates at 650℃ creep and creep/fatigue interaction conditions.For improvement of ductility and crack propagation behaviour,a primary vacuum induction melting and followed electro-slag refining process (VIM+ESR) has been adopted instead of air melting and electro-slag refining process(AIM-ESR). Vacuum melted GH871(VIM+ESR) can keep the high strength level of this alloy and improve the ducility and also decrease crack propagation retes by this alloy purification.It is a good combination of strengthening and toughening for the alloy improvement and development.展开更多
Objective: To evaluate the effect of Xiongshao Capsule (XS, 芎芍胶囊) in preventing clinical and angiographic restenosis after coronary angioplasty or/and stenting. Methods: The total of 108 coronary heart disease pat...Objective: To evaluate the effect of Xiongshao Capsule (XS, 芎芍胶囊) in preventing clinical and angiographic restenosis after coronary angioplasty or/and stenting. Methods: The total of 108 coronary heart disease patients with successful coronary angioplasty or/and stenting were randomly divided into the control group (55 cases, routine treatment) and the XS group (53 cases, routine treatment combined with XS). The recurrence of angina, clinical end-point events, changing of blood-stasis syndrome score (BSSS) and coronary angiography within 6 month after coronary angioplasty or/and stenting were observed. Results: Follow-up angiography was performed in 42 patients including 18 cases in the XS group (restenosis was observed in 7 patients) and 24 cases in the control group (restenosis was observed in 17 patients), there was significant difference between the occurrence of restenosis in XS and that in control group (P<0.05). The occurrence of clinical end-point events (death, nonfatal target lesion myocardial infarction, coronary artery bypass graft surgery, or repeat target-vessel angioplasty) in the XS group (18.8%) was significantly lower than that in the control group (40%)(P<0.05). The recurrent angina was observed in 13 cases in the XS group, there was significant difference as compared with 27 cases in the control group (P<0.05). There was also remarkable significance for the difference of base-line and follow-up BSSS between groups (P<0.01). Logistic multivariate stepwise regress analysis and multivariate regress analysis of the related factors with restenosis confirmed by coronary angiography showed that, the base-line BSSS and the difference of base-line and follow-up BSSS were important influencing factors on the occurrence of restenosis after interventional treatment (P<0.05). Conclusion: XS could markedly reduce the occurrence of angiographic restenosis, clinical end-point events and recurrent angina, improve condition of blood-stasis after coronary angioplasty or/and stenting. The severity of blood-stasis syndrome was an important influencing factor on the occurrence of restenosis. It still needs to be further demonstrated by large-scale, double-blinded, randomized and controlled study.展开更多
文摘Large subunit gene of rubisco (rbcL) of cyanobacteria Arthrospira platensis FACHB341, A. Platensis FACHB439, A. Maxima OUQDSM and Spirulina sp. FACHB440 is cloned, sequenced and characterized. Results show that GC content of the gene in strain Spirulina sp. FACHB440 is higher than that in the others. The alignments based on deduced amino acid sequences indicate that Spirulina sp. FACHB440 is different from that in other three samples of Arthrospira, though they have the same conserved functional sites (95, 98, 121, 124, 221, 257). The nucleotide sequence similarity among the three strains of the genus of Arthrospira (96.5～99.6%) is higher than that between Arthrospira and Spirulina (78.1～78.5%). By comparison of the corresponding sequence of other cyanobacteria, a phylogenetic tree with two clusters is constructed. A. Platensis FACHB341, A. Maxima OUQDSM and A. Platensis FACHB439 form the monophyletic linage, which is fully supported by bootstrap values (1000), while Spirulina sp. FACHB440 and Anabaena sp. PCC7120 cluster in another linage with the bootstrap value of 909.
文摘The cardiovascular system with a lumped parameter model is treated, in which the Starling model is used to simulate left ventricle and the four-element Burattini & Gnudi model is used in the description of arterial system. Moreover, the feedback action of arterial pressure on cardiac cycle is taken into account. The phenomenon of mechanical periodicity (MP) of end diastolic volume (EDV) of left ventricle is successfully simulated by solving a series of one-dimensional discrete nonlinear dynamical equations. The effects of cardiovascular parameters on MP is also discussed.
文摘Summary: Occlusal-maxillo-facial structural change of crossbite malocclusion after orthodontic therapy by modified ACTIVATOR appliance was investigated. Eighty crossbite cases of deciduous dentition and mixed dentition were treated by modified ACTIVATOR. Through pre- and post-treatment analysis of stone model, Schuller’s position X-ray and craniofaciometrics, the change in craniofacial length, width and height in early-phase crossbite malocclusion was studied. The results showed that there was no significant change in the width of maxillary and mandibular dental arch. Maxillary length and protrusion was increased significantly, upper incisors slopped labially. The lower incisors slopped lingually, mental angle decreased more severely. The lower and posterior facial height was increased to normal level.
文摘The most popular estimation method for HMMs is Baum Welch algorithm, which is based on the maximum likelihood(ML) criterion. For other criteria, such as Maximum Mutual Information (MMI) criterion, such an algorithm does not exist. In this case, a gradient based method is considered. With the complexity of the objective function, the computation of the gradients has to be solved before it can be applied to this problem. This paper proposed an implementation method of the gradient based method. Experimental results indicate that this method produces monotonous improvement like Baum Welch algorithm.
文摘Objectives: To investigate the effects of insulin resistance on serum androgen level and ovulation of women with polycystic ovary syndrome (PCOS) and observe clinic role of acarbose in the treatment of hyperinsulinemia, postprandial hyperglycemia and anovulation. Methods: 14 women accompanied by postprandial hyperglycemia with PCOS were administrated by acarbose for 12 weeks.14 age-matched individuals who had similar body mass index and normal menstruation were served as controls. Results: Serum T levels declined significantly from 4.09±1.04 nmol/L to 1.71±0.54 nmol/L (P<0.001), after acarbose treatment for 12 weeks. 12 out of 14 cases restored ovulation and menstrual cycles after acarbose treatment, among which 4 got pregnant. Conclusion: Acarbose may play a role on reducing postprandial hyperglycemia and HbAic levels, increase ISI and FSG/FI, indirectly reduce serum androgen levels through reducing plasma insulin level and recover ovarian ovulation in PCOS women with postprandial hyperglycemia.
文摘 In-vitro maturation (IVM) of human oocyte is an assisted reproductive technique , which has been used in clinic for more than 10 years since the first report by Cha 1991[1]. Many clinical trials have indicated that IVM technology is not only used to treat infertile women with stubborn polycystic ovarian syn drome (PCOS)[2], to prevent patients from ovarian hyperstimulation syn drome (OHSS)[3],and to rescue the poor developed oocytes in stimu lated cycles , but also to reduce the cost and to avert the side-effects of gonadotropin sti mulation for in-vitro fertilization (IVF). Although there were lots of studies involving to the competence of the immature oocyte from mammalian or human ovar ies to become mature in vitro, the pregnancy rate from IVM is much lower than th at of IVF as reported[4]. This indicates that optimization of IVM remains a challenge. ……
文摘A new modified A-286 (15Cr-28Ni-1.5Mo-1W-2Ti-Nb-Al)(mass fraction)designated as GH871 i8s characterized by high strengths but low ductility at 650℃ stress rupture and also high crack propagation rates at 650℃ creep and creep/fatigue interaction conditions.For improvement of ductility and crack propagation behaviour,a primary vacuum induction melting and followed electro-slag refining process (VIM+ESR) has been adopted instead of air melting and electro-slag refining process(AIM-ESR). Vacuum melted GH871(VIM+ESR) can keep the high strength level of this alloy and improve the ducility and also decrease crack propagation retes by this alloy purification.It is a good combination of strengthening and toughening for the alloy improvement and development.
文摘Objective: To evaluate the effect of Xiongshao Capsule (XS, 芎芍胶囊) in preventing clinical and angiographic restenosis after coronary angioplasty or/and stenting. Methods: The total of 108 coronary heart disease patients with successful coronary angioplasty or/and stenting were randomly divided into the control group (55 cases, routine treatment) and the XS group (53 cases, routine treatment combined with XS). The recurrence of angina, clinical end-point events, changing of blood-stasis syndrome score (BSSS) and coronary angiography within 6 month after coronary angioplasty or/and stenting were observed. Results: Follow-up angiography was performed in 42 patients including 18 cases in the XS group (restenosis was observed in 7 patients) and 24 cases in the control group (restenosis was observed in 17 patients), there was significant difference between the occurrence of restenosis in XS and that in control group (P<0.05). The occurrence of clinical end-point events (death, nonfatal target lesion myocardial infarction, coronary artery bypass graft surgery, or repeat target-vessel angioplasty) in the XS group (18.8%) was significantly lower than that in the control group (40%)(P<0.05). The recurrent angina was observed in 13 cases in the XS group, there was significant difference as compared with 27 cases in the control group (P<0.05). There was also remarkable significance for the difference of base-line and follow-up BSSS between groups (P<0.01). Logistic multivariate stepwise regress analysis and multivariate regress analysis of the related factors with restenosis confirmed by coronary angiography showed that, the base-line BSSS and the difference of base-line and follow-up BSSS were important influencing factors on the occurrence of restenosis after interventional treatment (P<0.05). Conclusion: XS could markedly reduce the occurrence of angiographic restenosis, clinical end-point events and recurrent angina, improve condition of blood-stasis after coronary angioplasty or/and stenting. The severity of blood-stasis syndrome was an important influencing factor on the occurrence of restenosis. It still needs to be further demonstrated by large-scale, double-blinded, randomized and controlled study.
