Introduction: Laryngeal cancer is the first cancer of upper aerodigestive tract. Dysphonia, dyspnea and dysphagia are evocative signs. Diagnosis is histological and squamous cell carcinoma is the most common type. The...Introduction: Laryngeal cancer is the first cancer of upper aerodigestive tract. Dysphonia, dyspnea and dysphagia are evocative signs. Diagnosis is histological and squamous cell carcinoma is the most common type. The objective of our study was to discuss epidemiological and anatomo-pathological characteristics of laryngeal cancers diagnosed in different pathological anatomy and cytology (ACP) laboratories of Dakar hospitals. Material and method: This was a retrospective study spanning from January 2013 to December 2018 at the pathological anatomy laboratories of Fann, Aristide Le Dantec and Idrissa Pouye hospitals. All patients with laryngeal cancer confirmed at histology were included. Data collection was based on clinical records of the patients and archives of histological reports of the pathological laboratories. Data analysis was performed under the Excel software. Results: We collected 215 cases of laryngeal cancer. The average age was 58.01 years with extremes of 07 and 94 years. The male sex was predominant with 183 patients (85.12%) against 32 women (14.88%). The most noted risk factor was tobacco which affected 14 patients, or 60.87%. Three patients (13.04%) did not present any alcohol-smoking impregnation. Clinically, dysphonia was noted in 22 patients (26.51%). It was associated with dyspnea in 0.48% of cases and dysphagia in 3.61%. Laryngoscopy was performed in 62 patients or 28.83% of cases, nasofibroscopy in 6.45% of cases. Cord arythenoid fixity was noted in two patients (3.23%) and hypo-mobility in 1 patient (1.61%). The most frequent local extension was involvement of the piriform sinus with 11.29% of cases. Palpable lymphadenopathy reported in 17 patients (20.48%). Pathological examination was performed in all patients after post endoscopic biopsy in 92 patients (42.79%), and after obtaining the operative specimen in 123 cases (57.21%). The three floors affected 76 patients (35.35%). The ulcerative budding aspect most noted concerned 108 patients (60.97%). Histologically, it was a squamous cell carcinoma in 205 patients (95.34%). The most site invaded by the tumor was cricoid cartilage.T4 type was most found (45 patients or 40.90%) followed by the T3 type with 34.55%. There was no lymphadenopathy invasion (Type N0) in 74 patients (67.27%), capsular rupture was reported in five patients (6.77%), no evaluable metastasis in 110 patients (97.27%), and stage IVA predominated in 66 patients (60%). Conclusion: laryngeal cancer is a reality in our contexts, however, its incidence is poorly understood in Senegal. The main risk factors remain tobacco and alcohol. Histology confirms the diagnosis. Its management is multidisciplinary and must be early.展开更多
Introduction: Thyroid cancers are malignant cell proliferations developed at the expense of the thyroid gland, and which can spread from a distance. Most cancers appear in the form of anterior cervical swelling. Ultra...Introduction: Thyroid cancers are malignant cell proliferations developed at the expense of the thyroid gland, and which can spread from a distance. Most cancers appear in the form of anterior cervical swelling. Ultrasound and pathological examination allow the diagnosis of certainty. In Thiès, the studies carried out on thyroid cancers essentially focus on clinico-radiological and therapeutic aspects. We propose, through this study, to describe the epidemiological aspects and the morphological characteristics of thyroid cancers at Thiès Regional Hospital Center. Methodology: This is a retrospective, descriptive and analytical study conducted over a period of 3 years and 6 months, from January 2019 to June 2022. All patients with thyroid cancer confirmed by histological examination were included. Results: The patients who met the inclusion criteria were fourteen in number (14). The average age of patients was 40, 7 +/- 19 years old with extremes of 08 years and 75 years. Our series reports an 86% majority of women against 14% of men, with a sex ratio of 0.17. The isolated thyroid nodule was the most frequent mode of revelation of papillary thyroid cancers in our series, representing 54.6% of patients. The samplings received at the laboratory were essentially total thyroidectomy specimens. The tumor size varied between 1.5 cm and 14 cm. Papillary thyroid carcinoma was the most frequent histological type, with a frequency of 78.6%, followed by gallbladder carcinoma and squamous cell carcinoma. Conclusion: Thyroid cancers affect young subjects and are discovered at a late stage in our context.展开更多
文摘Introduction: Laryngeal cancer is the first cancer of upper aerodigestive tract. Dysphonia, dyspnea and dysphagia are evocative signs. Diagnosis is histological and squamous cell carcinoma is the most common type. The objective of our study was to discuss epidemiological and anatomo-pathological characteristics of laryngeal cancers diagnosed in different pathological anatomy and cytology (ACP) laboratories of Dakar hospitals. Material and method: This was a retrospective study spanning from January 2013 to December 2018 at the pathological anatomy laboratories of Fann, Aristide Le Dantec and Idrissa Pouye hospitals. All patients with laryngeal cancer confirmed at histology were included. Data collection was based on clinical records of the patients and archives of histological reports of the pathological laboratories. Data analysis was performed under the Excel software. Results: We collected 215 cases of laryngeal cancer. The average age was 58.01 years with extremes of 07 and 94 years. The male sex was predominant with 183 patients (85.12%) against 32 women (14.88%). The most noted risk factor was tobacco which affected 14 patients, or 60.87%. Three patients (13.04%) did not present any alcohol-smoking impregnation. Clinically, dysphonia was noted in 22 patients (26.51%). It was associated with dyspnea in 0.48% of cases and dysphagia in 3.61%. Laryngoscopy was performed in 62 patients or 28.83% of cases, nasofibroscopy in 6.45% of cases. Cord arythenoid fixity was noted in two patients (3.23%) and hypo-mobility in 1 patient (1.61%). The most frequent local extension was involvement of the piriform sinus with 11.29% of cases. Palpable lymphadenopathy reported in 17 patients (20.48%). Pathological examination was performed in all patients after post endoscopic biopsy in 92 patients (42.79%), and after obtaining the operative specimen in 123 cases (57.21%). The three floors affected 76 patients (35.35%). The ulcerative budding aspect most noted concerned 108 patients (60.97%). Histologically, it was a squamous cell carcinoma in 205 patients (95.34%). The most site invaded by the tumor was cricoid cartilage.T4 type was most found (45 patients or 40.90%) followed by the T3 type with 34.55%. There was no lymphadenopathy invasion (Type N0) in 74 patients (67.27%), capsular rupture was reported in five patients (6.77%), no evaluable metastasis in 110 patients (97.27%), and stage IVA predominated in 66 patients (60%). Conclusion: laryngeal cancer is a reality in our contexts, however, its incidence is poorly understood in Senegal. The main risk factors remain tobacco and alcohol. Histology confirms the diagnosis. Its management is multidisciplinary and must be early.
文摘Introduction: Thyroid cancers are malignant cell proliferations developed at the expense of the thyroid gland, and which can spread from a distance. Most cancers appear in the form of anterior cervical swelling. Ultrasound and pathological examination allow the diagnosis of certainty. In Thiès, the studies carried out on thyroid cancers essentially focus on clinico-radiological and therapeutic aspects. We propose, through this study, to describe the epidemiological aspects and the morphological characteristics of thyroid cancers at Thiès Regional Hospital Center. Methodology: This is a retrospective, descriptive and analytical study conducted over a period of 3 years and 6 months, from January 2019 to June 2022. All patients with thyroid cancer confirmed by histological examination were included. Results: The patients who met the inclusion criteria were fourteen in number (14). The average age of patients was 40, 7 +/- 19 years old with extremes of 08 years and 75 years. Our series reports an 86% majority of women against 14% of men, with a sex ratio of 0.17. The isolated thyroid nodule was the most frequent mode of revelation of papillary thyroid cancers in our series, representing 54.6% of patients. The samplings received at the laboratory were essentially total thyroidectomy specimens. The tumor size varied between 1.5 cm and 14 cm. Papillary thyroid carcinoma was the most frequent histological type, with a frequency of 78.6%, followed by gallbladder carcinoma and squamous cell carcinoma. Conclusion: Thyroid cancers affect young subjects and are discovered at a late stage in our context.
