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The Role of Prolactin in the Evolution of Prostate Cancer
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作者 Maria Elena Hernandez michael j. wilson 《Open Journal of Urology》 2012年第3期188-197,共10页
Today there is significant information indicating an effect of prolactin on the prostate gland. It has been shown to be involved in mechanisms leading to the synthesis of some proteins such as PSA and cathepsin D, syn... Today there is significant information indicating an effect of prolactin on the prostate gland. It has been shown to be involved in mechanisms leading to the synthesis of some proteins such as PSA and cathepsin D, synthesis of citrate and accumulation of zinc. Also, at the behavioral level, prolactin is known to control some aspects of reproduction, including documentation on the physiology of the prostate and the possibility to trigger pathologies in this sex gland. Although the later still is not clear, there is a correlation between the level of prolactin and the presence of prostate pathologies. Thus, the aim of this review is to show how prolactin is involved in the progression of some pathologies of this male sexual gland. 展开更多
关键词 SECOND MESSENGERS PROLACTIN Receptor ANDROGENS HYPERPROLACTINEMIA
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