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慢乙肝低病毒血症患者继续核苷(酸)类似物治疗的远期临床结局:一项系统评价和Meta分析
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作者 陈和敏 夏明 +1 位作者 郑旭锋 郑积才 《世界华人消化杂志》 CAS 2024年第9期686-694,共9页
背景一线核苷(酸)类似物(nucleos(t)ide analogues,NAs)经治后发生低病毒血症(low-level viremia,LLV)的慢乙肝患者,继续使用NAs治疗的远期临床结局的研究尚缺乏.目的采用系统评价和Meta分析对慢乙肝经一线NAs治疗的LLV患者继续原NAs治... 背景一线核苷(酸)类似物(nucleos(t)ide analogues,NAs)经治后发生低病毒血症(low-level viremia,LLV)的慢乙肝患者,继续使用NAs治疗的远期临床结局的研究尚缺乏.目的采用系统评价和Meta分析对慢乙肝经一线NAs治疗的LLV患者继续原NAs治疗和更换不同NAs治疗方案远期临床结局情况进行评价.方法经计算机检索PubMed、Embase、Web of Science、Cochrane Library数据库和中国知网(CNKI)、万方数据库,选取符合纳入标准的研究,使用R 4.3.1软件对纳入研究数据进行Meta分析.结果最终纳入11篇文献,涉及3153例慢乙肝LLV患者,其中7篇文献进行HBV DNA阴转率定量Meta分析,结果提示更换NAs方案组继续治疗24 wk[RR=4.23,95%CI(2.47,7.24),P<0.01]和48 wk[RR=2.90,95%CI(1.75,4.81),P<0.01]后HBV DNA阴转率明显高于继续原NAs方案组;纳入6篇文献进行HBeAg阴转率的定量Meta分析,更换NAs治疗方案组24 wk HBeAg阴转率高于继续原方案组[RR=2.31,95%CI(1.28,4.19),P<0.01],但48 wk两组HBeAg阴转率差异无统计学意义[RR=1.50,95%CI(0.88,2.54),P=0.13];纳入3篇文献进行终末期肝病发生率的定性系统评价,结果显示继续NAs治疗的LLV组患者远期终末期肝病发生率均高于维持病毒学应答(maintain virological response,MVR)组,差异均具有统计学意义(P<0.05).结论更换NAs治疗方案可提高慢乙肝LLV患者HBV DNA阴转率和HBeAg阴转率,但继续NAs方案治疗的慢乙肝LLV患者远期终末期肝病发生率较MVR患者高. 展开更多
关键词 慢性乙型肝炎 低病毒血症 核苷(酸)类药物 临床结局 META分析
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数字普惠金融助力牧区振兴的路径选择
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作者 包玉珍 明霞 苏雅拉图 《安徽农业科学》 CAS 2024年第8期240-242,共3页
数字普惠金融具有减少金融服务成本、提升金融服务效率等优点,是改善收入不均衡,加强金融包容性的有效方法。在乡村振兴战略背景下发展牧区数字普惠金融,具有促进牧民消费升级、激发牧民创新创业的活力、改善牧区社会信用环境等重要意... 数字普惠金融具有减少金融服务成本、提升金融服务效率等优点,是改善收入不均衡,加强金融包容性的有效方法。在乡村振兴战略背景下发展牧区数字普惠金融,具有促进牧民消费升级、激发牧民创新创业的活力、改善牧区社会信用环境等重要意义。分析了增强金融知识教育并提高牧民金融素养、优化牧区数字金融基础设施建设、搞好数字普惠金融生态建设等数字普惠金融助力牧区振兴的路径选择。 展开更多
关键词 数字普惠金融 牧区振兴 路径分析
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An MPI parallel DEM-IMB-LBM framework for simulating fluid-solid interaction problems 被引量:2
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作者 ming xia Liuhong Deng +3 位作者 Fengqiang Gong Tongming Qu Y.T.Feng Jin Yu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2219-2231,共13页
The high-resolution DEM-IMB-LBM model can accurately describe pore-scale fluid-solid interactions,but its potential for use in geotechnical engineering analysis has not been fully unleashed due to its prohibitive comp... The high-resolution DEM-IMB-LBM model can accurately describe pore-scale fluid-solid interactions,but its potential for use in geotechnical engineering analysis has not been fully unleashed due to its prohibitive computational costs.To overcome this limitation,a message passing interface(MPI)parallel DEM-IMB-LBM framework is proposed aimed at enhancing computation efficiency.This framework utilises a static domain decomposition scheme,with the entire computation domain being decomposed into multiple subdomains according to predefined processors.A detailed parallel strategy is employed for both contact detection and hydrodynamic force calculation.In particular,a particle ID re-numbering scheme is proposed to handle particle transitions across sub-domain interfaces.Two benchmarks are conducted to validate the accuracy and overall performance of the proposed framework.Subsequently,the framework is applied to simulate scenarios involving multi-particle sedimentation and submarine landslides.The numerical examples effectively demonstrate the robustness and applicability of the MPI parallel DEM-IMB-LBM framework. 展开更多
关键词 Discrete element method(DEM) Lattice Boltzmann method(LBM) Immersed moving boundary(IMB) Multi-cores parallelization Message passing interface(MPI) CPU Submarine landslides
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A particle-resolved heat-particle-fluid coupling model by DEM-IMB-LBM 被引量:1
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作者 ming xia Jinlong Fu +2 位作者 Y.T.Feng Fengqiang Gong Jin Yu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2267-2281,共15页
Multifield coupling is frequently encountered and also an active area of research in geotechnical engineering.In this work,a particle-resolved direct numerical simulation(PR-DNS)technique is extended to simulate parti... Multifield coupling is frequently encountered and also an active area of research in geotechnical engineering.In this work,a particle-resolved direct numerical simulation(PR-DNS)technique is extended to simulate particle-fluid interaction problems involving heat transfer at the grain level.In this extended technique,an immersed moving boundary(IMB)scheme is used to couple the discrete element method(DEM)and lattice Boltzmann method(LBM),while a recently proposed Dirichlet-type thermal boundary condition is also adapted to account for heat transfer between fluid phase and solid particles.The resulting DEM-IBM-LBM model is robust to simulate moving curved boundaries with constant temperature in thermal flows.To facilitate the understanding and implementation of this coupled model for non-isothermal problems,a complete list is given for the conversion of relevant physical variables to lattice units.Then,benchmark tests,including a single-particle sedimentation and a two-particle drafting-kissing-tumbling(DKT)simulation with heat transfer,are carried out to validate the accuracy of our coupled technique.To further investigate the role of heat transfer in particle-laden flows,two multiple-particle problems with heat transfer are performed.Numerical examples demonstrate that the proposed coupling model is a promising high-resolution approach for simulating the heat-particle-fluid coupling at the grain level. 展开更多
关键词 Particle-fluid interaction Heat transfer Discrete element method(DEM) Lattice Boltzmann method(LBM) Dirichlet-type thermal boundary Direct numerical simulation
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血清叉头框D1在鼻咽癌患者中的表达及其与放疗后复发转移关系研究
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作者 明霞 刘伟 《陕西医学杂志》 CAS 2024年第11期1495-1499,共5页
目的:探讨血清叉头框D1(FOXD1)在鼻咽癌(NPC)患者中的表达及其与放疗后复发转移的关系。方法:选取本院NPC患者235例为NPC组,另选取同期本院体检健康志愿者246例为对照组。比较两组一般资料及血清FOXD1水平。分析血清FOXD1表达与NPC患者... 目的:探讨血清叉头框D1(FOXD1)在鼻咽癌(NPC)患者中的表达及其与放疗后复发转移的关系。方法:选取本院NPC患者235例为NPC组,另选取同期本院体检健康志愿者246例为对照组。比较两组一般资料及血清FOXD1水平。分析血清FOXD1表达与NPC患者临床病理特征的关系。对化疗后NPC患者随访3年,记录复发转移情况。采用Cox回归分析NPC患者放疗后复发转移的影响因素。采用Spearman法分析血清FOXD1水平与肿瘤分化程度及EB病毒感染的相关性。绘制受试者工作特征(ROC)曲线分析血清FOXD1对NPC患者放疗后复发转移的预测价值。结果:NPC组FOXD1水平高于对照组(P<0.05)。NPC患者血清FOXD1表达与肿瘤分化程度、TNM分期、颈部淋巴结转移、肿瘤浸润深度、颅底侵犯、EB病毒感染有关(均P<0.05)。肿瘤低分化、EB病毒感染阳性及FOXD1高表达是NPC患者放疗后复发转移的独立危险因素(均P<0.05)。血清FOXD1水平与肿瘤分化程度呈负相关,与EB病毒感染呈正相关(均P<0.05)。FOXD1对NPC患者放疗后复发转移具有一定的预测价值(P<0.05)。结论:FOXD1在NPC患者血清中表达水平升高,与临床病理特征有关,是患者放疗后复发转移的危险因素,对放疗后复发转移具有一定的预测价值。 展开更多
关键词 鼻咽癌 叉头框D1 复发转移 临床病理特征 影响因素 预测价值
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医护人员抑郁症状与心理弹性的网络分析
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作者 明霞 杨翠 +2 位作者 邓媛媛 张慧 陈瑶 《卫生职业教育》 2024年第18期104-109,共6页
目的以医护人员为研究对象,构建抑郁症状和心理弹性之间的网络模型,并识别核心症状和桥梁症状。方法采用便利抽样法,使用一般资料问卷、16项抑郁症状快速自评量表和心理弹性量表简版,对四川省三级医院的826名医护人员进行调查。通过网... 目的以医护人员为研究对象,构建抑郁症状和心理弹性之间的网络模型,并识别核心症状和桥梁症状。方法采用便利抽样法,使用一般资料问卷、16项抑郁症状快速自评量表和心理弹性量表简版,对四川省三级医院的826名医护人员进行调查。通过网络分析法,探究抑郁症状和心理弹性间的复杂关系。结果抑郁症状维度中“精力水平”(强度1.22)和心理弹性条目中“当处理生活中的挑战和困难时,我想我是一个坚强的人”(强度1.12)、条目“我不会轻易被失望打败”(强度1.09)的强度中心性较高;抑郁症状维度“感到悲伤”(桥强度0.101)、“精力水平”(桥强度0.054)和心理弹性条目“在生病、受难或苦难之后,我很容易就能恢复过来”(桥强度0.107)、“我能够处理一些不愉快或痛苦的感觉,例如悲伤、害怕和生气”(桥强度0.062)的桥强度中心性较高;网络结构的相关稳定性系数分别为0.75和0.28,表示具有较好的稳定性。结论网络分析法为医护人员抑郁和心理弹性的症状管理提供了更具体的干预路径,未来有待开展纵向调查,进一步探索症状间的因果关系。 展开更多
关键词 医护人员 抑郁症状 心理弹性 网络分析
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In-situ measurement via the flow-through method and numerical simulations for radon exhalation during measurements of the radon exhalation rate
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作者 ming xia Yong-Jun Ye +2 位作者 Shan-Wei Shang Ting Yu Dai-Jia Chen 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第7期192-207,共16页
Small-scale measurements of the radon exhalation rate using the flow-through and closed-loop methods were conducted on the surface of a uranium tailing pond to better understand the differences between the two methods... Small-scale measurements of the radon exhalation rate using the flow-through and closed-loop methods were conducted on the surface of a uranium tailing pond to better understand the differences between the two methods.An abnormal radon exhalation behavior was observed,leading to computational fluid dynamics(CFD)-based simulations in which dynamic radon migration in a porous medium and accumulation chamber was considered.Based on the in-situ experimental and numerical simulation results,variations in the radon exhalation rate subject to permeability,flow rate,and insertion depth were quantified and analyzed.The in-situ radon exhalation rates measured using the flow-through method were higher than those measured using the closed-loop method,which could be explained by the negative pressure difference between the inside and outside of the chamber during the measurements.The consistency of the variations in the radon exhalation rate between the experiments and simulations suggests the reliability of CFD-based techniques in obtaining the dynamic evolution of transient radon exhalation rates for diffusion and convection at the porous medium-air interface.The synergistic effects of the three factors(insertion depth,flow rate,and permeability)on the negative pressure difference and measured exhalation rate were quantified,and multivariate regression models were established,with positive correlations in most cases;the exhalation rate decreased with increasing insertion depth at a permeability of 1×10^(−11) m^(2).CFD-based simulations can provide theoretical guidance for improving the flow-through method and thus achieve accurate measurements. 展开更多
关键词 Radon exhalation FLOW-THROUGH Numerical simulation Accumulation chamber Multivariate regression
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Indirect neutron radiography experiment on dummy nuclear fuel rods for pressurized water reactors at CMRR
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作者 Yong Sun Qi-Biao Wang +11 位作者 Peng-Cheng Li ming xia Bin Liu He-Yong Huo Wei Yin Yang Wu Sheng Wang Chao Cao Xin Yang Run-Dong Li Hang Li Bin Tang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第11期13-27,共15页
Nuclear energy is a vital source of clean energy that will continue to play an essential role in global energy production for future generations.Nuclear fuel rods are core components of nuclear power plants,and their ... Nuclear energy is a vital source of clean energy that will continue to play an essential role in global energy production for future generations.Nuclear fuel rods are core components of nuclear power plants,and their safe utilization is paramount.Due to its inherent high radioactivity,indirect neutron radiography(INR)is currently the only viable technology for irradiated nuclear fuel rods in the field of energy production.This study explores the experimental technique of indirect neutron computed tomography(INCT)for radioactive samples.This project includes the development of indium and dysprosium conversion screens of different thicknesses and conducts resolution tests to assess their performance.Moreover,pressurized water reactor(PWR)dummy nuclear fuel rods have been fabricated by self-developing substitute materials for cores and outsourcing of mechanical processing.Experimental research on the INR is performed using the developed dummy nuclear fuel rods.The sparse reconstruction technique is used to reconstruct the INR results of 120 pairs of dummy nuclear fuel rods at different angles,achieving a resolution of 0.8 mm for defect detection using INCT. 展开更多
关键词 Conversion screen DYSPROSIUM Indirect neutron computed tomography Dummy nuclear fuel rods
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三级甲等医院ICU护士职业死亡回避现状及影响因素
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作者 许英 杨昌美 +6 位作者 郭声敏 刘梦婕 曾梁楠 李倩茜 易子涵 明霞 梁瑞晨 《护理研究》 北大核心 2024年第16期2916-2921,共6页
目的:调查三级甲等医院ICU护士职业死亡回避现状及其影响因素,为干预方案的制定提供参考。方法:采用一般资料调查表、ICU护士职业死亡回避量表、死亡应对量表、死亡焦虑量表对12所三级甲等医院的464名ICU护士进行调查。结果:ICU护士职... 目的:调查三级甲等医院ICU护士职业死亡回避现状及其影响因素,为干预方案的制定提供参考。方法:采用一般资料调查表、ICU护士职业死亡回避量表、死亡应对量表、死亡焦虑量表对12所三级甲等医院的464名ICU护士进行调查。结果:ICU护士职业死亡回避总分为(37.39±8.61)分;年龄、宗教信仰、在校期间接受过死亡教育、近1年内参加过死亡教育培训、对ICU护理工作的态度、尸体护理次数、死亡应对、死亡焦虑是ICU护士职业死亡回避的主要影响因素(P<0.05)。结论:ICU护士职业死亡回避处于中等水平,影响因素较多。护理管理者可针对影响因素进行干预,降低ICU护士职业死亡回避水平,提升ICU护理质量。 展开更多
关键词 ICU护士 职业死亡回避 死亡应对 死亡焦虑 死亡教育 影响因素
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Numerical simulations for radon migration and exhalation behavior during measuring radon exhalation rate with closed-loop method
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作者 ming xia Yong-Jun Ye Shu-Yuan Liu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第1期81-95,共15页
Accurate measurements of the radon exhalation rate help identify and evaluate radon risk regions in the environment.Among these measurement methods,the closed-loop method is frequently used.However,traditional experim... Accurate measurements of the radon exhalation rate help identify and evaluate radon risk regions in the environment.Among these measurement methods,the closed-loop method is frequently used.However,traditional experiments are insufficient or cannot analyze the radon migration and exhalation patterns at the gas–solid interface in the accumulation chamber.The CFD-based technique was applied to predict the radon concentration distribution in a limited space,allowing radon accumulation and exhalation inside the chamber intuitively and visually.In this study,three radon exhalation rates were defined,and two structural ventilation tubes were designed for the chamber.The consistency of the simulated results with the variation in the radon exhalation rate in a previous experiment or analytical solution was verified.The effects of the vent tube structure and flow rate on the radon uniformity in the chamber;permeability,insertion depth,and flow rate on the radon exhalation rate and the effective diffusion coefficient on back-diffusion were investigated.Based on the results,increasing the inser-tion depth from 1 to 5 cm decreased the effective decay constant by 19.55%,whereas the curve-fitted radon exhalation rate decreased(lower than the initial value)as the deviation from the initial value increased by approximately 7%.Increasing the effective diffusion coefficient from 2.77×10^(-7) to 7.77×10^(-6) m^(2) s^(-1) made the deviation expand from 2.14 to 15.96%.The conclusion is that an increased insertion depth helps reduce leakage in the chamber,subject to notable back-diffusion,and that the closed-loop method is reasonably used for porous media with a low effective diffusion coefficient in view of the back-diffusion effect.The CFD-based simulation is expected to provide guidance for the optimization of the radon exhalation rate measurement method and,thus,the accurate measurement of the radon exhalation rate. 展开更多
关键词 Radon exhalation Numerical simulation Accumulation chamber
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Sepsis one-hour bundle management combined with psychological intervention on negative emotion and sleep quality in patients with sepsis
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作者 ming xia Guang-Yan Dong +2 位作者 Shi-Chao Zhu Huan-Min Xing Li-ming Li 《World Journal of Psychiatry》 SCIE 2024年第2期266-275,共10页
BACKGROUND Sepsis is a serious infectious disease caused by various systemic inflammatory responses and is ultimately life-threatening.Patients usually experience depression and anxiety,which affect their sleep qualit... BACKGROUND Sepsis is a serious infectious disease caused by various systemic inflammatory responses and is ultimately life-threatening.Patients usually experience depression and anxiety,which affect their sleep quality and post-traumatic growth levels.AIM To investigate the effects of sepsis,a one-hour bundle(H1B)management was combined with psychological intervention in patients with sepsis.METHODS This retrospective analysis included 300 patients with sepsis who were admitted to Henan Provincial People’s Hospital between June 2022 and June 2023.According to different intervention methods,the participants were divided into a simple group(SG,n=150)and combined group(CG,n=150).H1B management was used in the SG and H1B management combined with psychological intervention was used in the CG.The changes of negative emotion,sleep quality and post-traumatic growth and prognosis were compared between the two groups before(T0)and after(T1)intervention.RESULTS After intervention(T1),the scores of the Hamilton Anxiety scale and Hamilton Depression scale in the CG were significantly lower than those in the SG(P<0.001).Sleep time,sleep quality,sleep efficiency,daytime dysfunction,sleep disturbance dimension score,and the total score in the CG were significantly lower than those in the SG(P<0.001).The appreciation of life,mental changes,relationship with others,personal strength dimension score,and total score of the CG were significantly higher than those of the SG(P<0.001).The scores for mental health,general health status,physiological function,emotional function,physical pain,social function,energy,and physiological function in the CG were significantly higher than those in the SG(P<0.001).The mechanical ventilation time,intensive care unit stay time,and 28-d mortality of the CG were significantly lower than those of the SG(P<0.05).CONCLUSION H1B management combined with psychological intervention can effectively alleviate the negative emotions of patients with sepsis and increase their quality of sleep and life. 展开更多
关键词 Cluster management Psychological intervention SEPSIS Negative emotions Sleep quality Post-traumatic growth
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耳鼻喉手术用复合缝合线材料性能试验及应用效果
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作者 明霞 何文 +1 位作者 肖宝珠 欧阳凡 《粘接》 CAS 2024年第5期79-82,共4页
为提高手术缝合线的力学性能和应用效果,试验利用改性丝素蛋白溶液和硅溶胶,结合脱胶缝合线,制备了一种外科手术缝合用的复合线,并对其性能以及应用效果进行研究。结果表明,与普通缝合线相比,该复合线在应力-应变曲线中的最大应力、应... 为提高手术缝合线的力学性能和应用效果,试验利用改性丝素蛋白溶液和硅溶胶,结合脱胶缝合线,制备了一种外科手术缝合用的复合线,并对其性能以及应用效果进行研究。结果表明,与普通缝合线相比,该复合线在应力-应变曲线中的最大应力、应变均提高,分别达到435.6MPa、23.3%,力学性能良好;从模拟组织中拉出的最大力最大,为2.15N,提高70.63%,在组织缝合中的锚定作用较好;在蛋白酶降解5d后剩余质量为18.26%,生物降解性能良好;这种复合线在外科手术切口缝合应用中切口感染率较低,为2.5%,且切口愈合优良率达到77.5%,应用效果较好。可以适用于外科手术切口缝合。 展开更多
关键词 缝合线 丝素蛋白 力学性能 降解性能 切口感染率
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颅内动脉瘤介入术病人自我管理的最佳证据总结
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作者 许英 曾梁楠 +4 位作者 张洪霞 明霞 唐容 李倩茜 杨昌美 《全科护理》 2024年第4期595-600,共6页
目的:系统检索、评价和总结颅内动脉瘤介入术病人自我管理的相关证据,为临床制订基于证据的颅内动脉瘤介入术病人自我管理干预方案提供依据。方法:系统检索国内外相关指南网站、专业学会网站及PubMed、中国知网等数据库中关于颅内动脉... 目的:系统检索、评价和总结颅内动脉瘤介入术病人自我管理的相关证据,为临床制订基于证据的颅内动脉瘤介入术病人自我管理干预方案提供依据。方法:系统检索国内外相关指南网站、专业学会网站及PubMed、中国知网等数据库中关于颅内动脉瘤介入术病人自我管理的相关指南、专家共识、临床决策、系统评价等,检索时限为建库至2023年1月25日。结果:共纳入13篇文献,其中指南5篇,最佳实践1篇,专家共识5篇,系统评价2篇。从颅内动脉瘤介入术病人信息管理、围术期管理、症状与疾病管理、日常生活管理、情绪管理、社会管理、随访管理7个方面总结出26条最佳证据。结论:颅内动脉瘤介入术病人自我管理的最佳证据总结具有科学性和规范性,医护人员可结合临床情境,为颅内动脉瘤介入术病人提供个性化的自我管理指导。 展开更多
关键词 颅内动脉瘤 血管内治疗 自我管理 证据总结 循证护理
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Particle simulation of the failure process of brittle rock under triaxial compression 被引量:12
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作者 ming xia Ke-ping Zhou 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2010年第5期507-513,共7页
In order to investigate the failure process of brittle rock under triaxial compression through both experimental and numerical approaches, the particle simulation method was used in numerical simulations and the simul... In order to investigate the failure process of brittle rock under triaxial compression through both experimental and numerical approaches, the particle simulation method was used in numerical simulations and the simulated results were compared with those of the experiment. The numerical simulation results, such as fracture propagation, microcrack distribution, stress-strain response, and damage patterns, were discussed in detail. The simulated results under various confining pressures (0-60 MPa) are in good agreement with the experimental results. The simulated results reveal that rock failure is caused by axial splitting under uniaxial compression. As the confining pressure increases, rock failure occurs in a few localized shear planes and the rock mechanical behavior is changed from brittle to ductile. Consequently, the peak failure strength, microcrack numbers, and the shear plane angle increase, but the ratio of tensile to shear microcracks decreases. The damage formation during the compression simulations indicates that the particle simulation method can produce similar behaviors as those observed through laboratory compression tests. 展开更多
关键词 rock mechanics compression testing FAILURE fracture modes SIMULATION MICROCRACKS
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薄型子宫内膜合并排卵功能障碍性不孕症辨治心得
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作者 关婷婷 蒋琼 +1 位作者 明霞 程航 《中国中医药现代远程教育》 2023年第18期145-148,共4页
薄型子宫内膜、排卵功能障碍是女性不孕症的常见病因,中医治疗方法为补肾调经助孕。根据女性月经周期不同阶段的生理特点,分期进行调经治疗可有效促进子宫内膜生长,促进卵泡发育并排卵。中医外治法,例如针灸治疗(包括针刺、艾灸、穴位... 薄型子宫内膜、排卵功能障碍是女性不孕症的常见病因,中医治疗方法为补肾调经助孕。根据女性月经周期不同阶段的生理特点,分期进行调经治疗可有效促进子宫内膜生长,促进卵泡发育并排卵。中医外治法,例如针灸治疗(包括针刺、艾灸、穴位埋线、梅花针叩刺、耳穴治疗等)、中药外敷治疗、中药保留灌肠治疗等,可增强内治法的效果、弥补内治法的不足,中药内服和中医外治法联合使用治疗薄型子宫内膜合并排卵功能障碍性不孕症效果显著,成功率高。 展开更多
关键词 薄型子宫内膜 排卵功能障碍 不孕症 中医药疗法
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脐姜灸在寒凝血瘀型月经过少中的应用
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作者 程航 蒋琼 +1 位作者 明霞 关婷婷 《中国中医药现代远程教育》 2023年第19期128-131,共4页
月经过少是一种常见的妇科疾病症状,虽短时间内不会对身体产生很大的危害,但长期如此会导致严重的内分泌疾病,如闭经、不孕症、卵巢早衰等,应该尽早治疗。临床上中西医治疗月经过少的方式多种多样,如雌孕激素序贯疗法、中药内服、针刺... 月经过少是一种常见的妇科疾病症状,虽短时间内不会对身体产生很大的危害,但长期如此会导致严重的内分泌疾病,如闭经、不孕症、卵巢早衰等,应该尽早治疗。临床上中西医治疗月经过少的方式多种多样,如雌孕激素序贯疗法、中药内服、针刺、艾灸、穴位贴敷等均能产生不同程度的效果,但大部分费用较高,治疗时间长,对于经济困难的患者来说很难坚持。脐姜灸有简、便、廉、效的优点,在治疗月经病尤其是治疗寒凝血瘀型月经过少方面效果显著,被广大女性所接受。 展开更多
关键词 月经过少 寒凝血瘀证 脐姜灸 中医外治法
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宫腔放置子宫球囊支架或导尿管预防中重度宫腔粘连分离术后再粘连疗效 被引量:31
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作者 王燕 明霞 蒋琼 《中国计划生育学杂志》 2019年第1期33-35,39,共4页
目的:观察中重度宫腔粘连宫腔镜冷刀分离术后,宫腔放置子宫球囊支架或球囊导尿管预防再粘连疗效。方法:纳入2016年6月—2017年10月接受宫腔镜冷刀分离术的80例中重度宫腔粘连患者,随机均分为两组,支架组术后放置子宫球囊支架,导尿管组... 目的:观察中重度宫腔粘连宫腔镜冷刀分离术后,宫腔放置子宫球囊支架或球囊导尿管预防再粘连疗效。方法:纳入2016年6月—2017年10月接受宫腔镜冷刀分离术的80例中重度宫腔粘连患者,随机均分为两组,支架组术后放置子宫球囊支架,导尿管组放置球囊导尿管。术后3个月复查疗效,观察术后1、3个月、6个月时再粘连情况,统计术后6个月内周期性腹痛改善及妊娠情况。结果:术后3个月两组临床疗效对比无差异,术后6个月内支架组再粘连发生率(52.5%)与导尿管组(57.5%)对比无差异,两组周期性腹痛改善情况及妊娠情况对比无差异(均P>0.05)。结论:对中重度宫腔粘连患者,在宫腔镜冷刀分离术后放置球囊导尿管与放置子宫球囊支架有相近的疗效及再粘连预防效果。 展开更多
关键词 中重度宫腔粘连 宫腔镜冷刀分离术 子宫球囊支架 球囊导尿管
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米非司酮联合桃红四物汤治疗产后胎盘残留及对机体应激反应的影响 被引量:12
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作者 明霞 王燕 蒋琼 《中国计划生育学杂志》 2020年第12期1979-1982,共4页
目的:观察米非司酮联合桃红四物汤治疗产后胎盘残留效果及对机体应激反应的影响。方法:选取2016年8月—2018年5月本院收治的产后胎盘残留患者138例,随机单双编号后分为中西药组(n=69)与西药组(n=69)。两组均予米非司酮治疗,中西药组在... 目的:观察米非司酮联合桃红四物汤治疗产后胎盘残留效果及对机体应激反应的影响。方法:选取2016年8月—2018年5月本院收治的产后胎盘残留患者138例,随机单双编号后分为中西药组(n=69)与西药组(n=69)。两组均予米非司酮治疗,中西药组在此基础上联合桃红四物汤治疗。观察两组治疗前后胎盘残留面积、人绒毛膜促性腺激素(β-hCG)、血性恶露持续时间、子宫收缩期、盆腔感染及机体应激反应。结果:治疗后中西药组治疗总有效率(97.1%)高于西药组(84.1%),胎盘残留面积(2.92±0.96cm^3)小于西药组(14.38±2.64cm^3),β-hCG水平(26.03±8.15 mIU/ml)低于西药组(70.65±13.88 mIU/ml),血性恶露持续时间(10.2±1.9d)短于对照组(16.4±3.8d),子宫收缩期体积(128.6±35.0cm^3)小于对照组(400.3±62.4cm^3)(均P<0.05),盆腔感染率(4.4%)与西药组(8.7%)无差异(P>0.05);治疗后超氧化物歧化酶、过氧化氢酶两组均较治疗前降低但中西药组高于西药组,活性氧簇两组均较治疗前升高但中西药组低于西药组(P<0.05)。结论:米非司酮联合桃红四物汤治疗产后胎盘残留疗效更佳,可更好地减少胎盘残留面积,促进子宫恢复,减少盆腔感染,减轻患者机体应激反应。 展开更多
关键词 产后胎盘残留 米非司酮 桃红四物汤 子宫恢复 机体应激
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双J管远端栓线在输尿管中下段结石内镜术后的应用尝试 被引量:7
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作者 林长明 夏明 +1 位作者 胡富勇 徐秀民 《中国内镜杂志》 2019年第3期44-47,共4页
目的研究输尿管镜检和/或中下段结石内镜碎石术后留置双J管的时间,以及短期拔管方法的改进,尝试无创、快速、简单和经济的方式。方法选择2015年6月-2017年4月输尿管内镜手术患者71例,分为两组。实验组35例,为输尿管镜中下段结石患者,术... 目的研究输尿管镜检和/或中下段结石内镜碎石术后留置双J管的时间,以及短期拔管方法的改进,尝试无创、快速、简单和经济的方式。方法选择2015年6月-2017年4月输尿管内镜手术患者71例,分为两组。实验组35例,为输尿管镜中下段结石患者,术毕留置双J管,双J管远端栓丝线,丝线另一端固定于体外;对照组36例,为输尿管全段结石患者,常规置入双J管。结果实验组35例术后第5天拔除双J管,2例拔除失败;对照组常规术后3或4周拔管。比较实验组留置双J管期间,两组在疼痛数字评分(NRS)、术后血尿时间和膀胱刺激征上,差异均无统计学意义(P>0.05)。结论输尿管镜检和/或中下段结石内镜碎石术后,留置双J管的时间可以在5 d;双J管远端栓线不增加置管期间患者的不适症状,且拔管安全、简单、快速、无经济负担,可在此类术式中推行。 展开更多
关键词 输尿管镜术后 双J管 置管时间 栓线 拔管
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接纳承诺疗法在癌症患者中的应用进展 被引量:16
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作者 李倩茜 曾梁楠 +7 位作者 梁瑞晨 孙子科技木 向瑞芳 陈超逸 张丽英 明霞 唐容 杨昌美 《护理管理杂志》 2022年第1期44-48,共5页
接纳承诺疗法运用于癌症领域的干预研究在国内还处于起步阶段,文章对接纳承诺疗法的基本理论、作用机制和测评工具,以及作用于癌症患者的干预方法和临床效果进行总结,为我国癌症领域应用接纳承诺疗法的发展提供经验总结和借鉴。
关键词 癌症 接纳承诺疗法 认知疗法 正念
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