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Explosion resistance performance of reinforced concrete box girder coated with polyurea:Model test and numerical simulation
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作者 Guangpan Zhou Rong wang +2 位作者 mingyang wang Jianguo Ding Yuye Zhang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期1-18,共18页
To study the anti-explosion protection effect of polyurea coating on reinforced concrete box girder,two segmental girder specimens were made at a scale of 1:3,numbered as G(without polyurea coating)and PCG(with polyur... To study the anti-explosion protection effect of polyurea coating on reinforced concrete box girder,two segmental girder specimens were made at a scale of 1:3,numbered as G(without polyurea coating)and PCG(with polyurea coating).The failure characteristics and dynamic responses of the specimens were compared through conducting explosion tests.The reliability of the numerical simulation using LS-DYNA software was verified by the test results.The effects of different scaled distances,reinforcement ratios,concrete strengths,coating thicknesses and ranges of polyurea were studied.The results show that the polyurea coating can effectively enhance the anti-explosion performance of the girder.The top plate of middle chamber in specimen G forms an elliptical penetrating hole,while that in specimen PCG only shows a very slight local dent.The peak vertical displacement and residual displacement of PCG decrease by 74.8% and 73.7%,respectively,compared with those of specimen G.For the TNT explosion with small equivalent,the polyurea coating has a more significant protective effect on reducing the size of fracture.With the increase of TNT equivalent,the protective effect of polyurea on reducing girder displacement becomes more significant.The optimal reinforcement ratio,concrete strength,thickness and range of polyurea coating were also drawn. 展开更多
关键词 Explosive load Explosion resistance performance Model test POLYUREA Concrete box girder Numerical simulation
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Ballistic performance of spaced multi-ply soft fabrics: Experimental and numerical investigation
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作者 Zhongwei Zhang Xiaoning Yang +4 位作者 Yuan Lin Ziming Xiong Yuhang Xiang Yi Zhou mingyang wang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第4期143-155,共13页
It has been reported that the ply gap influences the ballistic resistance of spaced multi-ply fabric systems,but its working mechanism was not well-understood. This paper reports the experimental and numerical approac... It has been reported that the ply gap influences the ballistic resistance of spaced multi-ply fabric systems,but its working mechanism was not well-understood. This paper reports the experimental and numerical approaches and results of an investigation on the mechanisms that enable the improved ballistic performance of spaced multi-ply systems. Penetration tests were performed over a range of impact velocities ranging from 200 m/s to 400 m/s. The results confirmed that the ply gap is beneficial to the energy absorption capability of the systems. This is because the front plies tend to absorb more energy when they are not immediately constrained by the rear plies. During a ballistic event, the gap relieves the reflection of the compressive pulse, prolonging the projectile engagement time with the front plies;on the other hand, the rear plies become increasingly less active in dissipating energy as the gap increases.When the gap is sufficiently widened to avoid any interference between the plies before the failure of the front ply, the responses of the whole system no longer vary. It was also found that the ballistic performance of the spaced systems is influenced by ply thickness, impact velocity, and the stacking order of the ply gap. 展开更多
关键词 Energy absorption capability Ply gap Ballistic performance The front ply The rear ply
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Dynamically triggered seismicity on a tectonic scale:A review
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作者 Chengzhi Qi mingyang wang +2 位作者 Gevorg Kocharyan Artem Kunitskikh Zefan wang 《Deep Underground Science and Engineering》 2024年第1期1-24,共24页
Earthquakes triggered by dynamic disturbances have been confirmed by numerous observations and experiments.In the past several decades,earthquake triggering has attracted increasing attention of scholars in relation t... Earthquakes triggered by dynamic disturbances have been confirmed by numerous observations and experiments.In the past several decades,earthquake triggering has attracted increasing attention of scholars in relation to exploring the mechanism of earthquake triggering,earthquake prediction,and the desire to use the mechanism of earthquake triggering to reduce,prevent,or trigger earthquakes.Natural earthquakes and large‐scale explosions are the most common sources of dynamic disturbances that trigger earthquakes.In the past several decades,some models have been developed,including static,dynamic,quasi‐static,and other models.Some reviews have been published,but explosiontriggered seismicity was not included.In recent years,some new results on earthquake triggering have emerged.Therefore,this paper presents a new review to reflect the new results and include the content of explosion‐triggered earthquakes for the reference of scholars in this area.Instead of a complete review of the relevant literature,this paper primarily focuses on the main aspects of dynamic earthquake triggering on a tectonic scale and makes some suggestions on issues that need to be resolved in this area in the future. 展开更多
关键词 dynamic disturbances dynamic models problems for future research quasi‐static models static models triggered seismicity
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Experimental study on the irreversible displacement evolution and energy dissipation characteristics of disturbance instability of regular joints
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作者 Jianan Yang Pengxian Fan +2 位作者 mingyang wang Jie Li Lu Dong 《Deep Underground Science and Engineering》 2023年第1期20-36,共17页
To investigate the disturbance-induced shear instability mechanism of structural catastrophe in the deep rock mass,MTS 815 material testing machine was used to carry out quasi-static loading tests and disturbance shea... To investigate the disturbance-induced shear instability mechanism of structural catastrophe in the deep rock mass,MTS 815 material testing machine was used to carry out quasi-static loading tests and disturbance shear tests on symmetrical regular dentate joints of two materials at three undulation angles under specific initial static stress,disturbance frequency,and peak value.The test results indicate that:(i)the total ultimate instability displacement is only related to the intrinsic properties of the joints but not to the initial static stress and disturbance parameters;(ii)the cumulative irreversible displacement required for the disturbance instability conforms to the logistic inverse function relationship with the number of disturbances,displaying the variation trend of“rapid increase in the front,stable in the middle,and sudden increase in the rear”;(iii)the accumulation of plastic deformation energy is consistent with the evolution law of irreversible displacement of joints and the overall proportion of hysteretic energy is not large;(iv)the dissipated energy required for the instability of each group of joints is basically the same under various disturbance conditions,and this energy is mainly controlled by the initial shear stress and has no connection with the disturbance parameters.The stability of the total disturbance deformation and the disturbance energy law of the joints revealed in the tests provide data support for reasonably determining the disturbance instability criterion of joints. 展开更多
关键词 coupled static-dynamic loading instability energy irreversible displacement JOINTS stability
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Dynamic strength of rocks and physical nature of rock strength 被引量:5
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作者 Qihu Qian Chengzhi Qi mingyang wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE 2009年第1期1-10,共10页
Time-dependence of rock deformation and fracturing is often ignored.However,the consideration of the time-dependence is essential to the study of the deformation and fracturing processes of materials,especially for th... Time-dependence of rock deformation and fracturing is often ignored.However,the consideration of the time-dependence is essential to the study of the deformation and fracturing processes of materials,especially for those subject to strong dynamic loadings.In this paper,we investigate the deformation and fracturing of rocks,its physical origin at the microscopic scale,as well as the mechanisms of the time-dependence of rock strength.Using the thermo-activated and macro-viscous mechanisms,we explained the sensitivity of rock strength to strain rate.These mechanisms dominate the rock strength in different ranges of strain rates.It is also shown that a strain-rate dependent Mohr-Coulomb-type constitutive relationship can be used to describe the influence of strain rate on dynamic rock fragmentation.A relationship between the particle sizes of fractured rocks and the strain rate is also proposed.Several time-dependent fracture criteria are discussed,and their intrinsic relations are discussed.Finally,the application of dynamic strength theories is discussed. 展开更多
关键词 岩石物理性质 动强度 应变率敏感性 时间依赖性 岩石变形 岩石强度 应变率相关 微观尺度
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Failure behavior of highly stressed rocks under quasi-static and intensive unloading conditions 被引量:3
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作者 Jie Li Pengxian Fan mingyang wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2013年第4期287-293,共7页
Unloading failure of rocks,especially highly stressed rocks,is one of the key issues in construction of underground structures.Based on this,analytical models for rocks under quasi-static and intensive unloading condi... Unloading failure of rocks,especially highly stressed rocks,is one of the key issues in construction of underground structures.Based on this,analytical models for rocks under quasi-static and intensive unloading conditions are established to study the failure behavior of highly stressed rocks.In case of rock failure under quasi-static unloading,the rock mass ahead of working face is regarded as an elasto-brittle material,and the stress-displacement curves are used to characterize the tensile fracture of peak-stress area.It is observed that,when intensive unloading happens,there is an elastic unloading wave(perturbation wave) propagating in the rock mass.If the initial stress exceeds the critical stress,there will be a fracture wave,following the elastic unloading wave.To study the propagation feature of fracture wave,the conservation laws of mass,momentum and energy are employed.Results show that the post-peak deformation,strength and energy dissipation are essential to the failure process of highly stressed rocks. 展开更多
关键词 卸载条件 破坏行为 准静态 集约化 岩石 能量守恒定律 拉伸断裂 传播特性
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Establishment of an Objective Standard for the Definition of Binary Tropical Cyclones in the Western North Pacific 被引量:3
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作者 Fumin REN Yanjun XIE +2 位作者 Biwen YIN mingyang wang Guoping LI 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2020年第11期1211-1221,共11页
To develop an objective standard for defining binary tropical cyclones(BTCs)in the western North Pacific(WNP),two best-track datasets,from the China Meteorological Administration and the Joint Typhoon Warning Center,w... To develop an objective standard for defining binary tropical cyclones(BTCs)in the western North Pacific(WNP),two best-track datasets,from the China Meteorological Administration and the Joint Typhoon Warning Center,were adopted for statistical analyses on two important characteristics of BTCs-two TCs approaching each other,and counterclockwise spinning.Based on the high consistency between the two datasets,we established an objective standard,which includes a main standard for defining BTCs and a secondary standard for identifying typical/atypical BTCs.The main standard includes two requirements:two coexisting TCs are a pair of BTCs if(i)the separation distance is≤1800 km,and(ii)this separation maintains for at least 12 h.Meanwhile,the secondary standard defines a typical BTC as one for which there is at least one observation when the two TCs approach each other and spin counterclockwise simultaneously.Under the standard,the ratio of typical BTCs increases as the BTC duration increases or the minimum distance between the two TCs decreases.Then,using the JTWC dataset,it was found that there are 505 pairs of BTCs during the period 1951−2014,including 328 typical BTCs and 177 atypical BTCs,accounting for 65.0%and 35.0%of the total,respectively.In addition,a study of two extreme phenomena-the maximum approaching speed and the maximum counterclockwise angular velocity in typical BTCs-shows that the configuration of the circulation conditions and the distribution of the BTCs favor the formation of these extreme phenomena. 展开更多
关键词 objective standard binary tropical cyclones Western North Pacific
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Time-dependent dilatancy for brittle rocks 被引量:1
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作者 Jie Li mingyang wang +2 位作者 Kaiwen Xia Ning Zhang Houxu Huang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2017年第6期1054-1070,共17页
This paper presents a theoretical study on time-dependent dilatancy behaviors for brittle rocks. The theory employs a well-accepted postulation that macroscopically observed dilatancy originates from the expansion of ... This paper presents a theoretical study on time-dependent dilatancy behaviors for brittle rocks. The theory employs a well-accepted postulation that macroscopically observed dilatancy originates from the expansion of microcracks. The mechanism and dynamic process that microcracks initiate from local stress concentration and grow due to localized tensile stress are analyzed. Then, by generalizing the results from the analysis of single cracks, a parameter and associated equations for its evolution are developed to describe the behaviors of the microcracks. In this circumstance, the relationship between microcracking and dilatancy can be established, and the theoretical equations for characterizing the process of rock dilatancy behaviors are derived. Triaxial compression and creep tests are conducted to validate the developed theory. With properly chosen model parameters, the theory yields a satisfactory accuracy in comparison with the experimental results. 展开更多
关键词 TIME-DEPENDENT DILATANCY Microcracking SUBCRITICAL CRACK growth ROCK DEFORMATION and failure
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A laboratory method to simulate seismic waves induced by underground explosions
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作者 Yuguo Ji mingyang wang +4 位作者 Jie Li Shuxin Deng Zhihao Li Tianhan Xu Fei Gao 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2022年第5期1514-1530,共17页
The seismic waves induced by underground explosions generate geological hazards affecting deep buried tunnels such as rockbursts and engineering-induced earthquakes. This issue is difficult to study through full-scale... The seismic waves induced by underground explosions generate geological hazards affecting deep buried tunnels such as rockbursts and engineering-induced earthquakes. This issue is difficult to study through full-scale testing due to the expense and unpredictable danger. To solve this problem, the authors developed experimental apparatus and presented a laboratory method to simulate seismic waves induced by underground explosions. In this apparatus, a combined structure of a diffusive-shaped water capsule and a special-shaped oil capsule was designed. This structure can provide an applied confining stress and freely transmit the stress wave generated by external impact. Therefore, the coupled loading of in situ stress and seismic waves induced by underground explosions in the deep rock mass was simulated. The positive pressure time and peak value of the stress wave could be adjusted by changing the pulse-shaper and the initial impact energy. The obtained stress waves in the experiments correspond to that generated by 0.15-120 kt of TNT equivalent explosion at a scaled distance of 89.9-207.44 m/kt. 展开更多
关键词 Laboratory method Seismic wave Underground explosion Deep rock mass Coupled loading Experimental apparatus
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Design of functionalized fluorescent ionic liquid and its application for achieving significant improvements in Al^3t detecting
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作者 Lu Gan Jiachen Guo +4 位作者 Siying Che Qiaoxin Xiao mingyang wang Jienan You Congmin wang 《Green Energy & Environment》 SCIE CSCD 2020年第2期195-202,共8页
Specific fluorophore was introduced into ionic liquid based on its tunability,thus a kind of novel fluorescent ionic liquid probe[P66614][HQS]was designed,synthesized and characterized.Compared with non-fluorescent HQ... Specific fluorophore was introduced into ionic liquid based on its tunability,thus a kind of novel fluorescent ionic liquid probe[P66614][HQS]was designed,synthesized and characterized.Compared with non-fluorescent HQS,ionic liquid[P66614][HQS]emitted a certain amount of fluorescence,which could be attributed to the well-delocalized frontier orbitals and its charge transfer character,as demonstrated by quantum chemical calculation.Considering the interaction of[P66614][HQS]with metal ions,the application for detecting specific substance as a chemical sensor,such as Al3+was investigated.Compared with the traditional probe HQS,significant improvements in Al^3+detecting was achieved by[P66614][HQS]with stronger binding ability,better sensitivity and selectivity.The better performance of[P66614][HQS]was contributed to the changed charge distribution,leading to the stronger binding interaction.We believe that this new fluorescent ionic liquid exhibited unique properties in detecting Al^3+in aqueous solution,which would broaden the application of ionic liquids. 展开更多
关键词 Ionic liquid Fluorescent probe AL^3+ Significant improvements
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Meteorological Data Generation for the Numerical Simulation of Stratified Flow in the Joumine Reservoir, Tunisia
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作者 Tadaharu Ishikawa Kakeru Takahira +1 位作者 mingyang wang Mitsuteru Irie 《Journal of Environmental Science and Engineering(B)》 2014年第4期173-180,共8页
关键词 动态数值模拟 数据生成 气象站 突尼斯 水库 分层流 时间序列数据 二阶微分方程
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Study on surface discharge of nonlinear conductive epoxy resin/SrTiO3 composites in 80–300 K temperature zone
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作者 Yunqi Xing Bin wang +3 位作者 mingyang wang Jiakai Chi Peng Jia Rongjin Huang 《High Voltage》 SCIE EI CSCD 2024年第1期117-126,共10页
Bisphenol F epoxy resin(EP)is often used in terminal current lead insulation of superconducting equipment because of its good insulation performance,high mechanical strength,good toughness at cryogenic temperatures,an... Bisphenol F epoxy resin(EP)is often used in terminal current lead insulation of superconducting equipment because of its good insulation performance,high mechanical strength,good toughness at cryogenic temperatures,and resistance to cold shock and heat shock.However,due to the wide temperature range of 80–300 K and the strong electric field,the EP-N_(2)interface is prone to surface flashover,resulting in terminal insulation failure.To improve the reliability of the current lead insulation,non-linear conductive EP/strontium titanate(SrTiO_(3))composites were prepared by modification with nano filling.The changes of dielectric,surface discharge,flashover,and trap distribution characteristics of composite materials were studied,and the mechanism of SrTiO_(3)on the surface flashover of composite materials was analysed.The results show that the conductivity of the composite increases with the rise of SrTiO_(3)filling content,and the amplitude of improvement is greater under the strong electric field,showing a more significant non-linearity.The composite has a lower trap energy level and a greater number of shallow traps compared to pure EP,which accelerates surface charge detrapping and reduces charge accumulation,effectively enhancing the discharge and surface flashover voltage of the composite. 展开更多
关键词 COMPOSITES COMPOSITE INSULATION
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基于深度学习的全新药物设计研究进展 被引量:3
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作者 王明阳 李丹 +1 位作者 侯廷军 康玉 《中国科学:化学》 CAS CSCD 北大核心 2023年第1期95-106,共12页
先导化合物的设计和发现是新药研发中最具挑战性和创造性的阶段,其过程需考虑候选分子的结构新颖性、生物活性、靶标选择性、可合成性、成药性和安全性等多种属性的优化.虽然计算机辅助药物设计方法的发展和应用大大节省了先导化合物发... 先导化合物的设计和发现是新药研发中最具挑战性和创造性的阶段,其过程需考虑候选分子的结构新颖性、生物活性、靶标选择性、可合成性、成药性和安全性等多种属性的优化.虽然计算机辅助药物设计方法的发展和应用大大节省了先导化合物发现阶段的时间和经济成本,但仍未能扭转新药研发成功率低的现状.近年来,随着深度学习技术的不断发展,基于深度学习的全新药物设计方法为先导化合物的发现带来新的契机,前景巨大.这些全新药物设计模型使用的深度学习框架包括编码-解码器、循环神经网络、生成对抗网络、强化学习等.本文综述了这些深度学习框架的基本原理、模型输入分子表征以及效果评测指标,并对其在全新药物设计领域的应用前景进行了展望. 展开更多
关键词 全新药物设计 计算机辅助药物设计 深度学习 机器学习 分子生成
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Scale-space effect and scale hybridization in image intelligent recognition of geological discontinuities on rock slopes
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作者 mingyang wang Enzhi wang +1 位作者 Xiaoli Liu Congcong wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE 2024年第4期1315-1336,共22页
Geological discontinuity(GD)plays a pivotal role in determining the catastrophic mechanical failure of jointed rock masses.Accurate and efficient acquisition of GD networks is essential for characterizing and understa... Geological discontinuity(GD)plays a pivotal role in determining the catastrophic mechanical failure of jointed rock masses.Accurate and efficient acquisition of GD networks is essential for characterizing and understanding the progressive damage mechanisms of slopes based on monitoring image data.Inspired by recent advances in computer vision,deep learning(DL)models have been widely utilized for image-based fracture identification.The multi-scale characteristics,image resolution and annotation quality of images will cause a scale-space effect(SSE)that makes features indistinguishable from noise,directly affecting the accuracy.However,this effect has not received adequate attention.Herein,we try to address this gap by collecting slope images at various proportional scales and constructing multi-scale datasets using image processing techniques.Next,we quantify the intensity of feature signals using metrics such as peak signal-to-noise ratio(PSNR)and structural similarity(SSIM).Combining these metrics with the scale-space theory,we investigate the influence of the SSE on the differentiation of multi-scale features and the accuracy of recognition.It is found that augmenting the image's detail capacity does not always yield benefits for vision-based recognition models.In light of these observations,we propose a scale hybridization approach based on the diffusion mechanism of scale-space representation.The results show that scale hybridization strengthens the tolerance of multi-scale feature recognition under complex environmental noise interference and significantly enhances the recognition accuracy of GD.It also facilitates the objective understanding,description and analysis of the rock behavior and stability of slopes from the perspective of image data. 展开更多
关键词 Image processing Geological discontinuities Deep learning Multi-scale Scale-space theory Scale hybridization
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Effects of surface roughness on the aerodynamic performance of a high subsonic compressor airfoil at low Reynolds number 被引量:2
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作者 mingyang wang Chengwu YANG +3 位作者 Ziliang LI Shengfeng ZHAO Yanfeng ZHANG Xin’gen LU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2021年第3期71-81,共11页
The aerodynamic performance of compressor airfoil is significantly affected by the surface roughness at low Reynolds number(Re).In the present study,numerical simulations have been conducted to investigate the impact ... The aerodynamic performance of compressor airfoil is significantly affected by the surface roughness at low Reynolds number(Re).In the present study,numerical simulations have been conducted to investigate the impact of surface roughness on the profile loss of a high subsonic compressor airfoil at Re=1.5×10^(5).Four roughness locations,covering 10%,30%,50%and 100%of the suction surface from the leading edge and seven roughness magnitudes(Ra)ranging from 52 to525 lm were selected.Results showed that the surface roughness mainly determined the loss generation process by influencing the structure of the Laminar Separation Bubble(LSB)and the turbulence level near the wall.For all the roughness locations,the variation trend for the profile loss with the roughness magnitude was similar.In the transitionally rough region,the negative displacement effect of the LSB was suppressed with the increase of roughness magnitude,leading to a maximum decrease of 14.6%,16.04%,16.45%and 10.20%in the profile loss at Ra=157 lm for the four roughness locations,respectively.However,with a further increase of the roughness magnitude in the fully rough region,the stronger turbulent dissipation enhanced the growth rate of the turbulent boundary layer and increased the profile loss instead.By comparison,the leading edge roughness played a dominant role in the boundary layer development and performance variation.To take fully advantage of the surface roughness reducing profile loss at low Re,the effects of roughness on suppressing LSB and inducing strong turbulent dissipation should be balanced effectively. 展开更多
关键词 Aerodynamic performance Compressor airfoil Low Reynolds number Separation bubble Surface roughness Viscous dissipation
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Estimation of the desorption energy of dichloromethane and water in MIL-53 by DSC and ab-initio calculations 被引量:1
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作者 mingyang wang Xinghua Zhang +1 位作者 Yunlin Chen Ao Zhang 《Science China Chemistry》 SCIE EI CAS CSCD 2016年第4期398-404,共7页
Desorption energies of dichloromethane(CH_2Cl_2) and water(H_2O) in a metal-organic framework, MIL-53(Al), were investigated by the combination of experimental(differential scanning calorimeter, DSC) and computational... Desorption energies of dichloromethane(CH_2Cl_2) and water(H_2O) in a metal-organic framework, MIL-53(Al), were investigated by the combination of experimental(differential scanning calorimeter, DSC) and computational(ab-initio calculations) methods. The differences of desorption energy and natural log of the frequency factor of CH_2Cl_2 and H_2O in MIL-53(Al) were analyzed by a thermo active process using DSC measurements. The interaction energy of guest molecules with MIL-53(Al), which corresponds to the desorption in the thermal active process, was explored using ab-initio calculation. As a result of the difference in the interaction energies of H_2O and CH_2Cl_2 in MIL-53(Al), the site near the μ_2-OH groups has two potential wells. Both experimentally and computationally, MIL-53 presents the preferential adsorption of CH_2Cl_2 than H_2O. 展开更多
关键词 从头计算 二氯甲烷 DSC 能量估计 解吸 CH2CL2 差示扫描量热仪 差示扫描量热法
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Risk factors associated with hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation 被引量:2
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作者 Biao Shen Yueshen Ma +15 位作者 Haixiao Zhang mingyang wang Jia Liu Jiaxin Cao Wenwen Guo Dan Feng Donglin Yang Rongli Zhang Xin Chen Qiaoling Ma Weihua Zhai Sizhou Feng Mingzhe Han Aiming Pang Erlie Jiang 《Blood Science》 2022年第2期83-88,共6页
Hemorrhagic cystitis(HC)is a common complication of allogeneic hematopoietic stem cell transplantation(HSCT).The incidence is about 7%to 68%,and some patients have to suffer a long period of frequent,urgent,and painfu... Hemorrhagic cystitis(HC)is a common complication of allogeneic hematopoietic stem cell transplantation(HSCT).The incidence is about 7%to 68%,and some patients have to suffer a long period of frequent,urgent,and painful urination,which brings great pain.This study aimed to analyze risk factors of HC and its effect on patient survival.We collected the medical records of 859 patients who underwent HSCT at our hospital between August 2016 and August 2020.Patients with and without HC were matched using propensity score matching at a 1:1 ratio based on sex,age,and diagnosis,and logistic regression analyses were used to identify factors associated with HC.We used Kaplan–Meier curves to analyze the survival rates of patients in the HC and non-HC groups.We also analyzed the relationship between BK viral load and the occurrence of HC using receiver operating characteristic curve(ROC)analysis.After propensity score matching,there were 131 patients each in the HC and non-HC groups.In the HC group,89 patients(67.9%)had mild HC(stage II°)and 43(32.1%)had severe HC(stage III–IV).The median interval between stem cell transplantation and HC development was 31(3–244)days.Univariate analysis indicated that donor age,hematopoietic stem cell source,HLA,acute graft-versus-host disease,busulfan,anti-thymocyte globulin(ATG),total body irradiation,cytomegalovirus(CMV)(urine),and BK polyomavirus(BKV)(urine)were significantly associated with HC.ATG,CMV(urine),and BKV(urine)were independent risk factors for HC based on the multivariate analysis.The Kaplan–Meier survival analysis showed no significant difference between the HC and non-HC groups(P=0.14).The 1-and 2-year survival rates in the HC group were 78.4%and 69.6%,respectively,and the corresponding rates in the non-HC group were 84.4%and 80.7%,respectively.ROC analysis indicated that a urine BKV load of 1×10^(7) copies/mL was able to stratify the risk of HC.In conclusion,when the BKV load is>1×10^(7),we needtobe aware of the potential for the development of HC. 展开更多
关键词 Allogeneic hematopoietic stem cell transplantation Hemorrhagic cystitis PROGNOSIS Risk factors
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Vortex dynamics and entropy generation in separated transitional flow over a compressor blade at various incidence angles 被引量:1
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作者 mingyang wang Ziliang LI +4 位作者 Ge HAN Chengwu YANG Shengfeng ZHAO Yanfeng ZHANG Xin’gen LU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2022年第3期42-52,共11页
The transition process within a Laminar Separation Bubble(LSB)that formed on a compressor blade surface was investigated using Large Eddy Simulations(LESs)at a Reynolds number of 1.5×10;and incidence angles of 0&... The transition process within a Laminar Separation Bubble(LSB)that formed on a compressor blade surface was investigated using Large Eddy Simulations(LESs)at a Reynolds number of 1.5×10;and incidence angles of 0°,+3°,and+5°.The vortex dynamics in the separated shear layers were compared at various incidence angles and its effects on the loss generation were clarified through entropy analysis.Results showed that transition onset,which was accurately identified by the Linear Stability Theory(LST),was significantly promoted at the increased incidence angle.As such,the development of LSB was suppressed and the relative role of viscous instability played in the transition process was weakened.At the incidence angle of 0°,two-dimensional spanwise vortices detached from the blade surface and roiled up periodically,which were further stretched and eventually evolved into large-scale hairpin vortices.As time passed,the fully developed hairpin vortices broke down into small-scale eddies.Meanwhile,the flow near the wall reversely ejected into the outer separated shear layers and a sweeping process happened subsequently,forcing the separated shear layers to reattach and accelerating the generation of turbulent fluctuations.By comparison,the strength of vortex rolling-up was weakened at higher incidence angles,and the vortex pairing and breakdown of large-scale vortices were less pronounced.Therefore,the level of turbulent fluctuations that generated in the separated shear layers was reduced.Detailed entropy analysis showed that the turbulent dissipation effect related to the Reynolds shear stresses determined the largest amount of positive entropy generation,which declined to a lower level as the incidence angle increased from 0°to+5°.Correspondingly,the profile loss was reduced by 50.4%. 展开更多
关键词 Aerodynamic performance Compressor airfoil ENTROPY Incidence angle Separation bubble Vortex dynamics
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Investigation of Anticorrosive Performance of Oil-infused Slippery and Superhydrophobic Brass Surfaces by Laser Texturing 被引量:1
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作者 Li Zhang Chong Zhang +2 位作者 Jingrong Tang Bo Hao mingyang wang 《Journal of Bionic Engineering》 SCIE EI CSCD 2021年第5期1157-1167,共11页
Brass is widely used in machinery,electronic appliances and emerging industries.The corrosion resistance of laser-induced superhydrophobic surface of brass needs to be improved.In recent years,bionic surface with slip... Brass is widely used in machinery,electronic appliances and emerging industries.The corrosion resistance of laser-induced superhydrophobic surface of brass needs to be improved.In recent years,bionic surface with slippery coating has attracted much attention because of its excellent corrosion inhibition performance.Here,we first prepared the superhydrophobic surface of brass by nanosecond laser ablation combined with fluoroalkyl silane modification,and then injected silicone oil into the prepared superhydrophobic matrix to obtain a slippery coating surface.PDP and EIS tests in 3.5 wt.%NaCl solution showed that the corrosion resistance of the slippery surface was better than that of the superhydrophobic surface.This study can play a certain role in promoting the development of metal anticorrosive coating and is of great significance in the preparation of slippery surface by laser induction,and provides a convenient and eff ective means for metal anticorrosion in the industrial field. 展开更多
关键词 Nanosecond laser SUPERHYDROPHOBIC Slippery surface Corrosion resistance
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Experimental investigation on dynamic mechanical properties of sandy clay treated with alkali-activated metakaolin cement and discrete polypropylene fibers
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作者 Ruiqiu Ma mingyang wang +1 位作者 Xinping Li Tingting Liu 《Underground Space》 SCIE EI 2022年第6期1036-1055,共20页
The dynamic mechanical properties and dynamic energy absorption capacity of marine sandy clay,which was stabilized by cement with partial substitution of alkali-activated metakaolin(AAMK)and discrete polypropylene fib... The dynamic mechanical properties and dynamic energy absorption capacity of marine sandy clay,which was stabilized by cement with partial substitution of alkali-activated metakaolin(AAMK)and discrete polypropylene fibers,were experimentally investigated at strain rates of 80-280 s^(-1).The AAMK,as partial replacement of cement,is eco-friendly and economical,and polypropylene fibers with corrosion resistance can withstand severe environmental conditions.Dynamic mechanical properties of 16 different mix ratios were experimentally examined via split Hopkinson compression pressure bar(SHPB)tests.Typical macroscopic post-impact fragment patterns Ⅰ and Ⅱ were observed in dynamic stress-strain curves and macroscopic fragmentations.The results confirmed an obvious enhancement in the dynamic compressive strength and energy absorption density due to the use of cement with partial substitution of AAMK and the addition of polypropylene fibers and sand.Based on scanning electron microscopy(SEM)tests and nuclear magnetic resonance(NMR)tests,cemented sandy clay specimens treated with 0.2%fiber contents or higher exhibited a denser network of soil particles with hydration products.The connection mechanism and typical interface between fiber-sand-hydrate-sandy clay particles were observed via SEM tests.Furthermore,an optimal mix ratio was proposed to satisfy the demands of high dynamic mechanical properties,energy absorption capacity,and economic and environmental constraints.The optimal mix ratio corresponded to 0.2% fiber content or higher and sand content of up to 16%.Additionally,it was observed that the dynamic compressive strength of samples with 0.1% fibers or less deteriorated.Based on absorption energy density and failure modes analysis,the fiber content should be higher than or equal to 0.2% to effectively reduce the degree of fragmentation and increase the size of fragments. 展开更多
关键词 Cemented sandy clay Split Hopkinson pressure bar Dynamic compressive strength Energy absorption Microstructure NMR
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