<i><span style="font-family:Verdana;">Helicobacter pylori</span></i><span style="font-family:Verdana;"> infection is a major public health problem globally, with high ...<i><span style="font-family:Verdana;">Helicobacter pylori</span></i><span style="font-family:Verdana;"> infection is a major public health problem globally, with high prevalence in developing countries associated with poor sanitation, low standard of living, urban-rural disparity and increased gastrointestinal pathologies. This preliminary study determine</span><span style="font-family:Verdana;">d</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> the seroprevalence of </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:;" "=""><span style="font-family:Verdana;"> infection among asymptomatic rural population and association of sociodemographic variables on the result outcome. A total of 250 asymptomatic volunteered participants were screened for </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:Verdana;"> antibodies, using rapid immunochromatographic strips. 44.8%</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(112/250) were seropositive, and showed increased prevalence with the age</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">group, <15</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years (8.0%), 18</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">39</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(23.5%) and 40</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">65</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(12</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">0%) with no significant difference. High prevalence among males,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">88</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(35.2) compared to 24</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(9.6) females</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.228). Significant association was observed with marital status, high prevalence among married participants 63</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(25.0) followed by singles,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">41</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(16.4)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.010). Similarly, significant prevalence </span><span style="font-family:Verdana;">was </span><span style="font-family:Verdana;">observed among participants with non-formal education,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">60</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(24.0) followed by primary education,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">21</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(8.4)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.51).</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">While non-salary earners accounted for 79</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(31.6)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">0.244). The </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><i><span style="font-family:;" "=""> </span></i><span style="font-family:;" "=""><span style="font-family:Verdana;">seropositivity of 44.8% is relatively low in region with previous reports of high prevalence and predisposing risk factors. Further studies are needed to evaluate the effect of environmental and occupational risk factors for better epidemiological understanding of </span><i><span style="font-family:Verdana;">H. pylori</span></i><span style="font-family:Verdana;"> infection and a template for intervention measures.</span></span>展开更多
<b><span style="font-family:Verdana;">Introduction</span><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> Haema...<b><span style="font-family:Verdana;">Introduction</span><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> Haematological profile of pregnant women provides vital information on physiological changes in pregnancy progress, outcome and possible maternal-foetal complications. The study assessed the haematological profile of pregnant women attending the antenatal clinic</span><span style="font-family:Verdana;">. </span><b><span style="font-family:Verdana;">Methodology</span><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> The cross-sectional study was conducted at the antenatal clinic of Abubakar Tafawa Balewa Teaching Hospital, Bauchi between July and September 2018 among pregnant women attending the antenatal clinic. Study participant w</span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> recruited on voluntary basis and study questionnaire and informed consent administered. Blood samples </span><span style="font-family:Verdana;">are </span><span style="font-family:Verdana;">collected and analysed using System</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">x haematology autoanalyser.</span><span style="font-size:10pt;font-family:""> </span><b><span style="font-family:Verdana;">Result</span><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> A total of 191 study participants comprised</span><span style="font-family:Verdana;"> of</span><span style="font-family:Verdana;"> 141 pregnant women at different trimester stages and 50 non-pregnant. Mean haematocrit, haemgloblin, white blood count and platelet count of 35.8</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">±</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">9.0, 11.6</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">±</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">1.6, 7.7</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">±</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">5.7, and 234.0</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">±</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">74.6 respectively.</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">Significant difference was observed between pregnant and non-pregnant women in neutrophil (0.016), mixed (eosinophil, basophil and monocyte, 0.05), lymphocyte (0.000), platelets (0.002) and RDWSD (0.025).</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">Comparing haematological profile with trimester stages, significant association was observed with white blood cells count and mixed cell counts.</span><span style="font-size:10pt;font-family:""> </span><b><span style="font-family:Verdana;">Conclusion</span><span style="font-family:Verdana;">: </span></b><span style="font-family:Verdana;">The</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">reduction in mean white blood cells count and increased haemocrit</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">concentration with the trimester stages contradict patterns in other</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">similar studies. This further highlights the need for local data for early diagnosis of pregnancy-associated clinical conditions and management approach.展开更多
文摘<i><span style="font-family:Verdana;">Helicobacter pylori</span></i><span style="font-family:Verdana;"> infection is a major public health problem globally, with high prevalence in developing countries associated with poor sanitation, low standard of living, urban-rural disparity and increased gastrointestinal pathologies. This preliminary study determine</span><span style="font-family:Verdana;">d</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> the seroprevalence of </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:;" "=""><span style="font-family:Verdana;"> infection among asymptomatic rural population and association of sociodemographic variables on the result outcome. A total of 250 asymptomatic volunteered participants were screened for </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><span style="font-family:Verdana;"> antibodies, using rapid immunochromatographic strips. 44.8%</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(112/250) were seropositive, and showed increased prevalence with the age</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">group, <15</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years (8.0%), 18</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">39</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(23.5%) and 40</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">65</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">years</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(12</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">0%) with no significant difference. High prevalence among males,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">88</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(35.2) compared to 24</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(9.6) females</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.228). Significant association was observed with marital status, high prevalence among married participants 63</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(25.0) followed by singles,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">41</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(16.4)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.010). Similarly, significant prevalence </span><span style="font-family:Verdana;">was </span><span style="font-family:Verdana;">observed among participants with non-formal education,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">60</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(24.0) followed by primary education,</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">21</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(8.4)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.51).</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">While non-salary earners accounted for 79</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(31.6)</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(p</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">0.244). The </span><i><span style="font-family:Verdana;">H.</span></i></span><i><span style="font-family:;" "=""> </span></i><i><span style="font-family:Verdana;">pylori</span></i><i><span style="font-family:;" "=""> </span></i><span style="font-family:;" "=""><span style="font-family:Verdana;">seropositivity of 44.8% is relatively low in region with previous reports of high prevalence and predisposing risk factors. Further studies are needed to evaluate the effect of environmental and occupational risk factors for better epidemiological understanding of </span><i><span style="font-family:Verdana;">H. pylori</span></i><span style="font-family:Verdana;"> infection and a template for intervention measures.</span></span>
文摘<b><span style="font-family:Verdana;">Introduction</span><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> Haematological profile of pregnant women provides vital information on physiological changes in pregnancy progress, outcome and possible maternal-foetal complications. The study assessed the haematological profile of pregnant women attending the antenatal clinic</span><span style="font-family:Verdana;">. </span><b><span style="font-family:Verdana;">Methodology</span><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> The cross-sectional study was conducted at the antenatal clinic of Abubakar Tafawa Balewa Teaching Hospital, Bauchi between July and September 2018 among pregnant women attending the antenatal clinic. Study participant w</span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> recruited on voluntary basis and study questionnaire and informed consent administered. Blood samples </span><span style="font-family:Verdana;">are </span><span style="font-family:Verdana;">collected and analysed using System</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">x haematology autoanalyser.</span><span style="font-size:10pt;font-family:""> </span><b><span style="font-family:Verdana;">Result</span><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> A total of 191 study participants comprised</span><span style="font-family:Verdana;"> of</span><span style="font-family:Verdana;"> 141 pregnant women at different trimester stages and 50 non-pregnant. Mean haematocrit, haemgloblin, white blood count and platelet count of 35.8</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">±</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">9.0, 11.6</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">±</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">1.6, 7.7</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">±</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">5.7, and 234.0</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">±</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">74.6 respectively.</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">Significant difference was observed between pregnant and non-pregnant women in neutrophil (0.016), mixed (eosinophil, basophil and monocyte, 0.05), lymphocyte (0.000), platelets (0.002) and RDWSD (0.025).</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">Comparing haematological profile with trimester stages, significant association was observed with white blood cells count and mixed cell counts.</span><span style="font-size:10pt;font-family:""> </span><b><span style="font-family:Verdana;">Conclusion</span><span style="font-family:Verdana;">: </span></b><span style="font-family:Verdana;">The</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">reduction in mean white blood cells count and increased haemocrit</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">concentration with the trimester stages contradict patterns in other</span><span style="font-size:10pt;font-family:""> </span><span style="font-family:Verdana;">similar studies. This further highlights the need for local data for early diagnosis of pregnancy-associated clinical conditions and management approach.
