The sickle cell disease sickle cell anemia called Expired aussi is a genetic disease Caused by abnormal hemoglobin. The pediatric ward of the provincial hospital kenitra recorded a workforce of 164 children with sickl...The sickle cell disease sickle cell anemia called Expired aussi is a genetic disease Caused by abnormal hemoglobin. The pediatric ward of the provincial hospital kenitra recorded a workforce of 164 children with sickle cell disease over a period of twenty four months (June 2010-June 2012). On average seven to eight (7 to 8) children are born per year with this disease. The majority of these children are admitted to the pediatric ward and have an increased susceptibility to infections. To identify socio-economic and environmental factors in the care of children and their families. The study group consists of 60 children aged 7 - 14 years. Clinical and analytical information is obtained from records and doctors during consultations of these patients. The results show that 64% of these children are from rural areas against 30% of children of urban origin, while 6% live in suburban areas, however 68% of these children use septic false. In parallel they consume well water. Clinical examination and white blood cell count revealed a prevalence of 76% for fever cases reviews some of qui-have ticemia September, 43% for leukocytosis. Moreover, we noted that diarrhea is very common in this sample. Parenting was made bacteriological examinations of well water consumed by these children. In conclusion, the present study showed a significant combination entre les frequency of sickle cell crises infectious presented by the children studied and the environmental quality of life and family in the child qui develops.展开更多
Sickle cell anemia is an autosomal recessive genetic disease by mutation of the β globin gene. This mutation induces the synthesis of abnormal hemoglobin (Hb) HbS, Mainly responsible for all clinical manifestations v...Sickle cell anemia is an autosomal recessive genetic disease by mutation of the β globin gene. This mutation induces the synthesis of abnormal hemoglobin (Hb) HbS, Mainly responsible for all clinical manifestations vaso-occlusives and chronic hemolysis with variable anemia. The objective of this study is the determination profile of haematological parameters of sickle cell children of the province of Kenitra (Morocco). In order to know the usual values and the particularities which are its own, we have observed that 50% of sickle cell children in our case study have severe anemia and 84% in patients aged 5 to 11 years. In addition, there is no significant difference among gender. The cases of hemoglobinosis S are divided into: Homozygous hemoglobinosis S (43%), Heterozygous sickle cell disease (17%), Hemoglobinosis S associated with alpha-thalassemia (1%), Hemoglobinosis S composite heterozygosity S/beta-thalassemia (5%), S/PHHF composite heterozygosity (6%), eventually composite heterozygosity S/beta+ thalassemia (28%). Homozygous sickle cell children have a long hospital stay, the highest number of hospitalizations and very severe sickle cell syndromes compared to the other phenotypic status of our population.展开更多
文摘The sickle cell disease sickle cell anemia called Expired aussi is a genetic disease Caused by abnormal hemoglobin. The pediatric ward of the provincial hospital kenitra recorded a workforce of 164 children with sickle cell disease over a period of twenty four months (June 2010-June 2012). On average seven to eight (7 to 8) children are born per year with this disease. The majority of these children are admitted to the pediatric ward and have an increased susceptibility to infections. To identify socio-economic and environmental factors in the care of children and their families. The study group consists of 60 children aged 7 - 14 years. Clinical and analytical information is obtained from records and doctors during consultations of these patients. The results show that 64% of these children are from rural areas against 30% of children of urban origin, while 6% live in suburban areas, however 68% of these children use septic false. In parallel they consume well water. Clinical examination and white blood cell count revealed a prevalence of 76% for fever cases reviews some of qui-have ticemia September, 43% for leukocytosis. Moreover, we noted that diarrhea is very common in this sample. Parenting was made bacteriological examinations of well water consumed by these children. In conclusion, the present study showed a significant combination entre les frequency of sickle cell crises infectious presented by the children studied and the environmental quality of life and family in the child qui develops.
文摘Sickle cell anemia is an autosomal recessive genetic disease by mutation of the β globin gene. This mutation induces the synthesis of abnormal hemoglobin (Hb) HbS, Mainly responsible for all clinical manifestations vaso-occlusives and chronic hemolysis with variable anemia. The objective of this study is the determination profile of haematological parameters of sickle cell children of the province of Kenitra (Morocco). In order to know the usual values and the particularities which are its own, we have observed that 50% of sickle cell children in our case study have severe anemia and 84% in patients aged 5 to 11 years. In addition, there is no significant difference among gender. The cases of hemoglobinosis S are divided into: Homozygous hemoglobinosis S (43%), Heterozygous sickle cell disease (17%), Hemoglobinosis S associated with alpha-thalassemia (1%), Hemoglobinosis S composite heterozygosity S/beta-thalassemia (5%), S/PHHF composite heterozygosity (6%), eventually composite heterozygosity S/beta+ thalassemia (28%). Homozygous sickle cell children have a long hospital stay, the highest number of hospitalizations and very severe sickle cell syndromes compared to the other phenotypic status of our population.
