Purpose: We evaluated biochemical analysis results with the aim of discovering serum levels that have possible effects on the development of retinopathy of prematurity (ROP). Methods: A retrospective study was conduct...Purpose: We evaluated biochemical analysis results with the aim of discovering serum levels that have possible effects on the development of retinopathy of prematurity (ROP). Methods: A retrospective study was conducted between January 2017 and January 2018 on a total of 110 infants with 35 or less gestational weeks. The sample included 78 infants who had been diagnosed with different stages of ROP and 32 infants without ROP. Results from routine serum biochemical analyses, performed at birth and at one month after birth, were evaluated. The Independent Sample t-test and Mann-Whitney U test were performed to compare the data. Results: The infants with ROP were born at a mean of 28.0 (±2.1) weeks of gestation, weighing a mean of 1066 (±314) g, and the mean duration of stay in the incubator was 38.2 (±19) days. The infants without ROP were born at a mean of 29.6 (±2.6) weeks of gestation, weighing a mean of 1265 (±372) g. 59 infants (53.6%) were females, and 51 (46.4%) were males. Between infants with and without ROP, differences in the following levels were not statistically significant: glucose, blood urine nitrogen, creatinine, alanine aminotransferase, aspartate aminotransferase, albumin, total protein, direct bilirubin, indirect bilirubin, uric acid, and phosphorus. Serum magnesium (Mg) levels at birth in infants with ROP were significantly higher than infants without ROP (p = 0.014). Conclusions: Serum Mg levels at birth were found to be higher in infants with ROP than in those without ROP. The levels may be dependent on the mothers’ treatment of Mg for different medical reasons.展开更多
Purpose: We aimed to evaluate 458 infants, who were followed up due to retinopathy of prematurity (ROP), demographically and epidemiologically. Methods: 458 infants with ROP, who were referred from our hospital’s neo...Purpose: We aimed to evaluate 458 infants, who were followed up due to retinopathy of prematurity (ROP), demographically and epidemiologically. Methods: 458 infants with ROP, who were referred from our hospital’s neonatal intensive care unit and from other health centers to our clinic for the staging and treatment between February 2016 and December 2017, were studied retrospectively. Design: Retrospective-observational study. Results: Of the 458 infants, 243 infants (53.06%) did not have ROP and they were at a mean of 32nd (26 - 35) gestational week, weighing a mean of 1700 (820 - 2830) gr. The remaining 215 (46.94%) infants were diagnosed with ROP at various stages and they were at a mean of 29th (23 - 35) gestational week, weighing a mean of 1180 (490 - 2850) gr. Of the infants without ROP, 116 (47.7%) were females and 127 (52.3%) were males. The mean duration of stay at the incubator was a mean of 16.5 (0 - 120) days and the mean duration of follow-up was a mean of 43 (40 - 56) weeks. 103 (40.2%) of them were breastfed only. Of the infants with ROP at various stages, 95 (44.2%) were females, and 120 (55.8%) were males. The mean duration of stay at the incubator was 42 (6 - 195) days, and the mean duration of follow-up was 48 (40 - 73) weeks. 43 (20.0%) of them were breastfed only. 32 (13.2%) infants without ROP were born of multi-fetal pregnancies. Only 1 of them was born as one of the triplets. Of the babies with ROP;56 (26.04%) were born of multi-fetal pregnancies, 5 of them being triplets. The numerical values of the gestational week at birth and the birth weight, and the rates of breastfeeding were lower in infants with ROP compared to the ones without it (p 0.05, Conclusions: This study showed that the gestational age, birth weight, breastfeeding rates, birth history and follow-up periods of multiple fetal pregnancies were different in ROP infants compared to non-ROP infants.展开更多
Purpose: Retinopathy of prematurity (ROP), an abnormal proliferation of retinal vessels in premature infants with low birth weight, develops due to many factors. This study investigated a possible correlation between ...Purpose: Retinopathy of prematurity (ROP), an abnormal proliferation of retinal vessels in premature infants with low birth weight, develops due to many factors. This study investigated a possible correlation between haematological parameters and ROP development. Method: This study included 189 infants without ROP and 128 with ROP. All were born at 35 weeks’ gestation or earlier, had a CBC drawn within 72 hours of birth, and had haemogram data for the first month. Haemoglobin (Hb), haematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), red cell distribution width (RDW), platelet counts (PLT), mean platelet volume (MPV) and platelet distribution width (PDW) values were obtained from hospital data and retrospectively analysed. Results: The mean gestational age was 31 weeks and 29 weeks for the control and ROP groups, respectively;the mean birth weights were 1757 g and 1332 g, respectively. The ROP group’s birth Hb, MCV and RDW were significantly lower than the control group (p p p p Conclusion: Premature infants with ROP had lower Hb and increased platelet, MPV and PDW in early postnatal life than infants without ROP. In the first month, when ROP develops, low PLT, PDW and Hb and high MPV could be indicators for ROP diagnosis, follow-up and treatment.展开更多
文摘Purpose: We evaluated biochemical analysis results with the aim of discovering serum levels that have possible effects on the development of retinopathy of prematurity (ROP). Methods: A retrospective study was conducted between January 2017 and January 2018 on a total of 110 infants with 35 or less gestational weeks. The sample included 78 infants who had been diagnosed with different stages of ROP and 32 infants without ROP. Results from routine serum biochemical analyses, performed at birth and at one month after birth, were evaluated. The Independent Sample t-test and Mann-Whitney U test were performed to compare the data. Results: The infants with ROP were born at a mean of 28.0 (±2.1) weeks of gestation, weighing a mean of 1066 (±314) g, and the mean duration of stay in the incubator was 38.2 (±19) days. The infants without ROP were born at a mean of 29.6 (±2.6) weeks of gestation, weighing a mean of 1265 (±372) g. 59 infants (53.6%) were females, and 51 (46.4%) were males. Between infants with and without ROP, differences in the following levels were not statistically significant: glucose, blood urine nitrogen, creatinine, alanine aminotransferase, aspartate aminotransferase, albumin, total protein, direct bilirubin, indirect bilirubin, uric acid, and phosphorus. Serum magnesium (Mg) levels at birth in infants with ROP were significantly higher than infants without ROP (p = 0.014). Conclusions: Serum Mg levels at birth were found to be higher in infants with ROP than in those without ROP. The levels may be dependent on the mothers’ treatment of Mg for different medical reasons.
文摘Purpose: We aimed to evaluate 458 infants, who were followed up due to retinopathy of prematurity (ROP), demographically and epidemiologically. Methods: 458 infants with ROP, who were referred from our hospital’s neonatal intensive care unit and from other health centers to our clinic for the staging and treatment between February 2016 and December 2017, were studied retrospectively. Design: Retrospective-observational study. Results: Of the 458 infants, 243 infants (53.06%) did not have ROP and they were at a mean of 32nd (26 - 35) gestational week, weighing a mean of 1700 (820 - 2830) gr. The remaining 215 (46.94%) infants were diagnosed with ROP at various stages and they were at a mean of 29th (23 - 35) gestational week, weighing a mean of 1180 (490 - 2850) gr. Of the infants without ROP, 116 (47.7%) were females and 127 (52.3%) were males. The mean duration of stay at the incubator was a mean of 16.5 (0 - 120) days and the mean duration of follow-up was a mean of 43 (40 - 56) weeks. 103 (40.2%) of them were breastfed only. Of the infants with ROP at various stages, 95 (44.2%) were females, and 120 (55.8%) were males. The mean duration of stay at the incubator was 42 (6 - 195) days, and the mean duration of follow-up was 48 (40 - 73) weeks. 43 (20.0%) of them were breastfed only. 32 (13.2%) infants without ROP were born of multi-fetal pregnancies. Only 1 of them was born as one of the triplets. Of the babies with ROP;56 (26.04%) were born of multi-fetal pregnancies, 5 of them being triplets. The numerical values of the gestational week at birth and the birth weight, and the rates of breastfeeding were lower in infants with ROP compared to the ones without it (p 0.05, Conclusions: This study showed that the gestational age, birth weight, breastfeeding rates, birth history and follow-up periods of multiple fetal pregnancies were different in ROP infants compared to non-ROP infants.
文摘Purpose: Retinopathy of prematurity (ROP), an abnormal proliferation of retinal vessels in premature infants with low birth weight, develops due to many factors. This study investigated a possible correlation between haematological parameters and ROP development. Method: This study included 189 infants without ROP and 128 with ROP. All were born at 35 weeks’ gestation or earlier, had a CBC drawn within 72 hours of birth, and had haemogram data for the first month. Haemoglobin (Hb), haematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), red cell distribution width (RDW), platelet counts (PLT), mean platelet volume (MPV) and platelet distribution width (PDW) values were obtained from hospital data and retrospectively analysed. Results: The mean gestational age was 31 weeks and 29 weeks for the control and ROP groups, respectively;the mean birth weights were 1757 g and 1332 g, respectively. The ROP group’s birth Hb, MCV and RDW were significantly lower than the control group (p p p p Conclusion: Premature infants with ROP had lower Hb and increased platelet, MPV and PDW in early postnatal life than infants without ROP. In the first month, when ROP develops, low PLT, PDW and Hb and high MPV could be indicators for ROP diagnosis, follow-up and treatment.
