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Traumatic brain injury and variants of shock index
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作者 Sai Doppalapudi muhammad adrish 《World Journal of Critical Care Medicine》 2024年第3期1-4,共4页
Traumatic Brain Injury is a major cause of death and long-term disability.The early identification of patients at high risk of mortality is important for both management and prognosis.Although many modified scoring sy... Traumatic Brain Injury is a major cause of death and long-term disability.The early identification of patients at high risk of mortality is important for both management and prognosis.Although many modified scoring systems have been developed for improving the prediction accuracy in patients with trauma,few studies have focused on prediction accuracy and application in patients with traumatic brain injury.The shock index(SI)which was first introduced in the 1960s has shown to strongly correlate degree of circulatory shock with increasing SI.In this editorial we comment on a publication by Carteri et al wherein they perform a retrospective analysis studying the predictive potential of SI and its variants in populations with severe traumatic brain injury. 展开更多
关键词 Predictive tools Traumatic brain injury Shock index Neurocardiogenic stress Myocardial ischemia
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Reimagining critical care:Trends and shifts in 21st century medicine
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作者 Sai Doppalapudi Bilal Khan muhammad adrish 《World Journal of Critical Care Medicine》 2024年第3期5-10,共6页
primarily driven by advancements in technology,changes in healthcare delivery,and a deeper understanding of disease processes.Advancements in technology have revolutionized patient monitoring,diagnosis,and treatment i... primarily driven by advancements in technology,changes in healthcare delivery,and a deeper understanding of disease processes.Advancements in technology have revolutionized patient monitoring,diagnosis,and treatment in the critical care setting.From minimally invasive procedures to advances imaging techniques,clinicians now have access to a wide array of tools to assess and manage critically ill patients more effectively.In this editorial we comment on the review article published by Padte S et al wherein they concisely describe the latest developments in critical care medicine. 展开更多
关键词 Artificintelligenceial VENTILATORS Extracorporeal organ support TELEMEDICINE Critical care
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Community-acquired pneumonia:The importance of the early detection of drug-resistant organisms
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作者 Sai Doppalapudi muhammad adrish 《World Journal of Critical Care Medicine》 2024年第2期11-14,共4页
Pneumonia is a disease associated with significant healthcare burden with over 1.5 million hospitalizations annually and is the eighth leading cause of death in the United States.While community-acquired pneumonia(CAP... Pneumonia is a disease associated with significant healthcare burden with over 1.5 million hospitalizations annually and is the eighth leading cause of death in the United States.While community-acquired pneumonia(CAP)is generally considered an acute time-limited illness,it is associated with high long-term mortality,with nearly one-third of patients requiring hospitalization dying within one year.An increasing trend of detecting multidrug-resistant(MDR)organisms causing CAP has been observed,especially in the Western world.In this editorial,we discuss about a publication by Jatteppanavar et al which reported that a case of a MDR organism was the culprit in developing pneumonia,bacteremia,and infective endocarditis that led to the patient’s death.The early detection of these resistant organisms helps improve patient outcomes.Significant advances have been made in the biotechnological and research space,but preventive measures,diagnostic techniques,and treatment strategies need to be developed. 展开更多
关键词 Methicillin-resistant Staphylococcus aureus Polymerase chain reaction Antibiotic resistance Bacterial colonization Infective endocarditis
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Driving pressure decoded:Precision strategies in adult respiratory distress syndrome management
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作者 muhammad adrish Sai Doppalapudi Dmitry Lvovsky 《World Journal of Critical Care Medicine》 2024年第2期15-18,共4页
Mechanical ventilation(MV)is an important strategy for improving the survival of patients with respiratory failure.However,MV is associated with aggravation of lung injury,with ventilator-induced lung injury(VILI)beco... Mechanical ventilation(MV)is an important strategy for improving the survival of patients with respiratory failure.However,MV is associated with aggravation of lung injury,with ventilator-induced lung injury(VILI)becoming a major concern.Thus,ventilation protection strategies have been developed to minimize complications from MV,with the goal of relieving excessive breathing workload,improving gas exchange,and minimizing VILI.By opting for lower tidal volumes,clinicians seek to strike a balance between providing adequate ventilation to support gas exchange and preventing overdistension of the alveoli,which can contribute to lung injury.Additionally,other factors play a role in optimizing lung protection during MV,including adequate positive end-expiratory pressure levels,to maintain alveolar recruitment and prevent atelectasis as well as careful consideration of plateau pressures to avoid excessive stress on the lung parenchyma. 展开更多
关键词 Driving pressure Mechanical ventilation Lung-protective ventilation strategies Ventilator-induced lung injury
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