Pristine phase change materials(PCMs)suffer from inherent deficiencies of poor solar absorption and photothermal conversion.Herein,we proposed a strategy of co-incorporation of zero-dimensional(OD)metal nanoparticles ...Pristine phase change materials(PCMs)suffer from inherent deficiencies of poor solar absorption and photothermal conversion.Herein,we proposed a strategy of co-incorporation of zero-dimensional(OD)metal nanoparticles and two-dimensional(2D)photothermal materials in PCMs for efficient capture and conversion of solar energy into thermal energy.Highly scattered Co-anchored MoS_(2)nanoflower cluster serving as photon and phonon triggers was prepared by in-situ hydrothermal growth of ZIF67 polyhedron on 2D MoS_(2)and subsequent high-temperature carbonization.After encapsulating thermal storage unit(paraffin wax),the obtained composite PCMs integrated high-performance photothermal conversion and thermal energy storage capability.Benefiting from the synergistic enhancement of OD Co nanoparticles with localized surface plasmon resonance effect,carbon layer with the conjugation effect and 2D MoS_(2)with strong solar absorption,composite PCMs exhibited a high photothermal conversion efficiency of 95.19%,Additionally,the resulting composite PCMs also demonstrated long-term thermal sto rage stability and durable structu ral stability after 300 thermal cycles.The proposed collabo rative co-incorporation strategy provides some innovative references for developing next-generation photothermal PCMs in solar energy utilization.展开更多
diabetes mellitus(DM)is a disease syndrome characterized by chronic hyperglycaemia.A long-term high-glucose environment leads to reactive oxygen species(ROS)production and nuclear DNA damage.human umbilical cord mesen...diabetes mellitus(DM)is a disease syndrome characterized by chronic hyperglycaemia.A long-term high-glucose environment leads to reactive oxygen species(ROS)production and nuclear DNA damage.human umbilical cord mesenchymal stem cell(HUcMSC)infusion induces significant antidiabetic effects in type 2 diabetes mellitus(T2DM)rats.Insulin-like growth factor 1(IGF1)receptor(IGF1R)is important in promoting glucose metabolism in diabetes;however,the mechanism by which HUcMSC can treat diabetes through IGF1R and DNA damage repair remains unclear.In this study,a DM rat model was induced with high-fat diet feeding and streptozotocin(STZ)administration and rats were infused four times with HUcMSC.Blood glucose,interleukin-6(IL-6),IL-10,glomerular basement membrane,and renal function were examined.Proteins that interacted with IGF1R were determined through coimmunoprecipitation assays.The expression of IGF1R,phosphorylated checkpoint kinase 2(p-CHK2),and phosphorylated protein 53(p-p53)was examined using immunohistochemistry(IHC)and western blot analysis.Enzyme-linked immunosorbent assay(ELISA)was used to determine the serum levels of 8-hydroxydeoxyguanosine(8-OHdG).Flow cytometry experiments were used to detect the surface markers of HUcMSC.The identification of the morphology and phenotype of HUcMSC was performed by way of oil red“O”staining and Alizarin red staining.DM rats exhibited abnormal blood glucose and IL-6/10 levels and renal function changes in the glomerular basement membrane,increased the expression of IGF1 and IGF1R.IGF1R interacted with CHK2,and the expression of p-CHK2 was significantly decreased in IGF1R-knockdown cells.When cisplatin was used to induce DNA damage,the expression of p-CHK2 was higher than that in the IGF1R-knockdown group without cisplatin treatment.HUcMSC infusion ameliorated abnormalities and preserved kidney structure and function in DM rats.The expression of IGF1,IGF1R,p-CHK2,and p-p53,and the level of 8-OHdG in the DM group increased significantly compared with those in the control group,and decreased after HUcMSC treatment.Our results suggested that IGF1R could interact with CHK2 and mediate DNA damage.HUcMSC infusion protected against kidney injury in DM rats.The underlying mechanisms may include HUcMSC-mediated enhancement of diabetes treatment via the IGF1R-CHK2-p53 signalling pathway.展开更多
Thin-film flexible solar cells are lightweight and mechanically robust.Along with rapidly advancing battery technology,flexible solar panels are expected to create niche products that require lightweight,mechanical fl...Thin-film flexible solar cells are lightweight and mechanically robust.Along with rapidly advancing battery technology,flexible solar panels are expected to create niche products that require lightweight,mechanical flexibility,and moldability into complex shapes,such as roof-panel for electric automobiles,foldable umbrellas,camping tents,etc.In this paper,we provide a comprehensive assessment of relevant materials suitable for making flexible solar cells.Substrate materials reviewed include metals,ceramics,glasses,and plastics.For active materials,we focus primarily on emerging new semiconductors including small organic donor/acceptor molecules,conjugated donor/acceptor polymers,and organometal halide perovskites.For electrode materials,transparent conducting oxides,thin metal films/nanowires,nanocarbons,and conducting polymers are reviewed.We also discuss the merits,weaknesses,and future perspectives of these materials for developing next-generation flexible photovoltaics.展开更多
In response to the rapid development of highly integrated multifunctional electronic devices,developing advanced multifunctional composite phase change materials(PCMs)that integrate thermal management,solar-thermal co...In response to the rapid development of highly integrated multifunctional electronic devices,developing advanced multifunctional composite phase change materials(PCMs)that integrate thermal management,solar-thermal conversion and microwave absorption has become increasingly essential.Herein,we propose a bionical strategy to design neural network-like(carbon nanofiber)CNF@Co/C aerogels by growing ZIF-67 in situ on bacterial cellulose(BC)and subsequent calcination strategies.After the encapsulation of thermal storage unit(paraffin wax,PW),the obtained multifunctional composite PCMs(PW-CNF@Co/C aerogel)are composed of“soma”(Co/C polyhedra),“axon”(porous CNF)and thermal storage unit(PW).Importantly,the composite PCMs show a high solar-thermal conversion efficiency of 95.27%benefiting from the synergism of“soma”with strong local surface plasmon resonance(LSPR)effect and“axon”with enhanced photon transmission path.More attractively,the composite PCMs also display good microwave absorption capacity with a minimum reflection loss(RL)of-26.8 dB at 10.91 GHz owing to the synergy of magnetic and dielectric components along with abundant polarization and multiple reflections.Our developed functionally integrated composite PCMs provide a prospective application of highly integrated and miniaturized electronic devices in complex and changeable outdoor environments.展开更多
The northwest of China is a vast area with abundant resources and significant potential for development.However,the ecological system is extremely vulnerable to damage and must be managed carefully.Thus,the Chinese go...The northwest of China is a vast area with abundant resources and significant potential for development.However,the ecological system is extremely vulnerable to damage and must be managed carefully.Thus,the Chinese government is strengthening research on improvement and reconstruction of the ecological system and landscape in northwest of China while moving forward with large-scale development in west China.The disadvantages and vulnerabilities in the northwest area in China are presented.It is suggested that the reconstruction of landscape should be conducted by step by step regionalization across the various ecological systems in the 3.04 million km^(2) northwest area of China.The first level regionalization results of reconstruction of landscape are discussed.展开更多
基金financially supported by National Natural Science Foundation of China(No.51902025)。
文摘Pristine phase change materials(PCMs)suffer from inherent deficiencies of poor solar absorption and photothermal conversion.Herein,we proposed a strategy of co-incorporation of zero-dimensional(OD)metal nanoparticles and two-dimensional(2D)photothermal materials in PCMs for efficient capture and conversion of solar energy into thermal energy.Highly scattered Co-anchored MoS_(2)nanoflower cluster serving as photon and phonon triggers was prepared by in-situ hydrothermal growth of ZIF67 polyhedron on 2D MoS_(2)and subsequent high-temperature carbonization.After encapsulating thermal storage unit(paraffin wax),the obtained composite PCMs integrated high-performance photothermal conversion and thermal energy storage capability.Benefiting from the synergistic enhancement of OD Co nanoparticles with localized surface plasmon resonance effect,carbon layer with the conjugation effect and 2D MoS_(2)with strong solar absorption,composite PCMs exhibited a high photothermal conversion efficiency of 95.19%,Additionally,the resulting composite PCMs also demonstrated long-term thermal sto rage stability and durable structu ral stability after 300 thermal cycles.The proposed collabo rative co-incorporation strategy provides some innovative references for developing next-generation photothermal PCMs in solar energy utilization.
基金supported by the Peak Disciplines(Type IV)of Institutions of Higher Learning in Shanghai,the Discipline Leader Program of Pudong New District Health and Family Planning Commission(No.PWRd2018-02)the Natural Science Foundation of Jiangxi Province(Nos.20181ACB20021 and 20181BAB205044),China.
文摘diabetes mellitus(DM)is a disease syndrome characterized by chronic hyperglycaemia.A long-term high-glucose environment leads to reactive oxygen species(ROS)production and nuclear DNA damage.human umbilical cord mesenchymal stem cell(HUcMSC)infusion induces significant antidiabetic effects in type 2 diabetes mellitus(T2DM)rats.Insulin-like growth factor 1(IGF1)receptor(IGF1R)is important in promoting glucose metabolism in diabetes;however,the mechanism by which HUcMSC can treat diabetes through IGF1R and DNA damage repair remains unclear.In this study,a DM rat model was induced with high-fat diet feeding and streptozotocin(STZ)administration and rats were infused four times with HUcMSC.Blood glucose,interleukin-6(IL-6),IL-10,glomerular basement membrane,and renal function were examined.Proteins that interacted with IGF1R were determined through coimmunoprecipitation assays.The expression of IGF1R,phosphorylated checkpoint kinase 2(p-CHK2),and phosphorylated protein 53(p-p53)was examined using immunohistochemistry(IHC)and western blot analysis.Enzyme-linked immunosorbent assay(ELISA)was used to determine the serum levels of 8-hydroxydeoxyguanosine(8-OHdG).Flow cytometry experiments were used to detect the surface markers of HUcMSC.The identification of the morphology and phenotype of HUcMSC was performed by way of oil red“O”staining and Alizarin red staining.DM rats exhibited abnormal blood glucose and IL-6/10 levels and renal function changes in the glomerular basement membrane,increased the expression of IGF1 and IGF1R.IGF1R interacted with CHK2,and the expression of p-CHK2 was significantly decreased in IGF1R-knockdown cells.When cisplatin was used to induce DNA damage,the expression of p-CHK2 was higher than that in the IGF1R-knockdown group without cisplatin treatment.HUcMSC infusion ameliorated abnormalities and preserved kidney structure and function in DM rats.The expression of IGF1,IGF1R,p-CHK2,and p-p53,and the level of 8-OHdG in the DM group increased significantly compared with those in the control group,and decreased after HUcMSC treatment.Our results suggested that IGF1R could interact with CHK2 and mediate DNA damage.HUcMSC infusion protected against kidney injury in DM rats.The underlying mechanisms may include HUcMSC-mediated enhancement of diabetes treatment via the IGF1R-CHK2-p53 signalling pathway.
基金Z.H.Lu would like to acknowledge the Natural Science and Engineering Research Council of Canada,and the National Natural Science Foundation of China(Grant No.11774304)for providing research fund.H.Y.Yu would like to acknowledge the financial support by Research and Application of Key Technologies of GaN-based Power Devices on Si Substrate(Grant No:2019B010128001)Research on key technologies for optimization of IoT chips and product development(Grant No.2019B010142001)+1 种基金and Study and optimization of electrostatic discharge mechanism for GaN HEMT devices(Grant No:JCYJ20180305180619573)Research of AlGaN HEMT MEMS sensor for work in extreme environment(Grant No:JCYJ20170412153356899).
文摘Thin-film flexible solar cells are lightweight and mechanically robust.Along with rapidly advancing battery technology,flexible solar panels are expected to create niche products that require lightweight,mechanical flexibility,and moldability into complex shapes,such as roof-panel for electric automobiles,foldable umbrellas,camping tents,etc.In this paper,we provide a comprehensive assessment of relevant materials suitable for making flexible solar cells.Substrate materials reviewed include metals,ceramics,glasses,and plastics.For active materials,we focus primarily on emerging new semiconductors including small organic donor/acceptor molecules,conjugated donor/acceptor polymers,and organometal halide perovskites.For electrode materials,transparent conducting oxides,thin metal films/nanowires,nanocarbons,and conducting polymers are reviewed.We also discuss the merits,weaknesses,and future perspectives of these materials for developing next-generation flexible photovoltaics.
基金supported by the National Natural Science Foundation of China(No.51902025).
文摘In response to the rapid development of highly integrated multifunctional electronic devices,developing advanced multifunctional composite phase change materials(PCMs)that integrate thermal management,solar-thermal conversion and microwave absorption has become increasingly essential.Herein,we propose a bionical strategy to design neural network-like(carbon nanofiber)CNF@Co/C aerogels by growing ZIF-67 in situ on bacterial cellulose(BC)and subsequent calcination strategies.After the encapsulation of thermal storage unit(paraffin wax,PW),the obtained multifunctional composite PCMs(PW-CNF@Co/C aerogel)are composed of“soma”(Co/C polyhedra),“axon”(porous CNF)and thermal storage unit(PW).Importantly,the composite PCMs show a high solar-thermal conversion efficiency of 95.27%benefiting from the synergism of“soma”with strong local surface plasmon resonance(LSPR)effect and“axon”with enhanced photon transmission path.More attractively,the composite PCMs also display good microwave absorption capacity with a minimum reflection loss(RL)of-26.8 dB at 10.91 GHz owing to the synergy of magnetic and dielectric components along with abundant polarization and multiple reflections.Our developed functionally integrated composite PCMs provide a prospective application of highly integrated and miniaturized electronic devices in complex and changeable outdoor environments.
文摘The northwest of China is a vast area with abundant resources and significant potential for development.However,the ecological system is extremely vulnerable to damage and must be managed carefully.Thus,the Chinese government is strengthening research on improvement and reconstruction of the ecological system and landscape in northwest of China while moving forward with large-scale development in west China.The disadvantages and vulnerabilities in the northwest area in China are presented.It is suggested that the reconstruction of landscape should be conducted by step by step regionalization across the various ecological systems in the 3.04 million km^(2) northwest area of China.The first level regionalization results of reconstruction of landscape are discussed.
