Cyanea nozakii,a common jellyfish distributed in offshore China,has a complex trophic relationship with other zooplankton groups.However,few studies have reported the predation rates and prey selection patterns of C.n...Cyanea nozakii,a common jellyfish distributed in offshore China,has a complex trophic relationship with other zooplankton groups.However,few studies have reported the predation rates and prey selection patterns of C.nozakii medusae on different prey items.Research is also lacking on the intraguild predation of Aurelia coerulea(another common bloom jellyfish in offshore China)by C.nozakii.To address the knowledge gaps,the clearance rates of C.nozakii for different prey items,including copepods(small<1000μm and large>1000μm),fish larvae,and gelatinous prey(hydromedusae,A.coerulea ephyrae,and chaetognaths),were measured.The influence of predator size on the clearance rate was also determined.Additionally,we examined the intraguild predation of C.nozakii on A.coerulea medusae.The clearance rates of C.nozakii varied widely with prey organisms,being independent of prey concentrations.Gelatinous organisms,except for chaetognaths,were captured with considerably high efficiency,followed by fish larvae and copepods,indicating the preferential prey selection of gelatinous organisms by C.nozakii.The clearance rate increased linearly with the cross-sectional area of C.nozakii.Body size in medusae may,to some extents,underpin their capacity to capture more prey by increasing the encounter rate and capture success through ontogeny.C.nozakii preyed voraciously on A.coerulea in high feeding efficiency,but the clearance rate decreased with increasing A.coerulea(as prey)size.This phenomenon of intraguild predation suggests a speculative hypothesis of potential population regulation of A.coerulea by C.nozakii.The information regarding the feeding ecology of C.nozakii reported in this study is important for understanding plankton dynamics in marine ecosystems with extensive occurrences of this jellyfish.展开更多
Objective:An increasing number of pediatric patients are being diagnosed with anti-N-methyl-Daspartate receptor(NMDAR)encephalitis,whose treatment requires immunotherapy through nursing interventions.This study aimed ...Objective:An increasing number of pediatric patients are being diagnosed with anti-N-methyl-Daspartate receptor(NMDAR)encephalitis,whose treatment requires immunotherapy through nursing interventions.This study aimed to analyze the clinical features and long-term prognosis of pediatric anti-NMDAR encephalitis and to gather nursing experiences of immunotherapy.Methods:Seventeen children diagnosed with anti-NMDAR encephalitis were admitted to the pediatric department.They were subjected to a therapy of intravenous immunoglobulin(IVIG)accompanied with high-dose methylprednisolone(HDMP).Multidisciplinary cooperation and intensive care were used to manage them.The effects of nursing intervention and therapy were repeatedly assessed and analyzed throughout the course of treatment and recovery.Results:None of the patients manifested adverse drug reaction(ADR)during IVIG administration.At the first administration of HDMP,ADRs were promptly and efficiently treated in four patients(24%;i.e.,one case each of hyperglycosemia,hypertension,aggravated symptoms,and gastrointestinal bleed).Two patients underwent rehabilitation,and six patients received hyperbaric oxygenation during hospitalization.Nine patients with indwelling gastric tubes experienced four times of unplanned extubation.Hospital stay ranged from 11 days to 59 days,with the mean duration of 26 days.Discharge evaluation revealed that 16 patients who scored 0e2 on the modified Rankin scale presented obvious remission,and one patient who had a mRS score of 4 exhibited less improvement.The mRS scores of hospitalization,discharge,and six-month follow-up displayed statistically significant differences.Conclusions:Nursing interventions of immunotherapy ensures the security of IVIG administration.Multidisciplinary cooperation promotes remission.Our findings can serve as reference for healthcare teams.展开更多
Importance:The safety and efficacy of the bath-plug technique for the closure of cerebrospinal fluid(CSF)leaks in children remain unknown.Objective:We undertook this study to ascertain whether the bath-plug technique ...Importance:The safety and efficacy of the bath-plug technique for the closure of cerebrospinal fluid(CSF)leaks in children remain unknown.Objective:We undertook this study to ascertain whether the bath-plug technique was safe and effective for the repair of CSF leaks.Methods:We retrospectively reviewed patients who underwent endoscopic repair of CSF leaks with the fat graft as a plug-in at Beijing Children’s Hospital from March 2016 to May 2020.Demographic data,medical history,defect sites and sizes,interventions,and clinical outcomes were analyzed.One representative clinical case was additionally selected to highlight the procedure and the healing process.Results:A total of 18 pediatric patients were included in this study.The group was composed of 11 boys and seven girls,aged from 5 to 123 months.The etiologies included congenital CSF leaks(n=9)and head trauma(n=9).Among all patients,12 fistulas(66.7%)were located at the cribriform plate area,two(11.1%)at the roof of the ethmoid sinuses,two(11.1%)in the sphenoid sinus,and two(11.1%)at the frontal sinus.The maximum diameters of fistulas ranged from 5 to 20 mm,with a median value of 8 mm.Encephaloceles were identified in 14(77.8%)patients.No hydrocephalus was recognized.All CSF leaks were successfully repaired with a bath-plug technique.Follow-up ranged from 50 to 70 months.No surgical complications were encountered in any patient.Interpretation:Bath-plug technique is safe and reliable for the endoscopic management of CSF leaks in children.Meticulous peri-operative preparations are important for pediatric patients.展开更多
Purpose The control network,which is a crucial component of the contemporary accelerator control system,connects all servers,workstations,PCs,and instruments at each station to exchange data and share resources.The se...Purpose The control network,which is a crucial component of the contemporary accelerator control system,connects all servers,workstations,PCs,and instruments at each station to exchange data and share resources.The security and reliability of the network directly affect the operating efficiency of the control system.It is essential to know the technology of packet capture,monitoring,and analysis in order to maintain the accelerator control network's healthy,safe,and dependable functioning.Methods In this article,IMPCAS NetAnalyzer,a novel and general accelerator control network analysis system,is developed using object-oriented C#language,multi-threading technology,as well as the SharpPcap link-layer network access packet capture and filtering engine.Results This system can capture and thoroughly analyze control network protocols,particularly the CA and PVA protocols in EPICS.It summarizes the status of the IOC server along with PV access data.Simultaneously,by importing its IP address information,any accelerator device may generate real-time alarms for irregular access IP.This enables regular accelerator individuals to quickly understand the network's operational status.Conclusion Finally,the system has been tested and validated on two heavy ion accelerator research facilities,SESRI(the Practical Application in Space Environment Simulation and Research Infrastructure)and HIRFL(the Heavy Ion Research Facility in Lanzhou).The results indicate that it achieves the desired aims and serves as a solid foundation for future version development.展开更多
The connections between urinary organophosphate ester(OPE)metabolites and child growth have been identified in prior research,but there is currently a dearth of epidemiological evidence regarding the sex-specific impa...The connections between urinary organophosphate ester(OPE)metabolites and child growth have been identified in prior research,but there is currently a dearth of epidemiological evidence regarding the sex-specific impact of OPEs on child growth trajectories.This study enrolled 804 maternal-child pairs,and five OPE congeners were quantified in maternal serum during pregnancy.In this study,the impact of prenatal OPE exposure on child growth trajectories was assessed using linear mixed-effect models and a group-based trajectory model(GBTM),with consideration given to sex-specific effects.Fetuses were frequently exposed to OPEs in utero,and tris(2-butoxyethel)phosphate(TBEP)exhibited the highest concentration levels in maternal serum.Among male children,an increase of 2.72 ng/g lipid in TBEP concentration was associated with a 0.11-unit increase in head circumference-for-age z-score(HCAZ),and the effect was mainly concentrated at 1 and 2 months of age.Among female children,an increase of 2.72 ng/g lipid in tris(2-chloro-1-(chloromethyl)ethyl)phosphate(TDCPP)concentration was associated with a 0.15-unit increase in length-for-age z-score(LAZ)and a 0.14-unit increase in weight-for-age z-score(WAZ),and the effects were mainly concentrated at 9 months of age.For HCAZ trajectories,higher prenatal TBEP exposure was associated with higher odds for the fast growth group in male children.For the LAZ and WAZ trajectories,higher prenatal TDCPP exposure was associated with higher odds for the fast growth group in female children.The trajectory analysis approach provided insight into the complex associations between OPE exposure and child growth.展开更多
Experimental alloys with compositions of Mg(25-x)YxNi9Cu(x=0,1,3,5,7)have been successfully prepared through melt spinning method.The phase compositions and microstructures were measured by X-Ray diffraction(XRD)and h...Experimental alloys with compositions of Mg(25-x)YxNi9Cu(x=0,1,3,5,7)have been successfully prepared through melt spinning method.The phase compositions and microstructures were measured by X-Ray diffraction(XRD)and high-resolution transmission electron microscopy(HRTEM).The de-/hydrogenation properties were measured by utilizing Sievert apparatus,differential scanning calorimetry(DSC)and thermal gravimetric analyzer(TGA)connected with a H2 detector.The Arrhenius and Kissinger methods were adopted to calculate their dehydrogenation activation energies.The results show that hydrogen absorption kinetics of the alloys notably decline while their hydrogen desorption kinetics conspicuously improve with spinning rate increasing.The dehydrogenation activation energy markedly decreases with spinning rate increasing,which makes the hydrogen desorption kinetics improve.The thermodynamic parameters(H and S absolute values)clearly decrease with spinning rate increasing.The hydrogen absorption capacity exhibits different trends with spinning rate rising.Specifically,hydrogen absorption capacity increases at the beginning and declines later for Y1 alloy,but that of Y7 alloy always decreases with spinning rate growing.展开更多
The influences of milling time and Ce content on the electrochemical property and micro structure of asmilled Mg1-xCexNi0.9Al0.1(x=0,0.02,0.04,0.06,0.08)+50 wt%Ni alloys were investigated systematically.The as-milled ...The influences of milling time and Ce content on the electrochemical property and micro structure of asmilled Mg1-xCexNi0.9Al0.1(x=0,0.02,0.04,0.06,0.08)+50 wt%Ni alloys were investigated systematically.The as-milled alloys have an outstanding activation property.The cycle stability conspicuously grows up with milling time and Ce proportion increasing.The capacity retention rate at 100 th cycle of x=0.02 alloy augments from 47% to 63% when prolonging milling time from 5 to 30 h and it grows from55% to 82% for the 30 h milled alloy with Ce content growing from 0 to 0.08.The discharge capacity of x=0.02 alloy grows up invariably with milling time prolonging,while that of the 30 h milled alloys has the maximal value of 578.4 mAh/g with Ce content increasing.Moreover,the electrochemical kinetic properties of alloys significantly improve with milling duration extending,while they have the maximal values with Ce proportion varying.展开更多
基金the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA19060203)the National Natural Science Foundation of China(Nos.42076166,42130411)+4 种基金the Natural Science Foundation of Shandong Province(No.ZR2021QD061)the CAS-CSIRO Project Fund(No.GJHZ1888)the Mount Tai Scholar Climbing Plan to Song SUNthe Innovation Team of Fishery Resources and Ecology in the Yellow Sea and Bohai Sea(No.2020TD01)the Hainan Province Basic and Applied Basic Research Program(Natural Science Field)High-Level Talent Project(No.2019RC353)。
文摘Cyanea nozakii,a common jellyfish distributed in offshore China,has a complex trophic relationship with other zooplankton groups.However,few studies have reported the predation rates and prey selection patterns of C.nozakii medusae on different prey items.Research is also lacking on the intraguild predation of Aurelia coerulea(another common bloom jellyfish in offshore China)by C.nozakii.To address the knowledge gaps,the clearance rates of C.nozakii for different prey items,including copepods(small<1000μm and large>1000μm),fish larvae,and gelatinous prey(hydromedusae,A.coerulea ephyrae,and chaetognaths),were measured.The influence of predator size on the clearance rate was also determined.Additionally,we examined the intraguild predation of C.nozakii on A.coerulea medusae.The clearance rates of C.nozakii varied widely with prey organisms,being independent of prey concentrations.Gelatinous organisms,except for chaetognaths,were captured with considerably high efficiency,followed by fish larvae and copepods,indicating the preferential prey selection of gelatinous organisms by C.nozakii.The clearance rate increased linearly with the cross-sectional area of C.nozakii.Body size in medusae may,to some extents,underpin their capacity to capture more prey by increasing the encounter rate and capture success through ontogeny.C.nozakii preyed voraciously on A.coerulea in high feeding efficiency,but the clearance rate decreased with increasing A.coerulea(as prey)size.This phenomenon of intraguild predation suggests a speculative hypothesis of potential population regulation of A.coerulea by C.nozakii.The information regarding the feeding ecology of C.nozakii reported in this study is important for understanding plankton dynamics in marine ecosystems with extensive occurrences of this jellyfish.
基金supported by the National Natural Science Foundation of China(21373185,41672033,21506188,21404090)the Open Project Programs of Engineering Research Center of Non-metallic Minerals of Zhejiang Province(ZD2015k07)+2 种基金of State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology(GCTKF2014006)of Key Laboratory of High Efficient Processing of Bamboo of Zhejiang Province(2016)of State Key Laboratory of Chemical Resource Engineering,Beijing University of Chemical Technology(CRE-2016-C-303)~~
基金We thank the First Affiliated Hospital of the Guangxi Medical University for supplying the case data.We also thank teachers in the pediatric department for their assistance.
文摘Objective:An increasing number of pediatric patients are being diagnosed with anti-N-methyl-Daspartate receptor(NMDAR)encephalitis,whose treatment requires immunotherapy through nursing interventions.This study aimed to analyze the clinical features and long-term prognosis of pediatric anti-NMDAR encephalitis and to gather nursing experiences of immunotherapy.Methods:Seventeen children diagnosed with anti-NMDAR encephalitis were admitted to the pediatric department.They were subjected to a therapy of intravenous immunoglobulin(IVIG)accompanied with high-dose methylprednisolone(HDMP).Multidisciplinary cooperation and intensive care were used to manage them.The effects of nursing intervention and therapy were repeatedly assessed and analyzed throughout the course of treatment and recovery.Results:None of the patients manifested adverse drug reaction(ADR)during IVIG administration.At the first administration of HDMP,ADRs were promptly and efficiently treated in four patients(24%;i.e.,one case each of hyperglycosemia,hypertension,aggravated symptoms,and gastrointestinal bleed).Two patients underwent rehabilitation,and six patients received hyperbaric oxygenation during hospitalization.Nine patients with indwelling gastric tubes experienced four times of unplanned extubation.Hospital stay ranged from 11 days to 59 days,with the mean duration of 26 days.Discharge evaluation revealed that 16 patients who scored 0e2 on the modified Rankin scale presented obvious remission,and one patient who had a mRS score of 4 exhibited less improvement.The mRS scores of hospitalization,discharge,and six-month follow-up displayed statistically significant differences.Conclusions:Nursing interventions of immunotherapy ensures the security of IVIG administration.Multidisciplinary cooperation promotes remission.Our findings can serve as reference for healthcare teams.
基金National Clinical Research Center for Respiratory Diseases(HXZX-20210501)
文摘Importance:The safety and efficacy of the bath-plug technique for the closure of cerebrospinal fluid(CSF)leaks in children remain unknown.Objective:We undertook this study to ascertain whether the bath-plug technique was safe and effective for the repair of CSF leaks.Methods:We retrospectively reviewed patients who underwent endoscopic repair of CSF leaks with the fat graft as a plug-in at Beijing Children’s Hospital from March 2016 to May 2020.Demographic data,medical history,defect sites and sizes,interventions,and clinical outcomes were analyzed.One representative clinical case was additionally selected to highlight the procedure and the healing process.Results:A total of 18 pediatric patients were included in this study.The group was composed of 11 boys and seven girls,aged from 5 to 123 months.The etiologies included congenital CSF leaks(n=9)and head trauma(n=9).Among all patients,12 fistulas(66.7%)were located at the cribriform plate area,two(11.1%)at the roof of the ethmoid sinuses,two(11.1%)in the sphenoid sinus,and two(11.1%)at the frontal sinus.The maximum diameters of fistulas ranged from 5 to 20 mm,with a median value of 8 mm.Encephaloceles were identified in 14(77.8%)patients.No hydrocephalus was recognized.All CSF leaks were successfully repaired with a bath-plug technique.Follow-up ranged from 50 to 70 months.No surgical complications were encountered in any patient.Interpretation:Bath-plug technique is safe and reliable for the endoscopic management of CSF leaks in children.Meticulous peri-operative preparations are important for pediatric patients.
基金supported by High Intensity Heavy-ion Accelerator Facility(HIAF)approved by the National Development and Reform Commission of China.
文摘Purpose The control network,which is a crucial component of the contemporary accelerator control system,connects all servers,workstations,PCs,and instruments at each station to exchange data and share resources.The security and reliability of the network directly affect the operating efficiency of the control system.It is essential to know the technology of packet capture,monitoring,and analysis in order to maintain the accelerator control network's healthy,safe,and dependable functioning.Methods In this article,IMPCAS NetAnalyzer,a novel and general accelerator control network analysis system,is developed using object-oriented C#language,multi-threading technology,as well as the SharpPcap link-layer network access packet capture and filtering engine.Results This system can capture and thoroughly analyze control network protocols,particularly the CA and PVA protocols in EPICS.It summarizes the status of the IOC server along with PV access data.Simultaneously,by importing its IP address information,any accelerator device may generate real-time alarms for irregular access IP.This enables regular accelerator individuals to quickly understand the network's operational status.Conclusion Finally,the system has been tested and validated on two heavy ion accelerator research facilities,SESRI(the Practical Application in Space Environment Simulation and Research Infrastructure)and HIRFL(the Heavy Ion Research Facility in Lanzhou).The results indicate that it achieves the desired aims and serves as a solid foundation for future version development.
基金supported by the National Key Research and Development Program of China(Grant No.2022YFC2705004)the National Natural Science Foundation of China(Grant No.82273585)Key Project on Science and Technology Program of Fujian Health Commission(Gran No.2021ZD01002).
文摘The connections between urinary organophosphate ester(OPE)metabolites and child growth have been identified in prior research,but there is currently a dearth of epidemiological evidence regarding the sex-specific impact of OPEs on child growth trajectories.This study enrolled 804 maternal-child pairs,and five OPE congeners were quantified in maternal serum during pregnancy.In this study,the impact of prenatal OPE exposure on child growth trajectories was assessed using linear mixed-effect models and a group-based trajectory model(GBTM),with consideration given to sex-specific effects.Fetuses were frequently exposed to OPEs in utero,and tris(2-butoxyethel)phosphate(TBEP)exhibited the highest concentration levels in maternal serum.Among male children,an increase of 2.72 ng/g lipid in TBEP concentration was associated with a 0.11-unit increase in head circumference-for-age z-score(HCAZ),and the effect was mainly concentrated at 1 and 2 months of age.Among female children,an increase of 2.72 ng/g lipid in tris(2-chloro-1-(chloromethyl)ethyl)phosphate(TDCPP)concentration was associated with a 0.15-unit increase in length-for-age z-score(LAZ)and a 0.14-unit increase in weight-for-age z-score(WAZ),and the effects were mainly concentrated at 9 months of age.For HCAZ trajectories,higher prenatal TBEP exposure was associated with higher odds for the fast growth group in male children.For the LAZ and WAZ trajectories,higher prenatal TDCPP exposure was associated with higher odds for the fast growth group in female children.The trajectory analysis approach provided insight into the complex associations between OPE exposure and child growth.
基金This work was supported by the National Natural Science Foundation of China （61475085）, Science and Technology Development Project of Shandong Province （2014GGX101007）, and the Fundamental Research Funds of Shandong University （2014YQ011）.
基金the National Natural Science Foundations of China (Nos. 51761032, 51871125 and 51471054) for financial support of the work
文摘Experimental alloys with compositions of Mg(25-x)YxNi9Cu(x=0,1,3,5,7)have been successfully prepared through melt spinning method.The phase compositions and microstructures were measured by X-Ray diffraction(XRD)and high-resolution transmission electron microscopy(HRTEM).The de-/hydrogenation properties were measured by utilizing Sievert apparatus,differential scanning calorimetry(DSC)and thermal gravimetric analyzer(TGA)connected with a H2 detector.The Arrhenius and Kissinger methods were adopted to calculate their dehydrogenation activation energies.The results show that hydrogen absorption kinetics of the alloys notably decline while their hydrogen desorption kinetics conspicuously improve with spinning rate increasing.The dehydrogenation activation energy markedly decreases with spinning rate increasing,which makes the hydrogen desorption kinetics improve.The thermodynamic parameters(H and S absolute values)clearly decrease with spinning rate increasing.The hydrogen absorption capacity exhibits different trends with spinning rate rising.Specifically,hydrogen absorption capacity increases at the beginning and declines later for Y1 alloy,but that of Y7 alloy always decreases with spinning rate growing.
基金Project supported by the National Natural Science Foundation of China (51761032 and 51871125)。
文摘The influences of milling time and Ce content on the electrochemical property and micro structure of asmilled Mg1-xCexNi0.9Al0.1(x=0,0.02,0.04,0.06,0.08)+50 wt%Ni alloys were investigated systematically.The as-milled alloys have an outstanding activation property.The cycle stability conspicuously grows up with milling time and Ce proportion increasing.The capacity retention rate at 100 th cycle of x=0.02 alloy augments from 47% to 63% when prolonging milling time from 5 to 30 h and it grows from55% to 82% for the 30 h milled alloy with Ce content growing from 0 to 0.08.The discharge capacity of x=0.02 alloy grows up invariably with milling time prolonging,while that of the 30 h milled alloys has the maximal value of 578.4 mAh/g with Ce content increasing.Moreover,the electrochemical kinetic properties of alloys significantly improve with milling duration extending,while they have the maximal values with Ce proportion varying.
基金This work was supported by Natural Science Foundation of China （60977058）, Science Fund for Distinguished Young Scholars of Shandong Province of China （JQ200819）, Research Award Fund for Outstanding Middle-aged＇ and Young Scientist of Shandong Province of China （2007BS08003）, Independent Innovation Foundation of Shandong University （IIFSDU2010JC002）.
