BACKGROUND There is a lack of studies on the effects of enhanced recovery after surgery(ERAS)with multidisciplinary collaboration on the nursing outcomes of total knee arthroplasty(TKA).AIM To explore the effect of ER...BACKGROUND There is a lack of studies on the effects of enhanced recovery after surgery(ERAS)with multidisciplinary collaboration on the nursing outcomes of total knee arthroplasty(TKA).AIM To explore the effect of ERAS with multidisciplinary collaboration on nursing outcomes after TKA.METHODS We retrospectively analyzed the clinical data of 80 patients who underwent TKA at a tertiary hospital between January 2021 and December 2022.The patients were divided into two groups according to the nursing mode:the ERAS group(n=40)received ERAS with multidisciplinary collaboration,and the conventional group(n=40)received routine nursing.The following indicators were compared between the two groups:length of hospital stay,hospitalization cost,intraoperative blood loss,hemoglobin level 24 h after surgery,visual analog scale(VAS)score for pain,range of motion(ROM)of the knee joint,Hospital for Special Surgery(HSS)knee score,and postoperative complications.RESULTS The ERAS group had a significantly shorter length of hospital stay,lower hospitalization cost,less intraoperative blood loss,higher hemoglobin level 24 h after surgery,lower VAS score for pain,higher knee joint ROM,and higher HSS knee score than the conventional group(all P<0.05).There was no significant difference in the incidence of postoperative complications between the two groups(P>0.05).CONCLUSION Multidisciplinary collaboration with ERAS can reduce blood loss,shorten hospital stay,and improve knee function in patients undergoing TKA.展开更多
Diabetic retinopathy is the most common microvascular complication of diabetes mellitus and the primary reason for blindness all over the world,which is a lesion of blood vessels,neurons,and glial cells that constitut...Diabetic retinopathy is the most common microvascular complication of diabetes mellitus and the primary reason for blindness all over the world,which is a lesion of blood vessels,neurons,and glial cells that constitute the complete structure of the retina.Patients may have vision loss and irreversible blindness.With the increase in the number of diabetes mellitus patients and the extension of lifespan,the incidence rate gradually increases.The clinical diagnosis of diabetic retinopathy mainly relies on regular examinations of ocular fundus and subjective patient descriptions,and once diabetic retinopathy is diagnosed,it is difficult to reverse.It is necessary to find the early markers of diabetic retinopathy.In this paper,data collection,data analysis of metabolomics and its research progress in diabetic retinopathy are summarized and prospected.In recent years,metabolomics has made some progress in the discovery of biomarkers,the exploration of pathogenesis,and the evaluation of diabetic retinopathyug efficacy of diabetic retinopathy.However,there are currently few metabolomics studies on the progression of diabetes mellitus to diabetic retinopathy.The determination of diabetic retinopathy-related specific biomarkers also requires data which a large number of animal experiments and clinical trials provide.In addition,despite the rapid development of metabolomics as an emerging discipline,there are still some problems,which need to be further improved in terms of analysis technology,data acquisition and data analysis.In general,there is still a lot of work to be done to apply metabolomics to clinical work.展开更多
文摘BACKGROUND There is a lack of studies on the effects of enhanced recovery after surgery(ERAS)with multidisciplinary collaboration on the nursing outcomes of total knee arthroplasty(TKA).AIM To explore the effect of ERAS with multidisciplinary collaboration on nursing outcomes after TKA.METHODS We retrospectively analyzed the clinical data of 80 patients who underwent TKA at a tertiary hospital between January 2021 and December 2022.The patients were divided into two groups according to the nursing mode:the ERAS group(n=40)received ERAS with multidisciplinary collaboration,and the conventional group(n=40)received routine nursing.The following indicators were compared between the two groups:length of hospital stay,hospitalization cost,intraoperative blood loss,hemoglobin level 24 h after surgery,visual analog scale(VAS)score for pain,range of motion(ROM)of the knee joint,Hospital for Special Surgery(HSS)knee score,and postoperative complications.RESULTS The ERAS group had a significantly shorter length of hospital stay,lower hospitalization cost,less intraoperative blood loss,higher hemoglobin level 24 h after surgery,lower VAS score for pain,higher knee joint ROM,and higher HSS knee score than the conventional group(all P<0.05).There was no significant difference in the incidence of postoperative complications between the two groups(P>0.05).CONCLUSION Multidisciplinary collaboration with ERAS can reduce blood loss,shorten hospital stay,and improve knee function in patients undergoing TKA.
文摘Diabetic retinopathy is the most common microvascular complication of diabetes mellitus and the primary reason for blindness all over the world,which is a lesion of blood vessels,neurons,and glial cells that constitute the complete structure of the retina.Patients may have vision loss and irreversible blindness.With the increase in the number of diabetes mellitus patients and the extension of lifespan,the incidence rate gradually increases.The clinical diagnosis of diabetic retinopathy mainly relies on regular examinations of ocular fundus and subjective patient descriptions,and once diabetic retinopathy is diagnosed,it is difficult to reverse.It is necessary to find the early markers of diabetic retinopathy.In this paper,data collection,data analysis of metabolomics and its research progress in diabetic retinopathy are summarized and prospected.In recent years,metabolomics has made some progress in the discovery of biomarkers,the exploration of pathogenesis,and the evaluation of diabetic retinopathyug efficacy of diabetic retinopathy.However,there are currently few metabolomics studies on the progression of diabetes mellitus to diabetic retinopathy.The determination of diabetic retinopathy-related specific biomarkers also requires data which a large number of animal experiments and clinical trials provide.In addition,despite the rapid development of metabolomics as an emerging discipline,there are still some problems,which need to be further improved in terms of analysis technology,data acquisition and data analysis.In general,there is still a lot of work to be done to apply metabolomics to clinical work.
