Background: This study aimed to illustrate the prevalence of CHD by screening children in extremely high-altitudeareas (over 4000 m to even 5000 m above sea level) and explore an aid model for early diagnosis and trea...Background: This study aimed to illustrate the prevalence of CHD by screening children in extremely high-altitudeareas (over 4000 m to even 5000 m above sea level) and explore an aid model for early diagnosis and treatmentfor the Tibetan population. Methods: A total of 2242 students from different schools in Ngamring County,Xigaze City, Tibet from September 2019 to September 2020 were selected for screening. The students were examinedthrough the inquiry of their current medical history and family history, cardiac auscultation and a physicalexamination, in order to screen out the suspected cases of CHD, and then the suspected cases were confirmed bycardiac color ultrasound examinations. After that, positive patients were be transferred to Shandong Province forfree treatment. Results: The prevalence of CHD among children in Ngamring County was 3.70% (83 cases),which is the highest incidence rate ever reported. The most common type of CHD was patent ductus arteriosus(PDA), accounting for 55.42% of the total number of cases screened, followed by atrial septal defect (ASD) andventricular septal defect (VSD), accounting for 28.92% and 12.05%, respectively. The prevalence of CHD in childrenat high altitude was significantly higher than that in children at low altitude. The children with CHD weretransferred to Shandong Province for surgery, the operations were successful and their recoveries went well.Conclusions: The results show that high altitude is closely related to the prevalence of CHD, and the incidencein Ngamring County is much higher than that in previous reports.展开更多
BACKGROUND There is no research on quantitative pleural line movement.In this study,we assume that tissue Doppler and its quantitative technology can quantify the pleural line movement and can be used to diagnose pneu...BACKGROUND There is no research on quantitative pleural line movement.In this study,we assume that tissue Doppler and its quantitative technology can quantify the pleural line movement and can be used to diagnose pneumothorax.AIM To evaluate the quantitative assessment of pleural line movement measured by tissue Doppler imaging(TDI)for pneumothorax diagnosis.METHODS Adult patients(n=45)diagnosed with unilateral pneumothorax were included in this study.Each patient underwent TDI of both lungs.The pneumothorax side and contralateral normal lung side were compared using several indices obtained from TDI:peak pleural line velocity(PV_(max)),peak chest wall tissue velocity(CV_(max)),peak pleural line strain value(PS_(max)),peak chest wall tissue strain value(CSmax),PV_(max)/CV_(max)and PS_(max)/CSmax.The receiver operating characteristic analysis was used to evaluate the performance of these quantitative assessments for pneumothorax diagnosis.RESULTS Various quantitative variables of the pneumothorax side were all lower than that of the non-pneumothorax side and included the PV_(max)(0.36 cm/s vs 0.59 cm/s,P<0.001),PS_(max)(1.14%vs 1.90%,P=0.001),PV_(max)/CV_(max)(1.06 vs 4.93,P<0.001),and PS_(max)/CSmax(0.76 vs 1.74,P<0.001).For the discrimination of pneumothorax,the cut-off values of the PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax were calculated as 0.50 cm/s,0.94%,1.96,and 1.12,respectively.Similarly,the sensitivities and specificities of PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax were 96%and 62%,47%and 91%,93%and 96%,and 82%and 93%,respectively.The area under the receiver operating characteristic curve were 0.84,0.72,0.99,and 0.91,respectively,for PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax.CONCLUSION Quantification analysis of pleural line movement using TDI is a useful tool for the diagnosis of pneumothorax.展开更多
文摘Background: This study aimed to illustrate the prevalence of CHD by screening children in extremely high-altitudeareas (over 4000 m to even 5000 m above sea level) and explore an aid model for early diagnosis and treatmentfor the Tibetan population. Methods: A total of 2242 students from different schools in Ngamring County,Xigaze City, Tibet from September 2019 to September 2020 were selected for screening. The students were examinedthrough the inquiry of their current medical history and family history, cardiac auscultation and a physicalexamination, in order to screen out the suspected cases of CHD, and then the suspected cases were confirmed bycardiac color ultrasound examinations. After that, positive patients were be transferred to Shandong Province forfree treatment. Results: The prevalence of CHD among children in Ngamring County was 3.70% (83 cases),which is the highest incidence rate ever reported. The most common type of CHD was patent ductus arteriosus(PDA), accounting for 55.42% of the total number of cases screened, followed by atrial septal defect (ASD) andventricular septal defect (VSD), accounting for 28.92% and 12.05%, respectively. The prevalence of CHD in childrenat high altitude was significantly higher than that in children at low altitude. The children with CHD weretransferred to Shandong Province for surgery, the operations were successful and their recoveries went well.Conclusions: The results show that high altitude is closely related to the prevalence of CHD, and the incidencein Ngamring County is much higher than that in previous reports.
文摘BACKGROUND There is no research on quantitative pleural line movement.In this study,we assume that tissue Doppler and its quantitative technology can quantify the pleural line movement and can be used to diagnose pneumothorax.AIM To evaluate the quantitative assessment of pleural line movement measured by tissue Doppler imaging(TDI)for pneumothorax diagnosis.METHODS Adult patients(n=45)diagnosed with unilateral pneumothorax were included in this study.Each patient underwent TDI of both lungs.The pneumothorax side and contralateral normal lung side were compared using several indices obtained from TDI:peak pleural line velocity(PV_(max)),peak chest wall tissue velocity(CV_(max)),peak pleural line strain value(PS_(max)),peak chest wall tissue strain value(CSmax),PV_(max)/CV_(max)and PS_(max)/CSmax.The receiver operating characteristic analysis was used to evaluate the performance of these quantitative assessments for pneumothorax diagnosis.RESULTS Various quantitative variables of the pneumothorax side were all lower than that of the non-pneumothorax side and included the PV_(max)(0.36 cm/s vs 0.59 cm/s,P<0.001),PS_(max)(1.14%vs 1.90%,P=0.001),PV_(max)/CV_(max)(1.06 vs 4.93,P<0.001),and PS_(max)/CSmax(0.76 vs 1.74,P<0.001).For the discrimination of pneumothorax,the cut-off values of the PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax were calculated as 0.50 cm/s,0.94%,1.96,and 1.12,respectively.Similarly,the sensitivities and specificities of PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax were 96%and 62%,47%and 91%,93%and 96%,and 82%and 93%,respectively.The area under the receiver operating characteristic curve were 0.84,0.72,0.99,and 0.91,respectively,for PV_(max),PS_(max),PV_(max)/CV_(max),and PS_(max)/CSmax.CONCLUSION Quantification analysis of pleural line movement using TDI is a useful tool for the diagnosis of pneumothorax.
