Magnetic semiconductors have attracted a lot of attention by having both electronic charge and spin degrees of freedom. In this paper, we obtained twenty magnetic semiconductors such as FeVLaSb, FeVPrSb, FeCrTbSi, CoV...Magnetic semiconductors have attracted a lot of attention by having both electronic charge and spin degrees of freedom. In this paper, we obtained twenty magnetic semiconductors such as FeVLaSb, FeVPrSb, FeCrTbSi, CoVDySi, and CoVHoSi by adding lanthanides to quaternary Heusler compounds based on the Slater-Pauling law and orbital hybridization theory. The relationship between the lattice constants and energy gaps of the magnetic semiconductors with lanthanide elements is investigated by in-depth analysis. These magnetic semiconductors of quaternary Heusler compounds are promising candidates to find applications as spin filtering materials in spintronics devices.展开更多
选择CNKI和Web of science数据库,通过文献计量学方法分析橄榄研究文献的发文量、国家、机构、基金、研究方向等指标,利用CiteSpace可视化功能进行作者、关键词共性分析,阐述橄榄研究热点和前沿动态。结果表明,橄榄研究自1995年后,进入...选择CNKI和Web of science数据库,通过文献计量学方法分析橄榄研究文献的发文量、国家、机构、基金、研究方向等指标,利用CiteSpace可视化功能进行作者、关键词共性分析,阐述橄榄研究热点和前沿动态。结果表明,橄榄研究自1995年后,进入高速发展阶段,2010年后橄榄相关SCI文献增长较快;对橄榄的研究以我国科研机构和专家学者为主,福建地方计划项目以及国家计划项目对橄榄研究资助较大,高质量文献产出较多的机构是福建农林大学、江南大学、福建农业科学院果树研究所;我国橄榄早期研究侧重生产实践应用,如良种选育、传统中药研究、果实贮藏等,随着科学技术快速发展,橄榄遗传多样性、功能基因、深加工、药用成分、药用机理方面的研究逐渐深入。展开更多
Objective:Current theories highlight the role of the microbiome in the pathogenesis of psoriasis.Additionally,abnormal metabolism can alter disease processes in terms of occurrence,progression,and prognosis.Therefore,...Objective:Current theories highlight the role of the microbiome in the pathogenesis of psoriasis.Additionally,abnormal metabolism can alter disease processes in terms of occurrence,progression,and prognosis.Therefore,an integrative microbiome and metabolome analysis of the skin may aid in understanding the disease pathogenesis and identify therapeutic targets for psoriasis.Methods:We recruited 22 patients with psoriasis and 22 age-and sex-matched healthy controls.Skin swabs were collected from the participants’scalps.All samples underwent amplicon sequencing of the internal transcribed spacer 1 and V3V416S rRNA regions and metabolome analysis.For amplicon data,analysis of the alpha diversities,microbial community structures and principal coordinate analysis were performed.Differential metabolites and pathway enrichment were analyzed for metabolome data.Studentt test and Wilcoxon rank sum test were used for statistical analysis.Results:The psoriatic lesions were characterized by higher bacterial diversity,significantly higher abundances ofCorynebacterium(P<0.001)andStaphylococcus(P=0.012),and a lower abundance ofCutibacterium(P<0.001)compared with healthy controls.However,no significant alterations in the fungal diversity or fungal taxonomies were detected.Metabolome analysis revealed that prostaglandin-related metabolites,nucleotides,and cysteine-and methionine-related metabolites were significantly enriched in patients with psoriasis,and these metabolites were positively correlated with the disease-associated bacteriaStaphylococcus andCorynebacterium.Conclusions:We demonstrated significant alterations in the skin microbiome and metabolome in patients with psoriasis compared with healthy controls.展开更多
基金Project supported by Inner Mongolia Science Foundation, China (Grant No. 2022MS01012)the National Natural Science Foundation of China (Grant No. 11904185)。
文摘Magnetic semiconductors have attracted a lot of attention by having both electronic charge and spin degrees of freedom. In this paper, we obtained twenty magnetic semiconductors such as FeVLaSb, FeVPrSb, FeCrTbSi, CoVDySi, and CoVHoSi by adding lanthanides to quaternary Heusler compounds based on the Slater-Pauling law and orbital hybridization theory. The relationship between the lattice constants and energy gaps of the magnetic semiconductors with lanthanide elements is investigated by in-depth analysis. These magnetic semiconductors of quaternary Heusler compounds are promising candidates to find applications as spin filtering materials in spintronics devices.
文摘选择CNKI和Web of science数据库,通过文献计量学方法分析橄榄研究文献的发文量、国家、机构、基金、研究方向等指标,利用CiteSpace可视化功能进行作者、关键词共性分析,阐述橄榄研究热点和前沿动态。结果表明,橄榄研究自1995年后,进入高速发展阶段,2010年后橄榄相关SCI文献增长较快;对橄榄的研究以我国科研机构和专家学者为主,福建地方计划项目以及国家计划项目对橄榄研究资助较大,高质量文献产出较多的机构是福建农林大学、江南大学、福建农业科学院果树研究所;我国橄榄早期研究侧重生产实践应用,如良种选育、传统中药研究、果实贮藏等,随着科学技术快速发展,橄榄遗传多样性、功能基因、深加工、药用成分、药用机理方面的研究逐渐深入。
基金supported by the National Natural Science Foundation of China(No.81903225)the Special Clinical Research for Young Scholar of Peking University First Hospital(No.2021CR20)。
文摘Objective:Current theories highlight the role of the microbiome in the pathogenesis of psoriasis.Additionally,abnormal metabolism can alter disease processes in terms of occurrence,progression,and prognosis.Therefore,an integrative microbiome and metabolome analysis of the skin may aid in understanding the disease pathogenesis and identify therapeutic targets for psoriasis.Methods:We recruited 22 patients with psoriasis and 22 age-and sex-matched healthy controls.Skin swabs were collected from the participants’scalps.All samples underwent amplicon sequencing of the internal transcribed spacer 1 and V3V416S rRNA regions and metabolome analysis.For amplicon data,analysis of the alpha diversities,microbial community structures and principal coordinate analysis were performed.Differential metabolites and pathway enrichment were analyzed for metabolome data.Studentt test and Wilcoxon rank sum test were used for statistical analysis.Results:The psoriatic lesions were characterized by higher bacterial diversity,significantly higher abundances ofCorynebacterium(P<0.001)andStaphylococcus(P=0.012),and a lower abundance ofCutibacterium(P<0.001)compared with healthy controls.However,no significant alterations in the fungal diversity or fungal taxonomies were detected.Metabolome analysis revealed that prostaglandin-related metabolites,nucleotides,and cysteine-and methionine-related metabolites were significantly enriched in patients with psoriasis,and these metabolites were positively correlated with the disease-associated bacteriaStaphylococcus andCorynebacterium.Conclusions:We demonstrated significant alterations in the skin microbiome and metabolome in patients with psoriasis compared with healthy controls.
