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One Case of Right Posterior Mediastinum Intraneural Hemangioma Misdiagnosed as Neurilemmoma
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作者 Xiaoxia Tan ruifen zhang Liangping Luo 《Journal of Biosciences and Medicines》 2024年第7期30-37,共8页
Although rare, intraneural hemangiomas should be considered in the differential diagnosis of peripheral nerve lesions. We report on a 59-year-old female patient, who was admitted to the hospital due to the discovery o... Although rare, intraneural hemangiomas should be considered in the differential diagnosis of peripheral nerve lesions. We report on a 59-year-old female patient, who was admitted to the hospital due to the discovery of bilateral breast masses for 3 months, there was no paresthesia or dyskinesia. The patient accidentally found a mass in the right upper mediastinum while completing a plain chest X-ray, initially suspected as a benign neurilemmoma on CT. Surgical resection and pathological analysis confirmed an intraneural hemangioma. Unexpectedly, the patient developed new-onset right upper limb numbness and paresthesia 3 months post-operatively, probably related to surgical nerve injury. This case underscores the importance of maintaining a broad differential for mediastinal masses, and the potential for iatrogenic neurological complications when managing these rare, yet vascular lesions. 展开更多
关键词 Intraneural Hemangioma Mediastinal Tumors Spinal Nerve
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Research Progress of Assessment Tools for Peripheral Venous Access Difficulties in Children
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作者 ruifen zhang Litao Xiao Jing Dong 《Journal of Clinical and Nursing Research》 2024年第6期86-89,共4页
Objective:To review the research progress of peripheral venous access difficulty assessment tools in children and to provide a reference for clinical nurses to select and develop appropriate assessment tools.Methods:S... Objective:To review the research progress of peripheral venous access difficulty assessment tools in children and to provide a reference for clinical nurses to select and develop appropriate assessment tools.Methods:Search the literature at home and abroad and summarize and analyze the existing evaluation tools.Results:There is no unified assessment tool about difficult venous access in children at home and abroad.The existing tools include the difficult venous access assessment scale and peripheral venous grading assessment tool.Conclusion:The current assessment tools for venous access difficulties in children have their own limitations,and it is necessary to develop further the assessment tools suitable for the cultural background of children's venous access difficulties.This paper summarized the current progress of research on peripheral venous access difficulty assessment tools.It also analyzed and summarized the shortcomings of existing tools to provide a reference for clinical staff to choose appropriate assessment tools. 展开更多
关键词 CHILDREN Difficult intravenous access Evaluation tools REVIEW
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Primary Cutaneous Apocrine Carcinoma of the Neck Involving the Parotid Gland: A Case Report and Review of the Literature
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作者 ruifen zhang Lingtao zhang Liangping Luo 《Journal of Biosciences and Medicines》 2023年第12期135-141,共7页
Introduction: Primary cutaneous apocrine carcinoma (PCAC) is a rare skin malignant tumor that originates from areas with a high concentration of apocrine glands. The incidence of PCAC in the neck is relatively low. Th... Introduction: Primary cutaneous apocrine carcinoma (PCAC) is a rare skin malignant tumor that originates from areas with a high concentration of apocrine glands. The incidence of PCAC in the neck is relatively low. The age of onset in PCAC ranges from 5 to 70 years old. Clinically, PCAC typically shows up as painless nodules or lumps. In immunohistochemistry, positive expression of CK-7, GCDFP-15, AR, and myoepithelial markers are helpful in the diagnosis of PCAC. This case report pertains to a 59-year-old male of Asian descent. Five years ago, a painless mass was discovered behind his right ear, which grew slowly. This patient was identified as PCAC based on clinical symptoms, pathology, immunohistochemistry, and imaging characteristics. PCAC involved the parotid gland in this case;it is easy to be misdiagnosed as a primary malignant tumor of the parotid gland on imaging. Furthermore, a thorough set of clinical, imaging, pathological, and immunohistochemical examinations must be performed to make a diagnosis because it is challenging to differentiate PCAC from metastatic breast carcinoma. Conclusion: A well-developed multidisciplinary examination is essential because PCAC can be challenging to diagnose and differentiate. 展开更多
关键词 Primary Cutaneous Apocrine Carcinoma Head and Neck Tumors Diagnostic Imaging
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Effects of Feixinning Capsules on BODE Index,CRP and Quality of Life in AECOPD Patients with Right Heart Failure
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作者 Yiqi WEN ruifen zhang He SU 《Medicinal Plant》 CAS 2021年第5期71-74,共4页
[Objectives]To investigate the therapeutic effect of Feixinning Capsules on acute exacerbation of chronic obstructive pulmonary disease(AECOPD)complicated with right heart failure.[Methods]A total of 60 cases of AECOP... [Objectives]To investigate the therapeutic effect of Feixinning Capsules on acute exacerbation of chronic obstructive pulmonary disease(AECOPD)complicated with right heart failure.[Methods]A total of 60 cases of AECOPD patients with right heart failure and phlegm-heat syndrome were randomly selected as the study subjects,and were divided into the Feixinning group(n=30)and the control group(n=30).The Feixinning group was treated with Feixinning Capsules combined with conventional western medicine,and the control group was treated with conventional western medicine.The pulmonary function,CRP,CAT score,BODE index item index,and EQ-5D index were compared between the two groups before and after treatment.[Results]After treatment,the pulmonary function,CRP,CAT score,6MWD,mMRC,BODE score and EQ-5D index in the Feixinning group were significantly improved compared with the control group(P<0.05),and there was no statistical difference in the change of BMI index(P>0.05).[Conclusions]Feixinning Capsules can effectively improve the clinical symptoms and quality of life of patients with AECOPD complicated with right heart failure and phlegm-heat syndrome. 展开更多
关键词 AECOPD Right heart failure Phlegm-heat syndrome Feixinning Capsules BODE index EQ-5d index
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黑芝麻多酚氧化酶的重组表达及其酶学特性 被引量:1
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作者 叶彩燕 刘光 +4 位作者 杜念 张瑞芬 刘磊 贾栩超 张名位 《生物工程学报》 CAS CSCD 北大核心 2021年第12期4395-4405,共11页
为明确黑芝麻多酚氧化酶的酶学性质,利用大肠杆菌Escherichia coli原核表达了黑芝麻多酚氧化酶(Black sesame polyphenol oxidase,BsPPO)。将合成的基因构建至pMAL-c5x载体,并在大肠杆菌中进行表达,对重组蛋白进行分离纯化及融合标签切... 为明确黑芝麻多酚氧化酶的酶学性质,利用大肠杆菌Escherichia coli原核表达了黑芝麻多酚氧化酶(Black sesame polyphenol oxidase,BsPPO)。将合成的基因构建至pMAL-c5x载体,并在大肠杆菌中进行表达,对重组蛋白进行分离纯化及融合标签切除,获得的BsPPO蛋白用于酶学性质探究。结果表明,合成的Bsppo基因1 752 bp,编码585个氨基酸,理论蛋白分子量为65.3 kDa;构建的pMAL-c5x-Bsppo重组质粒在大肠杆菌Escherichia coli BL21(DE3)中可溶表达了MBP-BsPPO蛋白;酶切去除MBP融合标签后对BsPPO进行了酶学性质研究,结果表明BsPPO的最适温度和pH分别为25℃和4.0,在低温和弱酸性环境中有较好的稳定性。短时间低强度的光照和Cu;可激活BsPPO的活性,Zn;和Ca;能抑制其活性。BsPPO可催化单酚、二酚以及三酚类化合物,对L-酪氨酸以及香草酸表现出较高的催化活性,此外BsPPO还对黑芝麻中含有的2-甲氧基肉桂酸、吲哚3-羧酸和根皮素表现出良好的催化活性。研究结果为黑芝麻多酚氧化酶酶学特性的明确奠定了理论基础。 展开更多
关键词 黑芝麻多酚氧化酶 大肠杆菌 原核表达 亲和纯化 酶学性质
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Non-equilibrium steady structures of confined liquid crystals driven by a dynamic boundary
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作者 ruifen zhang ChunLai Ren +1 位作者 JiaWei Feng YuQiang Ma 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS CSCD 2019年第11期115-124,共10页
Steady structures originating from dynamic self-assembly have begun to show their advantages in new generation materials, and pose challenges to equilibrium self-assembly. In view of the important role of confinement ... Steady structures originating from dynamic self-assembly have begun to show their advantages in new generation materials, and pose challenges to equilibrium self-assembly. In view of the important role of confinement in self-assembly, here, we propose a new type of confinement leading to dynamic steady structures, which opens a new window for the conventional confinement.In our model, we consider the self-assembly of ellipsoids in 2D circular confinement via the boundary performing periodically stretching and contracting oscillation. Langevin dynamics simulations reveal the achievement of non-equilibrium steady structures under appropriate boundary motions, which are novel smectic structures with stable topological defects. Different from the confinement with a static boundary, ellipsoids close to the boundary have variable orientations depending on the boundary motion.Order-order structural transitions, accompanied by the symmetry change and varied defect number, occur with the change of oscillating amplitude and/or frequency of the boundary. Slow and fast dynamics are distinguished according to whether structural rearrangements and energetic adjustment happen or not. The collective motion of confined ellipsoids, aroused by the work performed on the system, is the key factor determining both the structure and dynamics of the self-assembly. Our results not only achieve novel textures of circular confined liquid crystals, but also inspire us to reconsider the self-assembly within the living organisms. 展开更多
关键词 dynamic self-assembly CONFINED liquid crystals STEADY structure COLLECTIVE motion LANGEVIN dynamics simulation
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