Estimation for weather-related failure probability of overhead transmission lines is essential in the reliability assessment of a power system.This paper analyzes the outage and weather data of 110 kV overhead transmi...Estimation for weather-related failure probability of overhead transmission lines is essential in the reliability assessment of a power system.This paper analyzes the outage and weather data of 110 kV overhead transmission lines in the Guangxi Zhuang Autonomous Region of China during 2011–2014.The result reveals obvious uneven distributions of outage events for time and space due to the spatial and temporal variation of severe weather.Based on the results, an estimation method is proposed in this paper.Split and aggregation is used to smooth the outage and weather data.The poisson model is adopted in our method to investigate the statistic characteristics of transmission line outage events.Regression analysis is applied to obtain the correlation between the weather intensity and history failure rate.Furthermore the method proposed is validated against the empirical outage data.展开更多
Optical color filters are widely applied in many areas including display,imaging,sensing,holography,energy harvest,and measurement.Traditional dye-based color filters have drawbacks such as environmental hazards and i...Optical color filters are widely applied in many areas including display,imaging,sensing,holography,energy harvest,and measurement.Traditional dye-based color filters have drawbacks such as environmental hazards and instability under high temperature and ultraviolet radiation.With advances in nanotechnology,structural color filters,which are based on the interaction of light with designed nanostructures,are able to overcome the drawbacks.Also,it is possible to fabricate structural color filters using standard complementary metal-oxide-semiconductor(CMOS)fabrication facilities with low cost and high volume.In this work,metasurface-based subtractive color filters(SCFs)are demonstrated on 12-inch(300-mm)glass wafers using a CMOS-compatible fabrication process.In order to make the transmissive-type SCF on a transparent glass wafer,an in-house developed layer transfer process is used to solve the glass wafer handling issue in fabrication tools.Three different heights of embedded silicon nanopillars(110,170,and 230 nm)are found to support magnetic dipole resonances.With pillar height and pitch variation,SCFs with different displayed colors are achieved.Based on the resonance wavelength,the displayed color of the metasurface is verified within the red-yellow-blue color wheel.The simulation and measurement results are compared and discussed.The work provides an alternative design for high efficiency color filters on a CMOS-compatible platform,and paves the way towards mass-producible large-area metasurfaces.展开更多
Background: As one of the most common endocrinal disorders for women at childbearing age, the diagnostic criteria of polycystic ovary syndrome (PCOS) have been defined differently among different international health ...Background: As one of the most common endocrinal disorders for women at childbearing age, the diagnostic criteria of polycystic ovary syndrome (PCOS) have been defined differently among different international health organizations. Phenotypic heterogeneity of PCOS also brings about difficulties for its diagnosis and management assessment. Therefore, more efficient biomarkers representing the progression of PCOS are expected to be integrated into the monitoring of management process using metabolomic approaches.Methods: In this prospective randomized controlled trial, 117 PCOS patients were enrolled from December 2016 to September 2017. Classical diagnostic parameters, blood glucose, and metabolome were measured in these patients before and at 2 months and 3 months of different medical interventions. The receiver operating characteristic (ROC) curves were built based on multivariate statistical analysis using data at baseline and 3 months’ management, and combinational biomarkers with appreciable sensitivity and specificity were selected, which then validated with data collected at 2 months.Results: A set of metabolites including glutamic acid, aspartic acid, 1-methylnicotinamide, acetylcarnitine, glycerophosphocholine, and oleamide were filtered out with high performance in representing the improvement through 3-month management of PCOS with high sensitivity and specificity in ROC analysis and validation with other two groups showed an appreciable area under the curve over 0.96.Conclusions: The six metabolites were representative of the remission of PCOS through medical intervention, making them a set of potential biomarkers for assessing the outcome of PCOS management.Trial Registration: ClinicalTrials.gov, NCT03264638.展开更多
P-N and P=N bonds play important roles in the design and synthesis of functional molecules such as bioactive compounds and organic ligands for catalysis.Existing methods for P-N coupling mostly rely on Staudinger cond...P-N and P=N bonds play important roles in the design and synthesis of functional molecules such as bioactive compounds and organic ligands for catalysis.Existing methods for P-N coupling mostly rely on Staudinger condensation or nucleophilic substitution between phosphorus electrophiles and amine nucleo philes.Herein,we report a nitrene-mediated intermolecular P-N coupling reaction between various phos phorus nucleophiles and dioxazolones under simp le iron-catalyzed conditions.These reactions offer an efficient,versatile,and broadly applicable method for synthesis of a range of N-P compounds,including amidophosphines,iminophosphonamides,phosphinamides,aminophosphines,and iminophospho ranes,from readily available precursors under mild conditions.展开更多
基金supported by National NaturalScience Foundation of China (No.51307125)
文摘Estimation for weather-related failure probability of overhead transmission lines is essential in the reliability assessment of a power system.This paper analyzes the outage and weather data of 110 kV overhead transmission lines in the Guangxi Zhuang Autonomous Region of China during 2011–2014.The result reveals obvious uneven distributions of outage events for time and space due to the spatial and temporal variation of severe weather.Based on the results, an estimation method is proposed in this paper.Split and aggregation is used to smooth the outage and weather data.The poisson model is adopted in our method to investigate the statistic characteristics of transmission line outage events.Regression analysis is applied to obtain the correlation between the weather intensity and history failure rate.Furthermore the method proposed is validated against the empirical outage data.
基金Agency for Science,Technology and Research[RIE2020 Advanced Manufacturing and Engineering(AME),Programmatic Grant(A18A7b0058)]。
文摘Optical color filters are widely applied in many areas including display,imaging,sensing,holography,energy harvest,and measurement.Traditional dye-based color filters have drawbacks such as environmental hazards and instability under high temperature and ultraviolet radiation.With advances in nanotechnology,structural color filters,which are based on the interaction of light with designed nanostructures,are able to overcome the drawbacks.Also,it is possible to fabricate structural color filters using standard complementary metal-oxide-semiconductor(CMOS)fabrication facilities with low cost and high volume.In this work,metasurface-based subtractive color filters(SCFs)are demonstrated on 12-inch(300-mm)glass wafers using a CMOS-compatible fabrication process.In order to make the transmissive-type SCF on a transparent glass wafer,an in-house developed layer transfer process is used to solve the glass wafer handling issue in fabrication tools.Three different heights of embedded silicon nanopillars(110,170,and 230 nm)are found to support magnetic dipole resonances.With pillar height and pitch variation,SCFs with different displayed colors are achieved.Based on the resonance wavelength,the displayed color of the metasurface is verified within the red-yellow-blue color wheel.The simulation and measurement results are compared and discussed.The work provides an alternative design for high efficiency color filters on a CMOS-compatible platform,and paves the way towards mass-producible large-area metasurfaces.
文摘Background: As one of the most common endocrinal disorders for women at childbearing age, the diagnostic criteria of polycystic ovary syndrome (PCOS) have been defined differently among different international health organizations. Phenotypic heterogeneity of PCOS also brings about difficulties for its diagnosis and management assessment. Therefore, more efficient biomarkers representing the progression of PCOS are expected to be integrated into the monitoring of management process using metabolomic approaches.Methods: In this prospective randomized controlled trial, 117 PCOS patients were enrolled from December 2016 to September 2017. Classical diagnostic parameters, blood glucose, and metabolome were measured in these patients before and at 2 months and 3 months of different medical interventions. The receiver operating characteristic (ROC) curves were built based on multivariate statistical analysis using data at baseline and 3 months’ management, and combinational biomarkers with appreciable sensitivity and specificity were selected, which then validated with data collected at 2 months.Results: A set of metabolites including glutamic acid, aspartic acid, 1-methylnicotinamide, acetylcarnitine, glycerophosphocholine, and oleamide were filtered out with high performance in representing the improvement through 3-month management of PCOS with high sensitivity and specificity in ROC analysis and validation with other two groups showed an appreciable area under the curve over 0.96.Conclusions: The six metabolites were representative of the remission of PCOS through medical intervention, making them a set of potential biomarkers for assessing the outcome of PCOS management.Trial Registration: ClinicalTrials.gov, NCT03264638.
基金the Natural Science Foundation of China(nos.21421062 and 21901127)the China Postdoctoral Science Foundation(nos.2018M640225 and 2019T120179)Nankai-Cangzhou Green Chemistry Institute(no.NCC2020FH02)for financial support of this work.
文摘P-N and P=N bonds play important roles in the design and synthesis of functional molecules such as bioactive compounds and organic ligands for catalysis.Existing methods for P-N coupling mostly rely on Staudinger condensation or nucleophilic substitution between phosphorus electrophiles and amine nucleo philes.Herein,we report a nitrene-mediated intermolecular P-N coupling reaction between various phos phorus nucleophiles and dioxazolones under simp le iron-catalyzed conditions.These reactions offer an efficient,versatile,and broadly applicable method for synthesis of a range of N-P compounds,including amidophosphines,iminophosphonamides,phosphinamides,aminophosphines,and iminophospho ranes,from readily available precursors under mild conditions.
