BACKGROUND Studies have shown a strong bidirectional association between diabetes and depression,with diabetes increasing the risk of developing depression and vice versa.Depression among patients with diabetes is ass...BACKGROUND Studies have shown a strong bidirectional association between diabetes and depression,with diabetes increasing the risk of developing depression and vice versa.Depression among patients with diabetes is associated with poor glycemic control,complications,and poor self-care.AIM To explore the present state of research globally concerning diabetes and depression,to aid understanding the current research landscape and identify potential future areas of research.METHODS A bibliometric approach was used,utilizing the Scopus database to gather pertinent research articles released from 2004 to 2023.Analyses encompassed publication patterns,significant contributors,research focal points,prevalent themes,and the most influential articles,aimed at discerning emerging research subjects.RESULTS A total of 3229 publications that met the search criteria were identified.A significant increase in the number of publications related to diabetes and depression has been observed in the past two decades.The most productive nation was the USA(n=1015;31.43%),followed by China(n=325;10.07%),the UK(n=236;7.31%),and Germany(n=218;6.75%).Three principal themes in research on depression and diabetes were delineated by the analysis.First,the exploration of the elevated prevalence and etiology of this comorbidity;second,the focus on interventions,particularly randomized controlled trials,aimed at enhancing diabetes management among individuals with depression;and finally,the investigation of the involved risk factors and biological mechanisms under-lying this bidirectional relationship.CONCLUSION There has been a recent surge of interest in the relationship between diabetes and depression.This could aid researchers to identify areas lacking in the literature and shape future research.展开更多
BACKGROUND Depression is one of the most common and important psychological issues faced by dialysis patients.It can make it more difficult for them to adhere to their treatment regimen,which,in turn,can worsen their ...BACKGROUND Depression is one of the most common and important psychological issues faced by dialysis patients.It can make it more difficult for them to adhere to their treatment regimen,which,in turn,can worsen their physical symptoms and lead to poorer health outcomes.AIM To examine the evolution and growth of publications related to dialysis and depression.The objectives were to identify the number of publications,the top active countries,the contributed institutions,funding agencies and journals,as well as to perform citation and research theme analysis.METHODS The search was conducted using the Scopus database for publications related to dialysis and depression between 1970 and 2022.Subsequently,bibliometric analysis was carried out on the data obtained using VOSviewer software,version 1.6.9.This analysis included visualization analysis,co-occurrence analysis and examination of publication trends in dialysis and depression.RESULTS We identified 800 publications that met the search criteria.The number of publications related to dialysis and depression has increased significantly in the past two decades.The USA led the way with 144 publications,which is 18%of all publications on this topic.Turkey came second with 88 publications(11%),followed by China with 55 publications(6.88%)and Iran with 52 publications(6.5%).Analysis of the research theme identified three main clusters related to gender differences in prevalence,identification of depression as a risk factor,and effective interventions to relieve depression.Future research direction analysis shows a shift toward effective interventions to relieve depression in dialysis patients.CONCLUSION This study provides a comprehensive overview of growth,trends and research themes related to dialysis and depression that could help researchers identify gaps in the literature and develop future research.展开更多
BACKGROUND The gut microbiota plays a crucial role in gastrointestinal and overall health.Randomized clinical trials(RCTs)play a crucial role in advancing our knowledge and evaluating the efficacy of therapeutic inter...BACKGROUND The gut microbiota plays a crucial role in gastrointestinal and overall health.Randomized clinical trials(RCTs)play a crucial role in advancing our knowledge and evaluating the efficacy of therapeutic interventions targeting the gut microbiota.AIM To conduct a comprehensive bibliometric analysis of the literature on RCTs involving the gut microbiota.METHODS Using bibliometric tools,a descriptive cross-sectional investigation was conducted on scholarly publications concentrated on RCTs related to gut microbiota,spanning the years 2003 to 2022.The study used VOSviewer version 1.6.9 to examine collaboration networks between different countries and evaluate the frequently employed terms in the titles and abstracts of the retrieved publications.The primary objective of this analysis was to identify key research areas and focal points associated with RCTs involving the gut microbiota.RESULTS A total of 1061 relevant articles were identified from the 24758 research articles published between 2003 and 2022.The number of publications showed a notable increase over time,with a positive correlation(R2=0.978,P<0.001).China(n=276,26.01%),the United States(n=254,23.94%),and the United Kingdom(n=97,9.14%)were the leading contributing countries.Københavns Universitet(n=38,3.58%)and Dankook University(n=35,3.30%)were the top active institutions.The co-occurrence analysis shows current gut microbiota research trends and important topics,such as obesity interventions targeting the gut microbiota,the efficacy and safety of fecal microbiota transplantation,and the effects of dietary interventions on humans.CONCLUSION The study highlights the rapid growth and importance of research on RCTs that involve the gut microbiota.This study provides valuable insight into research trends,identifies key players,and outlines potential future directions in this field.Additionally,the co-occurrence analysis identified important topics that play a critical role in the advancement of science and provided insights into future research directions in this field.展开更多
BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic burdens.As it has been linked to insulin resistance(IR),this...BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic burdens.As it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and NAFLD.AIM To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and IR.METHODS This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the SciVerse Scopus database from 1999 to 2022.The search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and NAFLD.VOSviewer software was used to visualize research trends,collaborations,and key thematic areas.The analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited references.RESULTS This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and 2022.The search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)reviews.The most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflammatory and high-fat diet impacts on NAFLD”.CONCLUSION This is the first bibliometric analysis to examine the relationship between IR and NAFLD.In response to the escalating global health challenge of NAFLD,this research highlights an urgent need for a better understanding of this condition and for the development of intervention strategies.Policymakers need to prioritize and address the increasing prevalence of NAFLD.展开更多
BACKGROUND Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder. Dysregulation of the gut–brain axis plays a central role in the pathophysiology of IBS. It is increasingly clear that the mic...BACKGROUND Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder. Dysregulation of the gut–brain axis plays a central role in the pathophysiology of IBS. It is increasingly clear that the microbiome plays a key role in the development and normal functioning of the gut–brain axis.AIM To facilitate the identification of specific areas of focus that may be of relevance to future research. This study represents a bibliometric analysis of the literature pertaining to the microbiome in IBS to understand the development of this field.METHODS The data used in our bibliometric analysis were retrieved from the Scopus database. The terms related to IBS and microbiome were searched in titles or abstracts within the period of 2000–2019. VOSviewer software was used for data visualization.RESULTS A total of 13055 documents related to IBS were retrieved at the global level. There were 1872 scientific publications focused on the microbiome in IBS. There was a strong positive correlation between publication productivity related to IBS in all fields and productivity related to the microbiome in IBS(r = 0.951, P < 0.001). The United States was the most prolific country with 449(24%) publications, followed by the United Kingdom(n = 176, 9.4%), China(n = 154, 8.2%), and Italy(n = 151, 8.1%). The h-index for all retrieved publications related to the microbiome in IBS was 138. The hot topics were stratified into four clusters:(1) The gut–brain axis related to IBS;(2) Clinical trials related to IBS and the microbiome;(3) Drugmediated manipulation of the gut microbiome;and(4) The role of the altered composition of intestinal microbiota in IBS prevention.CONCLUSION This is the first study to evaluate and quantify global research productivity pertaining to the microbiome in IBS. The number of publications regarding the gut microbiota in IBS has continuously grown since 2013. This finding suggests that the future outlook for interventions targeting the gut microbiota in IBS remains promising.展开更多
BACKGROUND Coronavirus disease 2019(COVID-19)has affected daily life globally dramatically over the last year.The impact of the COVID-19 epidemic on mental health is expected to be immense and likely to be long-lastin...BACKGROUND Coronavirus disease 2019(COVID-19)has affected daily life globally dramatically over the last year.The impact of the COVID-19 epidemic on mental health is expected to be immense and likely to be long-lasting,raising a range of global problems that need to be addressed accordingly.AIM To analyze the Scopus-based depression research and COVID-19,explain the advancement of research nowadays,and comment on the possible hotspots of depression research and COVID-19 to obtain a more global perspective.METHODS In this report,bibliometric analysis and visualization are used to explain COVID-19's global research status on depression and provide researchers with a guide to identify future research directions.Relevant studies on depression and COVID-19 were retrieved from the Scopus database.Visualization maps were produced using the VOSviewer software,including research collaboration.RESULTS At the time of data collection(November 18,2020),77217 documents were released by Scopus to COVID-19 in all areas of research.By limiting the search to depression and COVID-19(January 2020 up until November 18,2020),there are 1274 published articles on depression and COVID-19 in the Scopus.The great majority of which are original articles(n=1049,82.34%),followed by 118 review articles(9.26%),66 letters(5.18%).The United States had the highest number of publications at 282(22.14%),followed by China(19.07%)at 243 and Italy at 121(9.5%).The major two clusters are signified by mental health outcomes among the general population and mental health outcomes among health care workers.CONCLUSION The evidence from this study found that many articles focused on mental health outcomes among the general population and health care workers.With adequate psychological support offered by the government or community agencies,mental health in various communities should be put within the local and global public health agenda.This changing situation involves the scientific community's collaborative efforts to contribute to population monitoring during quarantine and COVID-19 outbreaks and to examine the short-and long-term adverse effects on psychological well-being.展开更多
BACKGROUND One of the most popular bariatric procedures is sleeve gastrectomy,and it has become significantly more common in recent years.AIM To evaluate the research activity in sleeve gastrectomy over the last two d...BACKGROUND One of the most popular bariatric procedures is sleeve gastrectomy,and it has become significantly more common in recent years.AIM To evaluate the research activity in sleeve gastrectomy over the last two decades,and to visualize the hot spots and emerging trends in this type of bariatric surgeryusing bibliometric methods.METHODS The Scopus database was used to search for publications related to sleeve gastrectomy.The retrieved publications were reviewed in terms of year of publication,type of study,country of origin,institutions,journals,and citation patterns by using descriptive analysis.Collaboration network and term cooccurrence analysis were visualized by using VOSviewer software.RESULTS The search strategy yielded a total of 6508 publications on sleeve gastrectomy from 2001 to 2020.As regards the document type,the majority were articles(n=5230;80.36%),followed by reviews(n=544;8.36%).The top three countries are the United States,with 1983 publications(30.47%),followed by France(600;9.22%)and Italy(417;6.71%).The most cited publication was published in 2012 by Schauer et al in the New England Journal of Medicine(n=1435 citations).This publication found that weight loss was greater in the sleeve gastrectomy group than in the medical therapy group.Furthermore,this study demonstrated that 12 mo of medical therapy plus bariatric surgery greatly improved glycemic regulation in obese patients with uncontrolled type 2 diabetes compared with medical therapy alone.The focus of the current literature on sleeve gastrectomy was directed toward several themes such as morbidity and potential complications,the complexity of the procedure and different surgical approaches,and diabetes and body mass index in correlation to sleeve gastrectomy.CONCLUSION The number of sleeve gastrectomy publications has gradually grown over the last 20 years.This bibliometric analysis could help researchers better understand the knowledge base and research frontiers surrounding sleeve gastrectomy.In addition,future studies may focus on emerging research hotspots.展开更多
BACKGROUND Insulin resistance is a risk factor for metabolic syndromes and is associated with a wide variety of metabolic illnesses,including obesity,type 2 diabetes,and cardiovascular disease.AIM To investigate and m...BACKGROUND Insulin resistance is a risk factor for metabolic syndromes and is associated with a wide variety of metabolic illnesses,including obesity,type 2 diabetes,and cardiovascular disease.AIM To investigate and map global insulin resistance studies.METHODS A bibliometric methodology was applied to the literature retrieved from the Scopus database and Reference Citation Analysis(https://www.referencecitationanalysis.com)by using a validated search strategy.The study period was limited from 2002 to 2021.Bibliometric indicators and mapping were presented.RESULTS A total of 26808 articles on the topic of insulin resistance were included in the Scopus database.The articles included research articles(n=21918;81.76%),review articles(n=2641;9.85%),and letters(n=653;2.44%).During the study period,136 countries contributed to the research on insulin resistance.The highest number of articles was from the United States(n=7360;27.45%),followed by China(n=3713;13.85%),Japan(n=1730,6.45%),Italy(n=1545;5.54%),and the United Kingdom(n=1484;5.54%).The retrieved articles identified two main research themes:“inflammatory mechanisms in the regulation of insulin resistance”and“mechanisms linking obesity to insulin resistance”.CONCLUSION Our data show that insulin resistance has steadily gained interest from researchers,as evidenced by the number of citations and yearly publications.Publications have grown significantly in the last decade,while low-income countries with greater burdens continue to produce fewer publications in this field.This approach might assist researchers in choosing new research areas and recognizing research hotspots and frontiers.In the future,perhaps high-quality clinical evidence will be acquired.展开更多
BACKGROUND Nutrition is a significant modifiable element that influences the composition of the gastrointestinal microbiota,implying the possibility of therapeutic diet methods that manipulate the composition and dive...BACKGROUND Nutrition is a significant modifiable element that influences the composition of the gastrointestinal microbiota,implying the possibility of therapeutic diet methods that manipulate the composition and diversity of the microbial.AIM To overview research papers on nutrition and gut microbiota and determines the hotspots in this field at the global level.METHODS Scopus and Reference Citation Analysis were used to construct a bibliometric technique.It was decided to create bibliometric indicators and mapping as in most previous studies.2012 through 2021 served as the study's timeframe.RESULTS A total of 5378 documents from the Scopus database were selected for analysis.Of all retrieved studies,78.52%were research papers(n=4223),followed by reviews(n=820;15.25%).China ranked first with a total number of articles of 1634(30.38%),followed by the United States in second place with a total number of articles of 1307(24.3%).In the last decade,emerging hotspots for gut microbiota and nutrition research included"gut microbiota metabolism and interaction with dietary components","connection between the gut microbiota and weight gain",and"the influence of high-fat diet and gut microbiota on metabolic disorders".CONCLUSION This is the first thorough bibliometric analysis of nutrition and gut microbiota publications conducted on a global level.Investigation of the association between nutrition/diet and the gut microbiota is still in its infancy and will be expanded in the future.However,according to recent trends,the"effect of gut microbiota and high-fat diet on metabolic disorders"will be an increasing concern in the future.展开更多
BACKGROUND Recently,neonatal abstinence syndrome(NAS)emerged as a significant global concern with a dramatic increase in healthcare expenditures.The incidence of the NAS has increased notably in the past decade and em...BACKGROUND Recently,neonatal abstinence syndrome(NAS)emerged as a significant global concern with a dramatic increase in healthcare expenditures.The incidence of the NAS has increased notably in the past decade and emergence as a global public health problem.AIM To evaluate the development and trend of global NAS research from 1958 to 2019 by bibliometric analysis.METHODS Analyzed aspects included publication output per year,language,document types,journals,countries/territories,h-index,authors,and top research priorities.The VOSviewer was used to determine the top research priorities,and trends,and to present bibliometric networks concerning various dimensions,such as coauthorship,authors,and countries.RESULTS A total of 1738 articles were retrieved in the Scopus database from 1958 to 2019.It was found that the great majority of the total NAS documents(n=1295)were original articles followed by reviews(n=268)and letters(n=48).The most productive countries in the NAS field were the United States(n=833),Canada(n=112),the United Kingdom(n=111),and Germany(n=77).Treatment and hospital outcomes in NAS,evidence-based nurse-driven interventions for the care of newborns with NAS,and a systematic reviews and network meta-analysis for therapeutic approaches of NAS were found in recent years(after 2010),compared with terms such as pathophysiology,mechanisms of NAS,and signs and symptoms in the early years.CONCLUSION Treatment and pediatric outcomes and the effectiveness of pharmacological treatment may be frontiers in the NAS field,and continued efforts from researchers are needed in those topics.展开更多
BACKGROUND Cancer is a severe public health issue that seriously jeopardizes global health.In individuals with coronavirus disease 2019(COVID-19),cancer is considered an independent risk factor for severe illness and ...BACKGROUND Cancer is a severe public health issue that seriously jeopardizes global health.In individuals with coronavirus disease 2019(COVID-19),cancer is considered an independent risk factor for severe illness and increased mortality.AIM To identify research hotspots and prospects,we used bibliometrics to examine the global production of COVID-19 literature published in the field of oncology.METHODS Data on publication output were identified based on the Scopus database between January 1,2020,and June 21,2022.This study used VOSviewer to analyze collaboration networks among countries and assess the terms most often used in the titles and abstracts of retrieved publications to determine research hotspots linked to cancer and COVID-19.The Impact Index Per Article for the top 10 high-cited papers collected from Reference Citation Analysis(RCA)are presented.RESULTS A total of 7015 publications were retrieved from the database.The United States published the greatest number of articles(2025;28.87%),followed by Italy(964;13.74%),the United Kingdom(839;11.96%),and China(538;7.67%).The University of Texas MD Anderson Cancer Center(n=205,2.92%)ranked first,followed by the Memorial Sloan-Kettering Cancer Center(n=176,2.51%).The European Journal of Cancer(n=106,1.51%)ranked first,followed by the Frontiers in Oncology(n=104,1.48%),Cancers(n=102,1.45%),and Pediatric Blood and Cancer(n=95;1.35%).The hot topics were stratified into“cancer care management during the COVID-19 pandemic”;and“COVID-19 vaccines in cancer patients”.CONCLUSION This is the first bibliometric analysis to determine the present state and upcoming hot themes related to cancer and COVID-19 and vice versa using VOSviewer during the early stages of the pandemic.The emergence of hot themes related to cancer and COVID-19 may aid researchers in identifying new research areas in this field.展开更多
BACKGROUND Binge-eating disorder(BED)is a clinical syndrome and is considered the most common type of eating disorder.However,our understanding of the global performance and progress of BED research is limited.AIM To ...BACKGROUND Binge-eating disorder(BED)is a clinical syndrome and is considered the most common type of eating disorder.However,our understanding of the global performance and progress of BED research is limited.AIM To describe and perform a bibliometric analysis of the state of BED research.METHODS The term‘Binge eating’was searched in the title throughout the previous year’s up to December 31,2020.We searched the Scopus and Reference Citation Analysis for publications on Binge eating.The VOSviewer software version 1.6.17 was used to produce the network visualization map of the most frequent author,collaborative relationships between countries/regions,and to determine the hotspots related to binge eating research.In addition,conventional bibliometric indicators were generated.RESULTS The search strategy found 2713 total articles and an average of 62 articles per year.Among them,‘Article’represented 82.49%of the publications(n=2238 articles)and was the most frequent type,followed by reviews(n=243;8.96%).The number of publications increased steadily during the last decade of the study period.One hundred and thirty-two countries contributed to binge eating research,with 1495(55.11%)articles published in the United States,followed by Italy with 256(9.44%),the United Kingdom with 183(6.75%),and Germany with 182(6.71%).Currently,the main hot topics related to BED are‘type of treatment and management and treatment provided to BED”;“processes and pathways to binge eating”;and‘diagnosis,signs and symptoms,comorbidities and prevalence and associated factors with BED’.CONCLUSION The number of publications has increased noticeably during the previous decade.There are indeed relatively few publications on BED from low-and middle-income nations,so much is to be learned from the experience of all countries.Studies on this topic are critical in all countries to discover risk factors and effective intervention measures.Although our findings are preliminary,they imply that the future prospects for interventions aimed at BED management are bright,focusing on complex models of care and long-term maintenance of therapeutic gains.展开更多
BACKGROUND Coronavirus disease 2019(COVID-19)is a global pandemic that can cause diarrhoea,nausea/vomiting,and abdominal pain,among other gastrointestinal(GI)symptoms.AIM To perform a bibliometric analysis of the glob...BACKGROUND Coronavirus disease 2019(COVID-19)is a global pandemic that can cause diarrhoea,nausea/vomiting,and abdominal pain,among other gastrointestinal(GI)symptoms.AIM To perform a bibliometric analysis of the global research production pertaining to GI involvement in COVID-19.METHODS The Scopus database was used to search the global literature on GI involvement in COVID-19 during 2020.A bibliometric review of these publications was also performed using VOSviewer.RESULTS Scopus had published 95615 documents on COVID-19 in all areas of research at the time of data collection.In total,1267 publications on the topic of GI and COVID-19 were identified.Research articles(n=606;47.83%),letters(293;23.13%),and reviews(186;14.68%)were the most popular types of documents.The most productive countries and institutions in this field were the United States and Huazhong University of Science and Technology.The most cited paper was Xiao et al,which was published in Gastroenterology as a brief communication,with 798 citations.This paper provides evidence for GI infection of COVID-19 and its possible faecal–oral transmission route.In the term cluster analysis,there were two frontiers in this field:GI manifestations among COVID-19 patients and the implications of COVID-19 for the gastroenterologist.CONCLUSION GI manifestations among COVID-19 patients and implications of COVID-19 for gastroenterologists were of interest,especially in the early stages of the pandemic.展开更多
Background:To meet the future challenges of infectious diseases and limit the spread of multidrug resistant microorganisms,a better understanding of published studies in the field of infectious diseases is needed.The ...Background:To meet the future challenges of infectious diseases and limit the spread of multidrug resistant microorganisms,a better understanding of published studies in the field of infectious diseases is needed.The objective of this study was to analyze the quantity and quality of research activity in the field of infectious diseases in Arab countries and compare it with that in non-Arab countries.Methods:Documents published in Arab countries within the research category of“infectious diseases”were extracted and analyzed using the Web of Science database.The data analyzed represent research productivity during the time interval between 1900–2012.Results:Worldwide,the total number of documents published in the field of infectious diseases up to 2012 was 227,188.A total of 2,408 documents in the field of infectious diseases were published in Arab countries,which represents 1.06%of worldwide research output.Research output from Arab countries in the field of infectious diseases was low for decades.However,approximately a five-fold increase was observed in the past decade.Arab countries ranked 56th to 218th on the standard competition ranking(SCR)in worldwide publications in the field of infectious diseases.Egypt,with a total publication of 464(19.27%)documents ranked first among Arab countries,while Kuwait University was the most productive institution with a total of 158(6.56%)documents.Average citation per document published in Arab countries was 13.25 and the h-index was 64.Tuberculosis(230;9.55%),malaria(223;9.26%),and hepatitis(189;7.8%)were the top three infectious diseases studied as according to the retrieved documents.Conclusion:The present data reveals that some Arab countries contribute significantly to the field of infectious diseases.However,Arab countries need to work harder to bridge the gap in this field.Compared with non-Arab countries in the Middle East,research output from Arab countries was high,but more efforts are needed to enhance the quality of this output.Future research in the field should be encouraged and correctly directed.展开更多
文摘BACKGROUND Studies have shown a strong bidirectional association between diabetes and depression,with diabetes increasing the risk of developing depression and vice versa.Depression among patients with diabetes is associated with poor glycemic control,complications,and poor self-care.AIM To explore the present state of research globally concerning diabetes and depression,to aid understanding the current research landscape and identify potential future areas of research.METHODS A bibliometric approach was used,utilizing the Scopus database to gather pertinent research articles released from 2004 to 2023.Analyses encompassed publication patterns,significant contributors,research focal points,prevalent themes,and the most influential articles,aimed at discerning emerging research subjects.RESULTS A total of 3229 publications that met the search criteria were identified.A significant increase in the number of publications related to diabetes and depression has been observed in the past two decades.The most productive nation was the USA(n=1015;31.43%),followed by China(n=325;10.07%),the UK(n=236;7.31%),and Germany(n=218;6.75%).Three principal themes in research on depression and diabetes were delineated by the analysis.First,the exploration of the elevated prevalence and etiology of this comorbidity;second,the focus on interventions,particularly randomized controlled trials,aimed at enhancing diabetes management among individuals with depression;and finally,the investigation of the involved risk factors and biological mechanisms under-lying this bidirectional relationship.CONCLUSION There has been a recent surge of interest in the relationship between diabetes and depression.This could aid researchers to identify areas lacking in the literature and shape future research.
文摘BACKGROUND Depression is one of the most common and important psychological issues faced by dialysis patients.It can make it more difficult for them to adhere to their treatment regimen,which,in turn,can worsen their physical symptoms and lead to poorer health outcomes.AIM To examine the evolution and growth of publications related to dialysis and depression.The objectives were to identify the number of publications,the top active countries,the contributed institutions,funding agencies and journals,as well as to perform citation and research theme analysis.METHODS The search was conducted using the Scopus database for publications related to dialysis and depression between 1970 and 2022.Subsequently,bibliometric analysis was carried out on the data obtained using VOSviewer software,version 1.6.9.This analysis included visualization analysis,co-occurrence analysis and examination of publication trends in dialysis and depression.RESULTS We identified 800 publications that met the search criteria.The number of publications related to dialysis and depression has increased significantly in the past two decades.The USA led the way with 144 publications,which is 18%of all publications on this topic.Turkey came second with 88 publications(11%),followed by China with 55 publications(6.88%)and Iran with 52 publications(6.5%).Analysis of the research theme identified three main clusters related to gender differences in prevalence,identification of depression as a risk factor,and effective interventions to relieve depression.Future research direction analysis shows a shift toward effective interventions to relieve depression in dialysis patients.CONCLUSION This study provides a comprehensive overview of growth,trends and research themes related to dialysis and depression that could help researchers identify gaps in the literature and develop future research.
文摘BACKGROUND The gut microbiota plays a crucial role in gastrointestinal and overall health.Randomized clinical trials(RCTs)play a crucial role in advancing our knowledge and evaluating the efficacy of therapeutic interventions targeting the gut microbiota.AIM To conduct a comprehensive bibliometric analysis of the literature on RCTs involving the gut microbiota.METHODS Using bibliometric tools,a descriptive cross-sectional investigation was conducted on scholarly publications concentrated on RCTs related to gut microbiota,spanning the years 2003 to 2022.The study used VOSviewer version 1.6.9 to examine collaboration networks between different countries and evaluate the frequently employed terms in the titles and abstracts of the retrieved publications.The primary objective of this analysis was to identify key research areas and focal points associated with RCTs involving the gut microbiota.RESULTS A total of 1061 relevant articles were identified from the 24758 research articles published between 2003 and 2022.The number of publications showed a notable increase over time,with a positive correlation(R2=0.978,P<0.001).China(n=276,26.01%),the United States(n=254,23.94%),and the United Kingdom(n=97,9.14%)were the leading contributing countries.Københavns Universitet(n=38,3.58%)and Dankook University(n=35,3.30%)were the top active institutions.The co-occurrence analysis shows current gut microbiota research trends and important topics,such as obesity interventions targeting the gut microbiota,the efficacy and safety of fecal microbiota transplantation,and the effects of dietary interventions on humans.CONCLUSION The study highlights the rapid growth and importance of research on RCTs that involve the gut microbiota.This study provides valuable insight into research trends,identifies key players,and outlines potential future directions in this field.Additionally,the co-occurrence analysis identified important topics that play a critical role in the advancement of science and provided insights into future research directions in this field.
文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic burdens.As it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and NAFLD.AIM To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and IR.METHODS This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the SciVerse Scopus database from 1999 to 2022.The search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and NAFLD.VOSviewer software was used to visualize research trends,collaborations,and key thematic areas.The analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited references.RESULTS This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and 2022.The search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)reviews.The most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflammatory and high-fat diet impacts on NAFLD”.CONCLUSION This is the first bibliometric analysis to examine the relationship between IR and NAFLD.In response to the escalating global health challenge of NAFLD,this research highlights an urgent need for a better understanding of this condition and for the development of intervention strategies.Policymakers need to prioritize and address the increasing prevalence of NAFLD.
文摘BACKGROUND Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder. Dysregulation of the gut–brain axis plays a central role in the pathophysiology of IBS. It is increasingly clear that the microbiome plays a key role in the development and normal functioning of the gut–brain axis.AIM To facilitate the identification of specific areas of focus that may be of relevance to future research. This study represents a bibliometric analysis of the literature pertaining to the microbiome in IBS to understand the development of this field.METHODS The data used in our bibliometric analysis were retrieved from the Scopus database. The terms related to IBS and microbiome were searched in titles or abstracts within the period of 2000–2019. VOSviewer software was used for data visualization.RESULTS A total of 13055 documents related to IBS were retrieved at the global level. There were 1872 scientific publications focused on the microbiome in IBS. There was a strong positive correlation between publication productivity related to IBS in all fields and productivity related to the microbiome in IBS(r = 0.951, P < 0.001). The United States was the most prolific country with 449(24%) publications, followed by the United Kingdom(n = 176, 9.4%), China(n = 154, 8.2%), and Italy(n = 151, 8.1%). The h-index for all retrieved publications related to the microbiome in IBS was 138. The hot topics were stratified into four clusters:(1) The gut–brain axis related to IBS;(2) Clinical trials related to IBS and the microbiome;(3) Drugmediated manipulation of the gut microbiome;and(4) The role of the altered composition of intestinal microbiota in IBS prevention.CONCLUSION This is the first study to evaluate and quantify global research productivity pertaining to the microbiome in IBS. The number of publications regarding the gut microbiota in IBS has continuously grown since 2013. This finding suggests that the future outlook for interventions targeting the gut microbiota in IBS remains promising.
文摘BACKGROUND Coronavirus disease 2019(COVID-19)has affected daily life globally dramatically over the last year.The impact of the COVID-19 epidemic on mental health is expected to be immense and likely to be long-lasting,raising a range of global problems that need to be addressed accordingly.AIM To analyze the Scopus-based depression research and COVID-19,explain the advancement of research nowadays,and comment on the possible hotspots of depression research and COVID-19 to obtain a more global perspective.METHODS In this report,bibliometric analysis and visualization are used to explain COVID-19's global research status on depression and provide researchers with a guide to identify future research directions.Relevant studies on depression and COVID-19 were retrieved from the Scopus database.Visualization maps were produced using the VOSviewer software,including research collaboration.RESULTS At the time of data collection(November 18,2020),77217 documents were released by Scopus to COVID-19 in all areas of research.By limiting the search to depression and COVID-19(January 2020 up until November 18,2020),there are 1274 published articles on depression and COVID-19 in the Scopus.The great majority of which are original articles(n=1049,82.34%),followed by 118 review articles(9.26%),66 letters(5.18%).The United States had the highest number of publications at 282(22.14%),followed by China(19.07%)at 243 and Italy at 121(9.5%).The major two clusters are signified by mental health outcomes among the general population and mental health outcomes among health care workers.CONCLUSION The evidence from this study found that many articles focused on mental health outcomes among the general population and health care workers.With adequate psychological support offered by the government or community agencies,mental health in various communities should be put within the local and global public health agenda.This changing situation involves the scientific community's collaborative efforts to contribute to population monitoring during quarantine and COVID-19 outbreaks and to examine the short-and long-term adverse effects on psychological well-being.
文摘BACKGROUND One of the most popular bariatric procedures is sleeve gastrectomy,and it has become significantly more common in recent years.AIM To evaluate the research activity in sleeve gastrectomy over the last two decades,and to visualize the hot spots and emerging trends in this type of bariatric surgeryusing bibliometric methods.METHODS The Scopus database was used to search for publications related to sleeve gastrectomy.The retrieved publications were reviewed in terms of year of publication,type of study,country of origin,institutions,journals,and citation patterns by using descriptive analysis.Collaboration network and term cooccurrence analysis were visualized by using VOSviewer software.RESULTS The search strategy yielded a total of 6508 publications on sleeve gastrectomy from 2001 to 2020.As regards the document type,the majority were articles(n=5230;80.36%),followed by reviews(n=544;8.36%).The top three countries are the United States,with 1983 publications(30.47%),followed by France(600;9.22%)and Italy(417;6.71%).The most cited publication was published in 2012 by Schauer et al in the New England Journal of Medicine(n=1435 citations).This publication found that weight loss was greater in the sleeve gastrectomy group than in the medical therapy group.Furthermore,this study demonstrated that 12 mo of medical therapy plus bariatric surgery greatly improved glycemic regulation in obese patients with uncontrolled type 2 diabetes compared with medical therapy alone.The focus of the current literature on sleeve gastrectomy was directed toward several themes such as morbidity and potential complications,the complexity of the procedure and different surgical approaches,and diabetes and body mass index in correlation to sleeve gastrectomy.CONCLUSION The number of sleeve gastrectomy publications has gradually grown over the last 20 years.This bibliometric analysis could help researchers better understand the knowledge base and research frontiers surrounding sleeve gastrectomy.In addition,future studies may focus on emerging research hotspots.
文摘BACKGROUND Insulin resistance is a risk factor for metabolic syndromes and is associated with a wide variety of metabolic illnesses,including obesity,type 2 diabetes,and cardiovascular disease.AIM To investigate and map global insulin resistance studies.METHODS A bibliometric methodology was applied to the literature retrieved from the Scopus database and Reference Citation Analysis(https://www.referencecitationanalysis.com)by using a validated search strategy.The study period was limited from 2002 to 2021.Bibliometric indicators and mapping were presented.RESULTS A total of 26808 articles on the topic of insulin resistance were included in the Scopus database.The articles included research articles(n=21918;81.76%),review articles(n=2641;9.85%),and letters(n=653;2.44%).During the study period,136 countries contributed to the research on insulin resistance.The highest number of articles was from the United States(n=7360;27.45%),followed by China(n=3713;13.85%),Japan(n=1730,6.45%),Italy(n=1545;5.54%),and the United Kingdom(n=1484;5.54%).The retrieved articles identified two main research themes:“inflammatory mechanisms in the regulation of insulin resistance”and“mechanisms linking obesity to insulin resistance”.CONCLUSION Our data show that insulin resistance has steadily gained interest from researchers,as evidenced by the number of citations and yearly publications.Publications have grown significantly in the last decade,while low-income countries with greater burdens continue to produce fewer publications in this field.This approach might assist researchers in choosing new research areas and recognizing research hotspots and frontiers.In the future,perhaps high-quality clinical evidence will be acquired.
文摘BACKGROUND Nutrition is a significant modifiable element that influences the composition of the gastrointestinal microbiota,implying the possibility of therapeutic diet methods that manipulate the composition and diversity of the microbial.AIM To overview research papers on nutrition and gut microbiota and determines the hotspots in this field at the global level.METHODS Scopus and Reference Citation Analysis were used to construct a bibliometric technique.It was decided to create bibliometric indicators and mapping as in most previous studies.2012 through 2021 served as the study's timeframe.RESULTS A total of 5378 documents from the Scopus database were selected for analysis.Of all retrieved studies,78.52%were research papers(n=4223),followed by reviews(n=820;15.25%).China ranked first with a total number of articles of 1634(30.38%),followed by the United States in second place with a total number of articles of 1307(24.3%).In the last decade,emerging hotspots for gut microbiota and nutrition research included"gut microbiota metabolism and interaction with dietary components","connection between the gut microbiota and weight gain",and"the influence of high-fat diet and gut microbiota on metabolic disorders".CONCLUSION This is the first thorough bibliometric analysis of nutrition and gut microbiota publications conducted on a global level.Investigation of the association between nutrition/diet and the gut microbiota is still in its infancy and will be expanded in the future.However,according to recent trends,the"effect of gut microbiota and high-fat diet on metabolic disorders"will be an increasing concern in the future.
文摘BACKGROUND Recently,neonatal abstinence syndrome(NAS)emerged as a significant global concern with a dramatic increase in healthcare expenditures.The incidence of the NAS has increased notably in the past decade and emergence as a global public health problem.AIM To evaluate the development and trend of global NAS research from 1958 to 2019 by bibliometric analysis.METHODS Analyzed aspects included publication output per year,language,document types,journals,countries/territories,h-index,authors,and top research priorities.The VOSviewer was used to determine the top research priorities,and trends,and to present bibliometric networks concerning various dimensions,such as coauthorship,authors,and countries.RESULTS A total of 1738 articles were retrieved in the Scopus database from 1958 to 2019.It was found that the great majority of the total NAS documents(n=1295)were original articles followed by reviews(n=268)and letters(n=48).The most productive countries in the NAS field were the United States(n=833),Canada(n=112),the United Kingdom(n=111),and Germany(n=77).Treatment and hospital outcomes in NAS,evidence-based nurse-driven interventions for the care of newborns with NAS,and a systematic reviews and network meta-analysis for therapeutic approaches of NAS were found in recent years(after 2010),compared with terms such as pathophysiology,mechanisms of NAS,and signs and symptoms in the early years.CONCLUSION Treatment and pediatric outcomes and the effectiveness of pharmacological treatment may be frontiers in the NAS field,and continued efforts from researchers are needed in those topics.
文摘BACKGROUND Cancer is a severe public health issue that seriously jeopardizes global health.In individuals with coronavirus disease 2019(COVID-19),cancer is considered an independent risk factor for severe illness and increased mortality.AIM To identify research hotspots and prospects,we used bibliometrics to examine the global production of COVID-19 literature published in the field of oncology.METHODS Data on publication output were identified based on the Scopus database between January 1,2020,and June 21,2022.This study used VOSviewer to analyze collaboration networks among countries and assess the terms most often used in the titles and abstracts of retrieved publications to determine research hotspots linked to cancer and COVID-19.The Impact Index Per Article for the top 10 high-cited papers collected from Reference Citation Analysis(RCA)are presented.RESULTS A total of 7015 publications were retrieved from the database.The United States published the greatest number of articles(2025;28.87%),followed by Italy(964;13.74%),the United Kingdom(839;11.96%),and China(538;7.67%).The University of Texas MD Anderson Cancer Center(n=205,2.92%)ranked first,followed by the Memorial Sloan-Kettering Cancer Center(n=176,2.51%).The European Journal of Cancer(n=106,1.51%)ranked first,followed by the Frontiers in Oncology(n=104,1.48%),Cancers(n=102,1.45%),and Pediatric Blood and Cancer(n=95;1.35%).The hot topics were stratified into“cancer care management during the COVID-19 pandemic”;and“COVID-19 vaccines in cancer patients”.CONCLUSION This is the first bibliometric analysis to determine the present state and upcoming hot themes related to cancer and COVID-19 and vice versa using VOSviewer during the early stages of the pandemic.The emergence of hot themes related to cancer and COVID-19 may aid researchers in identifying new research areas in this field.
文摘BACKGROUND Binge-eating disorder(BED)is a clinical syndrome and is considered the most common type of eating disorder.However,our understanding of the global performance and progress of BED research is limited.AIM To describe and perform a bibliometric analysis of the state of BED research.METHODS The term‘Binge eating’was searched in the title throughout the previous year’s up to December 31,2020.We searched the Scopus and Reference Citation Analysis for publications on Binge eating.The VOSviewer software version 1.6.17 was used to produce the network visualization map of the most frequent author,collaborative relationships between countries/regions,and to determine the hotspots related to binge eating research.In addition,conventional bibliometric indicators were generated.RESULTS The search strategy found 2713 total articles and an average of 62 articles per year.Among them,‘Article’represented 82.49%of the publications(n=2238 articles)and was the most frequent type,followed by reviews(n=243;8.96%).The number of publications increased steadily during the last decade of the study period.One hundred and thirty-two countries contributed to binge eating research,with 1495(55.11%)articles published in the United States,followed by Italy with 256(9.44%),the United Kingdom with 183(6.75%),and Germany with 182(6.71%).Currently,the main hot topics related to BED are‘type of treatment and management and treatment provided to BED”;“processes and pathways to binge eating”;and‘diagnosis,signs and symptoms,comorbidities and prevalence and associated factors with BED’.CONCLUSION The number of publications has increased noticeably during the previous decade.There are indeed relatively few publications on BED from low-and middle-income nations,so much is to be learned from the experience of all countries.Studies on this topic are critical in all countries to discover risk factors and effective intervention measures.Although our findings are preliminary,they imply that the future prospects for interventions aimed at BED management are bright,focusing on complex models of care and long-term maintenance of therapeutic gains.
文摘BACKGROUND Coronavirus disease 2019(COVID-19)is a global pandemic that can cause diarrhoea,nausea/vomiting,and abdominal pain,among other gastrointestinal(GI)symptoms.AIM To perform a bibliometric analysis of the global research production pertaining to GI involvement in COVID-19.METHODS The Scopus database was used to search the global literature on GI involvement in COVID-19 during 2020.A bibliometric review of these publications was also performed using VOSviewer.RESULTS Scopus had published 95615 documents on COVID-19 in all areas of research at the time of data collection.In total,1267 publications on the topic of GI and COVID-19 were identified.Research articles(n=606;47.83%),letters(293;23.13%),and reviews(186;14.68%)were the most popular types of documents.The most productive countries and institutions in this field were the United States and Huazhong University of Science and Technology.The most cited paper was Xiao et al,which was published in Gastroenterology as a brief communication,with 798 citations.This paper provides evidence for GI infection of COVID-19 and its possible faecal–oral transmission route.In the term cluster analysis,there were two frontiers in this field:GI manifestations among COVID-19 patients and the implications of COVID-19 for the gastroenterologist.CONCLUSION GI manifestations among COVID-19 patients and implications of COVID-19 for gastroenterologists were of interest,especially in the early stages of the pandemic.
文摘Background:To meet the future challenges of infectious diseases and limit the spread of multidrug resistant microorganisms,a better understanding of published studies in the field of infectious diseases is needed.The objective of this study was to analyze the quantity and quality of research activity in the field of infectious diseases in Arab countries and compare it with that in non-Arab countries.Methods:Documents published in Arab countries within the research category of“infectious diseases”were extracted and analyzed using the Web of Science database.The data analyzed represent research productivity during the time interval between 1900–2012.Results:Worldwide,the total number of documents published in the field of infectious diseases up to 2012 was 227,188.A total of 2,408 documents in the field of infectious diseases were published in Arab countries,which represents 1.06%of worldwide research output.Research output from Arab countries in the field of infectious diseases was low for decades.However,approximately a five-fold increase was observed in the past decade.Arab countries ranked 56th to 218th on the standard competition ranking(SCR)in worldwide publications in the field of infectious diseases.Egypt,with a total publication of 464(19.27%)documents ranked first among Arab countries,while Kuwait University was the most productive institution with a total of 158(6.56%)documents.Average citation per document published in Arab countries was 13.25 and the h-index was 64.Tuberculosis(230;9.55%),malaria(223;9.26%),and hepatitis(189;7.8%)were the top three infectious diseases studied as according to the retrieved documents.Conclusion:The present data reveals that some Arab countries contribute significantly to the field of infectious diseases.However,Arab countries need to work harder to bridge the gap in this field.Compared with non-Arab countries in the Middle East,research output from Arab countries was high,but more efforts are needed to enhance the quality of this output.Future research in the field should be encouraged and correctly directed.
