BACKGROUND:The study aimed to compare the therapeutic effect of recombinant tissue plasminogen activator(rt-PA) on the onset of acute cerebral infarction(ACI) at different time points of the first 6 hours.METHODS:A re...BACKGROUND:The study aimed to compare the therapeutic effect of recombinant tissue plasminogen activator(rt-PA) on the onset of acute cerebral infarction(ACI) at different time points of the first 6 hours.METHODS:A retrospective analysis was conducted in 74 patients who received rt-PA thrombolysis treatment within 4.5 hours after ACI and another 15 patients who received rt-PA thrombolysis treatment between 4.5-6 hours after ACI.RESULTS:National Institute of Health Stroke Scale(NIHSS) scores were statistically decreased in both groups(P>0.05) at 24 hours and 7 days after ACI.There was no significant difference in modified ranking scores and mortality at 90 days after the treatment between the two groups(P>0.05).CONCLUSIONS:The therapeutic effect and mortality of rt-PA treatment in patients with ACI between 4.5-6 hours after the onset of the disease were similar to those in patients who received rtPA within 4.5 hours after the onset of this disease.Therefore,intravenous thrombolytic therapy for ACI within 4.5-6 hours after ACI was effective and safe.展开更多
This study examined the moderating effects of parent-child,same-sex,opposite-sex and teacher-student relation-ships between sibling status and loneliness during COVID-19.A total of 1,591 adolescents in China completed...This study examined the moderating effects of parent-child,same-sex,opposite-sex and teacher-student relation-ships between sibling status and loneliness during COVID-19.A total of 1,591 adolescents in China completed the study questionnaires which assessed the aforementioned variables.The results showed that same-sex and teacher-student relationships moderated the association between sibling status and loneliness.The results indicated that among participants with good same-sex relationships during COVID-19,compared to non-only-children parti-cipants,the only-children participants were more likely to experience a lower level of loneliness.However,parti-cipants with poor same-sex relationships experienced similar level of loneliness regardless of whether they had siblings.Thesefindings would be helpful for parents,teachers,and other stakeholders to take effective measures to reduce loneliness feelings among Chinese adolescents.展开更多
An individual’s perception,attitude,feeling and behavior about their body are important factors for mental health(depression).This study aims to explore the impact of body investment on depression,and the role of sel...An individual’s perception,attitude,feeling and behavior about their body are important factors for mental health(depression).This study aims to explore the impact of body investment on depression,and the role of self-efficacy and self-esteem in this connection.A hypothetical model about the relationship between body investment,selfefficacy,self-esteem and depression was tested.Using convenient sampling methods,a self-rated cross-sectional survey comprised of paper-based and online modes was conducted among 1,164 college students in Yunnan Province,China from July 2021 to August 2021.The data collection used the body investment scale,self-efficacy scale,self-esteem scale and depression scale.The results show that there is a low to moderate positive correlation(ranging between-0.11 and-0.59)between the research variables.The body investment of college students has a negative predictive effect(B=16.23,SE=0.65)on depression.This connection is also regulated by the mediating role of self-esteem and self-efficacy.All these factors explain 37.83%variability of research participation.These findings show how body investment affects the depressive state of college students.Further,these results help to demonstrate that self-efficacy and self-esteem are academically important for optimizing students’depression,so as to promote a good mental state.展开更多
基金supported by a grant from Shanghai Municipal Health Bureau(GWDTR201219)
文摘BACKGROUND:The study aimed to compare the therapeutic effect of recombinant tissue plasminogen activator(rt-PA) on the onset of acute cerebral infarction(ACI) at different time points of the first 6 hours.METHODS:A retrospective analysis was conducted in 74 patients who received rt-PA thrombolysis treatment within 4.5 hours after ACI and another 15 patients who received rt-PA thrombolysis treatment between 4.5-6 hours after ACI.RESULTS:National Institute of Health Stroke Scale(NIHSS) scores were statistically decreased in both groups(P>0.05) at 24 hours and 7 days after ACI.There was no significant difference in modified ranking scores and mortality at 90 days after the treatment between the two groups(P>0.05).CONCLUSIONS:The therapeutic effect and mortality of rt-PA treatment in patients with ACI between 4.5-6 hours after the onset of the disease were similar to those in patients who received rtPA within 4.5 hours after the onset of this disease.Therefore,intravenous thrombolytic therapy for ACI within 4.5-6 hours after ACI was effective and safe.
基金supported by Key Laboratory of Ethnic Languages and Information Technology of Ministry of Education of China,Northwest Minzu University,Lanzhou,Gansu,730030,China(KFKT202013,KFKT202016,KFKT202012,and 1001161310)The Young Doctor Foundation of Higher Education in Gansu Province“Research on the educational effect mechanism of the socialist core value‘unity of knowing and doing’of college students for nationalities in the new era”(No.2021QB-071)The 14th Five-Year Planning Project of Education Science in Gansu Province 2021“A study on the core behavior of patriotism of children in the new era”.Fundamental Research Funds for the Central Universities“Research on influencing factors of online education in post-epidemic era”(No.31920210125).
文摘This study examined the moderating effects of parent-child,same-sex,opposite-sex and teacher-student relation-ships between sibling status and loneliness during COVID-19.A total of 1,591 adolescents in China completed the study questionnaires which assessed the aforementioned variables.The results showed that same-sex and teacher-student relationships moderated the association between sibling status and loneliness.The results indicated that among participants with good same-sex relationships during COVID-19,compared to non-only-children parti-cipants,the only-children participants were more likely to experience a lower level of loneliness.However,parti-cipants with poor same-sex relationships experienced similar level of loneliness regardless of whether they had siblings.Thesefindings would be helpful for parents,teachers,and other stakeholders to take effective measures to reduce loneliness feelings among Chinese adolescents.
基金supported by Yunnan Provincial Philosophy and Social Science Planning Youth Project under Grant No.QN2018055the Young Doctor Foundation of Higher Education in Gansu Province(No.2021QB-071)the 14th five-year Planning project of Education science in Gansu Province 2021“A study on the core behavior of patriotism of children in the new era”.
文摘An individual’s perception,attitude,feeling and behavior about their body are important factors for mental health(depression).This study aims to explore the impact of body investment on depression,and the role of self-efficacy and self-esteem in this connection.A hypothetical model about the relationship between body investment,selfefficacy,self-esteem and depression was tested.Using convenient sampling methods,a self-rated cross-sectional survey comprised of paper-based and online modes was conducted among 1,164 college students in Yunnan Province,China from July 2021 to August 2021.The data collection used the body investment scale,self-efficacy scale,self-esteem scale and depression scale.The results show that there is a low to moderate positive correlation(ranging between-0.11 and-0.59)between the research variables.The body investment of college students has a negative predictive effect(B=16.23,SE=0.65)on depression.This connection is also regulated by the mediating role of self-esteem and self-efficacy.All these factors explain 37.83%variability of research participation.These findings show how body investment affects the depressive state of college students.Further,these results help to demonstrate that self-efficacy and self-esteem are academically important for optimizing students’depression,so as to promote a good mental state.
