Surface-enhanced Raman scattering(SERS)has been widely used in various fields due to high sensitivity,but it is hindered by its low repeatability.Here,we explored a highly reproducible free-standing liquid-state platf...Surface-enhanced Raman scattering(SERS)has been widely used in various fields due to high sensitivity,but it is hindered by its low repeatability.Here,we explored a highly reproducible free-standing liquid-state platform(FSM)for monitoring norfloxacin(NOR)in the environmental field.After optimizing the types of nanoparticles(NPs)and pH value in NOR solution,the relative standard deviation(RSD)of FSM SERS analysis can be stabilized below 10%(n≥8),and the R^(2)of the calibration curve in the range of 20μg/L-100μg/L was 0.995.In addition,the results showed that the limit of detection(LOD)(3σ/k)of NOR was 1.3μg/L.Moreover,the NOR in the spiked samples was successfully quantified by FSM,and the recovery rate exceeded 95%.The proposed method has the potential for rapid analysis of drug residues in environmental samples.展开更多
基金financially supported of the National Natural Science Foundation of China(22006121,22076153)Sichuan Science and Technology Program(2020YFH0048)
文摘Surface-enhanced Raman scattering(SERS)has been widely used in various fields due to high sensitivity,but it is hindered by its low repeatability.Here,we explored a highly reproducible free-standing liquid-state platform(FSM)for monitoring norfloxacin(NOR)in the environmental field.After optimizing the types of nanoparticles(NPs)and pH value in NOR solution,the relative standard deviation(RSD)of FSM SERS analysis can be stabilized below 10%(n≥8),and the R^(2)of the calibration curve in the range of 20μg/L-100μg/L was 0.995.In addition,the results showed that the limit of detection(LOD)(3σ/k)of NOR was 1.3μg/L.Moreover,the NOR in the spiked samples was successfully quantified by FSM,and the recovery rate exceeded 95%.The proposed method has the potential for rapid analysis of drug residues in environmental samples.
