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Inverting the rock mass P-wave velocity field ahead of deep buried tunnel face while borehole drilling
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作者 liu liu shaojun li +5 位作者 Minzong Zheng Dong Wang Minghao Chen Junbo Zhou Tingzhou Yan Zhenming Shi 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第5期681-697,共17页
Imaging the wave velocity field surrounding a borehole while drilling is a promising and urgently needed approach for extending the exploration range of the borehole point.This paper develops a drilling process detect... Imaging the wave velocity field surrounding a borehole while drilling is a promising and urgently needed approach for extending the exploration range of the borehole point.This paper develops a drilling process detection(DPD)system consisting of a multifunctional sensor and a pilot geophone installed at the top of the drilling rod,geophones at the tunnel face,a laser rangefinder,and an onsite computer.A weighted adjoint-state first arrival travel time tomography method is used to invert the P-wave velocity field of rock mass while borehole drilling.A field experiment in the ongoing construction of a deep buried tunnel in southwestern China demonstrated the DPD system and the tomography method.Time-frequency analysis of typical borehole drilling detection data shows that the impact drilling source is a pulse-like seismic exploration wavelet.A velocity field of the rock mass in a triangular area defined by the borehole trajectory and geophone receiving line can be obtained.Both the borehole core and optical image validate the inverted P-wave velocity field.A numerical simulation of a checkerboard benchmark model is used to test the tomography method.The rapid convergence of the misfits and consistent agreement between the inverted and observed travel times validate the P-wave velocity imaging. 展开更多
关键词 Deep buried tunnel Wave velocity field Borehole drilling Tomography Rock mass
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Uncertainty quantification of inverse analysis for geomaterials using probabilistic programming
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作者 Hongbo Zhao shaojun li +3 位作者 Xiaoyu Zang Xinyi liu lin Zhang Jiaolong Ren 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第3期895-908,共14页
Uncertainty is an essentially challenging for safe construction and long-term stability of geotechnical engineering.The inverse analysis is commonly utilized to determine the physico-mechanical parameters.However,conv... Uncertainty is an essentially challenging for safe construction and long-term stability of geotechnical engineering.The inverse analysis is commonly utilized to determine the physico-mechanical parameters.However,conventional inverse analysis cannot deal with uncertainty in geotechnical and geological systems.In this study,a framework was developed to evaluate and quantify uncertainty in inverse analysis based on the reduced-order model(ROM)and probabilistic programming.The ROM was utilized to capture the mechanical and deformation properties of surrounding rock mass in geomechanical problems.Probabilistic programming was employed to evaluate uncertainty during construction in geotechnical engineering.A circular tunnel was then used to illustrate the proposed framework using analytical and numerical solution.The results show that the geomechanical parameters and associated uncertainty can be properly obtained and the proposed framework can capture the mechanical behaviors under uncertainty.Then,a slope case was employed to demonstrate the performance of the developed framework.The results prove that the proposed framework provides a scientific,feasible,and effective tool to characterize the properties and physical mechanism of geomaterials under uncertainty in geotechnical engineering problems. 展开更多
关键词 Geological engineering Geotechnical engineering Inverse analysis Uncertainty quantification Probabilistic programming
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Three-dimensional stress variation characteristics in deep hard rock of CJPL-Ⅱ project based on in-situ monitoring
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作者 Minzong Zheng shaojun li +2 位作者 Zejie Feng Huaisheng Xu Yaxun Xiao 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第2期179-195,共17页
In deep hard rock excavation, stress plays a pivotal role in inducing stress-controlled failure. While the impact of excavation-induced stress disturbance on rock failure and tunnel stability has undergone comprehensi... In deep hard rock excavation, stress plays a pivotal role in inducing stress-controlled failure. While the impact of excavation-induced stress disturbance on rock failure and tunnel stability has undergone comprehensive examination through laboratory tests and numerical simulations, its validation through insitu stress tests remains unexplored. This study analyzes the three-dimensional stress changes in the surrounding rock at various depths, monitored during the excavation of B2 Lab in China Jinping Underground Laboratory Phase Ⅱ(CJPL-Ⅱ). The investigation delves into the three-dimensional stress variation characteristics in deep hard rock, encompassing stress components and principal stress. The results indicate changes in both the magnitude and direction of the principal stress during tunnel excavation. To quantitatively describe the degree of stress disturbance, a series of stress evaluation indexes are established based on the distances between stress tensors, including the stress disturbance index(SDI), the principal stress magnitude disturbance index(SDIm), and the principal stress direction disturbance index(SDId). The SDI indicates the greatest stress disturbance in the surrounding rock is 4.5 m from the tunnel wall in B2 Lab. SDIm shows that the principal stress magnitude disturbance peaks at2.5 m from the tunnel wall. SDId reveals that the largest change in principal stress direction does not necessarily occur near the tunnel wall but at a specific depth from it. The established relationship between SDI and the depth of the excavation damaged zone(EDZ) can serve as a criterion for determining the depth of the EDZ in deep hard rock engineering. Additionally, it provides a reference for future construction and support considerations. 展开更多
关键词 Disturbance stress Tensor distance Stress disturbance index Principal stress direction Underground research laboratory
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Microdynamic mechanical properties and fracture evolution mechanism of monzogabbro with a true triaxial multilevel disturbance method
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作者 Zhi Zheng Bin Deng +3 位作者 Hong liu Wei Wang Shuling Huang shaojun li 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第3期385-411,共27页
The far-field microdynamic disturbance caused by the excavation of deep mineral resources and underground engineering can induce surrounding rock damage in high-stress conditions and even lead to disasters.However,the... The far-field microdynamic disturbance caused by the excavation of deep mineral resources and underground engineering can induce surrounding rock damage in high-stress conditions and even lead to disasters.However,the mechanical properties and damage/fracture evolution mechanisms of deep rock induced by microdynamic disturbance under three-dimensional stress states are unclear.Therefore,a true triaxial multilevel disturbance test method is proposed,which can completely simulate natural geostress,excavation stress redistribution(such as stress unloading,concentration and rotation),and subsequently the microdynamic disturbance triggering damaged rock failure.Based on a dynamic true triaxial test platform,true triaxial microdynamic disturbance tests under different frequency and amplitudes were carried out on monzogabbro.The results show that increasing amplitude or decreasing frequency diminishes the failure strength of monzogabbro.Deformation modulus gradually decreases during disturbance failure.As frequency and amplitude increase,the degradation rate of deformation modulus decreases slightly,disturbance dissipated energy increases significantly,and disturbance deformation anisotropy strengthens obviously.A damage model has been proposed to quantitatively characterize the disturbance-induced damage evolution at different frequency and amplitude under true triaxial stress.Before disturbance failure,the micro-tensile crack mechanism is dominant,and the micro-shear crack mechanism increases significantly at failure.With the increase of amplitude and frequency,the micro-shear crack mechanism increases.When approaching disturbance failure,the acoustic emission fractal dimension changes from a stable value to local large oscillation,and finally increases sharply to a high value at failure.Finally,the disturbance-induced failure mechanism of surrounding rock in deep engineering is clearly elucidated. 展开更多
关键词 True triaxial disturbance test Mechanical properties Fracture evolution mechanism Disturbance-induced damage evolution Failure mechanism and precursor
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Investigation of stress-induced progressive failure of mine pillars using a Voronoi grain-based breakable block model
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作者 Shili Qiu Shirui Zhang +3 位作者 Quan Jiang shaojun li Hao Zhang Qiankuan Wang 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第5期713-729,共17页
The Voronoi grain-based breakable block model(VGBBM)based on the combined finite-discrete element method(FDEM)was proposed to explicitly characterize the failure mechanism and predict the deformation behavior of hard-... The Voronoi grain-based breakable block model(VGBBM)based on the combined finite-discrete element method(FDEM)was proposed to explicitly characterize the failure mechanism and predict the deformation behavior of hard-rock mine pillars.The influence of the microscopic parameters on the macroscopic mechanical behavior was investigated using laboratory-scale models.The field-scale pillar models(width-to-height,W/H=1,2 and 3)were calibrated based on the empirically predicted stress-strain curves of Creighton mine pillars.The results indicated that as the W/H ratios increased,the VGBBM effectively predicted the transition from strain-softening to pseudo-ductile behavior in pillars,and explicitly captured the separated rock slabs and the V-shaped damage zones on both sides of pillars and conjugate shear bands in core zones of pillars.The volumetric strain field revealed significant compressional deformation in core zones of pillars.While the peak strains of W/H=1 and 2 pillars were relatively consistent,there were significant differences in the strain energy storage and release mechanism.W/H was the primary factor influencing the deformation and strain energy in the pillar core.The friction coefficient of the structural plane was also an important factor affecting the pillar strength and the weakest discontinuity angle.The fracture surface was controlled by the discontinuity angle and the friction coefficient.This study demonstrated the capability of the VGBBM in predicting the strengths and deformation behavior of hard-rock pillars in deep mine design. 展开更多
关键词 Pillar strength FDEM Voronoi tessellation SPALLING BULKING
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Probabilistic analysis of tunnel displacements based on correlative recognition of rock mass parameters 被引量:10
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作者 Minzong Zheng shaojun li +2 位作者 Hongbo Zhao Xiang Huang Shili Qiu 《Geoscience Frontiers》 SCIE CAS CSCD 2021年第4期46-60,共15页
Displacement is vital in the evaluations of tunnel excavation processes,as well as in determining the postexcavation stability of surrounding rock masses.The prediction of tunnel displacement is a complex problem beca... Displacement is vital in the evaluations of tunnel excavation processes,as well as in determining the postexcavation stability of surrounding rock masses.The prediction of tunnel displacement is a complex problem because of the uncertainties of rock mass properties.Meanwhile,the variation and the correlation relationship of geotechnical material properties have been gradually recognized by researchers in recent years.In this paper,a novel probabilistic method is proposed to estimate the uncertainties of rock mass properties and tunnel displacement,which integrated multivariate distribution function and a relevance vector machine(RVM).The multivariate distribution function is used to establish the probability model of related random variables.RVM is coupled with the numerical simulation methods to construct the nonlinear relationship between tunnel displacements and rock mass parameters,which avoided a large number of numerical simulations.Also,the residual rock mass parameters are taken into account to reflect the brittleness of deeply buried rock mass.Then,based on the proposed method,the uncertainty of displacement in a deep tunnel of CJPL-II laboratory are analyzed and compared with the in-situ measurements.It is found that the predicted tunnel displacements by the RVM model closely match with the measured ones.The correlations of parameters have significant impacts on the uncertainty results.The uncertainty of tunnel displacement decreases while the reliability of the tunnel increases with the increases of the negative correlations among rock mass parameters.When compared to the deterministic method,the proposed approach is more rational and scientific,and also conformed to rock engineering practices. 展开更多
关键词 UNCERTAINTIES CORRELATION DISPLACEMENT Multivariate distributions Relevance vector machine
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A subspace ensemble regression model based slow feature for soft sensing application 被引量:1
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作者 Qiong Jia Jun Cai +1 位作者 Xinyi Jiang shaojun li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2020年第12期3061-3069,共9页
A novel adaptive subspace ensemble slow feature regression model was developed for soft sensing application.Compared to traditional single models and random subspace models,the proposed method is improved in three asp... A novel adaptive subspace ensemble slow feature regression model was developed for soft sensing application.Compared to traditional single models and random subspace models,the proposed method is improved in three aspects.Firstly,sub-datasets are constructed through slow feature directions and variables in each subdatasets are selected according to the output related importance index.Then,an adaptive slow feature regression is presented for sub-models.Finally,a Bayesian inference strategy based on a slow feature analysis process that monitors statistics is developed for probabilistic combination.Two industrial examples were used to evaluate the proposed method. 展开更多
关键词 Soft sensing Slow feature regression Subspace modeling Ensemble learning
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Amplification effect of near-field ground motion around deep tunnels based on finite fracturing seismic source model
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作者 Qiankuan Wang Shili Qiu +4 位作者 Yao Cheng shaojun li Ping li Yong Huang Shirui Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2022年第6期1761-1781,共21页
Dynamic failure of rock masses around deep tunnels,such as fault-slip rockburst and seismic-induced collapse,can pose a significant threat to tunnel construction safety.One of the most significant factors that control... Dynamic failure of rock masses around deep tunnels,such as fault-slip rockburst and seismic-induced collapse,can pose a significant threat to tunnel construction safety.One of the most significant factors that control the accuracy of its risk assessment is the estimation of the ground motion around a tunnel caused by seismicity events.In general,the characteristic parameters of ground motion are estimated in terms of empirical scaling laws.However,these scaling laws make it difficult to accurately estimate the near-field ground motion parameters because the roles of control factors,such as tunnel geometry,damage zone distribution,and seismic source parameters,are not considered.For this,the finite fracturing seismic source model(FFSSM)proposed in this study is used to simulate the near-field ground motion characteristics around deep tunnels.Then,the amplification effects of ground motion caused by the interaction between seismic waves and deep tunnels and corresponding control factors are studied.The control effects of four factors on the near-field ground motion amplification effect are analyzed,including the main seismic source wavelength,tunnel span,tunnel shape,and range of damage zones.An empirical formula for the maximum amplification factor(a_(m))of the near-field ground motion around deep tunnels is proposed,which consists of four control factors,i.e.the wavelength control factor(F_(λ)),tunnel span factor(F_(D)),tunnel shape factor(F_(s))and excavation damage factor(F_(d)).This empirical formula provides an easy approach for accurately estimating the ground motion parameters in seismicityprone regimes and the rock support design of deep tunnels under dynamic loads. 展开更多
关键词 Near-field ground motion Amplification effect Seismic waves Deep tunnel ROCKBURST
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In-situ observations of damage-fracture evolution in surrounding rock upon unloading in 2400-m-deep tunnels 被引量:11
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作者 Haosen Guo Qiancheng Sun +2 位作者 Guangliang Feng shaojun li Yaxun Xiao 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2023年第4期437-446,共10页
The damage-fracture evolution of deep rock mass has obvious particularity,which is revealed in 2400-mdeep tunnels by field tests.The evolution of the excavation damaged zone depth is consistent with that of the fractu... The damage-fracture evolution of deep rock mass has obvious particularity,which is revealed in 2400-mdeep tunnels by field tests.The evolution of the excavation damaged zone depth is consistent with that of the fractured zone depth.The ratio of the excavation damaged zone depth to the excavation fractured zone depth is greater than 2.0 in a rock mass with both high strength and good integrity,but less than1.5 in a rock mass with lower strength or poor integrity.Zonal disintegration in a rock mass with high strength and fair integrity is more likely to occur when it contains more than two groups of primary fractures in damaged zones.Fractures develop outward in zonal disintegration but are totally different from the single-zone fracture,in which the fractures develop inward,and it is the starting position of the fractured zone when the excavation surface of the middle pilot is 7–9 m close to the pre-set borehole and it stops after the excavation surface of the baseplate is 11–14 m away.The most intense evolution occurs around 2–4 m from the pre-set borehole in the sidewall expansion stage.The research results provide a reference for the monitoring scheme and support design of CJPL-Ⅲin its future construction. 展开更多
关键词 Deep tunnel Fractured zone Damaged zone In-situ observation Unloading of rock mass
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肺腺癌长链非编码RNA启动子DNA甲基化的生物信息学分析
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作者 张文 李少军 +1 位作者 郭楠楠 赵英男 《中国肺癌杂志》 CAS CSCD 北大核心 2018年第6期470-475,共6页
背景与目的肿瘤相关长链非编码RNA(linc RNA)的异常表达影响癌症的进程,是肿瘤进展机制研究的热点,然而其调控机制目前并不清楚。本研究通过生物信息学方法研究肺腺癌linc RNA启动子DNA甲基化水平与基因表达和预后的关系。方法从TCGA网... 背景与目的肿瘤相关长链非编码RNA(linc RNA)的异常表达影响癌症的进程,是肿瘤进展机制研究的热点,然而其调控机制目前并不清楚。本研究通过生物信息学方法研究肺腺癌linc RNA启动子DNA甲基化水平与基因表达和预后的关系。方法从TCGA网站下载肺腺癌Illumina Methylation 450K芯片的全基因组DNA甲基化数据及转录组数据,分析DNA甲基化在linc RNA基因附近的分布情况及与基因表达的关系;比较肿瘤组织和癌旁组织DNA甲基化和表达变化。结果 linc RNA启动子附近DNA甲基化水平较低,且与基因的表达水平呈负相关。在肿瘤组织和癌旁组织间,15个linc RNA的DNA甲基化水平存在显著差异,与其表达呈反向变化,包括与癌症发生发展相关的FINDER基因,该基因启动子高甲基化的肺腺癌病人预后较差,与基因表达作用刚好相反。结论肺腺癌中一些linc RNA启动子的DNA甲基化水平能调控linc RNA的表达,进而与肺腺癌的预后有关。 展开更多
关键词 肺腺癌 LincRNA DNA甲基化 预后
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Studies on the evolution process of rockbursts in deep tunnels 被引量:16
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作者 Xiating Feng Bingrui Chen +9 位作者 shaojun li Chuanqing Zhang Yaxun Xiao Guangliang Feng Hui Zhou Shili Qiu Zhouneng Zhao Yang Yu Dongfang Chen Huajun Ming 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE 2012年第4期289-295,共7页
This paper focuses on the evolution processes of different types of rockbursts occurring in deep tunnels. A series of laboratory tests and in-situ monitoring in deep tunnels excavated by tunnel boring machine (TBM) ... This paper focuses on the evolution processes of different types of rockbursts occurring in deep tunnels. A series of laboratory tests and in-situ monitoring in deep tunnels excavated by tunnel boring machine (TBM) and drill-and-blast (D&B) method have been conducted to understand the mechanisms and processes of the evolution of different types of rockbursts, including strain rockburst, strain-structure slip rockburst, immediate rockburst and time-delayed rockburst. Three different risk assessment methods are proposed to evaluate the intensity and potential failure depth of rockbursts. These methods can be applied before excavation and the results can be updated according to the real-time information during excavation. Two micro-seismicity based real-time warning systems have been established for predicting various intensities ofrockbursts, such as slight, moderate, intensive and extremely intensive rockbursts. Meanwhile, the probability and intensity of the rockburst are also given. The strategy for excavation and support design has been suggested for various intensities of rockbursts before excavation. The strategy for dynamic control of the rockburst evolution process is also proposed according to the monitoring results. The methodology has been successfully applied to rockburst risk reduction for deep tunnels at Jinping II hydropower project. The results have illustrated the applicability of the proposed methodology and techniques concerning rockbursts. 展开更多
关键词 ROCKBURST risk assessment tunnel boring machine (TBM) drill-and-blast (D&B) method
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Estimation of the three-dimensional in situ stress field around a large deep underground cavern group near a valley 被引量:10
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作者 Dingping Xu Xiang Huang +7 位作者 Quan Jiang shaojun li Hong Zheng Shili Qiu Huaisheng Xu Yonghong li Zhiguo li Xingdong Ma 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2021年第3期529-544,共16页
Understanding three-dimensional(3D)in situ stress field is of key importance for estimating the stability of large deep underground cavern groups near valleys.However,the complete 3D in situ stress fields around large... Understanding three-dimensional(3D)in situ stress field is of key importance for estimating the stability of large deep underground cavern groups near valleys.However,the complete 3D in situ stress fields around large deep underground cavern groups are difficult to determine based on in situ stress data from a limited number of measuring points due to the insufficient representativeness and unreliability of such measurements.In this study,an integrated approach for estimating the 3D in situ stress field around a large deep underground cavern group near a valley is developed based on incomplete in situ stress measurements and the stress-induced failures of tunnels excavated prior to the step excavation of the cavern group.This integrated approach is implemented via four interrelated and progressive basic steps,i.e.inference of the regional tectonic stress field direction,analyses of in situ stress characteristics and measurement reliability,regression-based in situ stress field analysis and reliability assessment,and modified in situ stress field analysis and reliability verification.The orientations and magnitudes of the 3D in situ stress field can be analyzed and obtained at a strategic level following these four basic steps.First,the tectonic stress field direction around the cavern group is deduced in accordance with the regional tectonic framework and verified using a regional crustal deformation velocity map.Second,the reliability of the in situ stress measurements is verified based on the locations and depths of stressinduced brittle failures in small tunnels(such as exploratory tunnels and pilot tunnels)within the excavation range of the cavern group.Third,considering the influences of the valley topography and major geological structures,the 3D in situ stress field is regressed using numerical simulation and multiple linear regression techniques based on the in situ stress measurements.Finally,the regressed in situ stress field is further modified and reverified based on the stress-induced brittle failures of small tunnels and the initial excavation of the cavern group.A case study of the Shuangjiangkou underground cavern group demonstrates that the proposed approach is reliable for estimating the 3D in situ stress fields of large deep underground cavern groups near valleys,thus contributing to the optimization of practical excavation and design of mitigating the instability of the surrounding rock masses during step excavations. 展开更多
关键词 Underground cavern group In situ stress Stress-induced brittle failure Spalling depth Numerical simulation
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A local homogenization approach for simulating the reinforcement effect of the fully grouted bolt in deep underground openings 被引量:6
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作者 Dingping Xu Xiuyang liu +6 位作者 Quan Jiang shaojun li Yangyi Zhou Shili Qiu Fei Yan Hong Zheng Xiang Huang 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2022年第2期247-259,共13页
Fully grouted bolts are a key component of the support system for underground openings.Although considerable effort has been made in the simulation of the reinforcement effect of the fully grouted bolts on the rock ma... Fully grouted bolts are a key component of the support system for underground openings.Although considerable effort has been made in the simulation of the reinforcement effect of the fully grouted bolts on the rock masses surrounding underground openings,most of the work has limited significance since the structural element approach is used.This study proposes a local homogenization approach(L-H approach)that integrates elastoplastic mechanics,composite mechanics,and analytical approaches with numerical simulation to effectively simulate the reinforcement effect of the fully grouted bolt on deep surrounding rock masses.In the L-H approach,the representative volume of bolted rock mass(RVBRM)with a fully grouted bolt is established based on the original mesh model utilized in the rockbolt element approach.The RVBRM is a regular quadrangular prism with a cross-sectional size equal to the bolt spacing and a length equal to the bolt length.The RVBRM is homogenized by the L-H approach from a unidirectional bolt-reinforced composite into a homogeneous transversely isotropic medium whose mechanical properties are described by a new transversely isotropic elastoplastic model.The L-H parameters for the RVBRM are obtained using analytical approaches,composite mechanics,and known parameters of the rock mass and bolt.Using the L-H approach,the reinforcement effect of the fully grouted bolt on the bolted rock specimen and the surrounding rock mass in Jinping II Diversion Tunnel#2 with a depth greater than 2000 m is simulated.The results show that the predictions of the L-H approach are more in agreement with the physical model results of bolted rock specimen and provide a more realistic response of the bolted surrounding rock mass.The L-H approach demonstrates that fully grouted bolts with common bolt spacings and diameters substantially enhance the elastic modulus,shear strength,and tensile strength of the rock mass in the direction of the bolt axis. 展开更多
关键词 Fully grouted bolt Reinforcement effect Representative volume Transverse isotropy HOMOGENIZATION
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Updating the models and uncertainty of mechanical parameters for rock tunnels using Bayesian inference 被引量:2
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作者 Hongbo Zhao Bingrui Chen +2 位作者 shaojun li Zhen li Changxing Zhu 《Geoscience Frontiers》 SCIE CAS CSCD 2021年第5期224-236,共13页
Rock mechanical parameters and their uncertainties are critical to rock stability analysis,engineering design,and safe construction in rock mechanics and engineering.The back analysis is widely adopted in rock enginee... Rock mechanical parameters and their uncertainties are critical to rock stability analysis,engineering design,and safe construction in rock mechanics and engineering.The back analysis is widely adopted in rock engineering to determine the mechanical parameters of the surrounding rock mass,but this does not consider the uncertainty.This problem is addressed here by the proposed approach by developing a system of Bayesian inferences for updating mechanical parameters and their statistical properties using monitored field data,then integrating the monitored data,prior knowledge of geotechnical parameters,and a mechanical model of a rock tunnel using Markov chain Monte Carlo(MCMC)simulation.The proposed approach is illustrated by a circular tunnel with an analytical solution,which was then applied to an experimental tunnel in Goupitan Hydropower Station,China.The mechanical properties and strength parameters of the surrounding rock mass were modeled as random variables.The displacement was predicted with the aid of the parameters updated by Bayesian inferences and agreed closely with monitored displacements.It indicates that Bayesian inferences combined the monitored data into the tunnel model to update its parameters dynamically.Further study indicated that the performance of Bayesian inferences is improved greatly by regularly supplementing field monitoring data.Bayesian inference is a significant and new approach for determining the mechanical parameters of the surrounding rock mass in a tunnel model and contributes to safe construction in rock engineering. 展开更多
关键词 Rock tunnel engineering Back analysis Bayesian inference Uncertainty analysis Markov chain Monte Carlo simulation
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State-of-the-art progress in the selective photo-oxidation of alcohols 被引量:1
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作者 Zewen Shen Yezi Hu +6 位作者 Bingfeng li Yingtong Zou shaojun li GWilma Busser Xiangke Wang Guixia Zhao Martin Muhler 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2021年第11期338-350,I0007,共14页
Photocatalytic oxidation of alcohols has received more and more attention in recent years following the numerous studies on the degradation of pollutants, hydrogen evolution, and CO_(2) reduction by photocatalysis. In... Photocatalytic oxidation of alcohols has received more and more attention in recent years following the numerous studies on the degradation of pollutants, hydrogen evolution, and CO_(2) reduction by photocatalysis. Instead of the total oxidation of organics in the degradation process, the photo-oxidation of alcohols aims at the selective conversion of alcohols to produce carbonyl/acid compounds. Promising results have been achieved in designing the catalysts and reaction system, as well as in the mechanistic investigations in the past few years. This review summarizes the state-of-the-art progress in the photo-oxidation of alcohols, including the development of photocatalysts and cocatalysts, reaction conditions including the solvent and the atmosphere, and the exploration of mechanisms with scavengers experiment, electron paramagnetic resonance (EPR) and diffuse reflectance infrared Fourier transform (DRIFT) spectroscopy. The challenges and outlook for the further research in this field are also discussed. 展开更多
关键词 Alcohol oxidation PHOTOCATALYSIS Carbonyl compounds SELECTIVITY
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The study on DNA methylation of p53-Bax mitochondrial apoptosis pathway in cholangiocarcinoma
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作者 Xiaofang liu Yongliang Duan +4 位作者 Fanmin Kong Zheng Xu Xianting Zhou Cuisheng Zhang shaojun li 《The Chinese-German Journal of Clinical Oncology》 CAS 2009年第4期214-218,共5页
Objective: To study the methylation status of several genes on p53-Bax mitochondrial apoptosis pathway and clinical significance in cholangiocarcinoma. Methods: Promoter hypermethylation of DAPK, p14 and ASC genes w... Objective: To study the methylation status of several genes on p53-Bax mitochondrial apoptosis pathway and clinical significance in cholangiocarcinoma. Methods: Promoter hypermethylation of DAPK, p14 and ASC genes were detected by methylation-specific PCR. p53 gene status (exon 5-8) were examined by automated sequencing, combined with the clinical documents of patients by statistics analysis. Results: (1) We found 66.7% of 36 cases cholangiocarcinoma had methylation of at least one tumor suppressor gene. The frequency of tumor suppressor gene methylation in cholangiocarcinoma was: p14 (24%), DAPK (30.6%), TMSI/ASC (36.1%). The frequency of tumor suppressor gene methylation in tissues near cancer was: DAPK (5.6%), TMS1/ASC (8.3%). (2) p53 gene mutations were found in 22 of 36 patients (61.1%). (3) There were no statistically relationship among the methylation of DAPK, p14 and ASC genes. There were negative relationship differences between the methylation of p14 and p53 gene mutation (P 〈 0.05). (4) p53 gene mutation combined with the methylation of tumor suppressor were 14 cases (38.9%). There were statistically differences on extent of pathologic biology, differentiation and invasion (P 〈 0.05). Conclusion: Our study indicated that methylation of p53-Bax mitochondrial apoptosis pathway in cholangiocarcinoma was a common epigenetic event. Although the methylation of ASC, DAPK genes was low, it might be significance for early diagnosis, p53 gene mutation combined with the methylation of tumor suppressor might be relationship with pathologic biology, it trended to more malignancy. 展开更多
关键词 CHOLANGIOCARCINOMA methylation specific PCR p53-Bax mitochondrial apoptosis pathway
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Rapid and selective uranium extraction from aqueous solution under visible light in the absence of solid photocatalyst 被引量:6
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作者 shaojun li Yezi Hu +7 位作者 Zewen Shen Yawen Cai Zhuoyu Ji Xiaoli Tan Zhixin liu Guixia Zhao Shuxian Hu Xiangke Wang 《Science China Chemistry》 SCIE EI CSCD 2021年第8期1323-1331,共9页
Extraction of uranium from radioactive waste-water is of significant importance for environmental protection and the recovery of uranium resource.Different from the previous reports to use the solid absorbent/photocat... Extraction of uranium from radioactive waste-water is of significant importance for environmental protection and the recovery of uranium resource.Different from the previous reports to use the solid absorbent/photocatalyst for U(VI)removal,herein,we proposed a new eco-friendly method for the rapid and selective extraction of uranium from aqueous solutions under visible light without solid materials.At optimal pH value and in the presence of organics like alcohols,the U(VI)could be extracted efficiently to form brown uranium solid over wide uranium concentrations under anaerobic condition and visible light,by utilizing the excitation of the given U(VI)species.With comprehensive modelling of the electronic ultraviolet-visible(UV-Vis)properties,it is proved that pH adjusting towards U(VI)could induce efficient ligand-to-metal-charge-transfer(LMCT)within the uranyl complex under visible light and the reduction of U(VI)to form U(V),which can be transformed into U(IV)via disproportionation reaction.The resulting U(IV)in solid phase makes the extraction much more convenient in operation.More importantly,the excellent selectivity for uranium extraction over interfering alkali metal ions,transition metal ions and the lanthanide metal ions shows a powerful application potential. 展开更多
关键词 uranyl removal solidification PHOTOREDUCTION visible light selective extraction
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西太平洋中生代板块俯冲过程与东亚洋陆过渡带构造-岩浆响应 被引量:74
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作者 李三忠 索艳慧 +11 位作者 李玺瑶 王永明 曹现志 王鹏程 郭玲莉 于胜尧 兰浩圆 李少俊 赵淑娟 周在征 张臻 张国伟 《科学通报》 EI CAS CSCD 北大核心 2018年第16期1550-1593,共44页
中生代期间,华北与华南地块受西太平洋的板块俯冲过程、东亚大陆边缘深浅部过程的影响,其构造、岩浆、成矿、地貌演化趋势表现出一些共性,但也存在显著差异,其动力机制一般认为由古太平洋板块俯冲所致,但是它们是如何关联的,长期未得到... 中生代期间,华北与华南地块受西太平洋的板块俯冲过程、东亚大陆边缘深浅部过程的影响,其构造、岩浆、成矿、地貌演化趋势表现出一些共性,但也存在显著差异,其动力机制一般认为由古太平洋板块俯冲所致,但是它们是如何关联的,长期未得到解决,是地质研究的难点和热点,存在巨大争论.本文系统评述了近十年来已有东亚大陆边缘的构造变形分析、岩浆岩年代学、层析成像等多学科成就,简要探讨了前燕山期的中国陆块的最终聚合、统一陆缘的形成,随后主要侧重综述侏罗纪、白垩纪东亚洋陆过渡带燕山期地质过程的新认识.本文将浅部构造变形规律、岩浆岩年龄分带和迁移、地形巨大反转,与深部过程紧密结合,提出:华北克拉通破坏过程总体受深部岩石圈早幕向西的分层回卷拆沉、减薄制约,导致早期构造、岩浆作用伴随西迁,中幕多向拆沉,晚幕拆沉向东回撤;同时,北部鄂霍茨克洋闭合与南部班公湖-怒江俯冲系统的同期联合作用使得东亚洋陆过渡带总体处于挤压背景下,且深部上涌的软流圈不断向东跃迁,带动岩石圈不断向东、幕式、交替性伸展和挤压.华南深部早期则经历了向西平板俯冲,导致变形和岩浆作用西迁;后期发生两幕拆沉,导致构造-岩浆作用向东跃迁.总之,华北与华南构造-岩浆差异的内因是深部过程,外因是东亚大汇聚的差异所致. 展开更多
关键词 洋陆过渡带 古太平洋板块 东亚 燕山期 大陆边缘 俯冲后撤
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