To the Editor:Recurrent pregnancy loss(RPL)is defined as two or more consecutive spontaneous pregnancy losses before 24 weeks of gestation;it affects 1-2%of couples.[1]Some causes of RPL are uterine anatomical abnorma...To the Editor:Recurrent pregnancy loss(RPL)is defined as two or more consecutive spontaneous pregnancy losses before 24 weeks of gestation;it affects 1-2%of couples.[1]Some causes of RPL are uterine anatomical abnormalities,abnormal chromosomes in parents or embryos,antiphospholipid syndrome,and certain autoimmune disorders.[2]However,the etiology of 40-50%of RPL couples remains unclear and is defined as unexplained RPL(uRPL).展开更多
基金supported by grants from the National Key Research and Development Program(No.2021YFC2700604)General Program of National Natural Science Foundation of China(No.82171648)+5 种基金Shandong Provincial Key Research and Development Program(No.2021LCZX02)Youth Program of National Natural Science Foundation of China(No.82101752)Youth Program of Shandong Provincial Natural Science Foundation of China(No.ZR2021QH075)Taishan Scholars Program for Young Experts of Shandong Province(No.tsqn202312388)the Shandong Provincial Medical and Health Science and Technology Development Program(No.2019WS171)the Shandong Provincial Natural Science Foundation(No.ZR2020MH072).
文摘To the Editor:Recurrent pregnancy loss(RPL)is defined as two or more consecutive spontaneous pregnancy losses before 24 weeks of gestation;it affects 1-2%of couples.[1]Some causes of RPL are uterine anatomical abnormalities,abnormal chromosomes in parents or embryos,antiphospholipid syndrome,and certain autoimmune disorders.[2]However,the etiology of 40-50%of RPL couples remains unclear and is defined as unexplained RPL(uRPL).