Objective:To investigate the effect of TSH inhibition therapy in the postoperative management of patients with differentiated thyroid cancer.Methods:Seventy patients diagnosed with differentiated thyroid cancer were s...Objective:To investigate the effect of TSH inhibition therapy in the postoperative management of patients with differentiated thyroid cancer.Methods:Seventy patients diagnosed with differentiated thyroid cancer were selected for the study.TSH inhibition therapy was administered to the research group,while thyroxine replacement therapy was provided to the control group during the postoperative management phase.This allowed for a comparative analysis between the two groups.Results:In comparison with the control group,the research group exhibited significant decreases in serum TSH,T3,and T4 levels after treatment,while FT4 and FT3 levels significantly increased(P<0.05).Additionally,significant decreases in Tg,VEGF,TSGF,CD44V6,and sIL-2R levels were observed in the research group after treatment(P<0.05).No significant differences were found in pre-treatment thyroid function between the two groups(P>0.05).Conclusion:The application of TSH inhibition therapy in the postoperative management of patients with differentiated thyroid cancer demonstrates promising outcomes.展开更多
Objective:To analyze the effect of thyroid-stimulating hormone(TSH)suppression therapy on sex hormone levels in patients undergoing postoperative treatment for thyroid cancer.Methods:A total of 40 patients undergoing ...Objective:To analyze the effect of thyroid-stimulating hormone(TSH)suppression therapy on sex hormone levels in patients undergoing postoperative treatment for thyroid cancer.Methods:A total of 40 patients undergoing postoperative thyroid cancer treatment were selected for data analysis.TSH suppression therapy was implemented during the postoperative period.Patients were grouped according to the TSH level:TSH<0.1,0.1≤TSH<0.5,and TSH≥0.5.Results:Among male patients,there were no significant differences in sex hormone levels at different dosing times and TSH levels(P>0.05).For female patients,testosterone levels at different dosing times showed no significant differences under the same circumstances(P>0.05).The comparison of testosterone levels at different TSH levels over 5 years of TSH suppression therapy did not yield significant differences(P>0.05).However,the comparison of testosterone levels within 5 years of TSH suppression therapy yielded significant differences(P<0.05),with the lowest levels observed at 0.1≤TSH<0.5.Conclusion:The use of TSH suppression therapy in postoperative thyroid cancer treatment minimally affects sex hormone levels in male patients.However,it has a significant impact on female patients.Therefore,preoperative sex hormone testing is recommended,and postoperative monitoring should include regular sex hormone testing.展开更多
The Yinggehai Basin is a unique NNW-trending petroliferous basin in the northwestern South China Sea.This paper mainly utilized stratigraphic,tectonic and seismic data by characterizing the geological structures and c...The Yinggehai Basin is a unique NNW-trending petroliferous basin in the northwestern South China Sea.This paper mainly utilized stratigraphic,tectonic and seismic data by characterizing the geological structures and conducting the geo-mechanical analysis to study the formation,evolution and dynamics of the Yinggehai Basin.The study indicates that the Ailaoshan-Truong Son extruded terrane is composed of multiple secondary extruded bodies.The Red River fault zone,located within the Qiangtang-Simao-Yinggehai mantle flow channel and basin zone,experienced transform-type sinistral strike-slip motion before the basin forming stage and formed a NW-trending extruded mantle uplift,which activated the Yinggehai basin.After experiencing the rift depression,fault depression,and fault subsidence,the basin eventually formed large-scale,thick sedimentation features with ideal hydrocarbon-forming conditions at the end of the Miocene.Later,the basin dynamically transformed and entered a period of tectonic superposition,reworking,and thermal subsidence.Superposition of the NNW thrust sinistral strike-slip fault zone on the northern Hanoi sub-basin complicated the basin structure.Since the Pliocene,the southern Yinggehai main basin has been transformed into an extensional dextral strike-slip environment that hosted numerous mud diapirs.The thin crust and high geothermal gradient provide favorable conditions for the large-scale accumulation of natural gas.展开更多
文摘Objective:To investigate the effect of TSH inhibition therapy in the postoperative management of patients with differentiated thyroid cancer.Methods:Seventy patients diagnosed with differentiated thyroid cancer were selected for the study.TSH inhibition therapy was administered to the research group,while thyroxine replacement therapy was provided to the control group during the postoperative management phase.This allowed for a comparative analysis between the two groups.Results:In comparison with the control group,the research group exhibited significant decreases in serum TSH,T3,and T4 levels after treatment,while FT4 and FT3 levels significantly increased(P<0.05).Additionally,significant decreases in Tg,VEGF,TSGF,CD44V6,and sIL-2R levels were observed in the research group after treatment(P<0.05).No significant differences were found in pre-treatment thyroid function between the two groups(P>0.05).Conclusion:The application of TSH inhibition therapy in the postoperative management of patients with differentiated thyroid cancer demonstrates promising outcomes.
文摘Objective:To analyze the effect of thyroid-stimulating hormone(TSH)suppression therapy on sex hormone levels in patients undergoing postoperative treatment for thyroid cancer.Methods:A total of 40 patients undergoing postoperative thyroid cancer treatment were selected for data analysis.TSH suppression therapy was implemented during the postoperative period.Patients were grouped according to the TSH level:TSH<0.1,0.1≤TSH<0.5,and TSH≥0.5.Results:Among male patients,there were no significant differences in sex hormone levels at different dosing times and TSH levels(P>0.05).For female patients,testosterone levels at different dosing times showed no significant differences under the same circumstances(P>0.05).The comparison of testosterone levels at different TSH levels over 5 years of TSH suppression therapy did not yield significant differences(P>0.05).However,the comparison of testosterone levels within 5 years of TSH suppression therapy yielded significant differences(P<0.05),with the lowest levels observed at 0.1≤TSH<0.5.Conclusion:The use of TSH suppression therapy in postoperative thyroid cancer treatment minimally affects sex hormone levels in male patients.However,it has a significant impact on female patients.Therefore,preoperative sex hormone testing is recommended,and postoperative monitoring should include regular sex hormone testing.
基金the CNOOC Zhanjiang Branch Research Institute for providing the data and funding(No.CCL2019ZJFNO734).
文摘The Yinggehai Basin is a unique NNW-trending petroliferous basin in the northwestern South China Sea.This paper mainly utilized stratigraphic,tectonic and seismic data by characterizing the geological structures and conducting the geo-mechanical analysis to study the formation,evolution and dynamics of the Yinggehai Basin.The study indicates that the Ailaoshan-Truong Son extruded terrane is composed of multiple secondary extruded bodies.The Red River fault zone,located within the Qiangtang-Simao-Yinggehai mantle flow channel and basin zone,experienced transform-type sinistral strike-slip motion before the basin forming stage and formed a NW-trending extruded mantle uplift,which activated the Yinggehai basin.After experiencing the rift depression,fault depression,and fault subsidence,the basin eventually formed large-scale,thick sedimentation features with ideal hydrocarbon-forming conditions at the end of the Miocene.Later,the basin dynamically transformed and entered a period of tectonic superposition,reworking,and thermal subsidence.Superposition of the NNW thrust sinistral strike-slip fault zone on the northern Hanoi sub-basin complicated the basin structure.Since the Pliocene,the southern Yinggehai main basin has been transformed into an extensional dextral strike-slip environment that hosted numerous mud diapirs.The thin crust and high geothermal gradient provide favorable conditions for the large-scale accumulation of natural gas.
