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Preparation and characterization of a nanostructured lipid carrier for phenylethyl resorcinol
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作者 Danyang Zheng Lihua Cai +4 位作者 Mengyi Xu Shihao Lan Yongchuang Zhu shengzhao gong Wanxian Liang 《Journal of Dermatologic Science and Cosmetic Technology》 2024年第3期20-31,共12页
Phenylethyl resorcinol(PR)demonstrates inhibitory effects on multiple targets in the melanin synthesis pathway,resulting in a strong whitening effect.However,challenges such as limited solubility in water and suscepti... Phenylethyl resorcinol(PR)demonstrates inhibitory effects on multiple targets in the melanin synthesis pathway,resulting in a strong whitening effect.However,challenges such as limited solubility in water and susceptibility to oxidation and discoloration restrict its practical application in the cosmetics industry.In order to enhance stability and performance characteristics,a whitening nanostructured lipid carrier(NLC)was synthesized through high-pressure homogenization.This method entailed the incorporation of solid lipids,a liquid lipid,and a compound emulsifier,with deionized water fulfilling the roles of solid phase,liquid phase,and water phase,respectively.The NLC's particle size,Zeta potential,stability,encapsulation efficiency,and other parameters were assessed using techniques such as particle sizer,stability analyzer,and HPLC.The results showed that the NLC for phenylethyl resorcinol prepared by using the optimal formula(7.50%solid lipids,3.00%ethylhexyl palmitate,and 2.00%Tween 80 and soybean lecithin)has an encapsulation efficiency of 87.11%,a particle size of 157.2±0.70 nm,a kinetic instability of less than 1.2,and a greatly improved stability,thereby successfully solving the problems of unstable storage and poor solubility of phenylethyl resorcinol. 展开更多
关键词 Phenylethyl resorcinol STABILITY Particle size Encapsulation efficiency Nanostructured lipid carrier
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Curriculum Reform Practices in “Cosmetic Product Formulation Design and Preparation Technology” Under the Perspective of Integration of Industry, Education, and Research
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作者 Lei Shi shengzhao gong +1 位作者 Xiao Huang Jiesheng Chen 《Journal of Contemporary Educational Research》 2024年第6期194-201,共8页
With the upgrading of industries,the cosmetics industry has posed new requirements for technical talents.As a professional core course in cosmetic technology,“Cosmetic Product Formulation Design and Preparation Techn... With the upgrading of industries,the cosmetics industry has posed new requirements for technical talents.As a professional core course in cosmetic technology,“Cosmetic Product Formulation Design and Preparation Technology”serves as the foundation for cultivating students’abilities in cosmetic development and preparation.To foster high-quality skilled talents capable of adapting to the rapid growth of color cosmetics and to better promote the deep integration of scientific and technological industries with curriculum teaching,the teacher team embarked on active explorations and practical teaching research for curriculum teaching reform from four dimensions:strengthening top-level design,enriching teaching content,optimizing teaching design,and reforming assessment methods.These efforts have enhanced students’comprehensive vocational qualities and innovative consciousness,contributing to the teaching reform in higher vocational colleges under the integration of industry,education,and research. 展开更多
关键词 Cosmetic Product Formulation Design and Preparation Technology Curriculum teaching reform Integration of industry education and research Cosmetic technology
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表面活性剂与皮肤相互作用的研究进展 被引量:8
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作者 李强 龚盛昭 +1 位作者 万岳鹏 孟潇 《日用化学工业(中英文)》 CAS 北大核心 2023年第1期71-78,共8页
表面活性剂作为个人护理清洁产品的主要清洁成分,会直接接触皮肤进而与皮肤产生不同的作用。表面活性剂对皮肤的刺激性与其结构、类型、浓度、暴露时间、皮肤状态等多种因素相关。在清洁过程中,皮肤表面的污垢被表面活性剂增溶带入水中... 表面活性剂作为个人护理清洁产品的主要清洁成分,会直接接触皮肤进而与皮肤产生不同的作用。表面活性剂对皮肤的刺激性与其结构、类型、浓度、暴露时间、皮肤状态等多种因素相关。在清洁过程中,皮肤表面的污垢被表面活性剂增溶带入水中,表面活性剂也会与细胞间脂质相互作用加剧对皮肤屏障功能的破坏,导致皮肤干燥紧绷。但随着表面活性剂的进一步渗透并迁移到更深的皮层,会对活的表皮细胞如角质形成细胞产生破坏作用,并引起皮肤的局部炎症反应。文章简要概述了表面活性剂在水溶液中的基本性质及其结构与刺激性的联系,对表面活性剂的皮肤渗透理论模型、以及对皮肤脂质和活细胞的影响进行了归纳总结,并从个人护理产品配方角度出发,对表面活性剂降低皮肤刺激性的方法进行了可行性的展望。 展开更多
关键词 表面活性剂 皮肤刺激 角质层 个人护理产品
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不同种类甘草成分及美白抗敏活性差异研究 被引量:7
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作者 张兴琪 何敬愉 +1 位作者 龚盛昭 刘林峰 《日用化学工业》 CAS 北大核心 2021年第7期648-654,共7页
以甘草的3种不同基源植物胀果甘草、光果甘草及甘草为研究对象,比较其成分及活性差异。采用高效液相色谱法测定甘草苷、甘草酸及光甘草定的含量,并进行比较;通过紫外分光法比较3种甘草的总黄酮含量差异,并对酪氨酸酶及透明质酸酶活性抑... 以甘草的3种不同基源植物胀果甘草、光果甘草及甘草为研究对象,比较其成分及活性差异。采用高效液相色谱法测定甘草苷、甘草酸及光甘草定的含量,并进行比较;通过紫外分光法比较3种甘草的总黄酮含量差异,并对酪氨酸酶及透明质酸酶活性抑制进行比较。结果显示,高效液相色谱法的精密度、稳定性、重复性、加样回收率的RSD值均不大于2.09%;含量分析结果表明,甘草酸及光甘草定在光果甘草中含量最高,甘草苷在甘草含量中最高。甘草药材总黄酮含量大小顺序为:光果甘草>甘草>胀果甘草;对酪氨酸酶抑制率大小顺序为:光果甘草>甘草>胀果甘草,IC_(50)值分别为7.36,8.38和11.13 mg/L;对透明质酸酶抑制率大小顺序为:胀果甘草>甘草>光果甘草,IC_(50)值分别为8.70,9.19和10.45 mg/mL。3种甘草对酪氨酸酶及透明质酸酶抑制良好,可能具有较好的美白和抗敏功效,为了达到最佳效果需要区分使用。 展开更多
关键词 甘草 高效液相色谱法 含量测定 总黄酮 美白 抗敏
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基于工科高职院校生的工匠精神培育探讨 被引量:1
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作者 石磊 龚盛昭 +2 位作者 李华 周亮 陈庆生 《广东化工》 CAS 2019年第9期270-271,共2页
工匠精神是一种包含精益求精和勇于创新等特征的职业态度和职业理念。在工科高职教育中培育学生的工匠精神对于提高学生素养和未来职业发展都有着极为重要的意义。本文简要探讨了如何在工科高职教育教学中融入“工匠精神”的方法,意在... 工匠精神是一种包含精益求精和勇于创新等特征的职业态度和职业理念。在工科高职教育中培育学生的工匠精神对于提高学生素养和未来职业发展都有着极为重要的意义。本文简要探讨了如何在工科高职教育教学中融入“工匠精神”的方法,意在实现高职大学生的全方位培养和职业素养的提升。 展开更多
关键词 工匠精神 高职教育 工科高职院校
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Demonstration of the Distinguished Teacher Studio Leads the Exploration and Practice of Teachers’Teaching Innovation Team
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作者 Yongchuang Zhu shengzhao gong 《Journal of Contemporary Educational Research》 2022年第9期10-15,共6页
The work of the distinguished teacher studio is based on activities and has the characteristics of learning,demonstration,and academic.The“double-qualified”distinguished teacher studio is an important way to help th... The work of the distinguished teacher studio is based on activities and has the characteristics of learning,demonstration,and academic.The“double-qualified”distinguished teacher studio is an important way to help the development of vocational education teachers and cultivate outstanding“double-qualified”teachers.It is also an important carrier to improve teachers’teaching,practice,and scientific research ability,to promote the“three education reform”of vocational education,and to train high-quality technical personnel. 展开更多
关键词 Distinguished teacher studio Teacher teaching innovation team School-enterprise cooperation Vocational education
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