Background Racial disparities in cardiovascular conditions are well documented.Whether similar race-based discrepancies in health outcomes also exist among elderly patients undergoing surgical aortic valve replacement...Background Racial disparities in cardiovascular conditions are well documented.Whether similar race-based discrepancies in health outcomes also exist among elderly patients undergoing surgical aortic valve replacement(SAVR) for aortic stenosis remains understudied.Methods We abstracted data from the National(Nationwide) Inpatient Sample over a 20-year period from 2001 to 2020 using specific ICD-9 and ICD-10 codes.We included patients aged ≥ 60 and ≤ 80 years with races recorded as White,African American,or Hispanic at the time of their hospitalization for surgery.We analyzed and reported the baseline characteristics,risk-adjusted inhospital mortality,and complications stratified by race.Results Of 420,181 patients studied,90.0% identified as White,4.0% as African American and 6.0% as Hispanic.Despite a decrease in overall in-hospital mortality rates from 3.8% between 2001-2005 to 1.8% between 2016-2020,African Americans had higher odds of all-cause in-hospital deaths compared to Whites(a OR = 1.390,P < 0.001).Additionally,they were more likely to experience cardiogenic shock(a OR = 1.241,P < 0.001) and acute kidney injury(a OR = 1.314,P < 0.001) as well as more likely to require organ support such as IABP use(a OR = 1.336,P < 0.001) or invasive mechanical ventilation(a OR = 1.342,P < 0.001).Interestingly,African Americans were less likely to report events of acute ischemic stroke compared to Whites(a OR = 0.852,P < 0.001).Conclusions Despite a reassuring reduction in overall in-hospital mortality rates of geriatric patients undergoing SAVR for aortic stenosis,racial disparities in health outcomes remain pervasive with minorities more likely to report higher in-hospital morbidity and mortality.展开更多
This work describes investigation of radiation dosimetry characteristics of magnesium （Mg） doped lithium fluoride （LiF） crystals co-doped with different concentrations of dysprosium （Dy）. These crystals were gro...This work describes investigation of radiation dosimetry characteristics of magnesium （Mg） doped lithium fluoride （LiF） crystals co-doped with different concentrations of dysprosium （Dy）. These crystals were grown by edge defined film fed crystal growth （EFG） tech- nique. Thermoluminescence （TL） measurements were made on as grown （AG） and annealed （AN） crystals after they were irradiated with a gamma dose of 15 Gy. The influence and advantage of optimized Dy^3＋ concentration in enhancing the thermoluminescence （TL） properties of LiF：Mg samples were discussed. The normalized peak height of the annealed crystals was nearly 3 times that of the as grown crystals for the particular concentration samples irradiated with Co6~ gamma source showed linearity up to 10 Gy. Thermoluminescence signal observed over a period of one month showed negligible fading. Thermoluminescence glow curve structure of optimized phosphor remained stable for higher doses of gamma rays of 103 Gy. Glow curve was analyzed using computer glow curve deconvolution （CGCD） method and trapping parame- ters were calculated.展开更多
文摘Background Racial disparities in cardiovascular conditions are well documented.Whether similar race-based discrepancies in health outcomes also exist among elderly patients undergoing surgical aortic valve replacement(SAVR) for aortic stenosis remains understudied.Methods We abstracted data from the National(Nationwide) Inpatient Sample over a 20-year period from 2001 to 2020 using specific ICD-9 and ICD-10 codes.We included patients aged ≥ 60 and ≤ 80 years with races recorded as White,African American,or Hispanic at the time of their hospitalization for surgery.We analyzed and reported the baseline characteristics,risk-adjusted inhospital mortality,and complications stratified by race.Results Of 420,181 patients studied,90.0% identified as White,4.0% as African American and 6.0% as Hispanic.Despite a decrease in overall in-hospital mortality rates from 3.8% between 2001-2005 to 1.8% between 2016-2020,African Americans had higher odds of all-cause in-hospital deaths compared to Whites(a OR = 1.390,P < 0.001).Additionally,they were more likely to experience cardiogenic shock(a OR = 1.241,P < 0.001) and acute kidney injury(a OR = 1.314,P < 0.001) as well as more likely to require organ support such as IABP use(a OR = 1.336,P < 0.001) or invasive mechanical ventilation(a OR = 1.342,P < 0.001).Interestingly,African Americans were less likely to report events of acute ischemic stroke compared to Whites(a OR = 0.852,P < 0.001).Conclusions Despite a reassuring reduction in overall in-hospital mortality rates of geriatric patients undergoing SAVR for aortic stenosis,racial disparities in health outcomes remain pervasive with minorities more likely to report higher in-hospital morbidity and mortality.
基金Project supported by the Department of Science & Technology Project (SR/NM/NAT-02-2007)
文摘This work describes investigation of radiation dosimetry characteristics of magnesium （Mg） doped lithium fluoride （LiF） crystals co-doped with different concentrations of dysprosium （Dy）. These crystals were grown by edge defined film fed crystal growth （EFG） tech- nique. Thermoluminescence （TL） measurements were made on as grown （AG） and annealed （AN） crystals after they were irradiated with a gamma dose of 15 Gy. The influence and advantage of optimized Dy^3＋ concentration in enhancing the thermoluminescence （TL） properties of LiF：Mg samples were discussed. The normalized peak height of the annealed crystals was nearly 3 times that of the as grown crystals for the particular concentration samples irradiated with Co6~ gamma source showed linearity up to 10 Gy. Thermoluminescence signal observed over a period of one month showed negligible fading. Thermoluminescence glow curve structure of optimized phosphor remained stable for higher doses of gamma rays of 103 Gy. Glow curve was analyzed using computer glow curve deconvolution （CGCD） method and trapping parame- ters were calculated.
