硅是植物生长的有益元素,也是人和其他动物生长发育、骨骼形成不可或缺的微量元素。在地球表层系统中,大多数的硅以硅酸盐矿物和石英的形式赋存于岩石之中。伴随着地表硅酸盐矿物的风化,硅可以水为载体不断向周边环境释放并参与到生物...硅是植物生长的有益元素,也是人和其他动物生长发育、骨骼形成不可或缺的微量元素。在地球表层系统中,大多数的硅以硅酸盐矿物和石英的形式赋存于岩石之中。伴随着地表硅酸盐矿物的风化,硅可以水为载体不断向周边环境释放并参与到生物地球化学循环中,为陆地和海洋生物提供所需的硅元素,维持生态系统健康,在全球物质循环中起着重要作用(Yang Jinling et al.,2018)。展开更多
The projectile penetration process into concrete target is a nonlinear complex problem.With the increase ofexperiment data,the data-driven paradigm has exhibited a new feasible method to solve such complex prob-lem.Ho...The projectile penetration process into concrete target is a nonlinear complex problem.With the increase ofexperiment data,the data-driven paradigm has exhibited a new feasible method to solve such complex prob-lem.However,due to poor quality of experimental data,the traditional machine learning(ML)methods,whichare driven only by experimental data,have poor generalization capabilities and limited prediction accuracy.Therefore,this study intends to exhibit a ML method fusing the prior knowledge with experiment data.The newML method can constrain the fitting to experimental data,improve the generalization ability and the predic-tion accuracy.Experimental results show that integrating domain prior knowledge can effectively improve theperformance of the prediction model for penetration depth into concrete targets.展开更多
Introduction:Plague is a zoonotic disease that occurs naturally in specific geographic areas.Climate change can influence the populations of the plague host or vector,leading to variations in the occurrence and epidem...Introduction:Plague is a zoonotic disease that occurs naturally in specific geographic areas.Climate change can influence the populations of the plague host or vector,leading to variations in the occurrence and epidemiology of plague in animals.Methods:In this study,we collected meteorological and plague epidemiological data from the Marmota himalayana plague focus in the Altun Mountains of the Qinghai-Xizang Plateau.The data spanned from 2000 to 2022.We describe the climatic factors and plague epidemic conditions and we describe their analysis by Pearson’s correlation.Results:During the period from 2000 to 2022,the isolation rates of Yersinia pestis(Y.pestis)from marmots and fleas were 9.27%(451/4,864)and 7.17%(118/1,646),respectively.Additionally,we observed a positive rate of F1 antibody of 11.25%(443/3,937)in marmots and 18.16%(142/782)in dogs.With regards to climate,there was little variation,and a decreasing trend in blowing-sand days was observed.The temperature in the previous year showed a negative correlation with the Y.pestis isolation rate in marmots(r=−0.555,P=0.011)and the positive rate of F1 antibody in marmots(r=−0.552,P=0.012)in the current year.The average annual precipitation in the previous two years showed a positive correlation with marmot density(r=0.514,P=0.024),while blowingsand days showed a negative correlation with marmot density(r=−0.701,P=0.001).Furthermore,the average annual precipitation in the previous three years showed a positive correlation with the isolation rate of Y.pestis from marmots(r=0.666,P=0.003),and blowing-sand days showed a negative correlation with marmot density(r=−0.597,P=0.009).Conclusions:The findings of this study indicate that there is a hysteresis effect of climate change on the prevalence of plague.Therefore,monitoring climate conditions can offer significant insights for implementing timely preventive and control measures to combat plague epidemics.展开更多
Intense investigations have been attracted to the development of materials which can recon-figure into 3D structures in response to external stimuli.Herein we report on the design and self-folding behaviors of hydroge...Intense investigations have been attracted to the development of materials which can recon-figure into 3D structures in response to external stimuli.Herein we report on the design and self-folding behaviors of hydrogels composed of poly(ethylene glycol)methyl ether methacry-late(OEGMA)and 2-(2-methoxyethoxy)ethyl methacrylate(MEO2MA).Upon immersion into a variety of solvents at room temperature,the resulting P(MEO2MA-co-OEGMA)hy-drogel sheets self-fold into 3D morphologies,and the observed transformation in shape is reversible.We further show that composition of the gel,gaseous environment,and prepara-tion procedure play important roles in the self-folding behavior of the resulting hydrogels.This work provides a facile approach for fabricating self-folding hydrogels.展开更多
A flow injection (FI) micro-column system coupled with high performance liquid chromatography (HPLC) was proposed for the pre-separation and determination of active organic component (ecdysterone) in traditional Chine...A flow injection (FI) micro-column system coupled with high performance liquid chromatography (HPLC) was proposed for the pre-separation and determination of active organic component (ecdysterone) in traditional Chinese medicine, Loulu. The factors influencing separation performance were investigated and optimized. Under the optimal conditions, the contents of ecdysterone in Loulu were determined by HPLC system using MeOH-H_2O (40: 60,V/V) as the mobile phase at a flow rate of 1. 0 mL/min. The calibration curve was linear in the range of 0. 5~ 100 mg/L of ecdysterone concentrations. The detection limit of the analyte was 0. 11mol/L(3) with a precision of 0. 38% RSD (n=7 f c= 10. 0 mg/L). The average recovery of the method was 98. 7%. The proposed method has been applied to determine ecdysterone in practical samples, and the determined values by both external standard method and standard addition method were in good agreement. Compared to the traditional solid extraction method, the system proposed has the advantages of simple procedure, good reproducibility, minimum volume requirement, reduction of matrix interference and low contamination risk.展开更多
The multi-electron capture and loss cross-sections of Ar^(+)-Ne collisions are calculated at absolute energies in the few-keV/a.u.regime.The calculations are performed using a novel inverse collision framework,in the ...The multi-electron capture and loss cross-sections of Ar^(+)-Ne collisions are calculated at absolute energies in the few-keV/a.u.regime.The calculations are performed using a novel inverse collision framework,in the context of a time-dependent density functional theory,combined with molecular dynamics.The extraction of the capture and loss probabilities is based on the particle-number projection technique,originating from nuclear physics,but validly extended to represent many-electron systems.Good agreement between experimental and theoretical data is found,which clearly reveals the non-negligible post-collision decay of the projectile’s electrons,providing further evidence for the applicability of the approach to complex many-electron collision systems.展开更多
Summary What is already known about this topic?The prevalence of rodent-adapted Bartonella species has been increasing significantly.However,the specific Bartonella species carried by Marmota himalayana(M.himalayana),...Summary What is already known about this topic?The prevalence of rodent-adapted Bartonella species has been increasing significantly.However,the specific Bartonella species carried by Marmota himalayana(M.himalayana),a large rodent species,and the potential risk it poses to human populations remain unknown.What is added by this report?Bartonella washoensis(B.washoensis),associated with human endocarditis,was initially identified in M.himalayana,exhibiting a detection rate of approximately one-third and demonstrating a predilection for the heart and lungs.The discovery of the novel Sequence Type 22 has expanded both the isolation source and genetic lineage of B.washoensis.What are the implications for public health practice?Individuals residing within the M.himalayana plague focus are at an elevated risk for B.washoensis infection.Consequently,there is a pressing need for public health warnings and efficient clinical case identification in this population.展开更多
Summary What is already known about this topic?The hospital-acquired infections caused by New Delhi metallo-beta-lactamase(NDM)-producing strains are typically attributed to a single clonal lineage.What is added by th...Summary What is already known about this topic?The hospital-acquired infections caused by New Delhi metallo-beta-lactamase(NDM)-producing strains are typically attributed to a single clonal lineage.What is added by this report?In this study,we encountered a unique case of community-acquired NDM-5 Escherichia coli urinary tract infection(UTI)following coronavirus disease 2019(COVID-19).The UTI persisted for a duration of at least 45 days.Genomic analyses revealed the presence of two NDM-5 strains,both sharing an identical chromosomal background but distinct,homologous,and recombined plasmids.展开更多
文摘硅是植物生长的有益元素,也是人和其他动物生长发育、骨骼形成不可或缺的微量元素。在地球表层系统中,大多数的硅以硅酸盐矿物和石英的形式赋存于岩石之中。伴随着地表硅酸盐矿物的风化,硅可以水为载体不断向周边环境释放并参与到生物地球化学循环中,为陆地和海洋生物提供所需的硅元素,维持生态系统健康,在全球物质循环中起着重要作用(Yang Jinling et al.,2018)。
基金supported by the National Natural Science Founda-tion of China(Grant No.12172381)Leading Talents of Science and Technology in the Central Plain of China(Grant No.234200510016).
文摘The projectile penetration process into concrete target is a nonlinear complex problem.With the increase ofexperiment data,the data-driven paradigm has exhibited a new feasible method to solve such complex prob-lem.However,due to poor quality of experimental data,the traditional machine learning(ML)methods,whichare driven only by experimental data,have poor generalization capabilities and limited prediction accuracy.Therefore,this study intends to exhibit a ML method fusing the prior knowledge with experiment data.The newML method can constrain the fitting to experimental data,improve the generalization ability and the predic-tion accuracy.Experimental results show that integrating domain prior knowledge can effectively improve theperformance of the prediction model for penetration depth into concrete targets.
基金Supported by the National Key Research and Development Program of China(2022YFC2602203).
文摘Introduction:Plague is a zoonotic disease that occurs naturally in specific geographic areas.Climate change can influence the populations of the plague host or vector,leading to variations in the occurrence and epidemiology of plague in animals.Methods:In this study,we collected meteorological and plague epidemiological data from the Marmota himalayana plague focus in the Altun Mountains of the Qinghai-Xizang Plateau.The data spanned from 2000 to 2022.We describe the climatic factors and plague epidemic conditions and we describe their analysis by Pearson’s correlation.Results:During the period from 2000 to 2022,the isolation rates of Yersinia pestis(Y.pestis)from marmots and fleas were 9.27%(451/4,864)and 7.17%(118/1,646),respectively.Additionally,we observed a positive rate of F1 antibody of 11.25%(443/3,937)in marmots and 18.16%(142/782)in dogs.With regards to climate,there was little variation,and a decreasing trend in blowing-sand days was observed.The temperature in the previous year showed a negative correlation with the Y.pestis isolation rate in marmots(r=−0.555,P=0.011)and the positive rate of F1 antibody in marmots(r=−0.552,P=0.012)in the current year.The average annual precipitation in the previous two years showed a positive correlation with marmot density(r=0.514,P=0.024),while blowingsand days showed a negative correlation with marmot density(r=−0.701,P=0.001).Furthermore,the average annual precipitation in the previous three years showed a positive correlation with the isolation rate of Y.pestis from marmots(r=0.666,P=0.003),and blowing-sand days showed a negative correlation with marmot density(r=−0.597,P=0.009).Conclusions:The findings of this study indicate that there is a hysteresis effect of climate change on the prevalence of plague.Therefore,monitoring climate conditions can offer significant insights for implementing timely preventive and control measures to combat plague epidemics.
基金supported by the Youth Innovation Promotion Association of Chinese Academy of Sciences
文摘Intense investigations have been attracted to the development of materials which can recon-figure into 3D structures in response to external stimuli.Herein we report on the design and self-folding behaviors of hydrogels composed of poly(ethylene glycol)methyl ether methacry-late(OEGMA)and 2-(2-methoxyethoxy)ethyl methacrylate(MEO2MA).Upon immersion into a variety of solvents at room temperature,the resulting P(MEO2MA-co-OEGMA)hy-drogel sheets self-fold into 3D morphologies,and the observed transformation in shape is reversible.We further show that composition of the gel,gaseous environment,and prepara-tion procedure play important roles in the self-folding behavior of the resulting hydrogels.This work provides a facile approach for fabricating self-folding hydrogels.
基金Education Ministy Foundation for Chinese Returned Scholars and Nature Science Foundation of Hubeiprovince!98J054
文摘A flow injection (FI) micro-column system coupled with high performance liquid chromatography (HPLC) was proposed for the pre-separation and determination of active organic component (ecdysterone) in traditional Chinese medicine, Loulu. The factors influencing separation performance were investigated and optimized. Under the optimal conditions, the contents of ecdysterone in Loulu were determined by HPLC system using MeOH-H_2O (40: 60,V/V) as the mobile phase at a flow rate of 1. 0 mL/min. The calibration curve was linear in the range of 0. 5~ 100 mg/L of ecdysterone concentrations. The detection limit of the analyte was 0. 11mol/L(3) with a precision of 0. 38% RSD (n=7 f c= 10. 0 mg/L). The average recovery of the method was 98. 7%. The proposed method has been applied to determine ecdysterone in practical samples, and the determined values by both external standard method and standard addition method were in good agreement. Compared to the traditional solid extraction method, the system proposed has the advantages of simple procedure, good reproducibility, minimum volume requirement, reduction of matrix interference and low contamination risk.
基金Supported by the National Key Research and Development Program of China(Grant No.2017YFA0402300)the National Natural Science Foundation of China(Grant Nos.11774344,11704039,11774030,and 11704037)。
文摘The multi-electron capture and loss cross-sections of Ar^(+)-Ne collisions are calculated at absolute energies in the few-keV/a.u.regime.The calculations are performed using a novel inverse collision framework,in the context of a time-dependent density functional theory,combined with molecular dynamics.The extraction of the capture and loss probabilities is based on the particle-number projection technique,originating from nuclear physics,but validly extended to represent many-electron systems.Good agreement between experimental and theoretical data is found,which clearly reveals the non-negligible post-collision decay of the projectile’s electrons,providing further evidence for the applicability of the approach to complex many-electron collision systems.
基金Supported by the National Key Research and Development Program of China(2022YFC2602203).
文摘Summary What is already known about this topic?The prevalence of rodent-adapted Bartonella species has been increasing significantly.However,the specific Bartonella species carried by Marmota himalayana(M.himalayana),a large rodent species,and the potential risk it poses to human populations remain unknown.What is added by this report?Bartonella washoensis(B.washoensis),associated with human endocarditis,was initially identified in M.himalayana,exhibiting a detection rate of approximately one-third and demonstrating a predilection for the heart and lungs.The discovery of the novel Sequence Type 22 has expanded both the isolation source and genetic lineage of B.washoensis.What are the implications for public health practice?Individuals residing within the M.himalayana plague focus are at an elevated risk for B.washoensis infection.Consequently,there is a pressing need for public health warnings and efficient clinical case identification in this population.
基金Supported by the National Key Research and Development Program of China(2022YFC2602203).
文摘Summary What is already known about this topic?The hospital-acquired infections caused by New Delhi metallo-beta-lactamase(NDM)-producing strains are typically attributed to a single clonal lineage.What is added by this report?In this study,we encountered a unique case of community-acquired NDM-5 Escherichia coli urinary tract infection(UTI)following coronavirus disease 2019(COVID-19).The UTI persisted for a duration of at least 45 days.Genomic analyses revealed the presence of two NDM-5 strains,both sharing an identical chromosomal background but distinct,homologous,and recombined plasmids.
