BACKGROUND With advancements in the development of endoscopic technologies,the endo-scopic submucosal dissection(ESD)has been one of the gold-standard therapies for early gastric cancer.AIM To investigate the efficacy...BACKGROUND With advancements in the development of endoscopic technologies,the endo-scopic submucosal dissection(ESD)has been one of the gold-standard therapies for early gastric cancer.AIM To investigate the efficacy and safety ESD in the treatment of early gastric cancer and precancerous lesions in the elderly patients.METHODS Seventy-eight elderly patients with early gastric cancer and precancerous lesions admitted to the Third Affiliated Hospital of Qiqihar Medical University were se-lected and classified into two groups according to the different surgical therapies they received between January 2021 and June 2022.Among them,39 patients treated with ESD were included in an experimental group,and 39 patients treated with endoscopic mucosal resection(EMR)were included in a control group.We compared the basic intraoperative conditions,postoperative short-term recovery,long-term recovery effects and functional status of gastric mucosa between the two groups;the basic intraoperative conditions included lesion resection,intra-operative bleeding and operation time;the postoperative short-term recovery assessment indexes were length of hospital stay and incidence of surgical complic-ations;and the long-term recovery assessment indexes were the recurrence rate at 1 year postoperatively and the survival situation at 1 year and 3 years postoper-atively;and we compared the preoperative and predischarge serum pepsinogen I(PG I)and PG II levels and PG I/PG II ratio in the two groups before surgery and discharge.RESULTS The curative resection rate and the rate of en bloc resection were higher in the experimental group than in the control group.The intraoperative bleeding volume was higher in the experimental group than in the control group.The operation time was longer in the experimental group than that in the control group,and the rate for base residual focus was lower in the experimental group than that of the control group,and the differences were all statistically significant(all P<0.05).The length of hospital stay was longer in the experi-mental group than in the control group,and the incidence of surgical complications,1-year postoperative recu-rrence rate and 3-year postoperative survival rate were lower in the experimental group than in the control group,and the differences were statistically significant(all P<0.05).However,the difference in the 1-year postoperative survival rate was not statistically significant between the two groups(P>0.05).Before discharge,PG I and PG I/PG II ratio were elevated in both groups compared with the preoperative period,and the above indexes were higher in the experimental group than those in the control group,and the differences were statistically significant(both P<0.05).Moreover,before discharge,PG II level was lower in both groups compared with the preoperative period,and the level was lower in the experimental group than in the control group,and the differences were all statistically significant(all P<0.05).CONCLUSION Compared with EMR,ESD surgery is more thorough.It reduces the rate of base residual focus,recurrence rate,surgical complications,and promotes the recovery of gastric cells and glandular function.It is safe and suitable for clinical application.展开更多
BACKGROUND The incidence of cholelithiasis has been on the rise in recent years,but the choice of procedure is controversial.AIM To investigate the efficacy of laparoscopic cholecystectomy(LC)combined with endoscopic ...BACKGROUND The incidence of cholelithiasis has been on the rise in recent years,but the choice of procedure is controversial.AIM To investigate the efficacy of laparoscopic cholecystectomy(LC)combined with endoscopic papillary balloon dilation(EPBD)in patients with gallbladder stones(GS)with common bile duct stones(CBDS).METHODS The clinical data of 102 patients with GS combined with CBDS were selected for retrospective analysis and divided into either an LC+EPBD group(n=50)or an LC+endoscopic sphincterotomy(EST)group(n=52)according to surgical methods.Surgery-related indexes,postoperative recovery,postoperative complications,and expression levels of inflammatory response indexes were compared between the two groups.RESULTS Total surgical time,stone free rate,rate of conversion to laparotomy,and successful stone extraction rate did not differ significantly between the LC+EPBD group and LC+EST group.Intraoperative hemorrhage,time to ambulation,and length of hospitalization in the LC+EPBD group were lower than those of the LC+EST group(P<0.05).The rate of total complications of the two groups was 9.80%and 17.65%,respectively,and the difference was not statistically significant.No serious complications occurred in either group.At 48 h postoperatively,the expression levels of interleukin-6,tumor necrosis factor-α,high-sensitivity Creactive protein,and procalcitonin were lower in the LC+EPBD group than in the LC+EST group(P<0.05).At 3 d postoperatively,the expression levels of aspartate transaminase,alanine transaminase,and total bilirubin were lower in the LC+EPBD group than in the LC+EST group(P<0.05).CONCLUSION LC combined with EPBD and LC combined with EST are both effective procedures for the treatment of GS with CBDS,in which LC combined with EPBD is beneficial to shorten the patient’s hospitalization time,reduce the magnitude of elevated inflammatory response indexes,and promote postoperative recovery.展开更多
The degree and scale of underground space development are growing with the continuous advancement of urbanization in China.The lack of research on the change of the groundwater flow field before and after the developm...The degree and scale of underground space development are growing with the continuous advancement of urbanization in China.The lack of research on the change of the groundwater flow field before and after the development of underground space has led to various problems in the process of underground space development and operation.This paper took the key development zone of the Xiong’an New Area as the study area,and used the Groundwater modeling system software(GMS)to analyse the influence on the groundwater flow field under the point,line,and surface development modes.The main results showed that the underground space development would lead to the expansion and deepening of the cone of depression in the aquifer.The groundwater level on the upstream face of the underground structure would rise,while the water level on the downstream face would drop.The“line”concurrent development has the least impact on the groundwater flow field,and the maximum rise of water level on the upstream side of the underground structure is expected to be approximately 3.05 m.The“surface”development has the greatest impact on the groundwater flow field,and the maximum rise of water level is expected to be 7.17 m.展开更多
The plastic cement belongs to a sort of polymer material, the chemical composition is very complex, and the plastic cement work-piece is generally manufactured by die press forming. Aimed at being difficult to control...The plastic cement belongs to a sort of polymer material, the chemical composition is very complex, and the plastic cement work-piece is generally manufactured by die press forming. Aimed at being difficult to control in parameters of forming process, the paper explored the humanoid based intelligence control strategy. In the paper, it made the anatomy in control puzzle resulted in uncertainty such as chemical component of plastic cement etc., summarized up the characteristic of cybernetics in forming process, researched on the humanoid based intelligence control strategy, and constructed the control algorithm of forming process in plastic cement work-piece. Taking the process experiment of temperature and pressure control as an example, it validated the good dynamic and static control quality through simulation of control algorithm constructed in this paper. The experimental results show that the control algorithm explored in this paper is reasonably available.展开更多
[Objectives]To investigate the efficacy of Anshen Jieyu decoction for sub-healthy people with insomnia.[Methods]A total of 80 sub-healthy insomnia patients admitted to Taihe Hospital of Shiyan City from January,2020 t...[Objectives]To investigate the efficacy of Anshen Jieyu decoction for sub-healthy people with insomnia.[Methods]A total of 80 sub-healthy insomnia patients admitted to Taihe Hospital of Shiyan City from January,2020 to December,2020 were selected as the research objects.All the patients were divided into observation group and control group according to a random number table.The control group was treated with conventional Western medicine,and the observation group was treated with Anshen Jieyu decoction.The clinical treatment effect of the two groups was compared.[Results]Before the intervention,there was no significant difference in Pittsburgh sleep quality index between the two groups.After the intervention,the scores of time required to fall asleep[(1.2±0.3)points],sleep time[(1.2±0.4)points],sleep disorder[(1.2±0.2)points],sleep efficiency[(1.4±0.3 points)],sleep quality[(0.9±0.2)points]and daytime dysfunction[(0.9±0.4)points]of the observation group were significantly lower than those of the control group.There was no significant difference in life quality between the two groups before the intervention.The scores of physical function[(92.3±3.3)points],social function[(91.7±4.1)points],mental health[(92.3±4.1)points]and emotional role[(92.8±5.2)points]after the intervention were significantly higher than those before the intervention.Before the intervention,there was no significant difference in the severity of insomnia between the two groups.After the intervention,the score of insomnia severity index was(10.3±3.0)points in the observation group and was(12.2±2.9)points in the control group.In terms of safety,there were 23 cases of level 1,15 cases of level 2 and 2 cases of level 3 in the observation group,and there were 20 cases of level 1,16 cases of level 2 and 4 cases of level 3 in the control group.No significant difference was observed in treatment safety between the two groups.[Conclusions]Anshen Jieyu decoction is effective in treating sub-healthy insomnia and is worthy of promotion.展开更多
This study makes an attempt to investigate through statistical analysis the correlation between changes in ice volume and area of glaciers. Using data from nine sample glaciers in the Tian Shan, the results show that ...This study makes an attempt to investigate through statistical analysis the correlation between changes in ice volume and area of glaciers. Using data from nine sample glaciers in the Tian Shan, the results show that a linear relation exists between changes in ice volume and area, with a correlation coefficient of 0.700. However, the accuracy estimation is difficult due to the limited number of samples. The correlation was not improved after adding eleven glacier samples in other mountains. Two reference glaciers are then analyzed in more detail. The linear correlation coefficient is higher than 0.800 when using the observed changes in ice volume and area during different periods on Urumqi Glacier No. 1, which suggests that the linear relation is valid for one glacier for different periods if its shape does not change noticeably and also for other glaciers of the same shape during the same period. The relation between changes in ice volume and area of Qingbingtan Glacier No. 72 is different during different periods due to change in the shape of the glacier tongue and the influence of the debris cover. Moreover, errors in glacier-change monitoring and-volume estimation have an important influence on the correlation results. Therefore, further study needs to focus not only on the distinction between glacier types and between different periods but also on the accuracy of volume estimation.展开更多
Aerosol samples were collected at altitudes from 584 m a.s.l.to 3,804 m a.s.l.at seven sites of the eastern Tianshan.The occurrence,distribution,and possible sources of 47 trace metals—including alkali metals and alk...Aerosol samples were collected at altitudes from 584 m a.s.l.to 3,804 m a.s.l.at seven sites of the eastern Tianshan.The occurrence,distribution,and possible sources of 47 trace metals—including alkali metals and alkali earth metals,transition metals,lanthanoids,and heavy metals—were investigated.It was found that four sampling sites(Shuinichang,1,691 m a.s.l.;Urumqi City,809 m a.s.l.;Fu Kang Station,584 m a.s.l.;and Bogeda Glacier No.4,3,613 m a.s.l.)were contaminated mainly by heavy metals.Other three high-altitude sites(Urumqi Glacier No.1,3,804 m a.s.l.;Wang Feng road-maintenance station,3,039 m a.s.l.;and Tianshan Glaciology Station,2,135 m a.s.l.)were not polluted.The aerosol particles were clustered into two dominant types:crust-originated particles and pollution-derived particles.Aerosols from UG1,WF,and TGS were characterized by crust-originated particles such as clay,plagioclase,dolomite,alkali feldspar,and biotite;while those from SNC,Urumqi,FK,and BG4 were characterized by high content of Cl-rich particles,S-rich particles,and soot.The backward-trajectories results indicated that air masses arriving at SNC,Urumqi,FK,and BG4 were identified as the more polluted source,when compared to the short-range air mass transport from the North to UGI and WF.Relatively lower altitude,as well as terrain blocking,might be another important reason for the gradient difference in pollution influence among these seven places in the Urumqi River Basin.展开更多
基金Supported by Qiqihar Scientific and Technological Plan Joint Guidance Projects,No.LSFGG-2023015.
文摘BACKGROUND With advancements in the development of endoscopic technologies,the endo-scopic submucosal dissection(ESD)has been one of the gold-standard therapies for early gastric cancer.AIM To investigate the efficacy and safety ESD in the treatment of early gastric cancer and precancerous lesions in the elderly patients.METHODS Seventy-eight elderly patients with early gastric cancer and precancerous lesions admitted to the Third Affiliated Hospital of Qiqihar Medical University were se-lected and classified into two groups according to the different surgical therapies they received between January 2021 and June 2022.Among them,39 patients treated with ESD were included in an experimental group,and 39 patients treated with endoscopic mucosal resection(EMR)were included in a control group.We compared the basic intraoperative conditions,postoperative short-term recovery,long-term recovery effects and functional status of gastric mucosa between the two groups;the basic intraoperative conditions included lesion resection,intra-operative bleeding and operation time;the postoperative short-term recovery assessment indexes were length of hospital stay and incidence of surgical complic-ations;and the long-term recovery assessment indexes were the recurrence rate at 1 year postoperatively and the survival situation at 1 year and 3 years postoper-atively;and we compared the preoperative and predischarge serum pepsinogen I(PG I)and PG II levels and PG I/PG II ratio in the two groups before surgery and discharge.RESULTS The curative resection rate and the rate of en bloc resection were higher in the experimental group than in the control group.The intraoperative bleeding volume was higher in the experimental group than in the control group.The operation time was longer in the experimental group than that in the control group,and the rate for base residual focus was lower in the experimental group than that of the control group,and the differences were all statistically significant(all P<0.05).The length of hospital stay was longer in the experi-mental group than in the control group,and the incidence of surgical complications,1-year postoperative recu-rrence rate and 3-year postoperative survival rate were lower in the experimental group than in the control group,and the differences were statistically significant(all P<0.05).However,the difference in the 1-year postoperative survival rate was not statistically significant between the two groups(P>0.05).Before discharge,PG I and PG I/PG II ratio were elevated in both groups compared with the preoperative period,and the above indexes were higher in the experimental group than those in the control group,and the differences were statistically significant(both P<0.05).Moreover,before discharge,PG II level was lower in both groups compared with the preoperative period,and the level was lower in the experimental group than in the control group,and the differences were all statistically significant(all P<0.05).CONCLUSION Compared with EMR,ESD surgery is more thorough.It reduces the rate of base residual focus,recurrence rate,surgical complications,and promotes the recovery of gastric cells and glandular function.It is safe and suitable for clinical application.
基金Supported by Qiqihar Science and Technology Plan Joint Guidance Project,No.LHYD-2021058.
文摘BACKGROUND The incidence of cholelithiasis has been on the rise in recent years,but the choice of procedure is controversial.AIM To investigate the efficacy of laparoscopic cholecystectomy(LC)combined with endoscopic papillary balloon dilation(EPBD)in patients with gallbladder stones(GS)with common bile duct stones(CBDS).METHODS The clinical data of 102 patients with GS combined with CBDS were selected for retrospective analysis and divided into either an LC+EPBD group(n=50)or an LC+endoscopic sphincterotomy(EST)group(n=52)according to surgical methods.Surgery-related indexes,postoperative recovery,postoperative complications,and expression levels of inflammatory response indexes were compared between the two groups.RESULTS Total surgical time,stone free rate,rate of conversion to laparotomy,and successful stone extraction rate did not differ significantly between the LC+EPBD group and LC+EST group.Intraoperative hemorrhage,time to ambulation,and length of hospitalization in the LC+EPBD group were lower than those of the LC+EST group(P<0.05).The rate of total complications of the two groups was 9.80%and 17.65%,respectively,and the difference was not statistically significant.No serious complications occurred in either group.At 48 h postoperatively,the expression levels of interleukin-6,tumor necrosis factor-α,high-sensitivity Creactive protein,and procalcitonin were lower in the LC+EPBD group than in the LC+EST group(P<0.05).At 3 d postoperatively,the expression levels of aspartate transaminase,alanine transaminase,and total bilirubin were lower in the LC+EPBD group than in the LC+EST group(P<0.05).CONCLUSION LC combined with EPBD and LC combined with EST are both effective procedures for the treatment of GS with CBDS,in which LC combined with EPBD is beneficial to shorten the patient’s hospitalization time,reduce the magnitude of elevated inflammatory response indexes,and promote postoperative recovery.
基金the Evaluation of soil and water quality and engineering geological survey in Xiong’an New Area Program of China(Grant No.DD20189122)National Natural Science Foundation of China(Grant No.42102294).
文摘The degree and scale of underground space development are growing with the continuous advancement of urbanization in China.The lack of research on the change of the groundwater flow field before and after the development of underground space has led to various problems in the process of underground space development and operation.This paper took the key development zone of the Xiong’an New Area as the study area,and used the Groundwater modeling system software(GMS)to analyse the influence on the groundwater flow field under the point,line,and surface development modes.The main results showed that the underground space development would lead to the expansion and deepening of the cone of depression in the aquifer.The groundwater level on the upstream face of the underground structure would rise,while the water level on the downstream face would drop.The“line”concurrent development has the least impact on the groundwater flow field,and the maximum rise of water level on the upstream side of the underground structure is expected to be approximately 3.05 m.The“surface”development has the greatest impact on the groundwater flow field,and the maximum rise of water level is expected to be 7.17 m.
文摘The plastic cement belongs to a sort of polymer material, the chemical composition is very complex, and the plastic cement work-piece is generally manufactured by die press forming. Aimed at being difficult to control in parameters of forming process, the paper explored the humanoid based intelligence control strategy. In the paper, it made the anatomy in control puzzle resulted in uncertainty such as chemical component of plastic cement etc., summarized up the characteristic of cybernetics in forming process, researched on the humanoid based intelligence control strategy, and constructed the control algorithm of forming process in plastic cement work-piece. Taking the process experiment of temperature and pressure control as an example, it validated the good dynamic and static control quality through simulation of control algorithm constructed in this paper. The experimental results show that the control algorithm explored in this paper is reasonably available.
基金Supported by Project of Taihe Hospital of Shiyan City(2019JJXM099).
文摘[Objectives]To investigate the efficacy of Anshen Jieyu decoction for sub-healthy people with insomnia.[Methods]A total of 80 sub-healthy insomnia patients admitted to Taihe Hospital of Shiyan City from January,2020 to December,2020 were selected as the research objects.All the patients were divided into observation group and control group according to a random number table.The control group was treated with conventional Western medicine,and the observation group was treated with Anshen Jieyu decoction.The clinical treatment effect of the two groups was compared.[Results]Before the intervention,there was no significant difference in Pittsburgh sleep quality index between the two groups.After the intervention,the scores of time required to fall asleep[(1.2±0.3)points],sleep time[(1.2±0.4)points],sleep disorder[(1.2±0.2)points],sleep efficiency[(1.4±0.3 points)],sleep quality[(0.9±0.2)points]and daytime dysfunction[(0.9±0.4)points]of the observation group were significantly lower than those of the control group.There was no significant difference in life quality between the two groups before the intervention.The scores of physical function[(92.3±3.3)points],social function[(91.7±4.1)points],mental health[(92.3±4.1)points]and emotional role[(92.8±5.2)points]after the intervention were significantly higher than those before the intervention.Before the intervention,there was no significant difference in the severity of insomnia between the two groups.After the intervention,the score of insomnia severity index was(10.3±3.0)points in the observation group and was(12.2±2.9)points in the control group.In terms of safety,there were 23 cases of level 1,15 cases of level 2 and 2 cases of level 3 in the observation group,and there were 20 cases of level 1,16 cases of level 2 and 4 cases of level 3 in the control group.No significant difference was observed in treatment safety between the two groups.[Conclusions]Anshen Jieyu decoction is effective in treating sub-healthy insomnia and is worthy of promotion.
基金funded by the National Natural Science Foundation of China (41771077)the Funds for Creative Research Groups of China (41421061)+1 种基金the Strategic Priority Research Program of Chinese Acad emy of Sciences (XDA20020102)the Youth Innovation Promotion Association of CAS
文摘This study makes an attempt to investigate through statistical analysis the correlation between changes in ice volume and area of glaciers. Using data from nine sample glaciers in the Tian Shan, the results show that a linear relation exists between changes in ice volume and area, with a correlation coefficient of 0.700. However, the accuracy estimation is difficult due to the limited number of samples. The correlation was not improved after adding eleven glacier samples in other mountains. Two reference glaciers are then analyzed in more detail. The linear correlation coefficient is higher than 0.800 when using the observed changes in ice volume and area during different periods on Urumqi Glacier No. 1, which suggests that the linear relation is valid for one glacier for different periods if its shape does not change noticeably and also for other glaciers of the same shape during the same period. The relation between changes in ice volume and area of Qingbingtan Glacier No. 72 is different during different periods due to change in the shape of the glacier tongue and the influence of the debris cover. Moreover, errors in glacier-change monitoring and-volume estimation have an important influence on the correlation results. Therefore, further study needs to focus not only on the distinction between glacier types and between different periods but also on the accuracy of volume estimation.
基金supported by the National Natural Science Foundation of China (41201065 41121001, 41261017, 41171057, 41161012)the Funds for Creative Research Groups of China (41121001)+3 种基金the foundation for Excellent Youth Scholars of CAREERI, CAS (51Y251B51)the SKLCS foundation (Grant No. SKLCSZZ-2012-01-01)the National Basic Research Program of China (2010CB951003, 2010CB951404)the Knowledge Innovation Project of the Chinese Academy of Sciences (KZCX2-EW-311)
文摘Aerosol samples were collected at altitudes from 584 m a.s.l.to 3,804 m a.s.l.at seven sites of the eastern Tianshan.The occurrence,distribution,and possible sources of 47 trace metals—including alkali metals and alkali earth metals,transition metals,lanthanoids,and heavy metals—were investigated.It was found that four sampling sites(Shuinichang,1,691 m a.s.l.;Urumqi City,809 m a.s.l.;Fu Kang Station,584 m a.s.l.;and Bogeda Glacier No.4,3,613 m a.s.l.)were contaminated mainly by heavy metals.Other three high-altitude sites(Urumqi Glacier No.1,3,804 m a.s.l.;Wang Feng road-maintenance station,3,039 m a.s.l.;and Tianshan Glaciology Station,2,135 m a.s.l.)were not polluted.The aerosol particles were clustered into two dominant types:crust-originated particles and pollution-derived particles.Aerosols from UG1,WF,and TGS were characterized by crust-originated particles such as clay,plagioclase,dolomite,alkali feldspar,and biotite;while those from SNC,Urumqi,FK,and BG4 were characterized by high content of Cl-rich particles,S-rich particles,and soot.The backward-trajectories results indicated that air masses arriving at SNC,Urumqi,FK,and BG4 were identified as the more polluted source,when compared to the short-range air mass transport from the North to UGI and WF.Relatively lower altitude,as well as terrain blocking,might be another important reason for the gradient difference in pollution influence among these seven places in the Urumqi River Basin.
