Patent foramen ovale(PFO)is a remnant of normal fetal anatomy,which occurs in about 20%–25%of cases.Patients with PFO are at increased risk for migraine,acute limb ischemia secondary to emboli and cryptogenic(no othe...Patent foramen ovale(PFO)is a remnant of normal fetal anatomy,which occurs in about 20%–25%of cases.Patients with PFO are at increased risk for migraine,acute limb ischemia secondary to emboli and cryptogenic(no other identifiable cause)stroke.The traditional approach has been to use a fluoroscopically guided blocking device,but this is contraindicated in patients with severe allergies to contrast media or inability to undergo angiography.With the advancements in technology,ultrasonic robotic systems have become available for medical procedures.In the current study,we reported a case of using the ultrasonic robotic teleoperation system to achieve closure of PFO at the Chinese PLA General Hospital,Beijing,China.展开更多
Backgrounds:Previous surveys have found that children with iron deficiency(ID)were likely to suffer from early childhood caries(ECC).We aimed to assess the scientific evidence about whether ID is intrinsically related...Backgrounds:Previous surveys have found that children with iron deficiency(ID)were likely to suffer from early childhood caries(ECC).We aimed to assess the scientific evidence about whether ID is intrinsically related to ECC.Methods:The medical subject headings(MeSH)terms and free words were searched on PubMed,Web of Science,Cochrane,China National Knowledge Infrastructure,Wanfang,and the Database for Chinese Technical Periodicals from March 2020 to September 2020.Two researchers independently screened the articles.Data extraction and cross-checking were performed for the studies that met the inclusion criteria.Meta-analysis was performed using the Cochrane Collaboration’s Review Manager 5.3 software.Results:After excluding duplication and irrelevant literature,12 case-control studies were included in the study.The meta-analysis demonstrated that children with ECC were more likely to have ID(odds ratio[OR]=2.63,95%confidence interval[CI]:[1.85,3.73],P<0.001).There was no statistically significant association found between the level of serum ferritin and ECC(weighted mean difference(WMD)=5.80,95%CI:[11.97,0.37],P=0.07).Children with ECC were more likely to have iron-deficiency anemia(OR=2.74,95%CI:[2.41,3.11],P<0.001).The hemoglobin(HGB)levels in the ECC group were significantly lower compared with that in the ECC-free group(WMD=9.96,95%CI:[15.45,4.46],P=0.0004).The mean corpuscular volume(MCV)levels in the ECC group were significantly lower compared with that in the ECC-free group(WMD=3.72,95%CI:[6.65,0.79],P=0.01).Conclusions:ID was more prevalent in children with ECC,and the markers of iron status in the ECC group,such as serum ferritin,HGB,and MCV,were relatively lower than the ECC-free group.展开更多
基金the National Key Research and Development Program(2021YFC2501106)the Key Discipline Construction Project of Chinese PLA Medical College during the 13^(th) Five-Year Plan Period(A350109).
文摘Patent foramen ovale(PFO)is a remnant of normal fetal anatomy,which occurs in about 20%–25%of cases.Patients with PFO are at increased risk for migraine,acute limb ischemia secondary to emboli and cryptogenic(no other identifiable cause)stroke.The traditional approach has been to use a fluoroscopically guided blocking device,but this is contraindicated in patients with severe allergies to contrast media or inability to undergo angiography.With the advancements in technology,ultrasonic robotic systems have become available for medical procedures.In the current study,we reported a case of using the ultrasonic robotic teleoperation system to achieve closure of PFO at the Chinese PLA General Hospital,Beijing,China.
基金Qingdao People’s Livelihood Science and Technology Plan Project Descrip-tion(No.19-6-1-33-nsh).
文摘Backgrounds:Previous surveys have found that children with iron deficiency(ID)were likely to suffer from early childhood caries(ECC).We aimed to assess the scientific evidence about whether ID is intrinsically related to ECC.Methods:The medical subject headings(MeSH)terms and free words were searched on PubMed,Web of Science,Cochrane,China National Knowledge Infrastructure,Wanfang,and the Database for Chinese Technical Periodicals from March 2020 to September 2020.Two researchers independently screened the articles.Data extraction and cross-checking were performed for the studies that met the inclusion criteria.Meta-analysis was performed using the Cochrane Collaboration’s Review Manager 5.3 software.Results:After excluding duplication and irrelevant literature,12 case-control studies were included in the study.The meta-analysis demonstrated that children with ECC were more likely to have ID(odds ratio[OR]=2.63,95%confidence interval[CI]:[1.85,3.73],P<0.001).There was no statistically significant association found between the level of serum ferritin and ECC(weighted mean difference(WMD)=5.80,95%CI:[11.97,0.37],P=0.07).Children with ECC were more likely to have iron-deficiency anemia(OR=2.74,95%CI:[2.41,3.11],P<0.001).The hemoglobin(HGB)levels in the ECC group were significantly lower compared with that in the ECC-free group(WMD=9.96,95%CI:[15.45,4.46],P=0.0004).The mean corpuscular volume(MCV)levels in the ECC group were significantly lower compared with that in the ECC-free group(WMD=3.72,95%CI:[6.65,0.79],P=0.01).Conclusions:ID was more prevalent in children with ECC,and the markers of iron status in the ECC group,such as serum ferritin,HGB,and MCV,were relatively lower than the ECC-free group.
