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Excellent outcome of primary Neisseria meningitidis keratoconjunctivitis
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作者 Jakiyah Daud siti raihan ishak +1 位作者 Zakuan Zainy Deris Wan Hazabbah Wan Hitam 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2011年第5期419-420,共2页
Infectious conjunctivitis is a very common presentation to medical professional and ophthalmologist all over the world.Although its typically self-limiting and treatable in almost all of the cases,but we need to be aw... Infectious conjunctivitis is a very common presentation to medical professional and ophthalmologist all over the world.Although its typically self-limiting and treatable in almost all of the cases,but we need to be aware of the rare and potentially life threatening if the cause is not promptly identified and treated accordingly.In our case report,we highlighted the rare case of Neisseria meningitidis as a primary cause of keratoconjunctivitis.Neisseria meningitidis is a rare etiology of keratoconjunctivitis and its ocular presentations are quite similar with other bacterial or viral infection.The infection may potentially fatal if systemic invasion occurred,however with immediate and proper treatment the outcome is satisfactory.Early diagnosis and proper antibiotic treatment are critical to prevent systemic spread of the infection.Public health intervention is needed to prevent outbreak of the disease. 展开更多
关键词 Neisseria MENINGITIDIS KERATOCONJUNCTIVITIS
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免疫功能正常少年患早期表现为复视的隐球菌脑膜炎1例(英文)
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作者 Yanti Muslikhan Wan Hazabbah Wan Hitam +2 位作者 siti raihan ishak Ibrahim Mohtar John Takaran 《国际眼科杂志》 CAS 2010年第3期421-423,共3页
目的:报告免疫力正常少年的隐球菌脑膜炎1例,早期表现为复视和双眼视力低下。方法:病例报告。结果:男,17岁,两眼视物模糊并复视3wk,伴随严重的搏动性头痛、恶心、呕吐及低热。经体格检查无发热及假性脑膜炎迹象。双眼视力为6/15并视野... 目的:报告免疫力正常少年的隐球菌脑膜炎1例,早期表现为复视和双眼视力低下。方法:病例报告。结果:男,17岁,两眼视物模糊并复视3wk,伴随严重的搏动性头痛、恶心、呕吐及低热。经体格检查无发热及假性脑膜炎迹象。双眼视力为6/15并视野缩窄。双眼前段正常。眼外肌运动表明双侧第六神经麻痹。眼底检查显示双侧视盘充血和轻度隆起。CT扫描大脑正常,无颅内肿块或脑室异常。腰椎穿刺发现高开放压>300mmH2O。脑脊液显微镜下及培养均存在新型隐球菌。本例由神经医疗组联合处理。患者开始静脉注射两性霉素B和氟康唑,神经症状1wk后恢复,双眼视力提高到6/6,同时周边视野恢复。随着第六神经麻痹的康复双眼复视得到好转。结论:本例强调了隐球菌脑膜炎进展缓慢的性质。即使免疫功能正常,也不会存在明显的假性脑膜炎特征,复视可能是脑膜炎患者的早期表现之一。 展开更多
关键词 隐球菌脑膜炎 视乳头水肿 双侧第六神经麻痹
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Matrix regeneration therapy:a solution to enhance healing in fungal keratitis
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作者 siti raihan ishak Ahmad Nurfahmi Akhtar Ali +3 位作者 Hayati Abdul Aziz Mohtar Ibrahim Denis Barritault Wan Hazabbah Wan Hitam 《Journal of Coastal Life Medicine》 2014年第1期49-52,共4页
Corneal ulcers,especially of fungal origin,are a relatively common clinical entity within the spectrum of keratitis in tropical countries.The persistence of a non-healing epithelial defect is a known complication of t... Corneal ulcers,especially of fungal origin,are a relatively common clinical entity within the spectrum of keratitis in tropical countries.The persistence of a non-healing epithelial defect is a known complication of these ulcers.Despite advances in medical therapy,the management of this condition is still challenging.CACICOL20^(®)is a new ophthalmic matrix therapy that has been proved efficient as a corneal healing agent.To the best of our knowledge there have been reports of the limited use of matrix therapy in ocular healing,specifically in fungal keratitis.We report 2 cases of the efficacy of it as an adjuvant to topical amphotericin B in treating non-healing epithelial defects secondary to fungal corneal ulcers. 展开更多
关键词 Fungal ulcer Non healing epithelial defect Matrix regeneration therapy
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