High‑grade gliomas are the most common type of brain tumors.Of these,glioblastoma account for 60-70%and despite treatment carries a dismal prognosis.Postoperative surgical site infection has been associated with prolo...High‑grade gliomas are the most common type of brain tumors.Of these,glioblastoma account for 60-70%and despite treatment carries a dismal prognosis.Postoperative surgical site infection has been associated with prolonged survival.Herewith,we present a case of glioblastoma and a case of anaplastic oligoastrocytoma that developed postoperative infection of the surgical site and had prolonged survival.A thorough literature review is also presented.展开更多
Aim:Several epidemiological studies have shown an inverse correlation between allergy and brain cancer.The purpose of this study was to compare the serum IgE levels between patients with gliomas and nonglial tumors an...Aim:Several epidemiological studies have shown an inverse correlation between allergy and brain cancer.The purpose of this study was to compare the serum IgE levels between patients with gliomas and nonglial tumors and their possible prognostic role.Methods:A total of 84 patients with intracranial tumors were included in this study.At clinical presentation,estimation of serum IgE levels was assessed by nephelometry.Detailed information regarding the history of allergies was collected by interview.Results:Of the 84 cases,42 were gliomas,23 were meningiomas,16 were metastases and 3 were primary central nervous system lymphomas.Patients with high‑grade glioma had lower IgE levels than patients with low‑grade glioma.Patients with glioma and meningioma had statistical significant lower serum IgE levels than patients with metastases.Patients with glioblastoma with serum IgE levels greater than 24 U/mL had a better survival.Conclusion:Patients with glioma and meningioma had lower IgE levels than patients with metastatic lesions.A prognostic role of serum IgE levels was found in glioblastoma.Further studies in larger patient series are required in order to verify our preliminary observations.展开更多
文摘High‑grade gliomas are the most common type of brain tumors.Of these,glioblastoma account for 60-70%and despite treatment carries a dismal prognosis.Postoperative surgical site infection has been associated with prolonged survival.Herewith,we present a case of glioblastoma and a case of anaplastic oligoastrocytoma that developed postoperative infection of the surgical site and had prolonged survival.A thorough literature review is also presented.
文摘Aim:Several epidemiological studies have shown an inverse correlation between allergy and brain cancer.The purpose of this study was to compare the serum IgE levels between patients with gliomas and nonglial tumors and their possible prognostic role.Methods:A total of 84 patients with intracranial tumors were included in this study.At clinical presentation,estimation of serum IgE levels was assessed by nephelometry.Detailed information regarding the history of allergies was collected by interview.Results:Of the 84 cases,42 were gliomas,23 were meningiomas,16 were metastases and 3 were primary central nervous system lymphomas.Patients with high‑grade glioma had lower IgE levels than patients with low‑grade glioma.Patients with glioma and meningioma had statistical significant lower serum IgE levels than patients with metastases.Patients with glioblastoma with serum IgE levels greater than 24 U/mL had a better survival.Conclusion:Patients with glioma and meningioma had lower IgE levels than patients with metastatic lesions.A prognostic role of serum IgE levels was found in glioblastoma.Further studies in larger patient series are required in order to verify our preliminary observations.
