射麻口服液是国医大师金世元教授经典验方,经过长期临床实践,临床疗效突出,主治外邪犯肺、入里化热而导致的呼吸系统疾病,具有清热化痰、止咳平喘的功效,临床常用于慢阻肺中医辨证为痰热壅肺证的患者。对于现阶段临床工作而言,其说明书...射麻口服液是国医大师金世元教授经典验方,经过长期临床实践,临床疗效突出,主治外邪犯肺、入里化热而导致的呼吸系统疾病,具有清热化痰、止咳平喘的功效,临床常用于慢阻肺中医辨证为痰热壅肺证的患者。对于现阶段临床工作而言,其说明书的指导作用有待完善,且目前尚无遵循循证医学方法制定的共识或指南详细规范本药品的临床应用。通过文献检索与梳理、名老中医访谈及临床问题调研,并通过2轮次德尔菲法问卷调查及名义群体法(Nominal group technique, NGT)专家投票表决,最终形成行业标准《射麻口服液治疗慢性阻塞性肺疾病临床应用专家共识》,共识明确提出了射麻口服液治疗慢性阻塞性肺疾病的疾病定位、中医辨证分型、用药方案、疗效特点、不良反应、禁忌及特殊人群用药等临床应用关键性问题,以规范射麻口服液治疗慢性阻性肺疾病的临床应用,促进合理用药,提高临床疗效,推动中成药临床应用规范化进程。展开更多
OBJECTIVE:To formulate the first clinical practice guideline for the treatment of cough using Chinese medicine based on the grading of recommendations assessment,development,and evaluation(GRADE)systematic approach,in...OBJECTIVE:To formulate the first clinical practice guideline for the treatment of cough using Chinese medicine based on the grading of recommendations assessment,development,and evaluation(GRADE)systematic approach,including clinical evidence,evaluation of ancient literature,and expert consensus.METHODS:In the process of development,the regulation of"evidence-based,consensus-assisted,and empirical"was followed,and a comprehensive systematic approach of recommendation assessment,GRADE,evidence-based evaluation,expert consensus,and the Delphi method was used.In the process of guideline development,evidence-based evaluation of ancient literature was included for the first time,and clinical evidence was fully integrated with clinical expert consensus.RESULTS:The clinical practice guidelines for the treatment of cough with Chinese herbal medicine were developed after a comprehensive consideration of evidence-based evaluation and expert opinions.The guideline recommendations focused on recommending herbal compound decoctions and Chinese patent medicines for cough in different conditions.Based on the GRADE systematic approach,we conducted an evidence-based evaluation of the recommended Chinese patent medicines one by one;meanwhile,the expert consensus method was used to unify the recommendations of both.CONCLUSION:Based on clinical evidence,ancient literature evaluation,and expert consensus,a clinical practice guideline for Traditional Chinese Medicine(TCM)in the treatment of cough was developed,providing the first current clinical practice guideline for domestic and foreign TCM and Western medicine practitioners,especially respiratory professionals at home and abroad.展开更多
文摘射麻口服液是国医大师金世元教授经典验方,经过长期临床实践,临床疗效突出,主治外邪犯肺、入里化热而导致的呼吸系统疾病,具有清热化痰、止咳平喘的功效,临床常用于慢阻肺中医辨证为痰热壅肺证的患者。对于现阶段临床工作而言,其说明书的指导作用有待完善,且目前尚无遵循循证医学方法制定的共识或指南详细规范本药品的临床应用。通过文献检索与梳理、名老中医访谈及临床问题调研,并通过2轮次德尔菲法问卷调查及名义群体法(Nominal group technique, NGT)专家投票表决,最终形成行业标准《射麻口服液治疗慢性阻塞性肺疾病临床应用专家共识》,共识明确提出了射麻口服液治疗慢性阻塞性肺疾病的疾病定位、中医辨证分型、用药方案、疗效特点、不良反应、禁忌及特殊人群用药等临床应用关键性问题,以规范射麻口服液治疗慢性阻性肺疾病的临床应用,促进合理用药,提高临床疗效,推动中成药临床应用规范化进程。
基金National Key R&D Plan:Development of International Standards for Traditional Chinese Medicine Technology(No.2019YFC1712003)。
文摘OBJECTIVE:To formulate the first clinical practice guideline for the treatment of cough using Chinese medicine based on the grading of recommendations assessment,development,and evaluation(GRADE)systematic approach,including clinical evidence,evaluation of ancient literature,and expert consensus.METHODS:In the process of development,the regulation of"evidence-based,consensus-assisted,and empirical"was followed,and a comprehensive systematic approach of recommendation assessment,GRADE,evidence-based evaluation,expert consensus,and the Delphi method was used.In the process of guideline development,evidence-based evaluation of ancient literature was included for the first time,and clinical evidence was fully integrated with clinical expert consensus.RESULTS:The clinical practice guidelines for the treatment of cough with Chinese herbal medicine were developed after a comprehensive consideration of evidence-based evaluation and expert opinions.The guideline recommendations focused on recommending herbal compound decoctions and Chinese patent medicines for cough in different conditions.Based on the GRADE systematic approach,we conducted an evidence-based evaluation of the recommended Chinese patent medicines one by one;meanwhile,the expert consensus method was used to unify the recommendations of both.CONCLUSION:Based on clinical evidence,ancient literature evaluation,and expert consensus,a clinical practice guideline for Traditional Chinese Medicine(TCM)in the treatment of cough was developed,providing the first current clinical practice guideline for domestic and foreign TCM and Western medicine practitioners,especially respiratory professionals at home and abroad.
