The control of large deformation problems in layered soft rock tunnels needs to solve urgently.The roof problem is particularly severe among the deformation issues in tunnels.This study first analyzes the asymmetric d...The control of large deformation problems in layered soft rock tunnels needs to solve urgently.The roof problem is particularly severe among the deformation issues in tunnels.This study first analyzes the asymmetric deformation modes in layered soft rock tunnels with large deformations.Subsequently,we construct a mechanical model under ideal conditions for controlling the roof of layered soft rock tunnels through high preload with the support of NPR anchor cables.The prominent roles of long and short NPR anchor cables in the support system are also analyzed.The results indicate the significance of high preload in controlling the roof of layered soft rock tunnels.The short NPR anchor cables effectively improve the integrity of the stratified soft rock layers,while the long NPR anchor cables effectively mobilize the self-bearing capacity of deep-stable rock layers.Finally,the high-preload support method with NPR anchor cables is validated to have a good effect on controlling large deformations in layered soft rock tunnels through field monitoring data.展开更多
Refined 3D modeling of mine slopes is pivotal for precise prediction of geological hazards.Aiming at the inadequacy of existing single modeling methods in comprehensively representing the overall and localized charact...Refined 3D modeling of mine slopes is pivotal for precise prediction of geological hazards.Aiming at the inadequacy of existing single modeling methods in comprehensively representing the overall and localized characteristics of mining slopes,this study introduces a new method that fuses model data from Unmanned aerial vehicles(UAV)tilt photogrammetry and 3D laser scanning through a data alignment algorithm based on control points.First,the mini batch K-Medoids algorithm is utilized to cluster the point cloud data from ground 3D laser scanning.Then,the elbow rule is applied to determine the optimal cluster number(K0),and the feature points are extracted.Next,the nearest neighbor point algorithm is employed to match the feature points obtained from UAV tilt photogrammetry,and the internal point coordinates are adjusted through the distanceweighted average to construct a 3D model.Finally,by integrating an engineering case study,the K0 value is determined to be 8,with a matching accuracy between the two model datasets ranging from 0.0669 to 1.0373 mm.Therefore,compared with the modeling method utilizing K-medoids clustering algorithm,the new modeling method significantly enhances the computational efficiency,the accuracy of selecting the optimal number of feature points in 3D laser scanning,and the precision of the 3D model derived from UAV tilt photogrammetry.This method provides a research foundation for constructing mine slope model.展开更多
An extra-large landslide occurred on June 19,2021,on the footwall slope of the Nanfen Open-pit Iron Mine in Liaoning Province,China,with a volume of approximately 1.2×107 m3.To elucidate the causative factors,dev...An extra-large landslide occurred on June 19,2021,on the footwall slope of the Nanfen Open-pit Iron Mine in Liaoning Province,China,with a volume of approximately 1.2×107 m3.To elucidate the causative factors,development process,and destructive mechanisms of this catastrophic landslide,comprehensive field tests,investigations,and laboratory experiments were conducted.Initially,the heavily weathered rock mass of the slope was intersected by faults and joint fissures,facilitating rainwater infiltration.Moreover,the landslide contained a substantial clay mineral with highly developed micro-cracks and micro-pores,exhibiting strong water-absorption properties.As moisture content increased,the rock mass underwent softening,resulting in reduced strength.Ultimately,continuous heavy rainfall infiltration amplified the slope's weight,diminishing the weak structural plane's strength,leading to fracture propagation,slip plane penetration,and extensive tensile-shear and uplift failure of the slope.The study highlights poor geological conditions as the decisive factor for this landslide,with continuous heavy rainfall as the triggering factor.Presently,adverse environmental factors persistently affect the landslide,and deformation and failure continue to escalate.Hence,it is imperative to urgently implement integrated measures encompassing slope reinforcement,monitoring,and early-warning to real-time monitor the landslide's deformation and deep mechanical evolution trends.展开更多
To investigate the mechanical failure characteristics of volcanic breccia with different bedding dip angles in deep layers,triaxial compression experiments were conducted on specimens taken from volcanic rock layers i...To investigate the mechanical failure characteristics of volcanic breccia with different bedding dip angles in deep layers,triaxial compression experiments were conducted on specimens taken from volcanic rock layers in the Junggar Basin,Xinjiang.By changing the confining pressure,we compared the mechanical properties,acoustic emission characteristics,and fractal features of the acoustic emission sequence for volcanic breccia with different bedding dip angles.The research results indicate that as the bedding dip angle increases,peak strength,internal friction angle,and cohesion exhibit a“U-shaped”variation pattern.The correlation dimension of the acoustic emission amplitude was calculated using the G-P algorithm,revealing that volcanic breccia exhibits fractal characteristics.Furthermore,a positive correlation between the correlation dimension and the bedding dip angle was observed.When the stress of the test specimen reaches 0.8σ_(c),there is a significant decrease in the fractal dimension,serving as a criterion for predicting the failure of the specimen.By analyzing the changes in fractal dimension at different stress levels,the slope of the fractal dimension△D<-0.5 can be used as a precursor to failure for test specimens with a bedding dip angle of 15°≤β≤45°.Similarly,when the bedding dip angle of the specimen is 0°≤β<15°or 45°<β≤90°,△D<0 can be considered as a precursor to specimen failure.This study provides theoretical references for understanding the failure patterns of volcanic rock.展开更多
Objective To observe changes of plain MR T1WI signal intensity of dentate nucleus in nasopharyngeal carcinoma patients after radiotherapy and multiple times of intravenous injection of gadolinium-based contrast agent(...Objective To observe changes of plain MR T1WI signal intensity of dentate nucleus in nasopharyngeal carcinoma patients after radiotherapy and multiple times of intravenous injection of gadolinium-based contrast agent(GBCA).Methods Fifty patients with pathologically confirmed nasopharyngeal carcinoma and received intensity-modulated radiotherapy were retrospectively enrolled as the nasopharyngeal carcinoma group,and 50 patients with other malignant tumors and without history of brain radiotherapy were retrospectively enrolled as the control group.All patients received yearly GBCA enhanced MR examinations for the nasopharynx or the head.T1WI signal intensities of the dentate nucleus and the pons on same plane were measured based on images in the year of confirmed diagnosis(recorded as the first year)and in the second to the fifth years.T1WI signal intensity ratio of year i(ranging from 1 to 5)was calculated with values of dentate nucleus divided by values of the pons(ΔSI i),while the percentage of relative changes of year j(ranging from 2 to 5)was calculated withΔSI j compared toΔSI 1(Rchange j).The values of these two parameters were compared,and the correlation ofΔSI and GBCA injection year-time was evaluated within each group.Results No significant difference of gender,age norΔSI 1 was found between groups(all P>0.05).The second to the fifth yearΔSI and Rchange in nasopharyngeal carcinoma group were all higher than those in control group(all P<0.05).Within both groups,ΔSI was positively correlated with GBCA injection year-time(both P<0.05).Conclusion Patients with nasopharyngeal carcinoma who underwent radiotherapy and multiple times of intravenous injection of GBCA tended to be found with gradually worsening GBCA deposition in dentate nucleus,for which radiotherapy might be a risk factor.展开更多
文摘目的构建并验证多灶性甲状腺乳头状癌(multifocal papillary thyroid carcinoma,MPTC)高容量淋巴结转移(high-volume lymph node metastasis,HVM)的列线图预测模型。方法选取2010年1月至2024年1月于杭州市第一人民医院(A中心)及杭州市肿瘤医院(B中心)分别确诊的1146例和234例MPTC患者作为研究对象。A中心患者以7:3的比例采用随机数字表法分成训练集(n=803)和测试集(n=343),B中心34例患者作为外部验证集。通过单因素和多因素Logistic回归分析在训练集中筛选HVM的独立风险因素,并构建列线图预测模型,测试集和外部验证集用以评价模型的泛化能力,通过受试者操作特征曲线下面积(area under the curve,AUC)、敏感度、特异性评价模型的区分能力。结果A中心和B中心发生HVM的概率分别为13.3%和12.8%。单因素及多因素Logistic回归显示,男性(OR=2.91,95%CI:1.835~4.599)、病灶最大径(OR=1.05,95%CI:1.021~1.070)和年龄(OR=0.95,95%CI:0.936~0.972)均为发生HVM的独立风险因素。基于独立风险因素构建列线图预测模型,AUC、敏感度和特异性在训练集中分别为0.767、72.6%和70.2%,在测试集中分别为0.838、94.9%和68.4%,在外部验证集中分别为0.769、63.3%和84.3%。校准曲线显示与理想曲线具有良好的一致性。结论基于临床风险因素构建的预测模型可有效预测MPTC患者发生HVM的概率。
基金financial support from the Second Tibetan Plateau Scientific Expedition and Research Program(STEP)(No.2019QZKK0708)the National Natural Science Foundation of China(No.41941018)the Special Fund of Yueqi Scholars(No.800015Z1207).
文摘The control of large deformation problems in layered soft rock tunnels needs to solve urgently.The roof problem is particularly severe among the deformation issues in tunnels.This study first analyzes the asymmetric deformation modes in layered soft rock tunnels with large deformations.Subsequently,we construct a mechanical model under ideal conditions for controlling the roof of layered soft rock tunnels through high preload with the support of NPR anchor cables.The prominent roles of long and short NPR anchor cables in the support system are also analyzed.The results indicate the significance of high preload in controlling the roof of layered soft rock tunnels.The short NPR anchor cables effectively improve the integrity of the stratified soft rock layers,while the long NPR anchor cables effectively mobilize the self-bearing capacity of deep-stable rock layers.Finally,the high-preload support method with NPR anchor cables is validated to have a good effect on controlling large deformations in layered soft rock tunnels through field monitoring data.
基金funded by National Natural Science Foundation of China(Grant Nos.42272333,42277147).
文摘Refined 3D modeling of mine slopes is pivotal for precise prediction of geological hazards.Aiming at the inadequacy of existing single modeling methods in comprehensively representing the overall and localized characteristics of mining slopes,this study introduces a new method that fuses model data from Unmanned aerial vehicles(UAV)tilt photogrammetry and 3D laser scanning through a data alignment algorithm based on control points.First,the mini batch K-Medoids algorithm is utilized to cluster the point cloud data from ground 3D laser scanning.Then,the elbow rule is applied to determine the optimal cluster number(K0),and the feature points are extracted.Next,the nearest neighbor point algorithm is employed to match the feature points obtained from UAV tilt photogrammetry,and the internal point coordinates are adjusted through the distanceweighted average to construct a 3D model.Finally,by integrating an engineering case study,the K0 value is determined to be 8,with a matching accuracy between the two model datasets ranging from 0.0669 to 1.0373 mm.Therefore,compared with the modeling method utilizing K-medoids clustering algorithm,the new modeling method significantly enhances the computational efficiency,the accuracy of selecting the optimal number of feature points in 3D laser scanning,and the precision of the 3D model derived from UAV tilt photogrammetry.This method provides a research foundation for constructing mine slope model.
基金supported by the National Natural Science Foundation of China(Grant No.52074295)the State Key Laboratory for GeoMechanics and Deep Underground Engineering,China University of Mining&Technology,Beijing(Grant No.SKLGDUEK202217).
文摘An extra-large landslide occurred on June 19,2021,on the footwall slope of the Nanfen Open-pit Iron Mine in Liaoning Province,China,with a volume of approximately 1.2×107 m3.To elucidate the causative factors,development process,and destructive mechanisms of this catastrophic landslide,comprehensive field tests,investigations,and laboratory experiments were conducted.Initially,the heavily weathered rock mass of the slope was intersected by faults and joint fissures,facilitating rainwater infiltration.Moreover,the landslide contained a substantial clay mineral with highly developed micro-cracks and micro-pores,exhibiting strong water-absorption properties.As moisture content increased,the rock mass underwent softening,resulting in reduced strength.Ultimately,continuous heavy rainfall infiltration amplified the slope's weight,diminishing the weak structural plane's strength,leading to fracture propagation,slip plane penetration,and extensive tensile-shear and uplift failure of the slope.The study highlights poor geological conditions as the decisive factor for this landslide,with continuous heavy rainfall as the triggering factor.Presently,adverse environmental factors persistently affect the landslide,and deformation and failure continue to escalate.Hence,it is imperative to urgently implement integrated measures encompassing slope reinforcement,monitoring,and early-warning to real-time monitor the landslide's deformation and deep mechanical evolution trends.
基金funded by the National Natural Science Foundation of China(Grant Nos.52174096,42277174).
文摘To investigate the mechanical failure characteristics of volcanic breccia with different bedding dip angles in deep layers,triaxial compression experiments were conducted on specimens taken from volcanic rock layers in the Junggar Basin,Xinjiang.By changing the confining pressure,we compared the mechanical properties,acoustic emission characteristics,and fractal features of the acoustic emission sequence for volcanic breccia with different bedding dip angles.The research results indicate that as the bedding dip angle increases,peak strength,internal friction angle,and cohesion exhibit a“U-shaped”variation pattern.The correlation dimension of the acoustic emission amplitude was calculated using the G-P algorithm,revealing that volcanic breccia exhibits fractal characteristics.Furthermore,a positive correlation between the correlation dimension and the bedding dip angle was observed.When the stress of the test specimen reaches 0.8σ_(c),there is a significant decrease in the fractal dimension,serving as a criterion for predicting the failure of the specimen.By analyzing the changes in fractal dimension at different stress levels,the slope of the fractal dimension△D<-0.5 can be used as a precursor to failure for test specimens with a bedding dip angle of 15°≤β≤45°.Similarly,when the bedding dip angle of the specimen is 0°≤β<15°or 45°<β≤90°,△D<0 can be considered as a precursor to specimen failure.This study provides theoretical references for understanding the failure patterns of volcanic rock.
文摘Objective To observe changes of plain MR T1WI signal intensity of dentate nucleus in nasopharyngeal carcinoma patients after radiotherapy and multiple times of intravenous injection of gadolinium-based contrast agent(GBCA).Methods Fifty patients with pathologically confirmed nasopharyngeal carcinoma and received intensity-modulated radiotherapy were retrospectively enrolled as the nasopharyngeal carcinoma group,and 50 patients with other malignant tumors and without history of brain radiotherapy were retrospectively enrolled as the control group.All patients received yearly GBCA enhanced MR examinations for the nasopharynx or the head.T1WI signal intensities of the dentate nucleus and the pons on same plane were measured based on images in the year of confirmed diagnosis(recorded as the first year)and in the second to the fifth years.T1WI signal intensity ratio of year i(ranging from 1 to 5)was calculated with values of dentate nucleus divided by values of the pons(ΔSI i),while the percentage of relative changes of year j(ranging from 2 to 5)was calculated withΔSI j compared toΔSI 1(Rchange j).The values of these two parameters were compared,and the correlation ofΔSI and GBCA injection year-time was evaluated within each group.Results No significant difference of gender,age norΔSI 1 was found between groups(all P>0.05).The second to the fifth yearΔSI and Rchange in nasopharyngeal carcinoma group were all higher than those in control group(all P<0.05).Within both groups,ΔSI was positively correlated with GBCA injection year-time(both P<0.05).Conclusion Patients with nasopharyngeal carcinoma who underwent radiotherapy and multiple times of intravenous injection of GBCA tended to be found with gradually worsening GBCA deposition in dentate nucleus,for which radiotherapy might be a risk factor.
