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Coronary CT Angiography Using Low Iodine Delivery Rate and Tube Voltage Determined by Body Mass Index:Superiority in Clinical Practice 被引量:4
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作者 Wang YUAN ting-ting qu +4 位作者 Hui-juan WANG Mei-yu WANG Yuan qu Gang NIU Jian YANG 《Current Medical Science》 SCIE CAS 2019年第5期825-830,共6页
To explore the feasibility and superiority of iodine delivery rate(IDR)and tube voltage determined by patients'body mass index(BMI)in coronary CT angiography(CCTA),a total of 1567 patients undertaking CCTA during ... To explore the feasibility and superiority of iodine delivery rate(IDR)and tube voltage determined by patients'body mass index(BMI)in coronary CT angiography(CCTA),a total of 1567 patients undertaking CCTA during Feb.and Dec.2016 were enrolled and divided into two groups.In the control group,the IDR and tube voltage were fixed,while in the experimental group,the IDR and tube voltage were determined by patients,BMI.The volume of iodinated contrast media(ICM),extravasation rate,extravasation volume,extravasation recovery interval,incidence rate of adverse reactions,effective dose(ED)and image quality of the two groups were compared.The experiments demonstrated that the ICM volume,extravasation rate,extravasation volume,extravasation recovery interval,incidence of adverse reactions and ED were lower or shorter in the experimental group than in the control group,and the differences were statistically significant(all P<0.05).However,there were no significant differences in the mean CT value,image noise,signal to noise ratio and contrast to noise ratio between the two groups(all P<0.05),which were consistent with the diagnosticians*subjective evaluation outcomes.Our findings suggested that in CCTA,it is feasible to determine the IDR and tube voltage based on patients'BMI;low tube voltage and IDR are superior to the fixed tube voltage and IDR and are worthy of clinical promotion. 展开更多
关键词 iodinated contrast media IODINE delivery rate tube voltage ICM EXTRAVASATION ADVERSE REACTIONS
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Stress injuries and autophagy in mouse hippocampus after chronic cold exposure 被引量:1
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作者 ting-ting qu Jie-xin Deng +4 位作者 Rui-ling Li Zhan-jun Cui Xiao-qing Wang Lai Wang Jin-bo Deng 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第3期440-446,共7页
Cold exposure is an external stress factor that causes skin frostbite as well as a variety of diseases.Estrogen might participate in neuroprotection after cold exposure,but its precise mechanism remains unclear.In thi... Cold exposure is an external stress factor that causes skin frostbite as well as a variety of diseases.Estrogen might participate in neuroprotection after cold exposure,but its precise mechanism remains unclear.In this study,mice were exposed to 10°C for 7 days and 0–4°C for 30 days to induce a model of chronic cold exposure.Results showed that oxidative stress-related c-fos and cyclooxygenase 2 expressions,MAP1LC3-labeled autophagic cells,Iba1-labeled activated microglia,and interleukin-1β-positive pyramidal cells were increased in the hippocampal CA1 area.Chronic cold exposure markedly elevated the levels of estrogen in the blood and the estrogen receptor,G protein-coupled receptor 30.These results indicate that neuroimmunoreactivity is involved in chronic cold exposure-induced pathological alterations,including oxidative stress,neuronal autophagy,and neuroimmunoreactivity.Moreover,estrogen exerts a neuroprotective effect on cold exposure. 展开更多
关键词 海马CA1区 冷暴露 慢性 自噬 应激损伤 雌激素受体 白细胞介素-1Β 神经保护作用
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