Plant extracts from natural sources are an excellent choice for food additives and natural antioxidants.In this study,the active components of Tulipa edulis were extracted and analysed,and their antioxidant capacity w...Plant extracts from natural sources are an excellent choice for food additives and natural antioxidants.In this study,the active components of Tulipa edulis were extracted and analysed,and their antioxidant capacity was measured.Then,the crude extract mixture was separated and purified using a Sephadex LH-20 gel,and the antioxidant activity of the purified products was determined.Human umbilical vein endothelial human umbilical vein endothelial cells(HUVEC)cells were treated with 35 mmol/L glucose to construct a model of oxidative stress.Then,the cells were treated with the active component to observe whether the products of T.edulis could have a good protective effect on HUVEC cells induced by glucose.Transcriptome analysis was also performed on HUVEC cells after same treatment to explore the possible mechanism of the component F2 protecting HUVEC cells from oxidative stress induced by high glucose.The results showed that component F2 obtained from T.edulis has strong antioxidant activity.Moreover,F2 can play a strong antioxidant protective role in HUVEC cells.Meanwhile,the gene expression of heme oxygenase 1(HO-1),γ-glutamyl cysteine ligase catalytic subunit(GCLC)and NAD(P)H quinone oxidoreductase-1(NQO1)in HUVEC cells was up-regulated after treated with F2.This study provides reference value for the further development and application of T.edulis and the d evelopment of functional food.展开更多
To reveal some dynamic properties of the deploying process for the solar power satellite via an arbitrarily large phased array （SPS-ALPHA） solar receiver, the symplectic Runge-Kutta method is used to simulate the si...To reveal some dynamic properties of the deploying process for the solar power satellite via an arbitrarily large phased array （SPS-ALPHA） solar receiver, the symplectic Runge-Kutta method is used to simulate the simplified model with the consideration of the Rayleigh damping effect. The system containing the Rayleigh damping can be separated and transformed into the equivalent nondamping system formally to insure the application condition of the symplectic Runge-Kutta method. First, the Lagrange equation with the Rayleigh damping governing the motion of the system is derived via the variational principle. Then, with some reasonable assumptions on the relations among the damping, mass, and stiffness matrices, the Rayleigh damping system is equivalently converted into the nondamping system formally, so that the symplectic Runge-Kutta method can be used to simulate the deploying process for the solar receiver. Finally, some numerical results of the symplectic Runge-Kutta method for the dynamic properties of the solar receiver are reported. The numerical results show that the proposed simplified model is valid for the deploying process for the SPS-ALPHA solar receiver, and the symplectic Runge-Kutta method can preserve the displacement constraints of the system well with excellent long-time numerical stability.展开更多
Photoluminescence（PL） from bulk noble metals arises from the interband transition of bound electrons. Plasmonic nanostructures can greatly enhance the quantum yield of noble metals through the localized surface plas...Photoluminescence（PL） from bulk noble metals arises from the interband transition of bound electrons. Plasmonic nanostructures can greatly enhance the quantum yield of noble metals through the localized surface plasmon. In this work,we briefly review recent progress on the phenomenon, mechanism, and application of one-photon PL from plasmonic nanostructures. Particularly, our recent efforts in the study of the PL peak position, partial depolarization, and mode selection from plasmonic nanostructures can bring about a relatively complete and deep understanding of the physical mechanism of one-photon PL from plasmonic nanostructures, paving the way for future applications in plasmonic imaging,plasmonic nanolasing, and surface enhanced fluorescence spectra.展开更多
水系质子电池具有安全、环保、动力学快、成本低等优点,是一种很有前途的电化学储能系统.这些优点的实现依赖于开发合适且易于获取的电极材料.本文研究了微米尺度的H_(2)MoO_(3)/VPANI作为质子电池负极材料的高倍率性能和稳定性.与大多...水系质子电池具有安全、环保、动力学快、成本低等优点,是一种很有前途的电化学储能系统.这些优点的实现依赖于开发合适且易于获取的电极材料.本文研究了微米尺度的H_(2)MoO_(3)/VPANI作为质子电池负极材料的高倍率性能和稳定性.与大多数负极材料的赝电容性质相反,H_(2)MoO_(3)/PANI同时具有的高比容量和高倍率性能是基于扩散控制的电荷存储机制.H_(2)MoO_(3)/PANI电极在1.0 A g^(-1)时具有268.2 mAh g^(-1)的高比容量,在200.0 A g^(-1)的极高电流密度下也仍然具有高达50%的比容量保持率.本文详细分析了H_(2)MoO_(3)/PANI中超快质子传导的Grotthuss机制.基于H_(2)MoO_(3)/PANI构建的质子全电池在800.0 W kg^(-1)下的能量密度高达42.1 Wh kg^(-1).令人印象深刻的是,即使在冷冻电解质中,质子全电池仍然具有快速的质子传输能力,在-20℃保持了约70%的是室温比容量.这些优异的质子存储性能为微米尺度的电极材料在低温质子电池中的实际应用提供了重要见解.展开更多
Background:Tuberculosis(TB)is a major global health threat and the leading infectious disease cause of death worldwide.Access to and retention in TB care remains a challenge for patients,particularly those living in r...Background:Tuberculosis(TB)is a major global health threat and the leading infectious disease cause of death worldwide.Access to and retention in TB care remains a challenge for patients,particularly those living in rural and remote settings.This qualitative study explored barriers and facilitators to accessing and maintaining contact with TB care services in communities in Xigaze(Shigatse)prefecture,Xizang Autonomous Region(Tibet Autonomous Region),China from the perspective of persons impacted by TB.Methods:We conduced in-depth interviews with 23 participants impacted by TB in four rural districts in Xigaze prefecture,Xizang Autonomous Region,China between April 2019 and November 2020.Interviews were conducted in Tibetan and Mandarin,transcribed in Mandarin and translated into English.Transcripts were checked against recordings by native Tibetan and Mandarin speakers.QSR NVivo12 software was used for framework analysis guided by an access to care conceptual framework by Levesque et al.Results:Overall patients reported low awareness of and an indiferent attitude towards TB,although all reported understanding the need to adhere to treatment.Participants reported complex pathways to care,often requiring visits to multiple healthcare facilities.Some participants reported visiting traditional Tibetan medicine(TTM)providers.Participants reported various barriers to accessing care including challenges physically reaching care,out-of-pocket payments for tests,diagnostics and transport.Barriers to maintaining care included medication side efects and worry about treatment efectiveness.Enablers to accessing care identifed included knowledge or past experience with TB,integrated models of TTM and western care,supportive village doctors who conducted home visits,free TB treatment and other subsidies,as well as having family support with care and social support as barriers and facilitators to maintaining treatment.Conclusions:We identifed barriers and facilitators to accessing services in rural communities in Xigaze from the perspective of persons impacted by TB.Challenges include complex pathways to care,travel distances,wait times and low awareness.Tuberculosis care in the region could be strengthened by ongoing culturally tailored educational campaigns to increase awareness,partnerships with TTM providers,providing comprehensive treatment subsidies and strengthening the role of family members in comprehensive TB care.展开更多
Considerable attention has been paid recently to coherent control of plasmon resonances in metadevices for potential applications in all-optical light-with-light signal modulation and image processing.Previous reports...Considerable attention has been paid recently to coherent control of plasmon resonances in metadevices for potential applications in all-optical light-with-light signal modulation and image processing.Previous reports based on out-ofplane coherent control of plasmon resonances were established by modulating the position of a metadevice in standing waves.Here we show that destructive and constructive absorption can be realized in metallic nano-antennas through in-plane coherent control of plasmon resonances,which is determined by the distribution rule of electricalfield components of nano-antennas.We provide proof-of-principle demonstrations of plasmonic switching effects in a gold nanodisk monomer and dimer,and propose a plasmonic encoding strategy in a gold nanodisk chain.In-plane coherent control of plasmon resonances may open a new avenue toward promising applications in optical spectral enhancement,imaging,nanolasing,and optical communication in nanocircuits.展开更多
基金supported by the Open Grant of Beijing Advanced Innovation Center for Food Nutrition and Human Health(20182024)National Natural Science Foundation of China(31370104)+4 种基金The Natural Science Foundation of Hunan Province,China(2021JJ30029)the Taishan Scholar Program of Shandong Province,China(tsqn201909168)“Double Hundred”Program for Foreign Experts of Shandong Province,China(WST2017004)Hunan Province Postgraduate Education Innovation Project and Professional Capacity Enhancement(CX20200297)Project the Fundamental Research Funds for the Central Universities of Central South University(2020zzts424,2020zzts422)。
文摘Plant extracts from natural sources are an excellent choice for food additives and natural antioxidants.In this study,the active components of Tulipa edulis were extracted and analysed,and their antioxidant capacity was measured.Then,the crude extract mixture was separated and purified using a Sephadex LH-20 gel,and the antioxidant activity of the purified products was determined.Human umbilical vein endothelial human umbilical vein endothelial cells(HUVEC)cells were treated with 35 mmol/L glucose to construct a model of oxidative stress.Then,the cells were treated with the active component to observe whether the products of T.edulis could have a good protective effect on HUVEC cells induced by glucose.Transcriptome analysis was also performed on HUVEC cells after same treatment to explore the possible mechanism of the component F2 protecting HUVEC cells from oxidative stress induced by high glucose.The results showed that component F2 obtained from T.edulis has strong antioxidant activity.Moreover,F2 can play a strong antioxidant protective role in HUVEC cells.Meanwhile,the gene expression of heme oxygenase 1(HO-1),γ-glutamyl cysteine ligase catalytic subunit(GCLC)and NAD(P)H quinone oxidoreductase-1(NQO1)in HUVEC cells was up-regulated after treated with F2.This study provides reference value for the further development and application of T.edulis and the d evelopment of functional food.
基金supported by the National Natural Science Foundation of China(Nos.11432010,11672241,and 11502202)the Open Foundation of the State Key Laboratory of Structural Analysis of Industrial Equipment of China(No.GZ1605)
文摘To reveal some dynamic properties of the deploying process for the solar power satellite via an arbitrarily large phased array （SPS-ALPHA） solar receiver, the symplectic Runge-Kutta method is used to simulate the simplified model with the consideration of the Rayleigh damping effect. The system containing the Rayleigh damping can be separated and transformed into the equivalent nondamping system formally to insure the application condition of the symplectic Runge-Kutta method. First, the Lagrange equation with the Rayleigh damping governing the motion of the system is derived via the variational principle. Then, with some reasonable assumptions on the relations among the damping, mass, and stiffness matrices, the Rayleigh damping system is equivalently converted into the nondamping system formally, so that the symplectic Runge-Kutta method can be used to simulate the deploying process for the solar receiver. Finally, some numerical results of the symplectic Runge-Kutta method for the dynamic properties of the solar receiver are reported. The numerical results show that the proposed simplified model is valid for the deploying process for the SPS-ALPHA solar receiver, and the symplectic Runge-Kutta method can preserve the displacement constraints of the system well with excellent long-time numerical stability.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61675096 and 61205042)the Natural Science Foundation of Jiangsu Province in China(Grant No.BK20141393)the Singapore Ministry of Education Academic Research Fund Tier 3(Grant No.MOE2011-T3-1-005)and Tier 2(Grant No.MOE2012-T2-2-124)
文摘Photoluminescence（PL） from bulk noble metals arises from the interband transition of bound electrons. Plasmonic nanostructures can greatly enhance the quantum yield of noble metals through the localized surface plasmon. In this work,we briefly review recent progress on the phenomenon, mechanism, and application of one-photon PL from plasmonic nanostructures. Particularly, our recent efforts in the study of the PL peak position, partial depolarization, and mode selection from plasmonic nanostructures can bring about a relatively complete and deep understanding of the physical mechanism of one-photon PL from plasmonic nanostructures, paving the way for future applications in plasmonic imaging,plasmonic nanolasing, and surface enhanced fluorescence spectra.
基金supported by the National Natural Science Foundation of China(12274150,12274151)Natural Science Foundation of Hubei Province,China(2022CFB101,2022BAD061)。
文摘水系质子电池具有安全、环保、动力学快、成本低等优点,是一种很有前途的电化学储能系统.这些优点的实现依赖于开发合适且易于获取的电极材料.本文研究了微米尺度的H_(2)MoO_(3)/VPANI作为质子电池负极材料的高倍率性能和稳定性.与大多数负极材料的赝电容性质相反,H_(2)MoO_(3)/PANI同时具有的高比容量和高倍率性能是基于扩散控制的电荷存储机制.H_(2)MoO_(3)/PANI电极在1.0 A g^(-1)时具有268.2 mAh g^(-1)的高比容量,在200.0 A g^(-1)的极高电流密度下也仍然具有高达50%的比容量保持率.本文详细分析了H_(2)MoO_(3)/PANI中超快质子传导的Grotthuss机制.基于H_(2)MoO_(3)/PANI构建的质子全电池在800.0 W kg^(-1)下的能量密度高达42.1 Wh kg^(-1).令人印象深刻的是,即使在冷冻电解质中,质子全电池仍然具有快速的质子传输能力,在-20℃保持了约70%的是室温比容量.这些优异的质子存储性能为微米尺度的电极材料在低温质子电池中的实际应用提供了重要见解.
基金funded by TB REACH,a special initiative of Stop TB Partnership(Grant Number:STBP/TBREACH/GSA/W6–5).
文摘Background:Tuberculosis(TB)is a major global health threat and the leading infectious disease cause of death worldwide.Access to and retention in TB care remains a challenge for patients,particularly those living in rural and remote settings.This qualitative study explored barriers and facilitators to accessing and maintaining contact with TB care services in communities in Xigaze(Shigatse)prefecture,Xizang Autonomous Region(Tibet Autonomous Region),China from the perspective of persons impacted by TB.Methods:We conduced in-depth interviews with 23 participants impacted by TB in four rural districts in Xigaze prefecture,Xizang Autonomous Region,China between April 2019 and November 2020.Interviews were conducted in Tibetan and Mandarin,transcribed in Mandarin and translated into English.Transcripts were checked against recordings by native Tibetan and Mandarin speakers.QSR NVivo12 software was used for framework analysis guided by an access to care conceptual framework by Levesque et al.Results:Overall patients reported low awareness of and an indiferent attitude towards TB,although all reported understanding the need to adhere to treatment.Participants reported complex pathways to care,often requiring visits to multiple healthcare facilities.Some participants reported visiting traditional Tibetan medicine(TTM)providers.Participants reported various barriers to accessing care including challenges physically reaching care,out-of-pocket payments for tests,diagnostics and transport.Barriers to maintaining care included medication side efects and worry about treatment efectiveness.Enablers to accessing care identifed included knowledge or past experience with TB,integrated models of TTM and western care,supportive village doctors who conducted home visits,free TB treatment and other subsidies,as well as having family support with care and social support as barriers and facilitators to maintaining treatment.Conclusions:We identifed barriers and facilitators to accessing services in rural communities in Xigaze from the perspective of persons impacted by TB.Challenges include complex pathways to care,travel distances,wait times and low awareness.Tuberculosis care in the region could be strengthened by ongoing culturally tailored educational campaigns to increase awareness,partnerships with TTM providers,providing comprehensive treatment subsidies and strengthening the role of family members in comprehensive TB care.
基金the funding support from Singapore Ministry of Education Academic Research Fund Tier 2(grant number MOE2012-T2-2-124)and Tier 3(grant number MOE2011-T3-1-005)the funding support from the National Natural Science Foundation of China(grant numbers 61675096 and 61205042)+2 种基金the Natural Science Foundation of Jiangsu Province in China(grant number BK20141393)the funding support from Agency for Science,Technology and Research(A*STAR)SERC Pharos project(grant number 1527300025)A*STAR-JCO under project number 1437C00135.
文摘Considerable attention has been paid recently to coherent control of plasmon resonances in metadevices for potential applications in all-optical light-with-light signal modulation and image processing.Previous reports based on out-ofplane coherent control of plasmon resonances were established by modulating the position of a metadevice in standing waves.Here we show that destructive and constructive absorption can be realized in metallic nano-antennas through in-plane coherent control of plasmon resonances,which is determined by the distribution rule of electricalfield components of nano-antennas.We provide proof-of-principle demonstrations of plasmonic switching effects in a gold nanodisk monomer and dimer,and propose a plasmonic encoding strategy in a gold nanodisk chain.In-plane coherent control of plasmon resonances may open a new avenue toward promising applications in optical spectral enhancement,imaging,nanolasing,and optical communication in nanocircuits.
