Laser irradiation device for the protection of biological objects from the action of ionizing radiation to be used in practice has been manufactured (invention patent RU 2 428 228 C2). Research of the action of y-ra...Laser irradiation device for the protection of biological objects from the action of ionizing radiation to be used in practice has been manufactured (invention patent RU 2 428 228 C2). Research of the action of y-radiation itself as well as of the combined action of laser devices on survival, weight, skin and the general mitotic index of the bone marrow cells (mitotic index of all nucleus-containing cells of the bone marrow) of C57BL/6 experimental young mice was carried out. The mice were irradiated with ionizing (whole body irradiation) and laser radiation, separately one by one in a special frame device. Laser radiation in the dose 1 mJ/cm^2 irradiated only the back of a mouse, or both the back and the abdomen of mice. In case of combined irradiation of mice, the time interval between two types of irradiation did not exceed 30 min. First, the mice were exposed to y-radiation then to laser radiation. The method of the laser radiation-protection of biological subjects contributes to an increase in the viability of mice, prevents the damages of skin and also increases the mitotic activity of mice bone marrow cells.展开更多
An opportunity to use laser radiation as a means to reduce negative aftermath of acute and prolonged exposure to ionizing radiation was checked. The mice were exposed to γ- rays of ^60Co (whole body irradiation) in...An opportunity to use laser radiation as a means to reduce negative aftermath of acute and prolonged exposure to ionizing radiation was checked. The mice were exposed to γ- rays of ^60Co (whole body irradiation) in the dose of 7 Gy (the transitional clinical form of the acute radiation sickness). The dose rate at acute irradiation was 1.14 Gy/min, and at prolonged exposure, 0.027 Gy/min. Laser radiation in the dose l mJ/cm^2 was used to irradiate only the back of a mouse. First, the mice were exposed to γ-radiation, then to laser radiation. The time interval between two types of irradiation did not exceed 30 min. It was shown that the radiation protection of mice with laser radiation is possible at exposure to ionizing radiation in a wide dose interval and can reduce negative after-effects of both the acute and prolonged radiation exposure.展开更多
文摘Laser irradiation device for the protection of biological objects from the action of ionizing radiation to be used in practice has been manufactured (invention patent RU 2 428 228 C2). Research of the action of y-radiation itself as well as of the combined action of laser devices on survival, weight, skin and the general mitotic index of the bone marrow cells (mitotic index of all nucleus-containing cells of the bone marrow) of C57BL/6 experimental young mice was carried out. The mice were irradiated with ionizing (whole body irradiation) and laser radiation, separately one by one in a special frame device. Laser radiation in the dose 1 mJ/cm^2 irradiated only the back of a mouse, or both the back and the abdomen of mice. In case of combined irradiation of mice, the time interval between two types of irradiation did not exceed 30 min. First, the mice were exposed to y-radiation then to laser radiation. The method of the laser radiation-protection of biological subjects contributes to an increase in the viability of mice, prevents the damages of skin and also increases the mitotic activity of mice bone marrow cells.
文摘An opportunity to use laser radiation as a means to reduce negative aftermath of acute and prolonged exposure to ionizing radiation was checked. The mice were exposed to γ- rays of ^60Co (whole body irradiation) in the dose of 7 Gy (the transitional clinical form of the acute radiation sickness). The dose rate at acute irradiation was 1.14 Gy/min, and at prolonged exposure, 0.027 Gy/min. Laser radiation in the dose l mJ/cm^2 was used to irradiate only the back of a mouse. First, the mice were exposed to γ-radiation, then to laser radiation. The time interval between two types of irradiation did not exceed 30 min. It was shown that the radiation protection of mice with laser radiation is possible at exposure to ionizing radiation in a wide dose interval and can reduce negative after-effects of both the acute and prolonged radiation exposure.