Objective:This paper aims to compare the effect of skin staple suture and traditional silk suture in scalp suture surgery.Methods:A total of 80 craniocerebral surgery patients were included in this study,and the patie...Objective:This paper aims to compare the effect of skin staple suture and traditional silk suture in scalp suture surgery.Methods:A total of 80 craniocerebral surgery patients were included in this study,and the patients were randomly divided into observation group and control group,with 40 cases in each group.The observation group used disposable skin stapler to suture the scalp incision,and the control group used conventional silk suture to suture the incision.Statistical analysis was carried out on 6 indicators including suturing speed,healing under-scab,incision necrosis,incision cerebrospinal fluid(CSF)leakage,incision infection,and postoperative“centipede-shaped”scar incidence rate of the two suture methods.Results:There was no significant difference between the groups in terms of postoperative healing under-scab,incision necrosis,incision CSF leakage,and intracranial infection(P>0.05).The suturing speed in the observation group was 15.2±0.7 cm/min,which was significantly faster than 7.4±0.3 cm/min in the control group(P<0.05).The incidence of“centipede-shaped”scars in the observation group was significantly lower than that in the control group at 1 to 6 months after operation(P<0.05).Conclusion:Compared with traditional silk suture,skin staple suture has obvious advantages in suture speed and cosmetic effect.展开更多
The experimental model of traumatic brain injury was established in Sprague-Dawley rats according to Feeney’s free falling method.The brains were harvested at 2,6 and 24 hours,and at 3 and 5days after injury.Changes ...The experimental model of traumatic brain injury was established in Sprague-Dawley rats according to Feeney’s free falling method.The brains were harvested at 2,6 and 24 hours,and at 3 and 5days after injury.Changes in brain water content were determined using the wet and dry weights.Our results showed that water content of tissue significantly increased after traumatic brain injury,and reached minimum at 24 hours.Hematoxylin-eosin staining revealed pathological impairment of brain tissue at each time point after injury,particularly at 3 days,with nerve cell edema,degeneration,and necrosis observed,and the apoptotic rate significantly increased.Immunohistochemistry and western blot analysis revealed that the expression of occludin at the injured site gradually decreased as injury time advanced and reached a minimum at 3 days after injury;the expression of connexin 43 gradually increased as injury time advanced and reached a peak at 24 hours after injury.The experimental findings indicate that changes in occludin and connexin 43 expression were consistent with the development of brain edema,and may reflect the pathogenesis of brain injury.展开更多
文摘Objective:This paper aims to compare the effect of skin staple suture and traditional silk suture in scalp suture surgery.Methods:A total of 80 craniocerebral surgery patients were included in this study,and the patients were randomly divided into observation group and control group,with 40 cases in each group.The observation group used disposable skin stapler to suture the scalp incision,and the control group used conventional silk suture to suture the incision.Statistical analysis was carried out on 6 indicators including suturing speed,healing under-scab,incision necrosis,incision cerebrospinal fluid(CSF)leakage,incision infection,and postoperative“centipede-shaped”scar incidence rate of the two suture methods.Results:There was no significant difference between the groups in terms of postoperative healing under-scab,incision necrosis,incision CSF leakage,and intracranial infection(P>0.05).The suturing speed in the observation group was 15.2±0.7 cm/min,which was significantly faster than 7.4±0.3 cm/min in the control group(P<0.05).The incidence of“centipede-shaped”scars in the observation group was significantly lower than that in the control group at 1 to 6 months after operation(P<0.05).Conclusion:Compared with traditional silk suture,skin staple suture has obvious advantages in suture speed and cosmetic effect.
基金supported by the Natural Science Foundation of Guangdong Province,No.10151600101000002
文摘The experimental model of traumatic brain injury was established in Sprague-Dawley rats according to Feeney’s free falling method.The brains were harvested at 2,6 and 24 hours,and at 3 and 5days after injury.Changes in brain water content were determined using the wet and dry weights.Our results showed that water content of tissue significantly increased after traumatic brain injury,and reached minimum at 24 hours.Hematoxylin-eosin staining revealed pathological impairment of brain tissue at each time point after injury,particularly at 3 days,with nerve cell edema,degeneration,and necrosis observed,and the apoptotic rate significantly increased.Immunohistochemistry and western blot analysis revealed that the expression of occludin at the injured site gradually decreased as injury time advanced and reached a minimum at 3 days after injury;the expression of connexin 43 gradually increased as injury time advanced and reached a peak at 24 hours after injury.The experimental findings indicate that changes in occludin and connexin 43 expression were consistent with the development of brain edema,and may reflect the pathogenesis of brain injury.
